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Jurnal Klinik dan Riset Kesehatan (Journal of Clinical and Health Research) Bidang Pendidikan dan Penelitian, RSUD dr. Saiful Anwar Malang Jl. Jaksa Agung No. 2, Kec. Klojen, Malang 65112 Phone/Fax: 0341 – 362101 / 0341 - 369384 Email: jkrisk.rssa@gmail.com
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Jawa timur
INDONESIA
Jurnal Klinik dan Riset Kesehatan
Published by RSUD Dr. Saiful Anwar Malang
ISSN : 28092678     EISSN : 28090039     DOI : https://doi.org/10.11594/jk-risk
Core Subject : Health, Science,
Biochemistry, Genetics & Molecular Biology Health Professions Medicine & Pharmacology Nursing Public Health
Jurnal Klinik dan Riset Kesehatan (JK-RISK) – RSUD dr. Saiful Anwar Malang adalah jurnal open-access resmi yang dikelola oleh tim Penelitian dan Pendidikan Rumah Sakit Umum Daerah dr. Saiful Anwar Malang, Jawa Timur, Indonesia. JK-RISK menerbitkan satu volume yang terdiri atas tiga nomor setiap tahunnya yang diterbitkan pada bulan Oktober, Februari, dan Juni. JK-RISK hanya akan menerbitkan jurnal berbahasa Indonesia. Jurnal Klinik dan Riset Kesehatan – RSUD dr. Saiful Anwar Malang menerbitkan tulisan-tulisan ilmiah hasil penelitian, laporan kasus, tinjauan pustaka dalam bidang kedokteran dan kesehatan yang belum pernah diterbikan di jurnal manapun. Pernyataan kode etik publikasi JK-RISK merupakan pernyataan kode etik yang melibatkan pengelola jurnal, editor, mitra bestari serta penulis dalam proses publikasi jurnal ilmiah. Pernyataan kode etik didasarkan pada Peraturan Kepala LIPI Nomor 5 tahun 2014 tentang Kode Etik Publikasi Ilmiah yang menjunjung tinggi tiga nilai etik dalam publikasi, yaitu (i) Kenetralan, yang berarti terbebas dari pertentangan kepentingan dalam pengelolaan publikasi jurnal; (ii) Keadilan, dengan memberikan kebebasan hak kepengarangan kepada pengarang/penulis; dan (iii) Kejujuran, yang berarti bebas dari duplikasi, fabrikasi, falsifikasi dan plagiarisme (DF2P) dalam publikasi.
Arjuna Subject : Kedokteran - Kedokteran (Lain-Lain)
Articles 200 Documents
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Analisa Trombositosis, Leukositosis dan Kombinasi Trombositosis- Leukositosis terhadap Hasil RECIST 1.1, Progression Free Survival dan Stadium pada Pasien Karsinoma Paru Bukan Sel Kecil yang mendapatkan Kemoterapi Analisa Trombositosis, Leukositosis dan Kombinasi Trombositosis-Leukositosis terhadap Hasil RECIST 1.1, Progression Free Survival dan Stadium pada Pasien Karsinoma Paru Bukan Sel Kecil yang mendapatkan Kemoterapi Wiyono, Hendri; Setyawan, Ungky Agus; Pratiwi, Suryanti Dwi
Jurnal Klinik dan Riset Kesehatan Vol 5 No 1 (2025): Edisi Oktober 2025
Publisher : RSUD Dr. Saiful Anwar Province of East Java

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.11594/jk-risk.05.1.2

Abstract

Background: Lung cancer is the most common malignancies that lead to highest mortality and morbidity. Advanced lung cancer is treated with chemotherapy and the evaluation is using RECIST. Thrombocytosis and or leukocytosis in lung cancer, theoritically stand with bad condition.The aim of this study is to analyse whether thrombocytosis and or leukocytosis can be a prognostic factor compare to the result of RECIST,Progression Free Survival and the stadium of lung cancer. Method: This study uses retrospective analytic cross-sectional design.Data were taken from medical record at Saiful Anwar Hospital,2018-2021,processed with Chi square,Mann-Whitney, and Fisher Exact test. Result:The result of Chi square Thrombocytosis and Leukocytosis to the first result of RECIST are ᵡ²(1) =59,659; p=0,000 and ᵡ²(1) = 5,707:p=0,017.To the median PFS 5,66 months the test are ᵡ²(1)=51,776:p=0,000; ᵡ²(1)=4,259:p=0,039.To the state of progression, the test are ᵡ² (1)=15,171:p=0,000; ᵡ²(1)=2,226:p=0,329.To stadium, Mann-Whitney test are:1145,00;Z= -1,026:p=0,305 and 1040,500;Z= -1,393:p=0,164. Conclusion: There is statistically significance between thrombocytosis or leukocytosis to the first result of RECIST,median PFS 5,66 months.No significance to the stadium of lung cancer.Thrombocytosis and or leukocytosis can be a prognostic factor for result of chemoteraphy.
Sebuah Penundaan Pemasangan Stent pada Beban Trombosis Tinggi Kurniawan, Catur Rizky; Widito, Sasmojo
Jurnal Klinik dan Riset Kesehatan Vol 4 No 3 (2025): Volume 4 No 3, Juni 2025
Publisher : RSUD Dr. Saiful Anwar Province of East Java

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.11594/jk-risk.04.3.5

Abstract

Deferred stenting is a revascularization strategy that involves two stages of implementation, where stent placement is delayed for a predetermined period after stable coronary blood flow is achieved. This approach aims to reduce the risk of complications such as slow-flow or no-reflow phenomena, particularly in patients with high thrombus burden (HTB). This study seeks to explore the benefits and limitations of deferred stenting in HTB cases, as well as its impact on long-term clinical outcomes. The primary benefits of deferred stenting include significant reduction in thrombus burden, improved myocardial perfusion quality, and decreased risk of complications such as distal embolization and slow-flow phenomena. Research indicates that this technique can enhance left ventricular ejection fraction (LVEF) and reduce infarct size. However, deferred stenting also carries potential complications, including the risk of re-occlusion, need for unplanned revascularization, and increased bleeding risk due to prolonged use of parenteral anticoagulants. Evaluation of various studies reveals inconsistent results regarding the effectiveness of deferred stenting. Some studies report significant benefits in reducing thrombus burden and improving clinical outcomes, while others highlight a higher risk of complications without meaningful short-term improvements. The CRUSADE score is used to assess bleeding risk in HTB patients, with scores >20 indicating a high bleeding risk and contraindicating the use of GPIIb/IIIa inhibitors. Overall, deferred stenting offers potential benefits in HTB cases, its implementation should be carefully considered due to associated risks and additional costs. Further research is needed to determine the optimal protocols and assess the long-term benefits of this technique.
Infark Miokard Akut Tanpa Elevasi Segmen ST pada Wanita Usia Muda dengan Ketoasidosis Diabetik Rahmawati, Novi; Prasetya, Indra; Prastya, Andhika
Jurnal Klinik dan Riset Kesehatan Vol 4 No 3 (2025): Volume 4 No 3, Juni 2025
Publisher : RSUD Dr. Saiful Anwar Province of East Java

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.11594/jk-risk.04.3.8

Abstract

Diabetic ketoacidosis (DKA) is the primary acute metabolic complication of diabetes mellitus (DM), specifically type 2 DM. Individuals with acute coronary syndrome (ACS) have a twice-higher incidence compared to non-diabetic individuals. In people with DM, ACS is responsible for 75% of mortality. This case report investigates a 34-year-old female patient who presented at the Emergency Department of Saiful Anwar Malang Hospital with acute gastrointestinal symptoms of diarrhea and moderate to severe dehydration. Patients with a history of type 2 DM were first diagnosed at the age of 28. The laboratory tests indicated the presence of high blood sugar levels, metabolic acidosis, and ketone-positive. During DKA hydration management, patients have atypical angina with ECG changes from sinus tachycardia to episodic Total AV Block (TAVB) spontaneous termination, increased cardiac enzyme HS (high-sensitivity) Troponin I. Patients diagnosed with acute Non-elevated Segment ST Myocardial Infarction (NSTEMI) very high risk criteria. The patient performed an immediate invasive strategy and promptly identified stenosis in three coronary arteries, with the target lesion being in the Right Coronary Artery (RCA). Subsequently, a drug-eluting stent was implanted in the osteal to mid RCA. Efficient and timely management strategies that prioritize accuracy and simultaneous therapy for cases of DKA and NSTEMI to achieve optimal outcomes.
Modalitas Pencitraan Non Invasif pada Sindroma Koroner Kronis Indrihapsari, Pratiwi; Widito, Sasmojo
Jurnal Klinik dan Riset Kesehatan Vol 4 No 2 (2025): Edisi Februari
Publisher : RSUD Dr. Saiful Anwar Province of East Java

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.11594/jk-risk.04.2.7

Abstract

Advancements in non-invasive cardiovascular imaging technology have introduced robust diagnostic modalities for managing cardiovascular diseases. Three prominent techniques in this domain are stress echocardiography, coronary computed tomography angiography (CCTA), cardiac magnetic resonance imaging (CMR), Single Photon Emission Computed Tomography (SPECT), and Positron Emission Tomography (PET). These modalities provide crucial information for accurate diagnosis and optimal therapeutic planning. Stress echocardiography occupies a strategic position in the diagnostic algorithm, particularly in suspected or confirmed cases of coronary artery disease. The strength of this modality lies in its ability to provide a comprehensive picture of myocardial functional status. Meanwhile, CCTA offers superiority in visualizing and characterizing atherosclerotic plaques in coronary vessels, enabling early detection and more precise risk stratification. This literature review aims to explore critical aspects of non-invasive cardiovascular imaging modalities in the context of diagnosing Chronic Coronary Syndrome.
TERAPI HEPARIN TIDAK TERFRAKSI PADA PROSEDUR INTERVENSI KORONER PERKUTAN ELEKTIF saidi, zaki; Widito, Sasmojo
Jurnal Klinik dan Riset Kesehatan Vol 4 No 3 (2025): Volume 4 No 3, Juni 2025
Publisher : RSUD Dr. Saiful Anwar Province of East Java

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.11594/jk-risk.04.3.6

Abstract

Coronary artery Disease (CAD) occurs due to an imbalance between myocardial oxygen demand and supply due to total or partial blockage of the coronary artery. Occlusion of coronary artery blood vessels in CAD patients requires revascularization to restore blood flow and myocardial perfusion. One of the mechanical revascularization efforts is to perform a percutaneous coronary intervention (PCI) procedure. This technique involves the use of a guided catheter directed to the location of the coronary artery blockage, followed by balloon dilation and stent placement to maintain patency. Blood vessel injury during PCI exposes serine proteases to tissue factor and collagen, stimulating procoagulants that will activate the coagulation cascade. In CAD patients undergoing PCI therapy, periprocedural pharmacotherapy is given in the form of antiplatelet therapy accompanied by intravenous anticoagulants such as unfractionated heparin. Unfractionated heparin produces its main anticoagulant effect by inactivating thrombin and activating factor X (factor Xa) through a mechanism dependent on antithrombin (AT). Intravenous administration of unfractionated heparin in addition to producing anticoagulant effects can also increase the risk of bleeding. In order for the drug to effectively prevent clotting and not cause bleeding, it is necessary to determine the right dose. In connection with this, it is necessary to monitor hemostasis function with optimal Activated Clotting Time (ACT) values ​​to prevent the risk of thrombosis and bleeding in patients undergoing PCI.
Hubungan Antara Kepatuhan Terapi Antiretroviral terhadap Terjadinya Kondisi Underweight, Lingkar Betis, Handgrip Strength, dan Skinfold Triceps pada Pasien HIV/AIDS di RSSA Malang Budiarti, Niniek; Kurniawan, Fitto; Soenarti, Sri
Jurnal Klinik dan Riset Kesehatan Vol 4 No 1 (2024): Edisi Oktober
Publisher : RSUD Dr. Saiful Anwar Province of East Java

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.11594/jk-risk.04.1.4

Abstract

Background: Human Immunodeficiency Virus or commonly known as HIV is a virus that infects CD4 cells thereby impaired the human immune system. The number of new HIV cases in Indonesia in 2019 was reported to have reached 50,282 cases and tends to increase from year to year. What often happens in people with HIV/AIDS (PLWHA) tends to experience weight loss accompanied by opportunistic infections that do not occur in normal people. Adherence to therapy is the main factor that must be emphasized by PLWHA in order to achieve treatment success. However, ARV therapy adherence rates are reported to be <80%. This number can be a predictor of therapy failure. One indicator of the success of therapy is when there is clinical improvement in the patient's condition, such as no opportunistic infections or weight gain. Aim: The aim of this study was to determine whether there is a relationship between adherence to antiretroviral therapy and underweight conditions in HIV/AIDS patients. Methods: This study used a cross sectional design with an analytical observational nature and the research subjects were patients at RSSA Malang who visited from June to August 2023. Results: The results of the study showed that there was a significant relationship between adherence to taking ARVs and being underweight (p=0.018) and there was no significant relationship between adherence to taking ARVs with calf circumference, handgrip strength, and triceps skinfold. Conclusion: The conclusion of this study is that the more compliant the patient is with ARV therapy, the higher the increase in body mass index and the smaller the possibility of becoming underweight.
Kewaspadaan terhadap Kejadian Stroke pada Pasien Pasca Bedah Pintas Arteri Koroner saidi, zaki; Widito, Sasmojo
Jurnal Klinik dan Riset Kesehatan Vol 5 No 1 (2025): Edisi Oktober 2025
Publisher : RSUD Dr. Saiful Anwar Province of East Java

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.11594/jk-risk.05.1.9

Abstract

Coronary artery bypass grafting (CABG) is a leading cause of iatrogenic stroke. According to the literature, the incidence of stroke following CABG ranges from 1.1% to 5.7%, with most strokes occurring within the first 48 hours after surgery. The risk of stroke after CABG is associated with a significantly higher mortality rate. A 62-year-old male patient with risk factors including hypertension and diabetes mellitus, as well as coronary artery disease 3 vessel disease left main disease (CAD3VD LM disease), was scheduled for CABG. Preoperative data indicated cardiomegaly on chest X-ray, normal carotid and extremity duplex ultrasonography, and echocardiography revealed a decreased ejection fraction and Regional Wall Motion Abnormality (RWMA). The CABG procedure lasted 7 hours and was performed using an on-pump technique, with cardiopulmonary bypass (CPB) time of 232 minutes and aortic clamp time of 123 minutes. Two days after the CABG, the patient developed complications in the form of an infarct stroke, which was confirmed by CT imaging. The stroke led to a prolonged hospitalization period, totaling 14 days. The mechanism of post-CABG stroke is divided into embolic and hypoperfusion processes, both influenced by various risk factors. In this patient, risk factors such as hypertension, type II Diabetes Mellitus, decreased ejection fraction, and perioperative factors such as prolonged CPB and aortic clamp times, along with aortic manipulation during the on-pump procedure, contributed to the increased risk of stroke.
Akurasi Pemeriksaan Intraoperatif pada Tumor Muskuloskeletal di Instalasi Patologi Anatomi Rumah Sakit Umum Dr. Saiful Anwar Malang periode 2020-2022 Laitupa, Hamka Muhammad Nasir; Norahmawati, Eviana; Dewi, Rose
Jurnal Klinik dan Riset Kesehatan Vol 4 No 3 (2025): Volume 4 No 3, Juni 2025
Publisher : RSUD Dr. Saiful Anwar Province of East Java

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.11594/jk-risk.04.3.2

Abstract

Background: Frozen section and intraoperative cytology examinations for musculoskeletal tumors are quite necessary, mainly to find out whether a representative specimen can be obtained for a definite diagnosis. Apart from that, it can also be done to determine the radicality of the surgery However, intraoperative pathological examination in musculoskeletal tumours cases as a difficult diagnostic interpretation, one of which may be due to the morphological features of some musculoskeletal tumors are being difficult to differentiate. Aim: To determine the diagnostic accuracy of frozen section and histopathological examination of musculoskeletal tumors. Methods: This study uses a retrospective diagnostic test method which presents the accuracy of frozen section examination compared with histopathological examination as the gold standard in musculoskeletal tumors by determining the sensitivity, specificity, ppv, npv. diagnostic accuracy of musculoskeletal tumors in the Anatomical Pathology Laboratory of Dr. Saiful Anwar Hospital Malang Results: The diagnostic accuracy of frozen section and histopathology examination is 96% with a sensitivity value of 93%, specificity 100%, npp 100%, npn 91.6%. The diagnostic accuracy of imprint cytology and histopathology is 93.7% with a sensitivity value of 93%, specificity 100%, npp 100%, npn 83.3%. The accuracy of intraoperative frozen section and cytology examinations may be influenced by the pathologist's experience, sampling techniques, tissue processing preparations, and the characteristics of the tumor cells themselves. Conclusion: Intraoperative pathological examination can primarily be used to ensure adequate specimens to support the diagnosis of muculoskeletal tumors. Keywords: frozen section; musculoskeletal tumor.
Antikoagulan Parenteral Pada Intervensi Koroner Perkutan: Mekanisme Kerja, Monitoring, dan Faktor-Faktor yang Memengaruhi Suprapta, Aloysius; Widito, Sasmojo
Jurnal Klinik dan Riset Kesehatan Vol 4 No 3 (2025): Volume 4 No 3, Juni 2025
Publisher : RSUD Dr. Saiful Anwar Province of East Java

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.11594/jk-risk.04.3.7

Abstract

Background: The increasing number of heart attacks also followed by increases percutaneous coronary intervention (PCI). Coronary heart disease and PCI itself will increase the incidence of thrombosis in the coronary blood vessels. The use of parenteral anticoagulants and antiplatelets is necessary before, during and after PCI. Objective: Appropriate use of anticoagulants will provide expected benefits and avoid side effects such as bleeding. Accurate use of anticoagulants requires understanding the mechanism of action, monitoring drug consentration, and considering factors that influence the mechanism of action of anticoagulants. Discussion: There are three anticoagulants commonly used in Indonesia, namely unfractionated heparin, low molecular weight heparin (LMWH), and fondaparinux. These three anticoagulants affect the coagulation process by inhibiting thrombin formation. The profile of each anticoagulant has unique characteristics with heparin as an anticoagulant that is often used and easily available in health facilities, but has different reactions in each person, therefore requires regular monitoring. LMWH and fondaparinux have a more stable reaction so rarely require monitoring. Conclusion: Parenteral anticoagulants are useful in preventing the occurrence of thrombi before and during PCI procedures. Giving the right dose will reduce the effects of bleeding. Unfractionated heparin is an anticoagulant that often be used and available in health facilities but requires regular monitoring. Several factors can influence the mechanism of action of anticoagulants such as gender, body weight, kidney function, platelet count, smoking, and diabetes.
Apakah Perlu Ada Subspesialis Nefro-Kardiologi? Samsu, Nur
Jurnal Klinik dan Riset Kesehatan Vol 4 No 1 (2024): Edisi Oktober
Publisher : RSUD Dr. Saiful Anwar Province of East Java

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.11594/jk-risk.04.1.1

Abstract

Page 19 of 20 | Total Record : 200

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