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PUSAT RISET DAN INOVASI NASIONAL UNIVERSITAS SAINS DAN TEKNOLOGI KOMPUTER Alamat: Jl. Majapahit No.304, Palebon, Kec. Pedurungan, Kota Semarang, Jawa Tengah 50199
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Jurnal Riset Rumpun Ilmu Kesehatan (JURRIKES)
Published by Pusat Riset dan Inovasi Nasional
ISSN : 28289366     EISSN : 28289374     DOI : 10.55606
Core Subject : Health,
Health Professions Medicine & Pharmacology Nursing Public Health
Sub Rumpun ILMU KESEHATAN UMUM 1 Kesehatan Masyarakat 2 Keselamatan dan Kesehatan Kerja (Kesehatan Kerja; Hiperkes) 3 Kebijakan Kesehatan (dan Analis Kesehatan) 4 Ilmu Gizi 5 Epidemiologi 6 Teknik Penyehatan Lingkungan 7 Promosi Kesehatan 8 Ilmu Asuransi Jiwa dan Kesehatan 9 Kesehatan Lingkungan 10 Ilmu Olah Raga 11 Bidang Kesehatan Umum Lain Yang Belum Tercantum Sub Rumpun ILMU KEPERAWATAN DAN KEBIDANAN 1 Ilmu Keperawatan 2 Kebidanan 3 Administrasi Rumah Sakit 5 Entomologi (Kesehatan, Fitopatologi) 6 Ilmu Biomedik 7 Ergonomi Fisiologi Kerja 8 Fisioterapi 9 Analis Medis 10 Fisiologi (Keolahragaan) 11 Reproduksi (Biologi dan Kesehatan) 12 Akupunktur 13 Rehabilitasi Medik 14 Bidang Keperawatan & Kebidanan Lain Yang Belum Tercantum Sub Rumpun ILMU PSIKOLOGI 1 Psikologi Umum 2 Psikologi Anak 3 Psikologi Masyarakat 4 Psikologi Kerja (Industri) 5 Bidang Psikologi Lain Yang Belum Tercantum Sub Rumpun ILMU FARMASI 1 Farmasi Umum dan Apoteker 2 Farmakologi dan Farmasi Klinik 3 Biologi Farmasi 4 Analisis Farmasi dan Kimia Medisinal 5 Farmasetika dan Teknologi Farmasi 6 Farmasi Makanan dan Analisis Keamanan Pangan 7 Farmasi Lain Yang Belum Tercantum
Arjuna Subject : Keperawatan - Keperawatan (Lain-Lain)
Articles 295 Documents
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Wajahku Cerah dan Glowing: Efektivitas Afirmasi Positif untuk Mengurangi Tingkat Stres Rida Yanna Primanita; Puput Nofia Rahma
JURNAL RISET RUMPUN ILMU KESEHATAN Vol. 4 No. 1 (2025): April : Jurnal Riset Rumpun Ilmu Kesehatan
Publisher : Pusat riset dan Inovasi Nasional

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55606/jurrikes.v4i1.4455

Abstract

This study aims to examine the effectiveness of positive affirmations in reducing stress levels and their impact on physical conditions, particularly among university students. The research employed a quasi-experimental method with a One Group Pretest-Posttest design. The sample consisted of 7 psychology students from Universitas Negeri Padang (class of 2024), selected using a purposive sampling technique. The intervention involved performing positive affirmations independently for 30 days. The results showed a significant reduction in stress levels after the intervention, as evidenced by pretest and posttest scores. This stress reduction also positively affected physical conditions, such as brighter and healthier facial skin. The findings align with previous research, highlighting that positive affirmations can alleviate stress by enhancing positive emotions and stimulating the production of anti-stress hormones. Positive affirmations offer a practical method for improving mental and physical well-being, particularly for students.
Hubungan Durasi Penggunaan Gadget dengan Kejadian Mata Lelah (Astenopia) pada Remaja SMAN 1 Garut Buyung Reza Muhammad; Andri Nugraha; Eti Suliyawati; Risma Yulyyawati
JURNAL RISET RUMPUN ILMU KESEHATAN Vol. 4 No. 1 (2025): April : Jurnal Riset Rumpun Ilmu Kesehatan
Publisher : Pusat riset dan Inovasi Nasional

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55606/jurrikes.v4i1.4463

Abstract

Continuous use of gadgets over a long period of time can emit short waves of high energy which can penetrate the eyes and ultimately cause photochemical damage to retinal cells. Excessive use of gadgets will have a negative impact on teenagers, one of which is a decline in eye health. Asthenopia is a disease experienced by the eye because the eye muscles are forced to work hard, especially when they have to look at close objects for a long time. The aim of this research is to determine the relationship between the duration of gadget use and the incidence of eye fatigue (asthenopia) in teenagers at SMAN 1 Garut. The research method used was a quantitative approach with a cross sectional research design. The population in this study was 1374 students and a sample of 94 respondents was obtained using puposive sampling techniques. Data was collected using a gadget usage duration questionnaire and a Visual Fatigue Index (VFI) questionnaire, then the data was analyzed using the Chi Square test. The results of this study show that there is a significant relationship between the duration of gadget use and the incidence of eye fatigue (asthenopia) with a p-value = 0.000 where p <0.05. So it can be concluded that there is a relationship between the duration of gadget use and the incidence of eye fatigue (asthenopia) in teenagers at SMAN 1 Garut. This research is useful as insight that there are negative impacts from excessive use of gadgets, so it is recommended that teenagers apply time limits on gadget use to prevent an increase in the incidence of asthenopia.
Literature Review: Analisis Khasiat Tanaman Pala (Myristica Fragnans Houtt) dalam Pengobatan Halitosis Oleh Bakteri Saeful Amin; Naila Naziba; Hayuning Putri Ambi; Salsabila Sasikirana
JURNAL RISET RUMPUN ILMU KESEHATAN Vol. 4 No. 1 (2025): April : Jurnal Riset Rumpun Ilmu Kesehatan
Publisher : Pusat riset dan Inovasi Nasional

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55606/jurrikes.v4i1.4475

Abstract

Halitosis, or bad breath, is a multifactorial condition that is often caused by anaerobic bacterial activity in the oral cavity, especially on the dorsum surface of the tongue. The use of natural ingredients as an alternative halitosis treatment is a concern, one of which is the nutmeg plant (Myristica fragrans), which has various active compounds such as essential oils, saponins, flavonoids, and alkaloids. This study aims to assess the potential of nutmeg plants in inhibiting the growth of bacteria that cause halitosis through a literature review of 30 national and international journals within the last five years. The results showed that nutmeg extracts, both from seeds, pulp, and leaves, have antibacterial activity against various types of halitosis-causing bacteria such as Streptococcus mutans, Staphylococcus aureus, and Escherichia coli. This activity is obtained through the mechanism of cell membrane damage and inhibition of bacterial cell wall synthesis by bioactive compounds in nutmeg plants. Therefore, nutmeg has potential as a natural antibacterial agent in the management of halitosis.
Pengaruh Media Poster terhadap Pengetahuan dan Sikap tentang Kesehatan Mental pada Remaja di SMAN 5 Kota Jambi Magda Carrina Aurora; Ismi Nurwaqiah Ibnu; Vinna Rahayu Ningsih
JURNAL RISET RUMPUN ILMU KESEHATAN Vol. 4 No. 1 (2025): April : Jurnal Riset Rumpun Ilmu Kesehatan
Publisher : Pusat riset dan Inovasi Nasional

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55606/jurrikes.v4i1.4480

Abstract

Mental health is a condition in which a person is free from all symptoms of mental disorders. Anxiety disorder is the most common mental disorder experienced by adolescents and depression reaches 26.7%. The purpose of this study was to determine the knowledge and attitudes of adolescents through poster media both before and after interventions related to mental health. The type of research used is quantitative with one group pre-test post-test method, with intervention using poster media and questionnaires as data collection tools at SMAN 5 Jambi City. The sample in this study amounted to 30 respondents and was tested using the Paired T-Test statistical test. The pre-test results showed that the percentage of knowledge before the intervention was 66.7% to 100% after the intervention and the percentage of attitude before the intervention was 76.7% to 96.7%. After the intervention on mental health, there was an increase in knowledge with P-Value = <.001 and an increase in attitude with P-Value = <.001. This study shows that there is an influence on knowledge and attitudes before and after the intervention of poster media on mental health at SMAN 5 Jambi City. It is recommended to hold interactive discussions with counseling teachers in schools aimed at increasing adolescents' understanding of mental health and being able to reduce the stigma of the surrounding environment so that students do not feel afraid or embarrassed to seek help.
The Effectiveness of Oxytocin Hormone Massage in Increasing Breast Milk Production Ellyzabeth Sukmawati
JURNAL RISET RUMPUN ILMU KESEHATAN Vol. 3 No. 2 (2024): Oktober : Jurnal Riset Rumpun Ilmu Kesehatan
Publisher : Pusat riset dan Inovasi Nasional

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55606/jurrikes.v3i2.4489

Abstract

The aim of this study was to assess the impact of oxytocin massage on breast milk production in postpartum mothers. This research employed a quasi-experimental approach, specifically utilizing a pretest-posttest control group design. The study population consisted of all normal postpartum mothers receiving care at a Midwifery Independent Practice located in Kesugihan District, Cilacap Regency. A total of 30 participants were selected through purposive sampling. Data were analyzed using the Wilcoxon test to determine statistical significance. Prior to the intervention, the average breast milk production was measured at 22.82 cc/ml. Following the administration of oxytocin massage using fennel oil, the average milk volume significantly increased to 87.58 cc/ml. These results indicate that oxytocin massage is an effective intervention for enhancing breast milk production in postpartum mothers.  
Aktivitas Antioksidan dan Organoleptik Minuman Probiotik Kombucha Bunga Telang (Clitoria ternatea L) Terhadap Variasi Konsentrasi Madu Raisa Fadilla
JURNAL RISET RUMPUN ILMU KESEHATAN Vol. 4 No. 1 (2025): April : Jurnal Riset Rumpun Ilmu Kesehatan
Publisher : Pusat riset dan Inovasi Nasional

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55606/jurrikes.v4i1.4499

Abstract

This study aimed to evaluate the effect of varying honey concentrations on the antioxidant activity, chemical properties, and organoleptic quality of a probiotic kombucha beverage prepared from Clitoria ternatea L. The research was motivated by increasing exposure to free radicals due to environmental pollution and the demand for alternative natural antioxidants. Kombucha was produced with honey concentrations of 10%, 20%, and 30% (w/v), and analyses were performed using the DPPH assay for antioxidant activity, measurements of pH, total acidity, and total phenolic content for chemical properties, as well as sensory evaluations by trained panelists. The results showed that kombucha with 10% honey exhibited the lowest IC₅₀ value, indicating the highest antioxidant activity, while higher concentrations increased the total phenolic content without significantly enhancing the effective antioxidant potential. These findings suggest that excessive honey addition does not necessarily improve the functional benefits of the product, indicating the need for further formulation optimization to develop a high-quality, marketable probiotic beverage.
Potensi Kaempferol dan Kalkon Tergeranilasi Sebagai Kandidat Terapi Penyakit Jantung Koroner (PJK) Melalui Pendekatan Molecular Docking Saeful Amin; Tevani Almanda Ramdani; Maitsa Gita Salsabila; Teguh Nizar Zulmi
JURNAL RISET RUMPUN ILMU KESEHATAN Vol. 4 No. 1 (2025): April : Jurnal Riset Rumpun Ilmu Kesehatan
Publisher : Pusat riset dan Inovasi Nasional

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55606/jurrikes.v4i1.4504

Abstract

Coronary heart disease (CHD) is one of the leading causes of death worldwide due to impaired blood and oxygen supply to the heart muscle. This study aims to explore the potential of two natural compounds—kaempferol from Moringa oleifera and geranylated chalcone (GTDC) from Artocarpus altilis—as therapeutic candidates for CHD through a molecular docking approach. Medicinal chemistry analysis revealed that kaempferol exhibits significant affinity for the NF-κB protein, forming key hydrogen bonds with residues involved in the inflammatory process of atherosclerosis. Meanwhile, GTDC demonstrates strong binding to the P2Y12 receptor, which plays a crucial role in platelet aggregation, with a docking score lower than that of the natural ligand ADP. Structurally, hydroxyl group positioning and the lipophilic geranyl chain enhance both bioactivity and pharmacokinetic properties. In conclusion, a medicinal chemistry approach involving in silico docking, structure–activity relationship (SAR) analysis, and ligand optimization strategies confirms the potential of kaempferol and GTDC as promising multifunctional therapeutic agents for CHD. Further validation through in vivo studies and clinical testing is required.
Peran Kimia Medisinal dalam Pengembangan Obat Anti Sars Cov-2: Eksplorasi Senyawa Bioaktif dari Teh Hijau (Camellia Sinensis) Fitya Fithrotun Najiah; Citra Kusumaningsih; Saeful Amin; Hanifiani Kamila
JURNAL RISET RUMPUN ILMU KESEHATAN Vol. 4 No. 1 (2025): April : Jurnal Riset Rumpun Ilmu Kesehatan
Publisher : Pusat riset dan Inovasi Nasional

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55606/jurrikes.v4i1.4505

Abstract

COVID-19 is a viral respiratory disease that has caused a global health emergency and was declared a pandemic by the World Health Organization. The lack of certain drug molecules or treatment strategies for this disease is making it worse. Therefore, effective drug molecules are urgently needed to fight COVID-19. Specific therapies for the SARS-COV2 virus are still being developed in several countries around the world. One of the molecular targets that is thought to be specific to SARS-COV 2 is 3CLpro or the main protease of the COVID-19 virus which is an important enzyme to be able to replicate related viruses. The purpose of this study is to explore the role of medicinal chemistry in the development of anti-sars-cov 2 drugs through the exploration of bioactive compounds from natural sources, namely green tea. Green tea (Camellia sinensis) also contains eight native monomeric catechins or polyphenolic compounds. The method used was literature review with analysis of 3 selected articles from international databases such as PubMed, ScienceDirect, and Springer, as well as SINTA accredited national journals. The results showed that all test compounds except caffein had stronger binding energy than lopinavir. Epicatecin and catechin have the same binding energy value as lopinavir, which is -7.1 kcal/mol. Catechin gallate and epicatechin gallate have the strongest bond among all test compounds because they have the most negative AG, namely -9.0 and 8.2 kcal/mol.
Studi Literatur : Penambatan Senyawa Komponen Tanaman Kumis Kucing ( Orthosiphon Stamineus Benth ) Sebagai Diuretik Menggunakan Metode Docking Sefira Novi Ariyanto; Saeful Amin; Eva Sucianti; Fitria Mutiara Rohmah
JURNAL RISET RUMPUN ILMU KESEHATAN Vol. 4 No. 1 (2025): April : Jurnal Riset Rumpun Ilmu Kesehatan
Publisher : Pusat riset dan Inovasi Nasional

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55606/jurrikes.v4i1.4511

Abstract

Orthosiphon stamineus Benth., commonly known as kumis kucing, is a widely recognized medicinal herb in traditional medicine, particularly valued for its diuretic properties. This study aims to evaluate the potential of active compounds in O. stamineus as diuretic agents through an in silico approach using molecular docking methods. A total of 98 compounds were screened against three diuretic target receptors: 1Z9Y (furosemide receptor), 3HS4 (acetazolamide receptor), and 3VHU (spironolactone receptor). The docking results revealed that lithospermic acid I, dicaffeoyl tartaric acid, and orthosiponone C exhibited lower binding energies compared to standard ligands, indicating higher affinity and stronger molecular interaction stability. Molecular visualization showed that these compounds formed specific interactions, such as hydrogen bonds and π-π stacking, resembling the binding mechanisms of synthetic diuretics. This study highlights the significant potential of O. stamineus to be developed into a natural diuretic phytopharmaceutical. However, further validation through in vitro and in vivo studies is necessary to confirm their efficacy and safety in complex biological systems.
Hubungan Pengetahuan, Konsumsi Makanan Kariogenik dan Kebiasaan Menggosok Gigi dengan Kejadian Karies Gigi pada Remaja di One Icon Dental Clinic Gresik Devia Dwi Ramadanty; Ervi Suminar; Diah Fauzia Zuhroh
JURNAL RISET RUMPUN ILMU KESEHATAN Vol. 4 No. 1 (2025): April : Jurnal Riset Rumpun Ilmu Kesehatan
Publisher : Pusat riset dan Inovasi Nasional

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55606/jurrikes.v4i1.4539

Abstract

Dental caries is damage to hard tooth tissue caused by bacterial metabolism in plaque that results in demineralization. This study aims to analyze the relationship between knowledge, consumption of cariogenic foods and tooth brushing habits with the incidence of dental caries in adolescents at One Icon Dental Clinic Gresik. Using an analytical survey method with a cross-sectional design, this study involved 118 adolescent respondents selected through accidental sampling. Data were collected using a questionnaire and analyzed using the chi square and Spearman Rank tests. The results showed a significant relationship between knowledge (p = 0.000, r = 0.621), consumption of cariogenic foods (p = 0.000, r = 0.792), and tooth brushing habits (p = 0.043) with the incidence of dental caries. It can be concluded that there is a relationship between the three variables and the incidence of dental caries in adolescents at One Icon Dental Clinic Gresik

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