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Journal of Endocrinology, Tropical Medicine, and Infectious Disease (JETROMI)
Published by TALENTA PUBLISHER
ISSN : 26860872     EISSN : 26860856     DOI : 10.32734
Core Subject : Health, Science,
Health Professions Immunology & microbiology Medicine & Pharmacology Public Health
Journal of Endocrinology, Tropical Medicine and Infectious Diseases (JETROMI) is an international peer-reviewed journal (February, May, August and November) published by TALENTA Publisher, Universitas Sumatera Utara and managed by Faculty of Medicine, Universitas Sumatera Utara. It is dedicated to interchange for the articles of high quality research in the field of Medical Science. The journal publishes state-of-art papers in fundamental theory, case report, experiments and simulation, as well as applications, with a systematic proposed method, sufficient review on previous works, expanded discussion and concise conclusion. As our commitment to the advancement of science and technology, the JETROMI follows the open access policy that allows the published articles freely available online without any subscription. Each publication contains 6 (six) research articles which will be published online.
Arjuna Subject : Kedokteran - Endokrinologi, Diabetes dan Metabolisme
Articles 145 Documents
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Osteogenesis Imperfecta : A Case Report Hastopraja, Ressy; Nasution, Melati Silvanni
Journal of Endocrinology, Tropical Medicine, and Infectious Disease (JETROMI) Vol. 4 No. 2 (2022): Journal of Endocrinology, Tropical Medicine, and Infectious Disease (JETROMI)
Publisher : TALENTA Publisher, Universitas Sumatera Utara

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32734/jetromi.v4i2.8915

Abstract

ABSTRACT Background: Osteogenesis imperfecta (OI) comprises a heterogeneous group of diseases characterized by susceptibility to bone fractures with variable severity and, in most cases, with presumed or proven defects in collagen type I biosynthesis and an estimated prevalence of 1/15,000 births. Management is multidisciplinary involving mainly surgery, physiotherapy, and rehabilitation Case Presentation: A young woman the age of 19 years old came to the Endocrine Polyclinic of H. Adam Malik Hospital, with a complaint of a fracture of the arm and left thigh for 4 years due to a slip. Since a small age, there was difficulty walking due to the twisted bones of the limbs, and surgery was performed. The conclusion of X-ray of right and left femur bones according to the description of osteogenesis imperfecta accompanied by a picture of fracture and osteomalasia and the conclusion of the whole body scan: pathological picture in the bones can be caused by osteogenesis imperfecta. Conclusion: A young woman the age of 19 years old has been reported may have OI type 1, management is multidisciplinary involving mainly surgery, physiotherapy, and rehabilitation.
Association Between Blood Glucose Profiles with Severity of Covid-19 and Type 2 Diabetes Mellitus Patients Ginting, Priska Krinanta; Santi Syafril
Journal of Endocrinology, Tropical Medicine, and Infectious Disease (JETROMI) Vol. 4 No. 2 (2022): Journal of Endocrinology, Tropical Medicine, and Infectious Disease (JETROMI)
Publisher : TALENTA Publisher, Universitas Sumatera Utara

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32734/jetromi.v4i2.9028

Abstract

Background: Individuals with diabetes mellitus (DM), hypertension, and severe obesity (BMI > 40 kg/m2) are more likely to be infected and are at a higher risk for complications and death from COVID-19. The purpose of the study was to evaluate association of Covid-19 severity with blood glucose profile in type 2 diabetes mellitus patients. Method: The study was conducted from June 2021 – September 2021 in the isolation inpatient room of RSUP. H. Adam Malik Medan, and the research samples were all newly patients diagnosed COVID-19 with T2DM comorbidity. The inclusion criteria were all patients aged ≥18 years, COVID-19 group:moderate, severe, and critical degrees, with comorbid T2DM. HOMA-IR was calculated based on fasting plasma insulin and fasting plasma glucose. Results:. There are significant differences in fasting insulin levels and insulin resistance (HOMA-IR) based on severity of Covid-19 infection. There are significant differences on fasting plasma insulin and HOMA-IR between medium degree vs critical degree, and severe degree vs critical degree (p < 0.01). Conclusion: There are significant association between Covid-19 severity with fasting insulin resistance (HOMA-IR) in type 2 Diabetes Mellitus patients, but there aren’t significant association between Covid-19 severity with fasting plasma glucose, post prandial glucose, or HbA1c.
The Level of Knowledge of the Community About Heart Health in The Covid-19 Pandemic Era Harris Hasan; Raynaldo, Abdul Halim
Journal of Endocrinology, Tropical Medicine, and Infectious Disease (JETROMI) Vol. 4 No. 2 (2022): Journal of Endocrinology, Tropical Medicine, and Infectious Disease (JETROMI)
Publisher : TALENTA Publisher, Universitas Sumatera Utara

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32734/jetromi.v4i2.9126

Abstract

Background: Cardiovascular disease is still a global health problem. Data obtained from the World Health Organization (WHO) states that the death rate from cardiovascular disease (CVD) is 17.7 million people every year and 31% is the cause of all global deaths. The purpose of this study was to determine the level of public knowledge about heart health in the covid-19 pandemic era.  Method: The sampling technique used consecutive sampling, namely subjects who came and met the inclusion criteria were included in the study until the number of samples was met. This study is expected to provide information to the public about heart health and its relationship to the era of the covid-19 pandemic in the community/employees in the USU Medical Faculty Results: In this study, the number of samples was 100 people, the age group > 30 years (62%), while the age group ≤ 30 years (38%). The majority of the sample works as official governments 40 people (40%), had good score predicate, good level of knowledge is Government Employees 20 peoples (20%), health workers (20%), while the level of education is Strata 1.  Conclusion: The level of knowledge of the community about heart health in the Covid-19 pandemic era is good with education level Strata 1 and most of them are Government Employees
Cardiometabolic Profile Screening as an Early Detection of Cardiometabolic Risk Sarastri, Yuke; Raynaldo, Abdul Halim; Ilyas, Kamal Kharrazi; lubis, Dian Anindita
Journal of Endocrinology, Tropical Medicine, and Infectious Disease (JETROMI) Vol. 4 No. 2 (2022): Journal of Endocrinology, Tropical Medicine, and Infectious Disease (JETROMI)
Publisher : TALENTA Publisher, Universitas Sumatera Utara

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32734/jetromi.v4i2.9156

Abstract

Background: Cardiometabolic risk profile is a set of interconnected risk factors, namely abdominal obesity, hypertension, dyslipidemia, hyperglycemia, and hyperinsulinemia, and causes global death. This study was conducted to obtain data on cardiometabolic profiles of people who participated in the Commemoration of World Hypertension Day 2021 at RSUP H Adam Malik Medan Method: This research is a descriptive study with a cross-sectional research design peoples namely by looking at the description of the cardiometabolic profile. The sample is an affordable population that meets the inclusion criteria, people with age >18 years old. Variables of blood pressure, waist circumference, blood sugar levels, and total cholesterol levels are numerical variables. Blood pressure examination is measured using a sphygmomanometer and expressed in mmHg units. The measurement of the abdominal circumference is carried out by examining the size of the abdominal circumference obtained using a tape measure in cm. Blood sugar levels are obtained from the results of measuring blood sugar levels during laboratory examination of blood in mg/dl units. Cholesterol levels are obtained from the results of measuring total cholesterol levels from blood laboratory examinations in mg/dl.  Results: All subjects in this study (n= 100) are 42 men and 58 women with normal waist circumference, and education level strata -1, only 9% of the subjects had high blood sugar levels, and 41% of subjects were classified as central obesity 9% of subjects. Most patients (91%) with normal postprandial glucose and high total cholesterol 66%. Conclusion: In this study, most of the cardiometabolic risks of patients are overweight/obesity and dyslipidemia
Correlation Between Small Dense Low-Density Lipoprotein and Risk Factor Cardiovascular on Obesity
Journal of Endocrinology, Tropical Medicine, and Infectious Disease (JETROMI) Vol. 4 No. 2 (2022): Journal of Endocrinology, Tropical Medicine, and Infectious Disease (JETROMI)
Publisher : TALENTA Publisher, Universitas Sumatera Utara

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32734/jetromi.v4i2.9504

Abstract

Background: Small dense low-density lipoprotein concentration (sdLDLC) subclasses are smaller in volume than other LDL types, they have a greater propensity for endothelial penetration and subsequent atherogenesis. The objectives of the study assessed the relationship between sdLDLC and cardiovascular risk in obesity Method: This cross-sectional study was conducted on obesity. Informed written consent was obtained after explaining the nature of the study to the patients, and ethical clearance was obtained. Body mass index (BMI) was measured using standard methods. Laboratory assessment included venous blood samples in a fasted state for the determination of components of the lipid profile [total cholesterol (TC), HDL-C, and TG], ApoB, and sdLDL. The serum glucose was measured using the glucose oxidase/peroxidase method and the lipid profile by the enzymatic colorimetric method. LDL-C was calculated from the formula of Friedewald. Result: This study included 40 obese patients with a BMI of 33.14±5.00 kg/m2, the age of 41.75± 6.02 years old. There was a significant correlation between sdLDL with age, BMI, FPG, PPG, and TG (p < 0.05). Conclusion: There is a significant between sdLDL with risk factors cardiovascular of profile lipid and profile glucose.
Differences In Glycosylated Hemoglobin To Conventional Cardiovascular Risk Factors In Obesity Dharma Lindarto
Journal of Endocrinology, Tropical Medicine, and Infectious Disease (JETROMI) Vol. 4 No. 3 (2022): Journal of Endocrinology, Tropical Medicine, and Infectious Disease (JETROMI)
Publisher : TALENTA Publisher, Universitas Sumatera Utara

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32734/jetromi.v4i3.9578

Abstract

Background: Glycosylated hemoglobin (HbA1c) has been used as an index for clinical diagnosis of diabetes which is closely related to the complications of cardiovascular. The purpose of the study was to assess the differences in HbA1c against conventional cardiovascular risk in obese patients. Method: This cross-sectional study was conducted on obese patients (BMI > 25). This study included 40 obese patients, whereas those with a history of CVD, thyroid disorders, or currently on lipid-lowering agents were excluded. HbA1c is divided over HbA1c < 5.6  and HbA1c > 5.6 (prediabetes), body mass index (BMI) were measured using standard methods. Laboratory assessment included venous blood samples in a fasted state for the determination of components of the lipid profile [total cholesterol (TC), HDL-C, and TG], HbA1c, homeostatic model assessment for insulin resistant (HOMA-IR) using the formula: insulin x fasting glucose / 405, C-reactive protein (CRP), and adiponectin. Result: 40 obese patients participated in the study with an age of 41.7±6.0 years and a BMI of 33.1±5.0 kg/m2, and a significant correlation between HbA1c and age and HOMA-IR. All cardiovascular risk factors tend to increase but increased significantly at age, and TG (p<0.5). Conclusion: In this study, the average HbA1c was significantly correlated with age and HOMA-IR, and all lipid parameters of HbA1c > 5.6 (prediabetes) tended to be higher than normal obesity.
Correlation Between C-Reactive Protein and Blood Sugar Profile and Lipid Profile in Obesity After Lifestyle Modification for 3 Months Putri, Indah Prasetya; Santi Syafril
Journal of Endocrinology, Tropical Medicine, and Infectious Disease (JETROMI) Vol. 4 No. 2 (2022): Journal of Endocrinology, Tropical Medicine, and Infectious Disease (JETROMI)
Publisher : TALENTA Publisher, Universitas Sumatera Utara

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32734/jetromi.v4i2.9591

Abstract

Background. C-reactive protein (CRP) is a phylogenetically highly conserved plasma protein that participates in the systemic response to inflammation and its plasma concentration increases during inflammatory states. The purpose of the study was to determine the correlation between CRP and blood sugar profile and lipid profile in obesity undergoing lifestyle modification for 3 months. Method. The study was conducted on hospital nurses with BMI >25 (obesity) who were selected voluntarily. Before making lifestyle modifications (diet and physical exercise) for 3 months, patients are given lighting, understanding, and training on lifestyle modifications. Patients were examined for BMI, FPG, PPG, HbA1c, LDL, HDL, and ApoB before and after 3 months of lifestyle modification. Result. Lifestyle modification for 3 months had been performed on 20 patients with a BMI of 30.9±4.15 kg /m2 (obesity). There is a significant correlation between CRP and PPG, HbA1C, LDLC, and ApoB (p < 0.005). Conclusion. There is a significant correlation between CRP and glucose profile and lipid profile on obesity undergoing lifestyle modification for 3 months.
Correlation between Neutrophil to Lymphocyte Ratio (NLR) and D-Dimer In Patients Covid-19 with Diabetes Dharma Lindarto; Ginting, Fransiscus
Journal of Endocrinology, Tropical Medicine, and Infectious Disease (JETROMI) Vol. 5 No. 1 (2023): Journal of Endocrinology, Tropical Medicine, and Infectious Disease (JETROMI)
Publisher : TALENTA Publisher, Universitas Sumatera Utara

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32734/jetromi.v5i1.10318

Abstract

Abstract: Background: The neutrophil to lymphocyte ratio (NLR) has been proposed as an infammatory biomarker. Tujuan penelitian adalah menilai hubungan antara NLR dan D-dimer pada pasien Covid-19 dengan diabetes. Method: This is a retrospective descriptive and analytical study carried out at NLR, blood rutin and D-dimer, FPG, and PPG levels of COVID-19 patients with comorbid in H. Adam Malik Medan, Indonesia, from May 19, 2020, to Juny 08, 2021. The data were collected by cheek list, using electronic medical records. The data included age, gender, medical history, comorbidity with diabetics, and ward and ICU admission. All these cases of COVID-19 have been confirmed in the laboratory by Real-Time Reverse Transcription Polymerase Chain Reaction (RTPCR). Results: There were 163 COVID-19 patients with diabetes consisting FPG 241.65±122.23 mg/dl, PPG 286.01±123.92 mg/dl, and HbA1c 9.49±2.41%. There is a significant correlation between NRL and hemoglobin, white blood cells, platelets, neutrophils, and D-dimers (all, p<0.001*). Conclusion: Diabetes is the commonest comorbidity in COVID-19 patients, and NLR and the others inflammatory assessment have reliable parameters for assessing and evaluating the prognosis of the COVID-19 patients as well as an accurate and practical coagulation parameter for predicting mortality.
Predicting the Risk of Mortality for Patients Diabetic with Coronavirus Disease (COVID-19): A Retrospective study Dharma Lindarto; Ginting, Fransiscus
Journal of Endocrinology, Tropical Medicine, and Infectious Disease (JETROMI) Vol. 5 No. 1 (2023): Journal of Endocrinology, Tropical Medicine, and Infectious Disease (JETROMI)
Publisher : TALENTA Publisher, Universitas Sumatera Utara

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32734/jetromi.v5i1.10319

Abstract

Background. One of the biggest causes of mortality of patients diabetic with COVID-19 in the globe is diabetes mellitus. The study's goal was to examine the predicting the risk of mortality for patients diabetic with coronavirus disease (COVID-19). Methods. This is a retrospective study of patients diabetic with COVID-19 on 22 June 2020 to 21 July 2021 in H. Adam Malik Hospital Medan from 22 June 2020 to 21 July 2021. We collected all the data from electronic medical records on diabetics with SARS-CoV-2 infection, including demographic, clinical, laboratory, and radiological characteristics, treatments, complications, and clinical outcomes. All patients had throat swabs taken from their upper respiratory tracts to determine whether they had SARS-CoV-2 infection. Diagnosis of diabetes mellitus used ADA criteria. Results: There were 163 diabetic patients with COVID-19, consisting of mild (0%), moderate (39.8%), severe (44.2%), and critical (16.5%), and the most comorbid disease is hypertension. There was a significant age difference, length of stay, blood routine, and certain inflammatory markers between patients Diabetic with COVID-19 discharged from the hospital and died (all, p<0.05). The predicted death of patients diabetic with COVID-19 was D-dimer (OR: 4.069; p=0.008*;95% C.I: 1.43-11.55) and dexamethasone use (OR:4.769; p=0.007*; C.I: 1.54-14.71). Conclusion. The use of dexamethasone and the increase of D-dimer values increase mortality predictions in treating diabetic patients with COVID-19 in hospitals. To prevent these harms, the management of inpatients diabetic with COVID-19 must be with good glucose consideration and monitoring.
D-Dimer Levels of COVID-19 patients with Diabetes Mellitus: a Retrospective study Dharma Lindarto; Ginting, Fransiscus
Journal of Endocrinology, Tropical Medicine, and Infectious Disease (JETROMI) Vol. 5 No. 2 (2023): Journal of Endocrinology, Tropical Medicine, and Infectious Disease (JETROMI)
Publisher : TALENTA Publisher, Universitas Sumatera Utara

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32734/jetromi.v5i2.10288

Abstract

Background: Diabetes is the commonest comorbidity in Coronavirus disease 2019 (COVID-19) patients, and D-dimer level assessment has reliable parameters for assessing and evaluating the prognosis of COVID-19 patients with comorbid. This study aims to compare D-dimer,  FPG, and PPG levels between COVID-19 patients with comorbid. Method: We conducted a retrospective descriptive and analytical study carried out at D-dimer, FPG, and PPG levels of COVID-19 patients with comorbid in a tertiary Hospital in Medan, Indonesia, from April 04, 2020, to November 22, 2020. The data were collected by cheek list, using electronic medical records. The data included age, gender, medical history, comorbidity disease inward, and ICU admission. All these cases of COVID-19 have been confirmed in the laboratory by Real-Time Reverse Transcription Polymerase Chain Reaction (RT-PCR). Result: From 323 COVID-19 patients with comorbidities, there are significant differences in D-dimer, FPG, and PPG levels between all groups of COVID-19 patients with the comorbid disease (p<0.05),  and there is a significant difference in D-dimer, FPG, and PPG level between severity of COVID-19 with comorbidities (p<0.005).     Conclusion: There is a significant difference between D-dimer, FPG, and PPG levels in COVID-19 patients with comorbidities in comorbid type and severity of COVID-19.

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