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Journal of Endocrinology, Tropical Medicine, and Infectious Disease (JETROMI)
Published by TALENTA PUBLISHER
ISSN : 26860872     EISSN : 26860856     DOI : 10.32734
Core Subject : Health, Science,
Health Professions Immunology & microbiology Medicine & Pharmacology Public Health
Journal of Endocrinology, Tropical Medicine and Infectious Diseases (JETROMI) is an international peer-reviewed journal (February, May, August and November) published by TALENTA Publisher, Universitas Sumatera Utara and managed by Faculty of Medicine, Universitas Sumatera Utara. It is dedicated to interchange for the articles of high quality research in the field of Medical Science. The journal publishes state-of-art papers in fundamental theory, case report, experiments and simulation, as well as applications, with a systematic proposed method, sufficient review on previous works, expanded discussion and concise conclusion. As our commitment to the advancement of science and technology, the JETROMI follows the open access policy that allows the published articles freely available online without any subscription. Each publication contains 6 (six) research articles which will be published online.
Arjuna Subject : Kedokteran - Endokrinologi, Diabetes dan Metabolisme
Articles 145 Documents
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Association between VEGF–2578 C>A Gene Polymorphism and Lifestyle in H. Pylori Positive Gastritis Patients Sinulingga, Mario Eka Paskah; Ilhamd
Journal of Endocrinology, Tropical Medicine, and Infectious Disease (JETROMI) Vol. 3 No. 2 (2021): Journal of Endocrinology, Tropical Medicine, and Infectious Disease (JETROMI)
Publisher : TALENTA Publisher, Universitas Sumatera Utara

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (740.856 KB) | DOI: 10.32734/jetromi.v3i2.6203

Abstract

Abstract Background: The polymorphisms make the differences in virulence and pathogenicity of H. pylori, which lead to different clinical manifestations after H. pylori infection. The aim research to assess correlation between between VEGF–2578 C>A Gene Polymorphism and life style in H. Pylori (+) Gastritis Patients. Method: The design of this study is a cross sectional study of H. Pylori (+) Gastritis patients, independent variables is gene polymorphism VEGF-2578C>A and dependent variables are life style (age, gender, BMI and alcohol). Infection of H. Pylori detected 14C-UBT or rapid urease test. Examination of gene polymorphism VEGF-2578C>A by performing DNA extraction (Spin Column Method) with reagent: High Pure PCR Template through PCR procedure. Results: From 59 pasien Gastritis H. Pylori (+), there is no correlation between VEGF-2578 C>A gene polymorphism (consisting of CC, CA and AA) with lifestyle (gender, age consists of < 45 years and > 45 years, BMI consists of < 25 kg/m2 and > 25 kg/m2, alcoholic drinkers ) Conclusion: There is no correlation between VEGF–2578 C>A Gene Polymorphism and life style (age, sex, BMI and alcohol drinking) in H. Pylori (+) Gastritis Patients.
The Association between Triglycerides and Glucose (TyG) Index and Parameters of Metabolic Syndrome SN, Sigit Anugerah Putra SN; Dharma Lindarto
Journal of Endocrinology, Tropical Medicine, and Infectious Disease (JETROMI) Vol. 3 No. 2 (2021): Journal of Endocrinology, Tropical Medicine, and Infectious Disease (JETROMI)
Publisher : TALENTA Publisher, Universitas Sumatera Utara

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (656.674 KB) | DOI: 10.32734/jetromi.v3i2.6231

Abstract

Background: The triglyceride and glucose index (TyG index) has become an attractive option due to the highly available and inexpensive biochemical markers for diagnostic of insulin reciatance (IR). The aim of this study was to investigate the association between TyG index and parameters of metabolic syndrome patients. Method: A cross-sectional was conducted in outpatient polyclinics of the Endocrine-Metabolic division of RSUP H Adam Malik Medan. Criteria of Metabolic Syndrome: (i) abdominal obesity: waist circumference of ≥80 cm in women and ≥90 cm in men in Asean, measured at the umbilical level in a standing position; (ii) systolic blood pressure (SBP) of ≥130 mmHg or diastolic blood pressure (DBP) of ≥85 mmHg (or treatment with an antihypertensive medication), measured in all subjects using a validated digital electronic tensiometer in both upper limbs in a seated position after 15 minutes of rest; (iii) triglycerides levels (TG) of ≥150 mg/dL (1.7 mmol/L) or statin/fibrate treatment; HDL-cholesterol levels (HDL-C) of >80 cm in women and >90 cm in men). Result: In this study there were 20 metabolic syndrome patients. From the data, all patients are obese and HbA1c is normal. There is a significant relationship between TyG and HDL-C and TG (r=-0.60; p=0.005** and r=0.88, p= 0.001**, respectively). Conclusion: There is a significant relationship between TyG and HDL-C and TG of metabolic syndrome patients. Keywords: TyG, Metabolic Syndrome Parameters
A 46-year-Oldman with Gynaecomastia and Cirrhosis Hepatis Child Plug A. A case Report Dian Rosa Lubis, Syarifah; Melati Silvani
Journal of Endocrinology, Tropical Medicine, and Infectious Disease (JETROMI) Vol. 3 No. 2 (2021): Journal of Endocrinology, Tropical Medicine, and Infectious Disease (JETROMI)
Publisher : TALENTA Publisher, Universitas Sumatera Utara

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (839.864 KB) | DOI: 10.32734/jetromi.v3i2.6232

Abstract

Background:  Gynecomastia is defined as the presence of excessive breast tissue in males, which can appear unilateral or bilateral. Bilateral prepubertal gynecomastia in the absence of endocrine abnormalities is extremely rare, with only a few cases in literature. Case Presentation: A  46-year-old man  presented with a  2 years history of bilateral breast enlargement and pain. There is heartburn, shrinking testicles,  and  decreased sexual drive. Vital  examination showed  normal. BMI  : 24. 0 kg/m².  Head  dan neck: normal. On the chest both breasts are enlarged as avocados, palpable time around areola, chewy contingency, press pain, galactorrhea  negative. Lung and cast are  normal. In  the abdominal: hepar, lien and renal are not palpable, and ascites are not found. There is an atrophy of testicles.  Previous history of hepatic cirrhosis with Esophageal Varicose Veins caused by Hepatitis B. Laboratory examination  Estradiol 98.71 pg/mL (range: <62), Testosterone: 8.66 ng/mL (range: 3.0-10.6), LH5.53 mlU/mL, FSH 6.49 mlU/mL, Prolactin 5.08 ng/mL; Total T4 5.57 ng/dL , TSH 1.84 μIU/mL. SGOT U/L 53, SGPT 71 U/L,  Hepatitis B (+), HBsAg Reactive S/CO 414.46; HBeAg: Non Reactive, HBV DNA Undetectable and Albumin 3.6 g/dL. Fibroscan:  Cirrhosis Hepatis. Abdominal ultrasound:  Cirrhosis Hepatis. Gastroscopy:  Esophageal Varicose Veins (F1, LI, CB) + Pan Gastropathy. Conclusion: Reportedly A 46-year-old man presented with  gynaecomastia bilateral with  Cirrhosis Hepatis Child Plug A, given conservative treatment with tamoxiphen for 1 month
Correlation Between Carbon Monoxide Level In Exhaled Air and Pulmonary Function On Grill Street-Vendors In Medan City Chen, Jery; Noni Novisari Soeroso; Syamsul Bihar; Lambok Siahaan
Journal of Endocrinology, Tropical Medicine, and Infectious Disease (JETROMI) Vol. 3 No. 3 (2021): Journal of Endocrinology, Tropical Medicine, and Infectious Disease (JETROMI)
Publisher : TALENTA Publisher, Universitas Sumatera Utara

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (553.733 KB) | DOI: 10.32734/jetromi.v3i3.6382

Abstract

Background. Air pollution is the result of household waste responsible for 3.8 million death and 7.7% of all mortality over the world. One air pollutant which tends to increase year by year is carbon monoxide (CO). CO is produced as the result of the imperfect combustion of machines and the combustion of charcoal. The purpose of this study is to assess the correlation between CO level in exhaled air and pulmonary function on grill street-vendors in Medan city. Method: This study is an observational analytic with a cross-sectional approach. The subjects were grill in Medan city who fulfilled certain inclusion and exclusion criteria with the consecutive sampling method. This study data is primary data which is collected using a questionnaire, smokerlyzer, and spirometry. Result: The subjects of this study are 25 grill street-vendors. Most subjects in this study have red (40%) and green (32%) zone in CO exhaled test and as in pulmonary function test, restrictive (56%) and mixed-type (40%) are the most. The Spearman correlation result between CO level in exhaled air and pulmonary function  FEV1 and FVC are not significant (p=0.068 and p=0.251). Conclusion: There is no significant correlation between CO levels in exhaled air and pulmonary function
The Correlation of Giardiasis with Nutritional Status in Primary School Age Children at SD INPRES 104222 and SDN 101828 in Sei Glugur Village, Pancur Batu District Evita Sola Gracia; Adelina Haryani Sinambela
Journal of Endocrinology, Tropical Medicine, and Infectious Disease (JETROMI) Vol. 3 No. 3 (2021): Journal of Endocrinology, Tropical Medicine, and Infectious Disease (JETROMI)
Publisher : TALENTA Publisher, Universitas Sumatera Utara

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (523.927 KB) | DOI: 10.32734/jetromi.v3i3.6393

Abstract

Background. Giardia lamblia is a protozoan that causes an intestinal infection called giardiasis. This infection can cause the process of absorption of nutrients is not optimal. Giardiasis can result in a decrease in nutritional status. The aim of study is to determain the relationship between giardiasis and nutritional status at the age of elementary school children. Method. This is cross-sectional study of 114 students at SD INPRES 104222 and 101828 in Sei Glugur Village in Pancur Batu District. Primary data collection was carried out by anthropometric examination and examination of stool samples using the formol ether concentration technique at the Parasitology Laboratory of the Faculty of Medicine, Universitas Sumatra Utara. Results. From 114 children who met the inclusion criteria, the incidence of Giardia lamblia infection was 7%. Based on the weight  for height index, 8 (7%) people had poor nutritional status, 61 (53.5%) people with underweight nutritional status 27 (23.7%) people with moderate nutrition and 12 (10,5%) people with good nutrition. Overweight by 1 (0.9%) person and obese 5 (4.4%) people. There is no correlation between giardiasis infection with weight for height (p>0.05). Conclusion. The incidence of Giardia lamblia infection was low and there was no correlation between giardiasis with nutritional status in primary school-age children.
Differences of Lower Urinary Tract Symptoms Degree In Benign Prostatic Hyperplasia Patients With and Without Diabetes Mellitus Clarissa, Jeannis; Warli, Syah Mirsya; Dhirajaya Dharma Kadar; Nurfida Khairina Arrasyid
Journal of Endocrinology, Tropical Medicine, and Infectious Disease (JETROMI) Vol. 3 No. 3 (2021): Journal of Endocrinology, Tropical Medicine, and Infectious Disease (JETROMI)
Publisher : TALENTA Publisher, Universitas Sumatera Utara

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (544.383 KB) | DOI: 10.32734/jetromi.v3i3.6415

Abstract

Background. Benign Prostatic Hyperplasia (BPH) is a benign tumor that most often occurs in men. Many risk factors could cause BPH, one of which is diabetes mellitus (DM). Diabetes mellitus (DM) is a metabolic disease, characterized by hyperglycemia. Method. This study was conducted at the Urology Polyclinic of the Universitas  Sumatera Utara Hospital from August to September 2019. A total of 102 patients diagnosed with BPH were registered by cross-sectional study approach. Detailed medical history and physical examination were performed for all patients to diagnose BPH. While the diagnosis of DM was according to patient history or diabetic-medicine use. International Prostate Symptom Score (IPSS) were completed by all patients to obtain a LUTS degree. Result. From a total of 102 patients diagnosed with BPH there were 97 patients were selected. The mean age of patients was 70.43 ± 7.52 year (range 50-88 year) and the total IPSS score was 17.55 ± 6.55. DM patients were more likely to report severe LUTS and the symptom score evaluated with IPSS was significantly higher than in non non-DM group: 21.69 ± 5.41 vs 16.70 ± 6.41 (p=0.005). For the IPSS subscores, the DM group also show higher storage: 8.38 ± 4.57 vs 5.88 ± 3.72 (p = 0.02), voiding: 9.69 ± 2.47 vs 8.14 ± 3.21, (p= 0.039) and post micturition: 3.63 ± 1.26 vs 2.69 ± 1.744, (p= 0.045) symptoms significantly. Conclusion: Benign Prostatic Hyperplasia patients with DM manifested more severe lower urinary tract symptoms. Storage, voiding, post micturition, and urgency symptoms were also greater.
Level of Knowledge and Attitude of Kualanamu International Airport Employee About Basic Life Support Angeline; Ahmad Yafiz Hasby; Meriza Martineta; Ferryan Sofyan
Journal of Endocrinology, Tropical Medicine, and Infectious Disease (JETROMI) Vol. 3 No. 3 (2021): Journal of Endocrinology, Tropical Medicine, and Infectious Disease (JETROMI)
Publisher : TALENTA Publisher, Universitas Sumatera Utara

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (439.816 KB) | DOI: 10.32734/jetromi.v3i3.6457

Abstract

All level of communities should be taught about basic life support especially for workers who related to giving first aid, one of them is the airport. Ideally, everyone knows the basic first aid techniques and takes regular training to ensure that the knowledge stays on. Basic life support is an effort made to maintain the life of someone who is in danger which can get worse or death if it’s not treated quickly. Basic life support in the first hour can reduce up to 85% of mortality.
Effects of Monosodium Glutamate on the Weight Gain of Experimental Rats Pakpahan, Patrick; Edianto, Deri
Journal of Endocrinology, Tropical Medicine, and Infectious Disease (JETROMI) Vol. 3 No. 3 (2021): Journal of Endocrinology, Tropical Medicine, and Infectious Disease (JETROMI)
Publisher : TALENTA Publisher, Universitas Sumatera Utara

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (396.079 KB) | DOI: 10.32734/jetromi.v3i3.6721

Abstract

Background: Obesity, as defined by the WHO is an abnormal fat consolidation or excessive fat deposit. Those excessive fat deposits have been known to be the risk factors for cardiovascular diseases. One such additive is known to improve the taste of the food is Monosodium Glutamate (MSG). The purpose of the study is to determine the effects of MSG on weight gain. Methods: This is a simple experimental design with a pretest-posttest design. The study was conducted in the Animal House laboratories of the Faculty of Mathematics and Natural Sciences Universitas Sumatera Utara between October and November of 2019. The sample in this experiment is male Wistar rats aged 10-11 weeks that will be fed with standard animal feed mixed with MSG. There are 2 groups of rats (each group 16 rats), one group 1 (non-MSG), and group 2 (MSG). The rats were fed with animal feed (ad labium) for 31 days. The feed given every single day will be weighed and documented. The subcutaneous fat was taken from the abdominal and axillary regions. Result. After 31 days of treatment, re-weighing of both groups of animals was carried out. The initial weight, final weight, total weight gain, total fat extracted and total feed consumed was not different significant (p>0,05). Conclusion. The feeding of MSG for 31 days, did not have significant effects on weight gain. A longer time is needed for evaluation of MSG effect on weight gain
Association of Child-Pugh Score with Renal Dysfunction in Liver Cirrhosis Patients Utomo, Edrick; Siregar, Gontar Alamsyah
Journal of Endocrinology, Tropical Medicine, and Infectious Disease (JETROMI) Vol. 3 No. 4 (2021): Journal of Endocrinology, Tropical Medicine, and Infectious Disease (JETROMI)
Publisher : TALENTA Publisher, Universitas Sumatera Utara

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (572.824 KB) | DOI: 10.32734/jetromi.v3i4.6886

Abstract

Background Renal dysfunction remains a common and serious complication in cirrhotic patients and affecting the prognosis of the patient. Early prevention, diagnosis, and treatment are important to avoid any morbidity and mortality caused. This study aims to evaluate the association between the Child-Pugh score and its parameters with renal dysfunction in liver cirrhosis. Method This study was a retrospective cross-sectional by design. This study was conducted at Adam Malik General Hospital with a total sampling of liver cirrhosis inpatients in January 2017-December 2018 periods. Result Total 259 patients were included with data collected from the medical record. The results of statistical analysis with Chi-square and Fisher’s Exact founded an association between Child-Pugh (p=0.003) and ascites (p=0.014) with renal dysfunction in liver cirrhosis patients. Meanwhile, hepatic encephalopathy was not found in an association with p-value=0.144. Mann-Whitney test used to evaluate median differences of albumin, bilirubin and international internalized ratio (INR) in groups of liver cirrhosis with and without renal dysfunction. The results, albumin was found significant differences with p-value=0.017. Bilirubin and INR were found no significant differences (p>0.05). Conclusion It was concluded association found between Child-Pugh score with renal dysfunction in liver cirrhosis patients.
Brown Tumor of Lower Right Limb in Patients With Primary Hyperparathyroidism: A Case Report Iqbal, Muhammad; Syafril, Santi
Journal of Endocrinology, Tropical Medicine, and Infectious Disease (JETROMI) Vol. 3 No. 4 (2021): Journal of Endocrinology, Tropical Medicine, and Infectious Disease (JETROMI)
Publisher : TALENTA Publisher, Universitas Sumatera Utara

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (749.462 KB) | DOI: 10.32734/jetromi.v3i4.6902

Abstract

Background.Brown tumor of Hyperparathyroidism is a metabolic disorder that can affect the entire skeleton and reactive process due to bone resorption caused by primary or secondary hyperparathyroidism (HPT). Brown tumors can occur as solitary or multiple lesions in any bone, most often in the pelvis, ribs, clavicle, mandibula, and extremities. Here, we report the Brown tumor in the lower right limb in patients with primary HPT, and the literature is reviewed. Case presentation. Patients was women 30 years old had married and come with main complains of difficulty walking. This condition has been experienced by patients since diagnosis with lunb of tibia last 8 months and caused pain from hip to lower leg.  On laboratory results, it showed elevated PTH 1.249 (normal 15-65) pg/dL, elevated phosphatase alkali 1156 (normal 40-150) u/dL, elevated Ca 10,8 (n:8,6 -10,3) mg/dL, phosphor 2,1 (3–4,5) mg/dL. Histology examination of tibia lump was a benign lesion of bone (Brown Tumor). Ultrasonography transabdominal result revealed kidney stones with bilateral renal pelvis dilation, nephrolithiasis non-obstructive was found with size 1 cm & left kidney cyst with size 0.6 cm. On Neck USG showed giant cyst lesion on parathyroid glands. Radiologist pelvic examination results showed bone metastasis disease. Head CT Scan examination concluded as suspect metastatic bone. Body bone scans examination showed pathological bone metastatic process. Conclusion. Brown tumor in right lower limb caused by primary HPT

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