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Makara Journal of Health Research
Published by Universitas Indonesia
ISSN : 23563664     EISSN : 23563656     DOI : https://doi.org/10.7454/msk
Core Subject :
Makara Journal of Health Research (MJHR) is a peer-reviewed and scientific journal published by Universitas Indonesia. Starting from 2019 onwards, MJHR is redirecting its scope, focusing on publishing research articles relevant to non-communicable diseases (NCDs) addressing issues of surveillance, disease management and health policy in the Asia Pacific and Mediterranean countries. Relevant academic articles regarding NCDs analyzed from an integrated perspective including individual and population level, experimental and clinical approaches, epidemiology, public health, disease prevention and health promotion, diagnosis, treatment, prognosis and palliative care are welcome.
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Articles 9 Documents
 1 
Search results for , issue "Vol. 22, No. 2" : 9 Documents clear
Stressors and Their Association with Symptoms of Depression, Anxiety and Stress in Dental Students Radeef, Ali S; Faisal, Ghasak G
Makara Journal of Health Research Vol. 22, No. 2
Publisher : UI Scholars Hub

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Abstract

Background: Dental students are exposed to varying levels of stress that may affect their mental and physical health, academic performance and quality of life. This study aim was to determine the prevalence and severity of depression, anxiety and stress (DAS), and the relationships between DAS symptoms and stressors. Methods: This cross-sectional study included 257 dental students at the International Islamic University Malaysia. The prevalence and severity of DAS symptoms was measured by the Depression, Anxiety, Stress Scale (DASS-21). The stressors were self-reported by students from a list, and the relationships with the DAS symptoms were assessed. Results: The overall prevalence of DAS symptoms for depression, anxiety, and stress were 47.5%, 67.3% and 42.8%, respectively. Clinically significant depression was experienced by 9.3% of the students, anxiety by 28.8% and stress by 10.1%. Anxiety was significantly more frequent in women than in men, and anxiety scores were significantly increased in young students. The top five stressors were time management problems, fear of failing, examination and low grades; feeling of incompetence and study pressure. Conclusions: DAS symptoms occurred in dental students. Academic and personal factors produced stress that precipitated psychological distress.
Quality of Life in Pre- and Post-Treatment among Head and Neck Cancer Survivors at A Tertiary Centre, Malaysia Ludin, Salizar M; Abdullah, Che-Azunie C; Abdullah, Kahairi
Makara Journal of Health Research Vol. 22, No. 2
Publisher : UI Scholars Hub

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Background: Treatment for head and neck cancer (HNC) may result in a variety of long term consequences that impair their health and quality of life (QoL). HNC patients often are prone to have a poor health related QoL due to significant changes in vital functions. Despite researches being done in the area cancer survivors' QoL internationally, those done locally were relatively scares and not clear. The study aim to determine and compares the pre and post treatments QoL in HNC patients. Methods: A cohort study was carried out to recruit 81 newly diagnosed HNC patients purposively; pre and six months post treatment using QoL Cancer Survivor and Questionnaire-Head &Neck 35 questionnaires. .Data was analyzed for descriptive and inferential analysis. Results: A total of 40 (50%) patients participated and the result shows that QoL of HNC patients were at medium level (6.22 ± 1.8) pre-treatment, and however reduced (4.84 ± 1.16) at 6 months post treatment), despite the symptoms or problems that occur reduced post treatment compared (1.58 ± 1.25). The Pearson coefficient correlation test result shows that QoL of HNC patients pre and post treatment were strong but negatively correlated (r = -0.447, p = 0.002). Conclusion: Understanding of QoL and affecting factors in HNC patients' QoL is very crucial as it may potentially assist in designing interventions that lessen the adverse impact of this disease process and more accurately support those in active treatment, survivors, and caregivers.
Children's HIV Status and the Acceptance Stage of Grief amongst HIV-Positive Women Ristriyani, Rizka; Rachmawati, Imami N; Afiyanti, Yati
Makara Journal of Health Research Vol. 22, No. 2
Publisher : UI Scholars Hub

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Background: Women living with HIV (WLWH) commonly grieve but may pass through the grieving process until reaching the acceptance stage. We try to identify the relationship between children's HIV status and the acceptance stage of grief amongst WLWH. Method: This cross-sectional study utilised consecutive sampling of 235 HIV-positive women in Jakarta, Indonesia. The women were assessed with the Acceptance of Disease and Impairments Questionnaire (ADIQ). Results: Most of the respondents were housewives (65.5%), had been diagnosed over one year previously (74.5%), had an HIV-positive spouse (60.4%), had more than one child (51.5%) but none who were infected (73.6%) and assumed that their HIV status was caused by their spouse (50.2%). The respondents' median score of acceptance of their HIV status was relatively high (3 on a 1-4 scale). This showed a significant negative correlation between children's HIV status and the acceptance stage amongst HIV-positive women (p = 0.01). Conclusion: Mother-to-child HIV transmission may disrupt the mother's acceptance stage because of feelings of guilt and difficulty disclosing their status. Because the children's HIV status was correlated with the mother's acceptance stage, WLWH must comply with the Preventing Mother-to-Child Transmission of HIV (PMTCT) program during the perinatal period.
A Rare Case of Hutchınson-Gılford Progerıa Syndrome wıth Early Dental Loss wıthout Decay Pekdemir, Tuğçe N; Öztürk, Duygu; Çetindağ, Merve T; Akleyn, Ebru; Sarıyıldız, Cansu O; Callea, Michele; Yavuz, İzzet
Makara Journal of Health Research Vol. 22, No. 2
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Hutchinson-Gilford progeria syndrome (HGPS) is a rare autosomal recessive genetic disorder that occurs as a point mutation in the LMNA gene. It is a rare hereditary disorder, with approximately 100 cases reported in the medical literature. These patients and our case show features of aged appearance (pseudosenilism), loss of subcutaneous fat texture, growth retardation, sclerodermatous skin, ‘horse riding posture', bird-face appearance, beaked nose, high pitched voice, protruding knees and elbows, underweight, short stature, malformation of the teeth, micrognathia, hypodontia, malocclusion, craniofacial disproportion, atherosclerosis and cardiovascular disorders. Unlike typical findings of HGPS, diffuse alopecia and prominent scalp veins were not observed in our case. Patients with HGPS have an average life span of 13 years, owing to myocardial infarction and congestive heart failure and our case also has atherosclerosis and heart failure. Here, we report extra- and intraoral findings in a 24-year-old male patient with HGPS who came to our faculty with complaints about absence of teeth and psychological problems caused by absence of teeth and HGPS findings such as pseudosenilism, growth retardation and short stature. We have described necessary dental examinations and treatments for our patient and have reviewed the literature.
Correlation between Folic Acid and Homocysteine Plasma in Severe Pre-Eclampsia and Normal Pregnancy Malahayati, Inke; Serudji, Joserizal; Sulastri, Delmi
Makara Journal of Health Research Vol. 22, No. 2
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Background: Lack of folic acid intake or genetic abnormalities in folic acid metabolism was correlates with elevated plasma or serum homocysteine concentrations. This case-control analytical study aims to determine the correlation between folic acid and homocysteine levels in severe pre-eclampsia and normal pregnancy. Methods: We enrolled 46 pregnant women (age 20─35 years) with severe pre-eclampsia or normal pregnancy at a government hospital in Padang, Indonesia, between March and May 2015. The samples size was selected by consecutive sampling. Then, we determined folic acid and homocysteine levels using ELISA and statistical analysis using the independent t-test and Pearson correlation. Results: We observed a difference in folic acid levels between severe pre-eclampsia (39.48 ± 9.40 ng/mL) and normal pregnancy (47.04 ± 13.20 ng/mL, p < 0.05). A difference was also observed in homocysteine levels between pre-eclampsia (18.52 ± 0.41 pmol/mL) and normal pregnancy (17.80 ± 0.73 pmol/mL, p < 0.05). The correlation between folic acid and homocysteine in severe pre-eclampsia and normal pregnancy was negative (r = -0.034, p > 0.05 and r = -0.222, p > 0.05, respectively). Conclusions: Low folic acid levels tend to increase homocysteine levels in severe pre-eclampsia, whereas high folic acid levels tend to lower homocysteine levels in normal pregnancy.
Improved Skin Wound Healing Activity of Insulin Cream as Evidenced from the Morphological Evaluation in Guinea Pigs Mohamed, Nur-Aliana H; Mokhtar, Rafidah H; Al-Ani, Imad M; Ayob, Azizi; Misran, Misni
Makara Journal of Health Research Vol. 22, No. 2
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Background: There is no histological study evaluating the effects of insulin-containing cream on skin injury. The goal of this study was to examine the effects of insulin-containing creams on wound healing. Methods: Creams consisting of nine parts of oil and one part of aqueous phase (9:1) mixed with 1.5 mL human insulin were prepared. Eighteen male guinea pigs were divided into three groups; the control (9:1 C) group received cream without insulin. The experimental groups received Humulin N (9:1 N) and Humulin R (9:1 R) respectively. A 1 cm2 wound of 1-2 cm thickness was created in the skin. Each animal received 0.5 g of the respective creams which was topically applied once a day for 14 days. The progress of wound healing was monitored daily. Skin tissues were excised at the 14th days from the wound sites and processed for light microscopy. Results: Skin wound treated with the long acting insulin Humulin N had an accelerated wound healing process with restoration of vascular network, increased collagen deposition and early complete wound remodeling. Conclusion: Insulin cream with long acting mechanism facilitates in normalizing cell permeability, promoting vascularization, reducing exudation and stimulate proliferation of cells. These properties render insulin cream suitable for expediting wound healing.
Gingival Health Status of 12-Year-Old School Children in Jakarta: A Cross-Sectional Study Rosalien, Robbykha; Hutami, Dina F; Agustanti, Ary; Septalita, Annisa; Adiatman, Melissa; Maharani, Diah A
Makara Journal of Health Research Vol. 22, No. 2
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Background: Epidemiological data on gingival status in children is important because periodontal disease is one of the most prevalent diseases in Indonesia. This study aimed to assess the gingival health status and its associated factors among 12-year-old schoolchildren in Jakarta. Methods: This was a cross-sectional study of 12-year-old schoolchildren. There were 481 students who were recruited from 24 public and private junior high schools in Jakarta using multistage cluster proportional-to-size random sampling. Periodontal status was recorded using the community periodontal index based on World Health Organization standards. A self-completed questionnaire was given to the parents to collect information on children's backgrounds and oral health-related behaviours. Results: Only 3 of 478 participating children had healthy gums (no bleeding gums and no calculus). 99% of the children had bleeding gums and 84% had calculus. The prevalence of calculus was higher in girls than in boys. Periodontal status was not significantly related to tooth brushing habits or dental check-ups. Conclusions: Poor periodontal conditions were highly prevalent among 12-year-old schoolchildren in Jakarta. Oral health promotion and prevention strategies are urgently required.
WHO STEPS-wise Approach in Assessment of Tooth Decay and Children's Quality of Life in Indonesia Susilawati, Sri; Monica, Grace; Fadilah, R. Putri N; Hanum, Farichah
Makara Journal of Health Research Vol. 22, No. 2
Publisher : UI Scholars Hub

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Background: The high prevalence of tooth decay is a major oral health problem in Indonesia. We aimed to determine the relationship between tooth decay and quality of life in children living in rural and urban areas in Indonesia. Methods: A pilot survey was carried out with 2550 students in rural, peri-urban and urban sites in 14 provinces in Indonesia. Age groups included 6-7 years old and 11-12 years old, and we used the pathfinder survey technique. Data collected were based on the WHO STEPS-wise framework using a dental examination by the WHO form (Annex 7) and quality of life questionnaire (Annex 8, Q10). Results: Tooth decay prevalence in 6-7 years old was 88.01%, and 70.27% in the 11-12 years old age group. Children aged 6-7 years old was reported that tooth decay affected their appearance (p=0.013), caused them to avoid smiling and laughing (p=0.003), caused other children to make fun of their teeth (p=0.002) and caused them to miss school hours (p=0.005). Among 11-12 years old children, tooth decay reportedly affected their appearance (p=0.001), caused them to avoid smiling and laughing (p=0.041) and caused them to have chewing difficulty chewing (p=0.031). Conclusions: Tooth decay affects children's quality of life, especially with regard to psychological health.
Efficacy of Essential Oil Strips Containing Thymol, Eucalyptol, Menthol, Methyl Salicylate, and Peppermint Against Dental Caries Rahardjo, Anton; Gemiani, Dira; Soekanto, Sri A
Makara Journal of Health Research Vol. 22, No. 2
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Background: Strips containing essential oils are commonly used as an alternative treatment for dental caries prevention. However, their efficacy is unknown. This study aimed to test the efficacy of oral strips containing essential oils on caries prevention. Methods: This was a randomized, double-blind, placebo-controlled crossover study with 15 subjects divided into two groups: A and B. In the first week, group A (N = 8) was given strips containing thymol, eucalyptol, menthol, methyl salicylate, and peppermint (TEMMP) three times in 24 hours while group B (N = 7) was given placebo strips. In the second week, after a one-week washout period, each group was given the other product. Pre- and post-treatment evaluation was performed by measuring plaque acidity using a pH plaque indicator and determining the number of S.mutans colonies using a hand counter. Results: There was no significant difference between plaque pH and S.mutans count in subjects given TEMMP strips compared to placebo. Conclusions: The use of TEMMP essential oil strips does not significantly inhibit the growth of S.mutans or the production of plaque.

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