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Jurnal Klinik dan Riset Kesehatan (Journal of Clinical and Health Research) Bidang Pendidikan dan Penelitian, RSUD dr. Saiful Anwar Malang Jl. Jaksa Agung No. 2, Kec. Klojen, Malang 65112 Phone/Fax: 0341 – 362101 / 0341 - 369384 Email: jkrisk.rssa@gmail.com
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Jawa timur
INDONESIA
Jurnal Klinik dan Riset Kesehatan
Published by RSUD Dr. Saiful Anwar Malang
ISSN : 28092678     EISSN : 28090039     DOI : https://doi.org/10.11594/jk-risk
Core Subject : Health, Science,
Biochemistry, Genetics & Molecular Biology Health Professions Medicine & Pharmacology Nursing Public Health
Jurnal Klinik dan Riset Kesehatan (JK-RISK) – RSUD dr. Saiful Anwar Malang adalah jurnal open-access resmi yang dikelola oleh tim Penelitian dan Pendidikan Rumah Sakit Umum Daerah dr. Saiful Anwar Malang, Jawa Timur, Indonesia. JK-RISK menerbitkan satu volume yang terdiri atas tiga nomor setiap tahunnya yang diterbitkan pada bulan Oktober, Februari, dan Juni. JK-RISK hanya akan menerbitkan jurnal berbahasa Indonesia. Jurnal Klinik dan Riset Kesehatan – RSUD dr. Saiful Anwar Malang menerbitkan tulisan-tulisan ilmiah hasil penelitian, laporan kasus, tinjauan pustaka dalam bidang kedokteran dan kesehatan yang belum pernah diterbikan di jurnal manapun. Pernyataan kode etik publikasi JK-RISK merupakan pernyataan kode etik yang melibatkan pengelola jurnal, editor, mitra bestari serta penulis dalam proses publikasi jurnal ilmiah. Pernyataan kode etik didasarkan pada Peraturan Kepala LIPI Nomor 5 tahun 2014 tentang Kode Etik Publikasi Ilmiah yang menjunjung tinggi tiga nilai etik dalam publikasi, yaitu (i) Kenetralan, yang berarti terbebas dari pertentangan kepentingan dalam pengelolaan publikasi jurnal; (ii) Keadilan, dengan memberikan kebebasan hak kepengarangan kepada pengarang/penulis; dan (iii) Kejujuran, yang berarti bebas dari duplikasi, fabrikasi, falsifikasi dan plagiarisme (DF2P) dalam publikasi.
Arjuna Subject : Kedokteran - Kedokteran (Lain-Lain)
Articles 200 Documents
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Penundaan Stent pada Beban Trombus Tinggi: Sebuah Laporan Kasus Kurniawan, Catur; Widito, Sasmojo; Putri, V.Y.S
Jurnal Klinik dan Riset Kesehatan Vol 4 No 2 (2025): Edisi Februari
Publisher : RSUD Dr. Saiful Anwar Province of East Java

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.11594/jk-risk.04.2.8

Abstract

Direct stent implantation is widely recommended for the management of patients who have acute myocardial infarction with ST-segment elevation. However, in situations where there is HTB in the affected artery, stenting may increase the risk of no flow phenomenon. Delaying stenting may reduce complications. A 45-year-old man presented with symptoms suggestive of acute right ventricular infarction that started 8 hours before admission. The patient underwent an echocardiogram which showed an ejection fraction of 36%. Pre-PCI pharmacotherapy was administered. Coronary angiography showed a grade IV occlusion in the mid-LAD branch as well as a thrombus in the mid-RCA with TIMI 2 flow. Thrombus aspiration and balloon inflation were performed, but HTB persisted. DS was decided, with additional Enoxaparin 0. 6 cc twice daily. Subsequent angiography after 34 hours, showed CAD in three coronary artery branches with the RCA still showing complete occlusion with HTB. A stent implantation procedure was performed in the mid-RCA segment The final result achieved was TIMI 3 blood flow, with no residual stenosis. HTB can also be diagnosed based on the TIMI thrombus risk classification. The main goal of deferred stenting is to minimize complications such as the slow-flow phenomenon of distal embolization. It is important to emphasize that a routine DS strategy has not shown clear benefit and is not recommended.
Diagnosis dan Manajemen Obstruksi Jalan Napas Atas (Jackson 1) Akibat Infeksi Difteri pada Wanita Hamil Dwikarlina, Intan; Wijaya, Rendy; Yulia Rusmayanti, Mega; Antariksa, Genta; Candradikusuma, Didi
Jurnal Klinik dan Riset Kesehatan Vol 4 No 2 (2025): Edisi Februari
Publisher : RSUD Dr. Saiful Anwar Province of East Java

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.11594/jk-risk.04.2.9

Abstract

Diphtheria is an infectious disease caused by Corynebacterium diphtheria, which generally causes inflammation of the airways, leading to severe symptoms that can be life-threatening. Indonesia is listed as one of the ten countries with the highest cases of diphtheria worldwide. However, studies on cases of diphtheria infection, especially in the pregnant women population, have rarely been reported. A 28-year-old woman presented with shortness of breath. Complaints accompanied by difficulty swallowing and speaking. The patient had a child who died due to similar symptoms. Signs of airway obstruction are found as inspiratory stridor and suprasternal retraction, pseudomembranes in the pharynx, and subcutaneous crepitation in the colli. Diphtheria infection was confirmed through a throat swab examination with Neisser staining and culture. In addition to isolation, the patients were administered oxygen therapy, anti-diphtheria toxin, penicillin procaine, dexamethasone, and additional supportive therapy. Diphtheria infection is transmitted through direct contact, droplets or contaminated items. Manifestations of laryngeal diphtheria generally come from the extension of tonsillar-pharyngeal diphtheria symptoms, including sore throat, hoarseness, and advanced respiratory obstruction. A definite diagnosis is made by isolating the bacteria or finding an increase in serum antibodies. Therapies targeting infectious conditions and supporting obstetrics help improve the overall patient condition. Diphtheria is a highly contagious and potentially fatal disease, especially for pregnant women; thus, immediate diagnosis is needed. Isolation and appropriate management alleviate upper airway obstruction. Diphtheria management should include both curative therapy and preventive to protect the community further and prevent outbreaks from emerging.
Laporan Kasus: Manajemen Skizofrenia pada Kehamilan: Tan-tangan, Strategi, dan Hasil : Laporan Kasus: Manajemen Skizofrenia pada Kehamilan: Tantangan, Strategi, dan Hasil Cholili, Muhamad Nofa; Nooryanto, Mukhammad
Jurnal Klinik dan Riset Kesehatan Vol 4 No 3 (2025): Volume 4 No 3, Juni 2025
Publisher : RSUD Dr. Saiful Anwar Province of East Java

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.11594/jk-risk.04.3.9

Abstract

Pendahuluan: Skizofrenia adalah gangguan mental serius yang menimbulkan tantangan besar bagi individu selama kehamilan. Kondisi ini memerlukan pemantauan dan manajemen yang cermat untuk kesejahteraan ibu dan janin yang dikandung. Abstrak ini bertujuan untuk memberikan gambaran singkat tentang efektivitas dan pertimbangan seputar skizofrenia dalam konteks kehamilan. Tujuan: Menyoroti kompleksitas serta tantangan yang dihadapi oleh individu hamil yang menderita skizofrenia. Kami juga bertujuan untuk mengidentifikasi perlunya manajemen yang disesuaikan dan pendekatan multidisiplin dalam merawat populasi ini, dengan harapan dapat meningkatkan hasil dan kualitas hidup bagi ibu dan bayinya. Metode: Pendekatan metodologi yang digunakan dalam penulisan abstrak ini adalah analisis literatur dari berbagai sumber yang relevan. Kami menyusun informasi tentang pentingnya skizofrenia pada kehamilan, manajemen yang disarankan, serta hasil-hasil penelitian terkini di bidang ini. Hasil: Individu hamil dengan skizofrenia sering menghadapi gejala yang memburuk, memerlukan pemantauan ketat, dan intervensi yang disesuaikan. Penggunaan obat antipsikotik perlu dievaluasi dengan cermat terhadap risiko dan manfaatnya bagi ibu dan janin. Kolaborasi multidisiplin antara berbagai bidang kesehatan menjadi kunci dalam menangani kebutuhan yang kompleks dari populasi ini. Kesimpulan: Abstrak ini menekankan pentingnya perawatan prenatal yang komprehensif dan kolaborasi multidisiplin dalam menangani skizofrenia selama kehamilan. Meskipun tantangan yang dihadapi, individu dengan skizofrenia dapat mengalami kehamilan dan kehamilan dengan dukungan yang tepat. Namun, penelitian lebih lanjut diperlukan untuk meningkatkan pemahaman dan perawatan bagi populasi yang rentan ini. Abstrak ini diharapkan dapat menjadi kerangka dasar dalam upaya meningkatkan hasil dan kualitas hidup bagi individu yang terkena dampak skizofrenia selama kehamilan. Kata Kunci: Skizofrenia; kehamilan; antipsikotik; kolaborasi; penelitian.
Hemangioma pada Anak: Literatur Review Arviansyah, Arviansyah; Wihastyoko, Herman; Agustina, Wilma; Siswanto, Yudi; Sintaningrum, Elisabeth
Jurnal Klinik dan Riset Kesehatan Vol 4 No 1 (2024): Edisi Oktober
Publisher : RSUD Dr. Saiful Anwar Province of East Java

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.11594/jk-risk.04.1.5

Abstract

Hemangioma is a vascular anomaly that is benign and generally occurs in children. ISVVA 2018 classifies vascular anomalies into two categories, namely vascular malformations and vascular tumors (hemangioma). The prevalence of hemangioma is higher in low birth weight babies, premature babies, and girls. Several theories suggest that hemangiomas are caused by vasculogenesis and angiogenesis or an imbalance between angiogenic and antiangiogenic factors. Hemangiomas grow through a proliferation phase, involution phase, and post-involution phase. Hemangioma classification is based on the depth of the lesion, time of appearance of the lesion, distribution of the lesion, and its relationship to syndrome complication.. Diagnosis of hemangioma is based on anamnesis, physical examination, and supporting examinations which include USG, MRI, and CT-Scan. Hemangiomas that lead to complications should require immediate treatment. Hemangioma treatment can be done with topical therapy, systemic therapy (propranolol, corticosteroids, β-blockers, vincristine, rapamycin), laser therapy (PDL, diode, Nd: YAG, argon, KTP, CO2, IPL), and other treatments consisting of from surgical and non-surgical procedures (bleomycin injection).
Analisis Faktor yang Mempengaruhi Peningkatan Serum Transaminase pada Pasien Demam Dengue di RSUD Ngudi Waluyo Wlingi pada Tahun 2023-2024 Wijayanto, Fajar; Insanitaqwa, Aleyda
Jurnal Klinik dan Riset Kesehatan Vol 3 No 3 (2024): Edisi Juni
Publisher : RSUD Dr. Saiful Anwar Province of East Java

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.11594/jk-risk.03.3.4

Abstract

Background: Dengue fever has become a global and national health concern due to its increasing incidence rate over the past six years. Dengue infection may present with variable sign and symptoms. Major organ involvement may occur, including liver, which is characterized by an elevated transaminase serum level. Aim: This study aims to identify factors contributing to increased transaminase serum levels in patients with dengue fever at Ngudi Waluyo Wlingi General Hospital between 2023-2024. Methods: One hundred and sixty-nine patients with positive dengue serology admitted to Ngudi Waluyo Wlingi General Hospital from January 1st, 2023 to May 19th, 2024, were reviewed retrospectively. Only patients aged 15 years and over with complete laboratory data were included in this retrospective cross-sectional study, using total sampling approach. We collected demographic and laboratory data from electronic medical records, then analyzed and correlated the data with liver function values. Results: Increased AST levels was observed in 70 patients (41.4%), while ALT values was elevated in 32 patients (24.9%). This increase was significantly linked to decreased platelet counts (p=0). Additionally, age was statistically associated with ALT levels (p=0.022), while gender was significantly related to AST levels (p=0.04). However, leukocyte levels and dengue serology showed no significant correlation with serum transaminase levels (p>0.05). Together, dengue serology, platelet counts, leukocyte levels, gender, and age collectively have a significant effect on AST (14.3%) and ALT (13.6%) values. Among these factors, platelet counts exerted the greatest influence on AST and ALT levels. Conclusion: Elevated transaminase serum levels may occur in patients with dengue fever. This is associated with platelet counts, age, and gender. Therefore, diagnosing dengue infection should prompt measurement of liver function to ensure appropriate management according to each patient’s condition.
Penyakit Menular vs Penyakit Tidak Menular Djajalaksana, Susanthy
Jurnal Klinik dan Riset Kesehatan Vol 3 No 3 (2024): Edisi Juni
Publisher : RSUD Dr. Saiful Anwar Province of East Java

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.11594/jk-risk.03.3.1

Abstract

Pengaruh Latihan Fisik terhadap Kadar Marker Inflamasi pada Pasien Hipertensi Pulmonal Aziz, Indra Jabbar; Martini, Heny
Jurnal Klinik dan Riset Kesehatan Vol 4 No 1 (2024): Edisi Oktober
Publisher : RSUD Dr. Saiful Anwar Province of East Java

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.11594/jk-risk.04.1.7

Abstract

Pulmonary hypertension (PH) is characterized by pulmonary vascular dysfunction, which can lead to right heart failure and death, as well as the accumulation of inflammatory cells in the perivascular area. Chronic inflammation plays an important role in the pathophysiology of pulmonary hypertension. Inflammatory markers such as C-reactive protein (CRP), interleukin-6 (IL-6), and tumor necrosis factor-alpha (TNF-α) are often elevated in patients with pulmonary hypertension. The accumulation of inflammatory cells accelerates the remodeling process of pulmonary blood vessels and pulmonary hypertension. Despite the current therapeutic approaches for pulmonary hypertension (PH), which aim to improve functional capacity and hemodynamics, pulmonary hypertension remains incurable but remains controllable. Inflammatory processes play a critical role in progressive pulmonary hypertension. Physical exercise can reduce the risk of chronic disease, and recent research has shown that it improves inflammatory marker profiles. This literature review aims to combine evidence on the influence of physical exercise on levels of inflammatory markers in patients with pulmonary hypertension.
Hubungan Kadar Trombosit dengan Gambaran Luas Lesi Tuberkulosis Paru melalui Foto Chest X-Ray Alimsjah, Yohanes Audric; Yueniwati, Yuyun; Nugroho, Rafiq Sulistyo
Jurnal Klinik dan Riset Kesehatan Vol 4 No 2 (2025): Edisi Februari
Publisher : RSUD Dr. Saiful Anwar Province of East Java

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.11594/jk-risk.04.2.4

Abstract

Background: Pulmonary tuberculosis (TB) is a chronic inflammatory disease accompanied by changes in particular haematological parameters within the blood. The changes in the composition of blood cells can be potential biomarkers to assist tuberculosis diagnosis beside using clinical, microbiological, and radiological tools. Platelets play a vital part in chronic inflammation since they contain different sorts of mediators that are involved in lung damage which is reflected in the extent of lesions on radiological examination. Aim: The research aims to compare the platelets level between minimal/moderate versus extensive lesions in the patient with TB. Methods: The research was a retrospective, cross-sectional study of patients with pulmonary tuberculosis who were treated at Saiful Anwar Hospital from January 2022 to December 2023. The results of the research were analyzed using the Chi-Square method. Results: Patients with extensive pulmonary TB lesions have platelet levels that tend to be high, in contrast to patients with minimal/moderate pulmonary TB lesions tend to have low platelet levels. Conclusion: There was a significant relationship between platelet levels and the extent of pulmonary tuberculosis lesions.
Sebuah Laporan Kasus Penurunan Fungsi Sistolik Ventrikel Kiri pada Pasien Hamil dengan Tetralogy of Fallot yang Telah Dikoreksi : Kardiomiopati Peripartum atau yang Lainnya? Gultom, Yosafat Hasiholan Marthin; Martini, Heny
Jurnal Klinik dan Riset Kesehatan Vol 5 No 1 (2025): Edisi Oktober 2025
Publisher : RSUD Dr. Saiful Anwar Province of East Java

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.11594/jk-risk.05.1.8

Abstract

Background : Tetralogy of fallot (TOF) is the most common cyanotic congenital heart disease (CHD) worldwide. It is estimated that TOF occupies 5 to 8% of total CHD and twice as many among other CHD simple defect. By far, TOF can only be managed by surgical correction. In most cases, post corrected TOF patients may tolerate pregnancy well. The majority of post corrected TOF patients also have good LV function and just about 23% of them have moderate LV dysfunction. Meanwhile, peripartum cardiomyopathy is one of the cause of LV systolic dysfunction in pregnancy. Case Presentation : A 31-years-old 33 weeks pregnant woman was reffered with chief complain of shortness of breath since 1 month before and preceded with bilateral leg edema (NYHA functional class III). Patient with history of  TOF and was corrected surgically with residual tricuspid regurgitation. Patient with normal left ventricle (LV) systolic function by echocardiography at the second semester of pregnancy and deteriorated at the third semester of pregnancy. Due to the rapid deterioration of LV systolic function, the pregnancy was decided to be terminated by surgery. Patient was treated with bisoprolol, bromocriptine, captopril and warfarin. During the hospitalisation, patient didn’t develop any of arrhytmia or hemodynamic issue. After the termination, patient was with improvement of shortness of breath (NYHA functional class II) and improvement of LV systolic function. Conclusion : A pregnant, post corrected TOF, woman with rapid deterioration LV systolic function and clinical manifestation of heart failure underwent pregnancy termination by surgery. After the termination, patient still with shortness of breath and improvement of LV systolic function.
Risiko Kardiovaskular pada Terapi Radiasi: Tinjauan Klinis tentang Penyakit Jantung yang Diinduksi oleh Radiasi Widhianto, Andre Tegar
Jurnal Klinik dan Riset Kesehatan Vol 4 No 2 (2025): Edisi Februari
Publisher : RSUD Dr. Saiful Anwar Province of East Java

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.11594/jk-risk.04.2.5

Abstract

Radiotherapy, which has become a pivotal part of cancer treatment over the past 50 years, has indeed proven to increase patient cure rates. However, despite its success, radiotherapy also carries inevitable side effects on the cardiovascular system, specifi­cally radiation-induced heart disease (RIHD). RIHD encompasses a variety of heart diseases, including pericardial disease, coronary artery disease, valvular heart disease, conduction system abnormalities, cardiomyopathy, and vascular disease of medium or large vessels. These side effects can result from the direct impact of radiation on the function and structure of the heart or by accelerating the progression of pre-existing cardiovascular diseases, especially in patients with prior cardiovascular risk factors. Scientists have now developed non-invasive methods to detect RIHD. Additionally, vari­ous efforts are being made to prevent and minimize RIHD. This review delves deeper into the pathogenesis, clinical manifestations, diagnosis, management, and prevention of RIHD.

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