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Journal of Endocrinology, Tropical Medicine, and Infectious Disease (JETROMI)

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Published by TALENTA PUBLISHER

ISSN : 26860872 EISSN : 26860856 DOI : 10.32734

Core Subject : Health, Science,

Health Professions Immunology & microbiology Medicine & Pharmacology Public Health

Journal of Endocrinology, Tropical Medicine and Infectious Diseases (JETROMI) is an international peer-reviewed journal (February, May, August and November) published by TALENTA Publisher, Universitas Sumatera Utara and managed by Faculty of Medicine, Universitas Sumatera Utara. It is dedicated to interchange for the articles of high quality research in the field of Medical Science. The journal publishes state-of-art papers in fundamental theory, case report, experiments and simulation, as well as applications, with a systematic proposed method, sufficient review on previous works, expanded discussion and concise conclusion. As our commitment to the advancement of science and technology, the JETROMI follows the open access policy that allows the published articles freely available online without any subscription. Each publication contains 6 (six) research articles which will be published online.

Arjuna Subject : Kedokteran - Endokrinologi, Diabetes dan Metabolisme

Articles 145 Documents

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Immature Platelet Fraction in Thrombocytopenic Patients
Journal of Endocrinology, Tropical Medicine, and Infectious Disease (JETROMI) Vol. 3 No. 4 (2021): Journal of Endocrinology, Tropical Medicine, and Infectious Disease (JETROMI)
Publisher : TALENTA Publisher, Universitas Sumatera Utara

Bone marrow puncture (BMP), is usually performed to identify thrombopoiesis activity and is still the gold standard to determine the etiology of thrombocytopenia. This diagnostic test is invasive hence it may cause discomfort to the patient. One of noninvasive test to determine the etiology of thrombocytopenia is by measuring immature platelet fraction (IPF). IPF is highly correlated to the activity of thrombopoiesis and by understanding the value, clinicians are able to use it in determining whether or not invasive examination is needed and more importantly avoiding unnecessary platelet transfusion. This research was a cross-sectional descriptive observational study aimed to evaluate IPF value in thrombocytopenic inpatients in the Department of Internal Medicine, Haji Adam Malik Hospital Medan. 83 people were recruited, 48 were female (57.83%) and 35 were male (42.16%). IPF values ranged 0,5-59,6% using Sysmex XN-1000 (reference range 1-4,8%). There were 5 (6.02%) low IPF values, 29 (34.93%) normal IPF values and 49 (59.03%) high IPF values. Evaluation of IPF in thrombocytopenic patients is a promising tool to discriminate central from peripheral thrombocytopenia.

Comparison of The Effects of General and Spinal on Apgar Scores of Babies Born Through Caesarean Section in RSUP Haji Adam Malik Medan from 2018 to 2019 Rambe, Aldo Putra; Nasution, Akhyar Hamonangan; Cut Meliza Zainumi; Nova Zairina Lubis
Journal of Endocrinology, Tropical Medicine, and Infectious Disease (JETROMI) Vol. 3 No. 4 (2021): Journal of Endocrinology, Tropical Medicine, and Infectious Disease (JETROMI)
Publisher : TALENTA Publisher, Universitas Sumatera Utara

Background.Â General anesthesia and spinal anesthesia in cesarean section both have advantages and disadvantages. The scoring system of APGAR is a standardized tool that can inform the condition of newborn infants, which might be influenced by gestational age, medication, resuscitation, cardiorespiratory and neurological conditions of the mother. This study aimed to compare the effect of general and spinal anesthesia usage to the APGAR score of newborn infants at Haji Adam Malik General Hospital Medan. Methode. This study uses an observational-analytic design with a cross-sectional approach,Â conducted using secondary data through the medical records of mothers who gave birth through cesarean section and obtained at the Medical Record Installation at the Haji Adam Malik Hospital Medan from 2018 to 2019. Result. In spinal anesthesia, there are 52 samples for a score of 8-10. Whereas in general anesthesia, there are 52 samples to score 8-10. The APGAR score of 1 minute in infants born through cesarean section under spinal anesthesia had an average of 8.63, with general anesthesia of 8.00 (p=0.001). The 5-minute APGAR score in infants born through cesarean section under spinal anesthesia had an average of 9.85, and with general anesthesia of 8.67 (p=1.000). Conclusion: The 1-minute APGAR score for infants using spinal anesthesia showed a statistically better effect than the 1-minute APGAR score for infants using general anesthesia.

Correlation between Lipid Profile and D-dimer of Covid-19 Patients with Type 2 Diabetes Mellitus
Journal of Endocrinology, Tropical Medicine, and Infectious Disease (JETROMI) Vol. 3 No. 4 (2021): Journal of Endocrinology, Tropical Medicine, and Infectious Disease (JETROMI)
Publisher : TALENTA Publisher, Universitas Sumatera Utara

Background. Lipids play a central role in viral infection, as they represent the structural foundations of cellular and viral membranes. The study aimed to examine the relationship between the D-dimer of T2DM patients with the lipid profile parameters of newly diagnosed COVID-19 patients. Method. This study uses secondary data, which is obtained from medical records of H. Adam Malik Medan Hospital between 2020-2021. The population of this study was all inpatients confirmed COVID-19 through RT-PCR SARS-CoV-2 swab examination. Results. There are 163 participants in this study. HbA1c values were high in T2DM patients with Covid-19, while lipid, and D-dimer profile values were still normal. Parameter of HbA1c, lipid and D-dimer profiles between men and women do not differ significantly. D-dimer is not correlated with HbA1c parameters and lipid profiles Conclusion. In this study, HbA1c values were high in T2DM patients with Covid-19, while D-dimer is not correlated with HbA1c parameters and lipid profiles

Correlation between HbA1C and D-dimer in Type 2 Diabetic with COVID-19 Patients Pangaribuan, Jessica Patricia; M. Aron Pase
Journal of Endocrinology, Tropical Medicine, and Infectious Disease (JETROMI) Vol. 3 No. 4 (2021): Journal of Endocrinology, Tropical Medicine, and Infectious Disease (JETROMI)
Publisher : TALENTA Publisher, Universitas Sumatera Utara

Background: Coronavirus disease-19 (COVID-19) is the disease caused by 2019-nCoV/SARS-CoV-2, a novel Î² corona- virus of group 2B . COVID-19 has been reported to be associated with severe condition with type 2 diabetes mellitus (T2DM). D-dimer is a by product of fibrin degradation. It is widely recognized as a biomarker for thromboembolism and as a prognostic marker for critical patients. Methods: This study uses secondary data, which is obtained by looking at the contents of patient medical records at H. Adam Malik Medan Hospital between 2020-2021. The population of this study was all inpatients confirmed COVID-19 through an RT-PCR SARS-CoV-2 swab examination. The study sample was obtained by the total sampling method, where all populations that meet the criteria of inclusion and exclusion are used as research samples. Patients were triaged as per severity on basis of national guidelines: asymptomatic, Mild (respiratory rate < 24/min, SpO2 >94% at room air), moderate (respiratory rate: 24-30/min, SpO2 90-94% at room air) and severe (respiratory rate >30/min SpO2 < 90%), ARDS and septic shock [6]. HbA1c implementation using HPLC methods and D-dimer is measured by ELISA method. Result: There were 163 patients consisting of 92 men and 71 women, the average age was 56.9Â±10.3 years, and HbA1c, FPG and PPG remained uncontrolled. There were no differences in age parameters of blood sugar profiles and D-dimers between men and women. D-dimers are significantly negatively correlated with PPG. Conclusion: Age, blood sugar profile and D-dimer did not differ significantly between men and women, and D-dimer had a correlation significantly with PPG on T2DM with COVID-19 patients. Keywords : D-dimer, T2DM, COVID-19

Knowledge and Attitude of Medan Selayang Citizens Toward Kidney Diseases in Children Viria Milenia; Rosmayanti Syafriani Siregar; Tasrif Hamdi; Ririe Fachrina Malisie
Journal of Endocrinology, Tropical Medicine, and Infectious Disease (JETROMI) Vol. 4 No. 1 (2022): Journal of Endocrinology, Tropical Medicine, and Infectious Disease (JETROMI)
Publisher : TALENTA Publisher, Universitas Sumatera Utara

Background. Renal disease define as groups of heterogenous disease that affect the function and structure of kidney. Children with end-stage renal disease (ESRD) have 30 times mortality rate than children without ESRD. Early signs and symptoms should be recognized and risk factors should be identified early so kidney disease could be prevented and slow the progress towards worse condition. Prevention can be done by parents and society by hindering or eliminating risk factor from children that could cause kidney disease.Â Therefore, societyâ€™s knowledge and attitude towards childrenâ€™s kidney disease need to be carried out, especially parents,which are childâ€™s first point contact with medical staff. Â Objective. To describe the level of knowledge about symptoms, risk factors, treatment and complications of kidney diseases and precautionary attitude of Medan Selayang citizens towards kidney diseases in children. Methods. The research was a descriptive observational study with cross sectional approach. The sampling method used was non-probability sampling with convenient method. Total sample needed in this research is 100 people who were Medan Selayang citizens that brought children to Puskesmas PB II Selayang.This study used questionnaire as research tool. Results : From 100 respondents, 67% knew that children can get kidney disease and 81% agree that some kidney diseases can be prevented. Conclusion. The knowledge of Medan Selayangâ€™s citizens was still lack especially regarding symptoms, risk factors, and complications. The attitude of the citizens was good.Â

The Etiologies of Pediatric Acute Respiratory Distress Syndrome (PARDS) in Patients Treated at The PICU of Haji Adam Malik Hospital Medan in 2017 â€“ 2020 Dea Ayunda; Ririe Fachrina Malisie; Ahmad Yapiz Hasby
Journal of Endocrinology, Tropical Medicine, and Infectious Disease (JETROMI) Vol. 4 No. 1 (2022): Journal of Endocrinology, Tropical Medicine, and Infectious Disease (JETROMI)
Publisher : TALENTA Publisher, Universitas Sumatera Utara

Background. Pediatric Acute Respiratory Distress Syndrome (PARDS) is considered to occur due to direct lung injury and indirect lung injury. The research aims to describe the causes of PARDS in patients treated at the Pediatric Intensive Care Unit (PICU) of Haji Adam Malik Hospital Medan in 2017-2020. Method. This type of research is a retrospective descriptive study with a cross-sectional study design uses secondary data in the form of medical records. The population of this study were all PICU patients aged 1 month â€“ 18 years at Haji Adam Malik Hospital Medan in 2017-2020 using consecutive sampling technique. Results. Of the 100 PICU patients, there were 55 male patients with the most age group was <12 months. The most common mode of ventilation used is 80 invasive mechanical ventilation and duration of ventilation used has a mean value of 17.72 days. A mean value of Length of stay (LOS) patient was 25.47 days. Based on the Oxygenation Index (OI), of the 80 patients with invasive mechanical ventilation, most patients were 57 at risk PARDS, meanwhile, based on Oxygen Saturation Index (OSI) categories, of the 20 patients with non-invasive mechanical ventilation, most patients were 15 at risk PARDS. Most caused by indirect lung injury, namely 51 (51%), direct lung injury 47 (47%), and due to complications of using a ventilator as much as 2 (2%). Conclusion. The most common direct lung injury factor is the primary pulmonary infection, aspiration, trauma, and other factors. The most common indirect lung injury factor is sepsis, then central nervous system (CNS) disorders, postoperatively, and other factors.

The Correlation Between Grade of Non-Alcoholic Fatty Liver Disease and Lipid Profile in Type 2 Diabetes Mellitus Siregar, Hafiz Syaifullah; Brama Ihsan Sazli
Journal of Endocrinology, Tropical Medicine, and Infectious Disease (JETROMI) Vol. 4 No. 1 (2022): Journal of Endocrinology, Tropical Medicine, and Infectious Disease (JETROMI)
Publisher : TALENTA Publisher, Universitas Sumatera Utara

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32734/jetromi.v4i1.8488

Background.Â Non-alcoholic fatty liver disease (NAFLD) is a form of metabolic liver disease in which fat changes (steatosis) are associated with lobular inflammation, hepatocyte injury, polymorphs, or liver fibrosis. The study aimed to assess the relationship between NAFLD grades and lipid profiles in T2DM.Method.Â The design of the study wasÂ cross-sectionalÂ with the dependent variable being the grade of NAFLDÂ and the independent variable being profile lipid. The sample of this study was NAFLD sufferers who met the inclusion criteria and were taken on a consecutive sampling basis. Diagnosis of NAFLD from anamnesis and physical, examination. Laboratory and abdominal ultrasound (Sonata SG 30 Ultrasound). Stages of NAFLD are divided into Degree I, Degree II, and Degree III. Lipid profile examination is carried out using a spectrophotometer tool colorimetric enzymatic method.Result.Â All patients are T2DM, consisting of Grade 1: 32 (40%), Grade II: 29 (36%), and Grade III: 19 (23%) patients. There was a significant difference between TC, TG, and LDL-C (p < 0.01) in the three grades of NAFLD. There is a significant correlation between NAFLD grade with TC and LDL-C (p < 0.05).Conclusion.Â In T2DM, there is a significant correlation between NAFLD grades and TC and LDL-C, and there was a significant difference between TC, TG, and LDL-C in the three grades of NAFLD.

The Effect of Lifestyle Modification on Lipid Profile and Body Weight in Obese Subject Sugama Trisna Ginting; Melati Silvanni Nasution
Journal of Endocrinology, Tropical Medicine, and Infectious Disease (JETROMI) Vol. 4 No. 1 (2022): Journal of Endocrinology, Tropical Medicine, and Infectious Disease (JETROMI)
Publisher : TALENTA Publisher, Universitas Sumatera Utara

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32734/jetromi.v4i1.8567

Background. The lifestyle modification (LSM) programs program addresses diet, exercise, stress management, and nutritional depletion using cognitive-behavioral approaches to improve the causes of chronic disease. The purpose of the study is to evaluate the effect before and after three months of LSM on lipid profile and body weight parameters of obese subjects Method.Â The participants of age 25-50 years recruited through personal contact consisted of 20 obese subjects who appeared to engage in diet and regular exercise (get at least 150 minutes of exercise a week). The types of physical exercise aerobic (walking, swimming, jogging) were included in the study. TheÂ anthropometric measurements andÂ blood sample was taken before and after three months of LSM. Height (m) is measured using a wall-mounted height bar and body weight (kg) is measured using a scale and its value is used in BMI calculations. The serum of profile lipid was determined by enzymatic colorimetric method and sd-LDL examination was performed indirectly in which the ratio of LDL /Apolipoprotein B.Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Result. After 3 months of LSM, there was a significant decrease in serum LDL, ApoB, BMI, WC, and FPG (p < 0.05) in the obese subject. However, no significant difference was observed in TG, HDL, sd-LDL, PPG, and HbA1C (p>0.05).Â Â Â Â Â Â Â Â Â Â Â Â Conclusion. Lifestyle modification of obese subjects for three months can decrease parameters of body weight and profiles lipids, which means it can prevent cardiovascular diseases.

Correlation Between the Ratio TG/HDL-C and Lipid Profile in Nonalcoholic Fatty Liver Disease Patients Siregar, Hafiz Syaifullah; M.Aron Pase
Journal of Endocrinology, Tropical Medicine, and Infectious Disease (JETROMI) Vol. 4 No. 1 (2022): Journal of Endocrinology, Tropical Medicine, and Infectious Disease (JETROMI)
Publisher : TALENTA Publisher, Universitas Sumatera Utara

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32734/jetromi.v4i1.8595

Background:Â Insulin resistance is identified as an impaired biological response to insulin stimulation of target tissues primarily in the liver, muscle, and adipose tissue. The ratio TG/HDL-C has been proposed as a simple marker of insulin resistance. The study aimed to determine the correlation between the ratio TG/HDL-C and lipid profile in nonalcoholic fatty liver disease (NAFLD) patients Method:Â The design of the study wasÂ a cross-sectional studyÂ with the dependent variable Fibrosis Score of NAFLD sufferers who came to H. Adam Malik Medan General Hospital network hospital from July-September 2021. Diagnosis of NAFLD from anamnesis, physical examination, laboratory, and abdominal ultrasound. Lipid profile examination is carried out using a spectrophotometer tool colorimetric enzymatic method, observed include TC, HDL-C, LDL-C, and TG. Results:Â There are 80 NAFLD patients, aged 54.8Â±8.7 years, with uncontrol T2DM, and normal weight. There was a correlation significantly between the ratio TG/HDL-C with TC-C, TG, HDL-C, LDL-C (p<0.001), and no correlation between ratio TG/HDL-C with age, BMI, FPG, PPG, and HbA1c (p>0.05) Conclusion:Â There is a correlation between ratio TG/HDL-C (as a marker of insulin resistance) and lipid profile in NAFLD patients

The Differences of Pepsinogen I and H. Pylori Levels in Patients With Gastric Premalignant Lesion Lubis, Ainun; Siregar, Gontar Alamsyah
Journal of Endocrinology, Tropical Medicine, and Infectious Disease (JETROMI) Vol. 4 No. 1 (2022): Journal of Endocrinology, Tropical Medicine, and Infectious Disease (JETROMI)
Publisher : TALENTA Publisher, Universitas Sumatera Utara

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32734/jetromi.v4i1.8792

Background: Gastric cancer is the fifth most common cancer worldwide, precancerous lesions is triggered by H. pylori infection and any other factors. Recent reports confirmed that serum pepsinogens are a valuable biomarker gastric cancer even before the discovery ofÂ H.Â pylori. Research Methods: This study is a cross-sectional study involving 80 confirmed patients with Gastric Premalignant Lesion at Adam Malik General Hospital, Permata Bunda General Hospital, Medan, on April-November 2018. These two variables is sought using the Mann Whitney test (normality test P < 0,05). H. pylori were diagnosed by positive result of examination of Carbon-14 urea breath test (C-UBT) or Campylobacter-like organism (CLO). Examination of Pepsinogen I measured by Abbott ARCHITECT Pepsinogen I Reagent Kit (Abbott Laboratories Inc., Chicago, IL, USA). Result: Of the 60 participants who confirmed has gastritis premalignant lesion according to the inclusion criteria. From the table of characteristic descriptive, it was found that 48 patients were male (60%) and 32 patients were female (40%). From CLO and 14C-UBT, it was found 35 patients were H. pylori-positive (43,8%) and 45 patients were H. pylori-negative (56,3%). Mean age was 51.03 Â± 10.97 Â years. Mean levels of Pepsinogen IÂ was 44.28 Â± 21.77. From the second table, it was found that 35 (43,8%) patientsÂ with H. pylori-positive has 47.84 mean levels of Pepsinogen I, and 45 (56,3%) patients with H. pylori-negative has 34,79 mean levels of Pepsinogen I. The results of Mann Whitney's correlation analysis found a significant correlation between Pepsinogen (PG) I and H. Pylori in patients with Gastric Premalignant Lesion (p < 0,05). Conclusion : It was found that there was a correlation between Pepsinogen (PG) I levels and H. Pylori in patients with Gastric Premalignant Lesion (p < 0,05).

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Dharma Lindarto

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+6282168842564

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Jalan Dr T Mansur No 9 Padang Bulan, Kecamatan Medan Baru, Kota Medan, Sumatera Utara, Indonesia

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