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The Indonesian Journal of Gastroenterology, Hepatology and Digestive Endoscopy

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Published by The Indonesian Society for Digestive Endoscopy

ISSN : 14114801 EISSN : 23028181 DOI : -

Core Subject : Health,

Medicine & Pharmacology

The Indonesian Journal of Gastroenterology, Hepatology and Digestive Endoscopy is an academic journal which has been published since 2000 and owned by 3 Societies: The Indonesian Society of Gastroenterology; Indonesian Association for the Study of the Liver; The Indonesian Society for Digestive Endoscopy. The aim of our journal is to advance knowledge in Gastroenterology, Hepatology, and Digestive Endoscopy fields. We welcome authors for original articles, review articles, and case reports in the fields of Gastroenterology, Hepatology, and Digestive Endoscopy.

Arjuna Subject : Kedokteran - Ilmu Pencernaan

Articles 771 Documents

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The COVID-19 with Gastrointestinal Symptoms: A Case Report Eka Surya Nugraha; Davin Takaryanto; Susantina Prodjosoewojo; Nenny Agustanti
The Indonesian Journal of Gastroenterology, Hepatology, and Digestive Endoscopy Vol 21, No 2 (2020): VOLUME 21, NUMBER 2, August 2020
Publisher : The Indonesian Society for Digestive Endoscopy

The COVID-19 mostly manifested as fever and pulmonary symptoms, but recent evidence demonstrated the frequent gastrointestinal symptoms in particular moderate to severe disease. Here, we present a case of a 51-years old man with confirmed COVID-19 diagnosis who was admitted with profuse acute diarrhea and nausea. He previously had a mild fever, cough, and shortness of breath. Administration of oseltamivir, levofloxacin, and chloroquine sulfate exaggerated vomiting, nausea, and increased serum level transaminase. After withdrawal, the gastrointestinal symptoms were relieved gradually. Adequate supportive treatment and fluid therapy ceased diarrhea and led to the negative result of the nasal swab RT-PCR COVID-19 after seven days.

Epstein-Barr Virus Infection as One of the Predisposition Factor for Colorectal Cancer Marcellus Simadibrata
The Indonesian Journal of Gastroenterology, Hepatology, and Digestive Endoscopy VOLUME 13, NUMBER 1, April 2012
Publisher : The Indonesian Society for Digestive Endoscopy

Correlation of Aerobic Exercise and High Nitrate Diet with Population of Eschericia Coli in the Digestive Tract of Liver Cirrhosis Individuals Retti Nurlaili; Syifa Mustika
The Indonesian Journal of Gastroenterology, Hepatology, and Digestive Endoscopy Vol 18, No 3 (2017): VOLUME 18, NUMBER 3, DECEMBER 2017
Publisher : The Indonesian Society for Digestive Endoscopy

Background: In liver cirrhosis, the population of E coli is increased. conditions such as reduced intestinal). Escherichia coli with 2 enzyme nitrate reductase (NRF and Nir) reduce nitrate to nitrite and subsequently converted to ammonia (99%) and nitric oxide (1%) in anaerobic condition. Regular aerobic exercise 2-3 times/week for 30 minutes resulted in increased 2,3-DPG which reduces the activity of E. coli to reduce nitrate to nitrite and ammonia, which only works on the anaerobic state. High Nitrate Diets lead to increased nitrate reducing bacteria such as E. coli resulting in the reduction of nitrate excess produce nitrite and ammonia in large quantities. Probiotic Lactobacillus spp. can suppress the growth of bacterial endotoxins and pathogens such as E. coli and other Enterobacteriaceae. This study aimed to determine the correlation of aerobic exercise and a high nitrate diet in gastrointestinal populations of Escherichia coli gastrointestinal tract in patient with liver cirrhosis.Method: This was a descriptive-experimental study in liver cirrhosis patients Child Pugh A/B in outpatient clinic Saiful Anwar Hospital in August 2015. Respondents were asked to fill out a questionnaire with information about the demographic data, the nitrate diet, aerobic exercise, other medical data and sanitation, and stool samples were taken for faecal culture. Eta Correlation statistical test was used to determine the correlation of aerobic exercise and a high nitrate diet high in population of E. coli. The significant difference are indicated by p 0.005.Results: A total of 36 patients diagnosed with liver cirrhosis Child Pugh A/B, 14 (39%) underwent aerobic exercise 3x /week, as many as 25 (70%) consume a high nitrate diet. There was a strong relationship between aerobic exercise and high nitrate diet with population of E. coli (Ƞ = 0.725; p 0.05).Conclusion: There was a strong relationship between aerobic exercise and high nitrate diet with a population of E. coli in liver cirrhosis. Giving probiotics in patients with liver cirrhosis suppressed the population of E. coli.

Relationship between serum zinc concentration and neutrophil phagocytic function in liver cirrhosis patients Siti Nurdjanah; Sigit Widyatmoko; R M Arjono
The Indonesian Journal of Gastroenterology, Hepatology, and Digestive Endoscopy VOLUME 7, ISSUE 1, April 2006
Publisher : The Indonesian Society for Digestive Endoscopy

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24871/7120061-5

Background: Liver cirrhosis patients are susceptible to infection. The incidence of infections depends on several factors. One of the factors is decreasing immune system i.e. the deterioration of neutrophil phagocytic function. The deterioration of neutrophil phagocytic function is caused by complement deficiency, bowel endotoxemia, decreasing tuftsin activity, and zinc deficiency. Zinc deficiency is caused by impairment of bowel absorption and increasing zinc excretion by urine. Zinc influences the specific and non specific immune system. Aim: To determine whether there is relationship between serum zinc concentration with neutrophil phagocytic function in liver cirrhosis patients. Subject Method: This was a cross-sectional study from August 2004 until September 2005. Study population are ambulatory liver cirrhosis patients and in patient liver cirrhosis. Correlation analysis was done to asses relationship between zinc concentration and neutrophil phagocytic function, which used Nitro Blue Tetrazolium (NBT) dye reduction test. Result: There were 58 subjects fulfilled the criteria. The mean of serum zinc concentration was 114 mmol/L. The mean of NBT was 3.4 ± 3.1%. The coefficient correlation between zinc serum concentration and neutrophil phagocytic function was 0.13, p= 0.58. Conclusion: There was a weak and non significant positive correlation between serum zinc concentration with neutrophil phagocytic function in liver cirrhosis patients. Keywords: zinc, neutrophil phagocytic function, liver cirrhosis

The clinical features of COVID-19 patients with positive viral RNA stool test results and possibility of fecal-oral transmission : A Systematic Review Selina Natalia; Felicia Imanuella Thorion; Luky Adlino; Clifford Eltin John; Andree Kurniawan; Nata Pratama Hardjo Lugito
The Indonesian Journal of Gastroenterology, Hepatology, and Digestive Endoscopy Vol 22, No 1 (2021): VOLUME 22, NUMBER 1, April 2021
Publisher : The Indonesian Society for Digestive Endoscopy

Objective : Coronavirus disease 2019 (COVID-19) has been declared as an international public health emergency by the World Health Organization (WHO), with outbreaks in over 200 countries and causing over 390,000 deaths globally. ACE-2 receptors are highly expressed in the upper and lower gastrointestinal system, providing a prerequisite for SARS-CoV-2 infection in the gastrointestinal tract. In addition, over half of the COVID-19 patients have viral nucleic acid detected in their feces and almost one-quarter of the cases, the stool samples test positive even when respiratory samples are negative. The aim of this systematic review is to summarize literature and to evaluate the clinical characteristics of patients with positive viral RNA stool test for COVID-19 and if there is a possibility of fecal-oral transmission of SARS-CoV-2 virus.Method : This systematic review has been registered in PROSPERO (CRD42020183049). A systematic search of the literature for observational study and randomized control trial was conducted in PubMed central and Google Scholar through May 5th, 2020. Three reviewers independently searched and selected. The risk of bias was evaluated using Newcastle-Ottawa Quality assessment tool.Results : 340 articles were screened, then from which eight articles were selected. Of eight articles that were included in this study, we sought for three main categories of the clinical manifestation; gastrointestinal, respiratory, and others. Each study was reviewed systematically to gain demographic data and evidence regarding the possibility of fecal oral transmission in SARS-CoV-2. Two studies reported prolongation of positive stool test results after the respiratory specimen conversion to negative which support the theory of fecal oral transmission.Conclusion : In conclusion, diarrhea, cough, and fever are the most common clinical manifestations in COVID-19 patients with positive RNA stool test results. Fecal oral transmission may be possible due to the ACE-2 receptors in the lining of the gastrointestinal tract. RNA stool test should be used as addition in discharging COVID-19 patients.

Correlation between Aspartate Aminotransferase to Platelet Ratio Index Score and the Degree of Esophageal Varices with Liver Cirrhosis Imam Supriyanto; Suyata Suyata; Syadra Bardiman Rasyad; Fuad Bakry
The Indonesian Journal of Gastroenterology, Hepatology, and Digestive Endoscopy VOLUME 13, NUMBER 3, Desember 2012
Publisher : The Indonesian Society for Digestive Endoscopy

ABSTRACTBackground: Esophageal varices is the most common complication in liver cirrhosis. Bleeding varices is a serious complication causing increased mortality rate. In anticipation of those complications, the role of screening test is essential. Endoscopy is the standard method for assessing esophageal varices, but it carries certain risks for patients if it is contraindicated. Moreover, it is an invasive, expensive and uncomfortable procedure. Accordingly, a non-invasive method, aspartat aminotransferase to platelet ratio index (APRI) score, has been developed for evaluating esophageal varices. Method: An analytic cross-sectional observational study was conducted in patients with liver cirrhosis who underwent endoscopy between March 2011 and August 2012. Data were obtained from medical records of hospitalized patients in Mohammad Hoesin General Hospital. The degree of esophageal varices was assessed based on endoscopic findings and APRI score. Spearman test was performed to analyze the correlation between APRI score and the degree of esophageal varices.Results: There were 55 patients, 30 (54.5%) male and 25 (45.5%) female patients, with a range of age between 15-70 years and a mean value of age of 47.09 ± 12.8. APRI score 0.5 was found in 21.81% subjects, APRI score of 0.5-1.5 was obtained in 41.81% subjects and APRI score 1.5 was noted in 36.36% subjects with a mean value of 2.32 ± 3.92. There was a correlation between APRI score and degree of esophageal varices with p = 0.011 Conclusion: APRI score can indirectly predict esophageal varices in patients with liver cirrhosis. Keywords: APRI score, the degree of esophageal varices, liver cirrhosis

Inducing and Aggravating Factors of Gastroesophageal Reflux Symptoms Radhiyatam Mardhiyah; Ari Fahrial Syam; Siti Setiati
The Indonesian Journal of Gastroenterology, Hepatology, and Digestive Endoscopy Vol 17, No 3 (2016): VOLUME 17, NUMBER 3, December 2016
Publisher : The Indonesian Society for Digestive Endoscopy

Gastroesophageal reflux disease (subsequently abbreviated as GERD) is a disease commonly found in the community. Several factors have been recognized as inducing and aggravating factors of GERD symptoms such as older age, female gender, obesity, smoking habit, alcohol consumption, certain diet and poor eating habit like eating fatty, spicy, and acid food.

The Efficacy of Low Dose Captopril Adjuvant for Natriuresis in Patient with Liver Cirrhosis with Ascites Who Have Received Furosemide and Spironolacton Suyatmi Suyatmi; Bantar Suntoko; F. Sumanto; Hirlan Hirlan
The Indonesian Journal of Gastroenterology, Hepatology, and Digestive Endoscopy VOLUME 2, NUMBER 3, December 2001
Publisher : The Indonesian Society for Digestive Endoscopy

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24871/2320011-5

Background: The ideal therapy for ascites in liver cirrhosis is a low sodium diet and a combination of furosemide and spironolacton. However, this still sometimes does not produce satisfactory Results, even after increasing the dose of the diuretic. Such failure occurs due to the influence of the Renin Angiotensin Aldosterone (RAA) system. Low doses of ACE inhibitors (captopril) should improve renal blood flow and increase filtration at the glomeruli, thus increasing natriuresis without causing haemodynamic imbalance. Study aim: To discover the natriuretic and diuretic effects of low dose captopril adjuvant in patients with liver cirrhosis who have received furosemide and spironolacton by measuring urinary sodium and 24-hour urine output. Materials and method: This study was conducted on in- and out- patients with liver cirrhosis and Ascites at the Dr. Kariadi Central Public Hospital, Semarang, who met the inclusion and exclusion criteria. The study took place from June 1st, 1997 to March 31st, 1998, and included 40 cases of liver cirrhosis with ascites. Study design: Open comparative randomized clinical trial with permuted blocks. All of the patients received a low fat diet, 40 mg of furosemide, 3x50 mg of spironolacton for 2 weeks, and patients with a urinary sodium level was below 80 mEq/L were randomized into two groups: group A receiving 3 x 6.25 mg of captopril, and group B receiving standard therapy. Results: Variable Pre- treatment Post – treatment p Group A : Urinary sodium level (meq/L) 65.450 ± 16.577 109.950 ± 49.109 0.001 24-hour urine output (cc) 1138.750 ± 480.438 1381.250 ± 394.441 0.004 Group B: Urinary sodium level (meq/L) 68.30 ± 12.85 91.750 ± 64.04 0.103 24-hour urine output (cc) 1390 ± 448.27 1392.50 ± 713.46 0.988 The pre- and post- treatment Results for Group A were significantly different. The pre- and post- treatment Results for Group B were not significantly different. Conclusion: Low dose (3 x 6.25 mg) captopril adjuvant in patients with liver cirrhosis and ascites who have received standard doses of furosemide and spironolacton could increase natriuresis and diuresis without causing haemodynamic imbalance. Key words: Captopril, liver cirrhosis, ascites

Red Cell Distribution Width to Platelet Ratio: in a Search of Non-Invasive Liver Fibrosis Biomarker Andri Sanityoso Sulaiman
The Indonesian Journal of Gastroenterology, Hepatology, and Digestive Endoscopy Vol 19, No 3 (2018): VOLUME 19, NUMBER 3, December 2018
Publisher : The Indonesian Society for Digestive Endoscopy

Gastric Inflammatory Fibroid Polyp in Children Badriul Hegar; Tatang Puspanjono
The Indonesian Journal of Gastroenterology, Hepatology, and Digestive Endoscopy VOLUME 8 ISSUE 2 August 2007
Publisher : The Indonesian Society for Digestive Endoscopy

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24871/82200763-66

Inflammatory fibroid polyp (IFP) constitutes as a chronic inflammatory lesion that is generally located in the gastric (gastric inflammatory fibroid polyp). The lesion originates from the submucosal tissue of the gastrointestinal tract and progress into a polypoid mass. Inflammatory fibroid polyp is rarely found in children and the cause is not definitely known. A case of a four-year old boy with recurrent paleness for 3 months has been reported. At the beginning, the patient was suspected of haemolytic anaemia. Except the hemoglobin level ( 5 g/dL), other laboratorium examination did not support the working diagnosis. During the last one months period, the patient also complained of recurrent abdominal pain and vomiting. On the abdominal ultrasonography (USG) and endoscopy, a mass that covered most of the gastric lumen was detected. Based on that finding, gastrectomy and mass removal were conducted. The pathologic anatomy examination proved the presence of an inflammatory fibrous polypoid. Follow-up untill 12 months showed no any complaint and abnormalities on endoscopic examination. Since there was no consensus regarding the follow-up period following the procedure, the evaluation of this patient would be conducted every 2-3 years. Keywords: inflammatory fibroid polyp, tumor, gastric, children

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Murdani Abdullah

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ina.jghe@gmail.com

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ina.jghe@gmail.com

Editorial Address
Divisi Gastroenterologi, Departemen Ilmu Penyakit Dalam, FKUI/RSUPN Dr. Cipto Mangunkusumo, Jl. Diponegoro No. 71 Jakarta 10430 Indonesia

Location
Kota adm. jakarta pusat,

Dki jakarta

INDONESIA

Abstract

Abstract

Abstract

Abstract

Abstract

Abstract

Abstract

Abstract

Abstract

Abstract

Home Page

OAI Link

Editorial Team

Contact

Reviewer

Google Scholar

Contact Name Murdani Abdullah

Contact Email ina.jghe@gmail.com

Phone +6285891498517

Journal Mail Official ina.jghe@gmail.com

Editorial Address Divisi Gastroenterologi, Departemen Ilmu Penyakit Dalam, FKUI/RSUPN Dr. Cipto Mangunkusumo, Jl. Diponegoro No. 71 Jakarta 10430 Indonesia

Location Kota adm. jakarta pusat, Dki jakarta INDONESIA

Abstract

Abstract

Abstract

Abstract

Abstract

Abstract

Abstract

Abstract

Abstract

Abstract

Contact Name
Murdani Abdullah

Contact Email
ina.jghe@gmail.com

Phone
+6285891498517

Journal Mail Official
ina.jghe@gmail.com

Editorial Address
Divisi Gastroenterologi, Departemen Ilmu Penyakit Dalam, FKUI/RSUPN Dr. Cipto Mangunkusumo, Jl. Diponegoro No. 71 Jakarta 10430 Indonesia

Location
Kota adm. jakarta pusat,

Dki jakarta

INDONESIA