cover
Article Per Year (5 Year)
All
Home Page
OAI Link
Editorial Team
Contact
Reviewer
Google Scholar
Contact Name
Nur Samsu
Contact Email
jkrisk.rssa@gmail.com
Phone
+6285331387234
Journal Mail Official
jkrisk.rssa@gmail.com
Editorial Address
Jurnal Klinik dan Riset Kesehatan (Journal of Clinical and Health Research) Bidang Pendidikan dan Penelitian, RSUD dr. Saiful Anwar Malang Jl. Jaksa Agung No. 2, Kec. Klojen, Malang 65112 Phone/Fax: 0341 – 362101 / 0341 - 369384 Email: jkrisk.rssa@gmail.com
Location
Kota malang,
Jawa timur
INDONESIA
Jurnal Klinik dan Riset Kesehatan
Published by RSUD Dr. Saiful Anwar Malang
ISSN : 28092678     EISSN : 28090039     DOI : https://doi.org/10.11594/jk-risk
Core Subject : Health, Science,
Biochemistry, Genetics & Molecular Biology Health Professions Medicine & Pharmacology Nursing Public Health
Jurnal Klinik dan Riset Kesehatan (JK-RISK) – RSUD dr. Saiful Anwar Malang adalah jurnal open-access resmi yang dikelola oleh tim Penelitian dan Pendidikan Rumah Sakit Umum Daerah dr. Saiful Anwar Malang, Jawa Timur, Indonesia. JK-RISK menerbitkan satu volume yang terdiri atas tiga nomor setiap tahunnya yang diterbitkan pada bulan Oktober, Februari, dan Juni. JK-RISK hanya akan menerbitkan jurnal berbahasa Indonesia. Jurnal Klinik dan Riset Kesehatan – RSUD dr. Saiful Anwar Malang menerbitkan tulisan-tulisan ilmiah hasil penelitian, laporan kasus, tinjauan pustaka dalam bidang kedokteran dan kesehatan yang belum pernah diterbikan di jurnal manapun. Pernyataan kode etik publikasi JK-RISK merupakan pernyataan kode etik yang melibatkan pengelola jurnal, editor, mitra bestari serta penulis dalam proses publikasi jurnal ilmiah. Pernyataan kode etik didasarkan pada Peraturan Kepala LIPI Nomor 5 tahun 2014 tentang Kode Etik Publikasi Ilmiah yang menjunjung tinggi tiga nilai etik dalam publikasi, yaitu (i) Kenetralan, yang berarti terbebas dari pertentangan kepentingan dalam pengelolaan publikasi jurnal; (ii) Keadilan, dengan memberikan kebebasan hak kepengarangan kepada pengarang/penulis; dan (iii) Kejujuran, yang berarti bebas dari duplikasi, fabrikasi, falsifikasi dan plagiarisme (DF2P) dalam publikasi.
Arjuna Subject : Kedokteran - Kedokteran (Lain-Lain)
Articles 200 Documents
 16   17   18   19   20 
Pengaruh Jintan Hitam (Nigella sativa) terhadap Kadar Hypoxia-Inducible Factor (HIF-1), Vascular Endothelial Growth Factor (VEGF), Haemoglobin (Hb), dan Neutrophil-Lymphocyte Ratio (NLR) pada Pasien Kanker Paru Asyari, Claudia Herda; Pratiwi, Suryanti; Chozin, Iin; Izzati, Arina
Jurnal Klinik dan Riset Kesehatan Vol 4 No 3 (2025): Volume 4 No 3, Juni 2025
Publisher : RSUD Dr. Saiful Anwar Province of East Java

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.11594/jk-risk.04.3.4

Abstract

Pendahuluan: Insidensi dan angka kematian akibat kanker paru terus meningkat, sebagian besar disebabkan oleh keterlambatan dalam proses diagnosis. Beberapa penanda yang berhubungan dengan perkembangan kanker paru meliputi faktor hypoxia-inducible factor (HIF-1), vascular endothelial growth factor (VEGF), haemoglobin (HB) dan neutrophil-lymphocyte ratio (NLR). Tujuan: Tujuan studi ini untuk menganalisis perbedaan kadar HIF-1, VEGF, HB dan NLR terhadap pemberian jintan hitam (Nigella sativa). Metode: Penelitian kuantitatif dengan metode pre and post test control group dengan melibatkan 21 sampel yang terbagi menjadi kelompok perlakuan dan kontrol. Kriteria inklusi subjek berupa berusia >18 tahun, terdiagnosis kanker paru primer stadium IIB, IIIA, IIIB, IVA, dan IVB, serta bersedia mengikuti penelitian dan menandatangani informed consent. Kriteria eksklusi subjek adalah pasien kanker primer di luar organ paru dan terdapat kendala di dalam pengambilan data, yang menimbulkan data tidak lengkap. Semua subjek penelitian diberikan kemoterapi dan pada kelompok perlakuan ditambahkan kapsul jintan hitam 500 mg diberikan secara oral dua kali sehari selama sembilan minggu. HIF-1, VEGF, Hb dan NLR diukur sebelum dan setelah sembilan minngu pemberian kemoterapi. Dilakukan analisis uji-t berpasangan untuk menilai perbedaan HIF-1, VEGF, HB dan NLR antara sebelum dan setelah sembilan minggu pemberian kemoterapi. Hasil: Terdapat perbedaan signifikan pada kadar HIF-1, VEGF, Hb dan NLR diantara kelompok kontrol dan perlakuan setelah 9 minggu dengan berturut-turut nilai p= 0,009; p=0,007; p=0,021 dan nilai p= 0,009. Kesimpulan: Pemberian jintan hitam (Nigella sativa) bermanfaat dalam menurunkan kadar HIF-1, VEGF dan NLR dan meningkatkan kadar Hb pada pasien kanker paru
Profil Tekanan Darah, Kontraksi Rahim, dan Denyut Jantung Janin pada Gravida dengan Terapi Neuroprotektan di RSUD Dr. Saiful Anwar : Profile of Blood Pressure, FHR, and Uterine Contractions Of Gravid Women with MgSO4 Neuroprotectant Therapy at HCU Ranu Grati RSUD Dr. Saiful Anwar Sagita, Rahma Furi; Purwaningsih, Tri; Azizah, Firda; Damayanty, Ayu; Amila, Ruri
Jurnal Klinik dan Riset Kesehatan Vol 4 No 3 (2025): Volume 4 No 3, Juni 2025
Publisher : RSUD Dr. Saiful Anwar Province of East Java

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.11594/jk-risk.04.3.3

Abstract

Background: Neuroprotectants are substances used to protect the nerves of fetuses at risk of premature birth. Administration of MgSO4 as a neuroprotectant is one of the interventions given to gravida at risk of premature birth at Dr. Saiful Anwar Hospital. MgSO4 has a vasodilator side effect that is thought to cause a hypotensive effect. Magnesium also has a relaxing effect on smooth muscles which is expected to have the effect of reducing uterine contractions. It is not yet known how MgSO4 affects fetal heart rate. Aim: This study aims to determine the condition of maternal blood pressure, maternal uterine contractions, and fetal heart rate when MgSO4 is administered at the Ranu Grati HCU, Dr. Saiful Anwar Hospital in 2022-2023. Method: Retrospective descriptive study using secondary data. Data were collected from medical records from January 2022 to December 2023 at the Ranu Grati HCU, Dr. Saiful Anwar Hospital. The subjects in this study were all clinical data of gravida patients who received MgSO4 therapy as a neuroprotectant. Preeclampsia gravida patients who received MgSO4 were included in the exclusion criteria. Results: The study or 36 respondents, showed the average of systolic blood pressure of respondents decreasing up to 6,469 mmHg at 16thof MgSO4 admisnistration, then at the 24th hour of administration, systolic blood pressure increased by 0.3 mmHg. The average of diastolic blood pressure decreased by 4.4723 mmHg which occurred from the 0th hour to the 24th hour. Fetal Heart Rate showed a decrease in DJJ frequency of an average of 5,2x/minute. In uterine contractions, 91.7% of patients did not experience uterine contractions during neuroprotectant administration. Conclusion: Neuroprotectant administration has an insignificant effect on reducing blood pressure, fetal heart rate, and maternal uterine contractions. Keywords: Neuroprotectant; MgSO4
Optimalisasi Hasil pada Ruptur Septal Ventrikel : Strategi Integratif dan Tantangan Modern Rosyidi, Muhammad Azhar; Anjarwani, Setyasih; Yogibuana, Valerinna
Jurnal Klinik dan Riset Kesehatan Vol 5 No 1 (2025): Edisi Oktober 2025
Publisher : RSUD Dr. Saiful Anwar Province of East Java

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.11594/jk-risk.05.1.5

Abstract

Acute Myocardial Infarction (AMI) requires immediate management to prevent serious complications, one of which is Ventricular Septal Rupture (VSR). This complication necessitates a multidisciplinary approach due to the complex interaction between ischemic injury, mechanical stress, and inflammatory processes within the heart. Post-AMI VSR leads to a left-to-right shunt, resulting in hemodynamic changes that affect both cardiac function and systemic circulation. Echocardiography serves as the primary modality for assessing the size and location of the rupture, although other imaging modalities are also employed for a more detailed evaluation of hemodynamic alterations. Initial management of post-AMI VSR focuses on hemodynamic stabilization through medical therapy. However, mechanical circulatory support, such as Intra-Aortic Balloon Pump (IABP) or Extracorporeal Membrane Oxygenation (ECMO), is often required in more severe cases. Surgical closure remains the gold standard of treatment, although the optimal timing for surgery is still debated among experts. As an alternative, transcatheter closure using occluder devices can be employed as acute, subacute, or definitive therapy, depending on the patient's condition. The management of post-AMI VSR involves hemodynamic stabilization and a decision between surgical or transcatheter closure, which must take into account the patient's clinical profile and the expertise of the medical team involved.
Karakteristik Klinis, Keluhan Utama, dan Gambaran Pencitraan MRI pada Pasien Makroadenoma Pituitari di RSUD Dr. Saiful Anwar: Karakteristik Klinis, Keluhan Utama, dan Gambaran Pencitraan MRI pada Pasien Makroadenoma Pituitari di RSUD Dr. Saiful Anwar Saputra, Anggadha; Normahayu, Indrastuti; Bahasa Indonesia, Bahasa Indonesia
Jurnal Klinik dan Riset Kesehatan Vol 5 No 1 (2025): Edisi Oktober 2025
Publisher : RSUD Dr. Saiful Anwar Province of East Java

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.11594/jk-risk.05.1.3

Abstract

ntroduction: Pituitary macroadenomas are benign neoplasms of the pituitary gland that often cause significant mass effects, such as compression of the optic chiasm and cavernous sinus, as well as hormonal disturbances. Studies on the demographic characteristics, chief complaints, and imaging features of pituitary macroadenomas in Indonesia remain limited. This study aims to provide a comprehensive overview of patients with pituitary macroadenomas at Saiful Anwar General Hospital. Objective: This study aims to analyze the demographic distribution, clinical complaints, and MRI imaging characteristics of patients with pituitary macroadenomas. Methods: This retrospective descriptive study involved 23 patients who underwent brain MRI at Saiful Anwar General Hospital between January 2020 and December 2024. Demographic data, chief complaints, and MRI imaging findings were analyzed descriptively. Variables evaluated included age, gender, chief complaints, tumor consistency, and signal intensity on T1- and T2-weighted sequences. Results: Among the 23 patients, 82.6% were female, with a mean age of 46.95 years. The most frequently reported complaint was blurred vision (43.5%), caused by optic chiasm compression. Most tumors were solid (69.6%), with hyperintensity dominance on T2-weighted sequences (78.3%). Suprasellar extension was observed in most patients, involving the optic chiasm and cavernous sinus. Conclusion: Pituitary macroadenomas are more commonly found in middle-aged females, with visual disturbances being the dominant complaint. MRI revealed solid consistency with signal heterogeneity, emphasizing the importance of radiological evaluation for early diagnosis and therapeutic planning. A multidisciplinary approach is essential to improve patient quality of life.
Pendekatan Terkini Dan Masa Depan Pada Penyakit Jantung Koroner Prematur Firdaus, Achmad Jauhar; Satrijo, Budi
Jurnal Klinik dan Riset Kesehatan Vol 5 No 1 (2025): Edisi Oktober 2025
Publisher : RSUD Dr. Saiful Anwar Province of East Java

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.11594/jk-risk.05.1.6

Abstract

Coronary artery disease is one of the most frequent cardiovascular diseases and has consistently ranked as the leading cause of death globally for the past three decades. During that period, trends regarding coronary artery disease in young adults have exhibited a complicated interaction of rising incidence and mortality rates in particular populations. Coronary artery disease encompasses a broad range of symptoms and is particularly concerning when it develops at a young age, typically before 55 years in men and 60 years in women. The disease spectrum varied from asymptomatic conditions to chronic symptoms known as chronic coronary syndrome and acute symptoms known as acute coronary syndrome. Multiple recommendations and consensus have been established concerning the approaches to these spectrums, although there is less discourse on precisely addressing the young population's specific requirements. This extensive analysis offers insights into premature coronary artery disease and the multidimensional approach based on the latest guidelines and the novel approach using the help of artificial intelligence and machine learning, emphasizing early detection and diagnosis across the whole clinical spectrum.
Tindakan Invasif sebagai Pilihan Tatalaksana pada Kasus Trombosis Vena Dalam Kemala, Yuke Fawziah; Kurnianingsih, Novi
Jurnal Klinik dan Riset Kesehatan Vol 5 No 1 (2025): Edisi Oktober 2025
Publisher : RSUD Dr. Saiful Anwar Province of East Java

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.11594/jk-risk.05.1.7

Abstract

Deep Vein Thrombosis (DVT) refers to thrombus formation in the deep vein, usually legs, which causes inflammation, and potentially causing disruption of blood flow. Anatomically, DVT is classified as upper and lower extremity DVT. A study in the USA reported 375,000–425,000 new cases of VTE diagnosed per year, of which 50/100,000 cases were DVT. Pathophysiology of DVT is closely related to the Triad of Virchow, i.e. hypercoagulability, stasis and endothelial injury. Establishing DVT diagnosis comprises finding clinical presentation or calculating probability pre-test score, obtaining laboratory examinations, such as D-dimer and imaging test. Venous ultrasound is the gold standard for highly-suspected DVT, while the others are Computed Tomography Venography (CTV) and Magnetic Resonance Venography (MRV). The aim of DVT management based on onset, because immediate treatment in the acute phase, known to reduce significantly the incidence of recurrence, pulmonary embolism and major bleeding. DVT treatment can be divided into non-invasive (i.e. anticoagulation and stocking compression) and invasive. If there are no thrombolysis contraindications, endovascular techniques, such as CDT; PMT; PCDT; venous stenting; as well as IVC/SVC filter placement are recommended. Meanwhile, surgical techniques (i.e. surgical thrombectomy; surgical decompression and vein bypass) are an option if conservative management is unsuccessful, high-risked of life-threatening pulmonary embolism with a low-risk of bleeding, or has severe PTS. By knowing the diagnostic techniques and indications of invasive treatments, it is prospected to plan the appropriate management for each patient, so that increases the successful rate as well as reduce intrahospital and long-term complications.
Analisis Activated Clotting Time pada Intervensi Koroner Perkutan Elektif dengan Heparin Bolus dan Kontinu di RSUD Dr. Saiful Anwar Malang Suprapta, Aloysius; Widito, Sasmojo
Jurnal Klinik dan Riset Kesehatan Vol 5 No 1 (2025): Edisi Oktober 2025
Publisher : RSUD Dr. Saiful Anwar Province of East Java

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.11594/jk-risk.05.1.4

Abstract

BACKGROUND: Unfractionated heparin effectively prevents thrombosis during percutaneous coronary intervention (IKP). Analysis between sex, age, BMI, diabetes, smoking, CHF, hypertension, stroke, lesion characteristics, CHA2DS2-VASc score, platelet, eGFR, and bleeding events with activated clotting time (ACT) achievement aims to elucidate the correlation in elective IKP procedures using heparin bolus administration followed by continuous heparin. OBJECTIVE: To evaluate the relationship of sex, age, BMI, diabetes, smoking, CHF, hypertension, stroke, lesion characteristics, CHA2DS2-VASc score, platelet, eGFR, and bleeding events on achieving an ACT of ≥300 seconds in elective IKP patients at RSSA. METHODS: This observational study analysed medical records of elective IKP patients at RSSA from July 2022 to August 2024. Data were collected via consecutive sampling. Univariate analysis described sample characteristics, while bivariate analysis assessed variable relationships. Logistic regression was used to develop a predictive model if significant variables was found. RESULTS: Among 43 samples, 34.8% achieved ACT ≥300 seconds. No significant relationship was found among sex, age, BMI, diabetes, smoking, CHF, hypertension, stroke, lesion characteristics, CHA2DS2-VASc score, platelet, and eGFR (p=0.078; p=0.936; p=0.264; p=0.139; p=0.063; p=0.535; p=0.64; p=0.324; p=0.349: p=0.885; p=0.677; p=0.15 respectively). There is no bleeding event after procedure. CONCLUSION: There is no relationship between variables sex, age, BMI, diabetes, smoking, CHF, hypertension, stroke, lesion characteristics, CHA2DS2-VASc score, platelet, and eGFR to ACT achievement in elective IKP patients receiving bolus and continuous heparin. Further research with larger sample sizes and standardized ACT measurements is recommended.
Masa Depan Manajemen Penyakit Kronis Transformasi Tren Baru dari Diagnosis hingga Rehabilitasi Fatma, Siti
Jurnal Klinik dan Riset Kesehatan Vol 4 No 2 (2025): Edisi Februari
Publisher : RSUD Dr. Saiful Anwar Province of East Java

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.11594/jk-risk.04.2.1

Abstract

Wujudkan Generasi Bebas Rokok Djajalaksana, Susanthy
Jurnal Klinik dan Riset Kesehatan Vol 4 No 3 (2025): Volume 4 No 3, Juni 2025
Publisher : RSUD Dr. Saiful Anwar Province of East Java

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.11594/jk-risk.04.3.1

Abstract

Heparin: Indikasi Klinis dan Strategi Pencegahan Risiko Perdarahan Samsu, Nur
Jurnal Klinik dan Riset Kesehatan Vol 5 No 1 (2025): Edisi Oktober 2025
Publisher : RSUD Dr. Saiful Anwar Province of East Java

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.11594/jk-risk.05.1.1

Abstract

Page 20 of 20 | Total Record : 200

 16   17   18   19   20 

Filter by Year

2021 2025


Reset
Filter By Issues
All Issue Vol 4 No 3 (2025): Volume 4 No 3, Juni 2025 Vol 5 No 1 (2025): Edisi Oktober 2025 Vol 4 No 2 (2025): Edisi Februari Vol 4 No 1 (2024): Edisi Oktober Vol 3 No 3 (2024): Edisi Juni Vol 3 No 2 (2024): Edisi Februari Vol 2 No 2 (2023): Februari 2023 Vol 3 No 1 (2023): Edisi Oktober Vol 2 No 3 (2023): Edisi Juni Vol 2 No 1 (2022): Edisi Oktober Vol 1 No 3 (2022): Edisi Juni Vol 1 No 2 (2022): Edisi Februari Vol 1 No 1 (2021): Edisi Oktober More Issue