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Adhar Arifuddin
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Jl. Soekarno Hatta KM.9, Fakultas Kedokteran Universitas Tadulako , Palu, Provinsi Sulawesi Tengah, 94148
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Healthy Tadulako Journal (Jurnal Kesehatan Tadulako)
Published by Universitas Tadulako
ISSN : 24078441     EISSN : 25020749     DOI : https://doi.org/10.22487
Core Subject : Health,
Dentistry Health Professions Medicine & Pharmacology Nursing Public Health
Healthy Tadulako Journal (Jurnal Kesehatan Tadulako) merupakan media komunikasi dan publikasi ilmiah di bidang ilmu kesehatan yang diterbitkan oleh Unit Penjaminan Mutu Fakultas Kedokteran Universitas Tadulako yang. Jurnal ini terbit secara berkala 4 kali dalam setahun (Januari, April, Juli dan Oktober). Jurnal Tadulako Sehat diterbitkan pertama kali pada tahun 2015. Healthy Tadulako Journal (Jurnal Kesehatan Tadulako) menerima dan menerbitkan artikel penelitian, tinjauan pustaka dan laporan kasus di bidang kedokteran dan kesehatan.
Arjuna Subject : Profesi Kesehatan - Profesi Kesehatan (Lain-Lain)
Articles 447 Documents
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Linagliptin for Type 2 Diabetes Mellitus: A Systematic Review of Efficacy, Safety, Combination Therapy, and Use in High Risk Populations Nazwa Rizkillah; Keysha Feiruzyan Rafeufadattis; Nandita Aulia; Verka Apriani; Hadi Sudarjat
Healthy Tadulako Journal (Jurnal Kesehatan Tadulako) Vol. 12 No. 3 (2026)
Publisher : Faculty of Medicine, Universitas Tadulako

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22487/vytnfy72

Abstract

Background: Type 2 diabetes mellitus requires glucose-lowering therapy that balances efficacy and safety, particularly in patients with renal or cardiovascular comorbidities. Linagliptin is a dipeptidyl peptidase-4 inhibitor with predominantly nonrenal elimination. Objectives: To evaluate the efficacy, safety, combination therapy, and clinical use of linagliptin in selected high-risk populations. Methods: PubMed and Google Scholar were searched for primary clinical studies published from 2015 through 19 August 2026. Eleven eligible studies were synthesized according to PRISMA 2020 principles. Risk of bias was assessed using RoB 2, and clinically heterogeneous outcomes were summarized narratively. Results: Linagliptin reduced HbA1c compared with placebo and demonstrated cardiovascular noninferiority in CARMELINA. Compared with glimepiride, glycemic control was broadly comparable, with less hypoglycemia and weight gain. Empagliflozin produced greater glycemic and metabolic improvements than linagliptin when added to premixed insulin, whereas linagliptin reduced HbA1c more effectively than voglibose in hemodialysis patients. Combination benefits and adverse effects varied according to the partner drug. Conclusions: Linagliptin provides modest glucose lowering with a generally low risk of hypoglycemia, although comparative benefits depend on population, comparator, and clinical outcome.
The Relationship Between Family Emotional Support and Quality of Life in the Elderly M Aditya Ramadhan; Hadi Abdillah; Ernawati Hamidah; Tri Utami
Healthy Tadulako Journal (Jurnal Kesehatan Tadulako) Vol. 12 No. 3 (2026)
Publisher : Faculty of Medicine, Universitas Tadulako

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22487/bv28np94

Abstract

Background: Quality of life among older adults is influenced by physical, psychological, social, and environmental conditions, with family emotional support potentially playing an important role. Objective: To determine the association between family emotional support and quality of life among older adults in the working area of Lembursitu Public Health Center. Methods: This quantitative correlational study used a cross sectional design involving 75 older adults selected through purposive sampling. Family emotional support was assessed using the Family Support Scale, while quality of life was measured using the WHOQOL-BREF. Because the 2 × 3 contingency table contained zero and sparse cells, the association was analyzed using the Fisher Freeman Halton exact test, with Cramer's V as the effect-size measure. Results: Poor emotional support was reported by 49 respondents and good support by 26. Quality of life was poor in 45 respondents, moderate in 4, and good in 26. A statistically significant and strong association was observed (p < 0.001; Cramer's V = 1.00). Conclusions: Family emotional support was strongly associated with quality of life among older adults. However, the cross-sectional design, nonprobability sampling, and unavailable covariate data limit causal interpretation and generalizability.
The Relationship Between Family Support and Medication Adherence Among Tuberculosis (TBC) Patients Hendar Ristiawan; Hendri Hadiyanto; Hadi Abdillah; Ernawati Hamidah
Healthy Tadulako Journal (Jurnal Kesehatan Tadulako) Vol. 12 No. 3 (2026)
Publisher : Faculty of Medicine, Universitas Tadulako

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22487/jw9ztr67

Abstract

Background: Tuberculosis remains a public health problem, and incomplete treatment can adversely affect recovery and community tuberculosis control. Family support may influence medication-taking behavior during therapy and may be related to treatment adherence. Objective: To determine the association between family support and medication adherence among patients receiving tuberculosis treatment in the working area of Cidahu Health Center, Sukabumi Regency. Methods: This quantitative correlational study used a cross-sectional design involving 61 tuberculosis patients selected through purposive sampling. Family support and medication adherence were categorized into low, moderate, and high levels. Because the 3 × 3 contingency table contained sparse and zero cells, the association was analyzed using the Fisher Freeman Halton exact test, with Cramer’s V as the effect-size measure. Results: Family support was significantly associated with medication adherence (p < 0.001; Cramer’s V = 0.47). Among patients with low family support, 79.3% had low adherence, whereas 66.7% of those with high family support demonstrated high adherence. Conclusion: Family support was strongly associated with medication adherence in this sample. However, the cross-sectional design precludes causal inference, and residual confounding from unmeasured clinical, behavioral, and socioeconomic factors should be considered when interpreting the findings.
The Relationship Between Family Self Efficacy and the Success of Home Care Gian Fitroh Hidayah; Hendri Hadiyanto; Asep Suryadin; Hadi Abdillah
Healthy Tadulako Journal (Jurnal Kesehatan Tadulako) Vol. 12 No. 3 (2026)
Publisher : Faculty of Medicine, Universitas Tadulako

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22487/weny1h21

Abstract

Background: Family self-efficacy plays an essential role in determining the quality of home care provided to postoperative patients. Low self-efficacy may lead to inadequate care performance and hinder optimal recovery. Purpose: To determine the relationship between family self-efficacy and the success of home care among postoperative patients at RSUD Sekarwangi. Method: This study used a quantitative approach with a cross-sectional design. A total of 30 family members who provided home care for postoperative patients were included as respondents. The General Self Efficacy Scale (GSES) was used to measure self-efficacy, while the Resident Assessment Instrument Home Care (RAI-HC) assessed home care success. Analysis technique: Data were analyzed using the Chi-Square test to examine the relationship between variables. Results: Most respondents demonstrated good self-efficacy (73.3%) and good home care success (73.3%). The Chi Square test showed a significant relationship between family self-efficacy and home care success (p = 0.000; p < 0.05). Conclusion: There is a significant relationship between family self-efficacy and the success of home care among postoperative patients at RSUD Sekarwangi. Enhancing family education and strengthening confidence are recommended to improve home care quality and support optimal patient recovery.
Eosinophilic Myocarditis: A Rare Histopathological Finding and Diagnostic Challenge in Sudden Cardiac Death Aries Maulana; Jasa Nita Listiana; Denny Mathius; Muh Husni Cangara; Natalia Widjaya
Healthy Tadulako Journal (Jurnal Kesehatan Tadulako) Vol. 12 No. 3 (2026)
Publisher : Faculty of Medicine, Universitas Tadulako

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22487/7hc5e947

Abstract

Background: Eosinophilic myocarditis (EM) is a rare inflammatory myocardial disorder that may cause arrhythmia, heart failure, cardiogenic shock, or sudden cardiac death. Objectives: To describe the forensic and histopathological findings of a fatal case of EM and emphasize appropriate interpretation of pathological diagnosis, mechanism of death, and underlying etiology. Methods: A forensic autopsy and histopathological examination were performed in a 48-year-old man who died suddenly without documented preceding cardiac symptoms. Results: Autopsy revealed cardiomegaly, myocardial discoloration and necrosis, intracavitary mural thrombi, and no significant macroscopic coronary stenosis. Histopathology demonstrated myocyte degeneration and necrosis with dense eosinophil-rich inflammatory infiltration accompanied by lymphocytes, neutrophils, histiocytes, and hemorrhagic foci. These findings strongly supported EM as the principal pathological diagnosis. However, the etiology remained undetermined because complete toxicological, hematological, parasitological, autoimmune, and immunohistochemical investigations were not documented. A fatal arrhythmia was considered a plausible mechanism of sudden death but was not directly demonstrated. Conclusions: This case highlights the importance of integrating autopsy and histopathological findings while distinguishing pathological diagnosis, probable mechanism of death, and etiological classification in sudden death associated with EM.
Maternal Malperfusion and Placental Necrosis in Sudden Maternal Death: A Forensic and Histopathological Case Analysis of Severe Preeclampsia Jasa Nita Listiana; Annisa Anwar Muthaher; Afriani Early; Muh Husni Cangara; Ressy Dwiyanti; Andini Febrianty; Zulfikar Gaffar Assegaf; Aries Maulana
Healthy Tadulako Journal (Jurnal Kesehatan Tadulako) Vol. 12 No. 3 (2026)
Publisher : Faculty of Medicine, Universitas Tadulako

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22487/5j9b3a33

Abstract

Background: Sudden maternal death associated with hypertensive disorders of pregnancy can be difficult to interpret when clinical and autopsy documentation is incomplete. Objectives: To describe a sudden maternal death in a woman with clinical and placental findings suggestive of severe preeclampsia and to emphasize the diagnostic value and limitations of placental histopathology. Methods: A forensic case of a 29-year-old gravida 3 para 2 woman at 32 weeks of gestation who was found dead at home was reviewed using available clinical records, laboratory findings, toxicology, placental gross examination, and histopathology. Results: Two weeks before death, headache, blurred vision, epigastric pain, hypertension, and proteinuria were documented. Laboratory findings included proteinuria +3, hematuria +1, and serum creatinine 2.1 mg/dL. Toxicological screening was negative. The placenta showed pale, firm infarcted areas. Histopathology demonstrated focal villous necrosis, ghost villi, and fibrinoid necrosis of maternal spiral arteries, consistent with maternal vascular malperfusion. Complete maternal organ findings and full exclusion of other major causes of sudden maternal death were unavailable. Conclusions: The findings strongly support severe preeclampsia as the underlying maternal condition associated with death; however, the immediate mechanism of death remains undetermined. Placental histopathology is valuable when integrated with complete clinical and forensic evaluation.
Determinants of Adherence to Iron Supplementation in the Anemia Prevention Program Among Pregnant Woman at Lere Health Center, Palu City Tantri Pratiwi; Muhammad Ryman Napirah; Miranti Miranti
Healthy Tadulako Journal (Jurnal Kesehatan Tadulako) Vol. 12 No. 3 (2026)
Publisher : Faculty of Medicine, Universitas Tadulako

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22487/xrsgpc39

Abstract

Background: Anemia in pregnancy remains a public health problem with serious consequences for both mothers and fetuses. Low adherence to iron supplementation persists at the Lere Community Health Center, which reports the highest anemia prevalence in Palu City. Objective: This study aimed to analyze the determinants of iron supplementation adherence among pregnant women, including knowledge, family support, frequency of antenatal care (ANC) visits, health worker education, and prenatal attachment. Methods: A cross sectional study was conducted using a purposive sampling technique among second and third trimester pregnant women. Data were collected through structured questionnaires and analyzed using logistic regression.Results: The frequency of ANC visits (p = 0.013; Exp(B) = 4.938) and health worker education (p = 0.030; Exp(B) = 6.786) significantly influenced iron supplementation adherence. Knowledge, family support, and prenatal attachment showed no significant association. The regression model demonstrated an accuracy of 86.7%.Conclusion: Optimizing ANC attendance and improving the quality of education provided by health workers are essential to enhance adherence to iron supplementation. Strengthening educational strategies and continuous monitoring should be prioritized in anemia management programs for pregnant women.

Page 45 of 45 | Total Record : 447

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