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Journal of Global Pharma Technology
Published by Universitas Udayana
ISSN : 09758542     EISSN : -     DOI : -
Core Subject : Health,
Medicine & Pharmacology
ournal of Global Pharma Technology is a monthly, open access, Peer review journal of Pharmacy published by JGPT Journal publishes peer-reviewed original research papers, case reports and systematic reviews. The journal allows free access to its contents, which is likely to attract more readers and citations to articles published in JGPT. JGPT publishes original research work that contributes significantly to the scientific knowledge in pharmacy and pharmaceutical sciences- Pharmaceutics, Novel Drug Delivery, Pharmaceutical Technology, Cosmeticology, Biopharmaceutics and Pharmacokinetics, Pharmacognosy, Natural Product Research, Medicinal Chemistry, Computational Chemistry and Molecular Drug Design, Pharmaceutical Analysis, Pharmacology, Pharmacy Practice, Clinical and Hospital Pharmacy, Cell Biology, Genomics and Proteomics, Pharmacogenomics, Bioinformatics, Biotechnology and Applied Computer Technology. For this purpose we would like to ask you to contribute your excellent papers in pharmaceutical sciences.
Arjuna Subject : Kedokteran - Onkologi
Articles 2,439 Documents
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Histological and Anatomical Study of Cluster Pregnancy in Abortion Women at Al-Zahraa Teaching Hospital Zainab Sajid Mohammed
Journal of Global Pharma Technology Volume 11 Issue 03
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Abstract

The contemporary revision was accompanied at Al-Zahraa-Teaching -Hospital for Obstetrics. This research comprised a histo-pathological study of women distress from cluster pregnancy in Najaf Governorate, who reviewed the obstetrics department at Al-Zahraa-Teaching-Hospital for the period from 1/9/2017 to 5/2/2018.About (10) of women with cluster pregnancies, (5) cases of complete cluster pregnancies and (5) cases of partial cluster pregnancy. The range age of women with cluster pregnancies ranged from (25-15) y. The consequences of the anatomical and histological revision of women with cluster pregnancy showed that there were two types of cluster pregnancies: full cluster pregnancy and partial cluster pregnancy. Also revealed that the placenta and the fetus looked as a block on the fluid-filled bags analogous to the grape cluster where the size of these bags about (8 * 8). It was also distinguished that the fetus and placenta were not distinctive in a clear and completely slanted. However the results indicated for women with partial cluster pregnancy that the fetus and a bulky partition of the placenta appeared in the form of a mass container on the bags filled with liquids, which were in the form of irregular clusters similar to the cluster of grapes, where the size of these bags about (5 * 5) .As noted that the fetus completely mutilated or non-existent but a minor portion of the placenta lingered intact and distinctive.Keywords: Molar pregnancy, Partial molar pregnancy, Abortion woman.
Effects of Environmental Problems on Human Healthy in Iraq: A Review Aqeel M. Ali Al-Lami
Journal of Global Pharma Technology Volume 12 Issue 01
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Abstract

Pollution consider the most dangerous that faced by human and living organisms on the earth,  oxygen and water is the necessary sources  for our life,  air and water pollution effects on human, animals and plants .Ecology study the relations between living things and its habitat forming certain ecosystem. Ecosystems explain any relation types between living organism and the environment. There are many problems in earth affected continue of life, ozone depletion permit  to entry of  U.V. rays from sun to earth,  and cause increase  dangerous  for human, animals, microorganisms, and plants. Desertification and deforestation in lands acts for decreasing of vegetation area. Biological diversity must be stay with no effects, also decreasing in fresh water determine life stability.Keywords: Pollution, Ozone, Health, Cancer.
Ultrasonic Synthesis and Anti-Microbial Screening of Some 1, 3, 4-Thiadiazole Derivatives Mustafa K. Shneshil
Journal of Global Pharma Technology Volume 09 Issue 12
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Abstract

Some novel1,3,4-thiadiazole derivatives (1a-10a) were greenly synthesized by the reaction of substituted benzoic acid with thiosemicarbazide in the presence of phosphorus ox chloride (POCl3) under ultrasonic irradiation forming2-substituted phenyl-5-amino-1,3,4-thiadiazole (1-10). The later were reacted with benzoyl chloride under Schotten-Baumann conditions to give the target molecule 2-substituted phenyl-5(N-benzoyl)-amino-1, 3, 4-thiadiazole (1a-10a). The structures of the compounds synthesized identified by using spectral analysis methods (F.T-IR, 1H-NMR and13C-NMR). The compounds (1a-10a) screened for anti-microbial (Staphylococcus aureus, Staphylococcus epidermidis, Micrococcus luteus, Bacillus cereus, Escherichia coli, and Pseudomonas aeruginosa) activities using disc diffusion method. The minimum inhibitory concentrations (MICs) of the compounds also calculated by agar streak dilution Method the compounds (1a and 5a) were the most active compounds against the above strains of microbes.Keywords: Green chemistry, Ultrasonic, 1, 3, 4-Thiadiazole, Amide, Anti-microbial. 
Study of Proximate and Nutritional Composition of Leaves of Grewia tiliaefolia Vahl Rajesh Kumar Vaspri
Journal of Global Pharma Technology Volume 11 Issue 02 (2019) Feb. 2019
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Abstract

ABSTRACTObjective: The present study was aimed to assess nutritional value of the leaf of Grewia tiliaefolia Vahl belonging to the family tiliaceae. The parameters included proximate analysis of the leaves of Grewia tiliaefolia Vahl for carbohydrates, proteins, moisture, ash, and crude fiber. The determination of minerals of the leaves of the plant were magnesium, calcium, copper, iron, zinc, sodium and potassium. Methods: The methods employed for determination of proximate and nutritional value of leaf of Grewia tiliaefolia was according to standard procedures (AOAC). The instrument used was spectrophotometer. Results and conclusion: The results concluded that the proximate analysis of Grewia tiliaefolia Vahl leaf showed presence of carbohydrates, proteins, moisture, ash and crude fiber. Mineral contents like calcium, magnisium iron, zinc, copper, sodium, potassium was present. It is concluded that leaves of this plant is rich in nutritional components. Keywords--- Grewia tiliaefolia Vahl, Proximate analysis, Minerals, AOAC, Spectrophotometer. 
Polymorphisms of IL-4 Gene in Iraqi Behçet’s Disease Pat Israa Harjan Mohsen
Journal of Global Pharma Technology Volume 11 Issue 05.
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Abstract

The present research was carried out to reveal the correlation of IL-4 gene polymorphisms with Iraqi Behçet’s Disease patients. The technique that used in the present study is PCR-SSCP technique. DNA was extracted from blood. The results show that there was strong association between IL-4 gene and Behçet’s Disease there were two patterns (A and B), polymorphisms show significant differences(p>0.05) between patients and control where pattern (A) was occurred with percentage (2%) and (39%) while in the control and patients respectively .The pattern (B) was occurred with percentage (98% ) and (61%)  in the control and patients respectively .The results concluded that IL-4 gene polymorphisms were involved in  pathogenesis of Behçet’s Disease , our finding require more exploration to use this result as early hint of Behçet’s Disease  prevalence.Keywords: IL-4 .PCR-SSCP technique, Haplotypes, Polymorphisms, Behçet’s Disease 
A Comparative Study on In-vitro Nitric oxide scavenging activity between Zonegran and Levetiracetram Manish Babbu UG; Karthik V P
Journal of Global Pharma Technology Volume 12 Issue 09 (2020) Sept. 2020
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Abstract

Zonegran and Levetiracetram are two new range of anti-epileptics available in the market. Studies have been made earlier to demonstrate the antioxidant activity of the drugs Zonegran and Levetiracetam. Both have a good antioxidant property but there was not any comparative study for both the drugs. This study is to compare the anti-epileptic drugs Levetiracetam and Zonegran and demonstrate which drug has higher antioxidant property through Nitric Oxide radical scavenging activity.Methods: Nitric oxide scavenging activity was determined according to GriessIllosvoy reaction, with the help of Griess reagent. Ascorbic acid is used as positive control for the study. Conclusion: The study done suggests that both Zonegran and Levetiracetram possess antioxidant properties. At lower doses, Zonegran shows higher antioxidant potential over Levetiracetram and at higher doses, Levetiracetram shows slightly higher antioxidant property.
The Impact of the Plan and PDEODE Strategies in Developing Awareness of Cognitive Processes and Reducing Psychological Pollution Among Students of the Faculty of Physical Education and Sports Sciences Raed Abdulameer Abbas Al-Mashhadi
Journal of Global Pharma Technology .
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Abstract

The Research Aims toTo identify the psychological awareness of cognitive processes and pollution of the students of the Faculty of Physical Education and Sports Science.To know the impact of strategies and PDEODE in PLAN Transgender search.Any previous two strategies realized more development in the variables of the students.Use the descriptive approach in the method of normative studies and comparative studies in the measurement of psychological pollution and awareness of cognitive processes, and the experimental method of the two equal groups in the tribal and remote tests in the variable PLAN and PDEODE strategies. And select the community and the research sample students the second phase of the Faculty of Physical Education and Sports Science - University of Babylon in the academic year (2014-2015), was the number of educational units (28) units divided into 14 units at each strategy, by one lecture each week and the number of ( 7) topics for each variable, are executed in the order, and repeated to increase the absorption of interaction and students about the importance of topics in their lives, and after the use of statistical methods were reached conclusions:1.The arithmetic mean of the variables of research within the standard level when the moderate sample.2.The PLAN and PDEODE strategies have an effect on the two search variables.The PLAN strategy has a greater impact than the PDEODE strategy in developing awareness of cognitive processes and reducing psychological pollution among students.Keywords: Strategy PLAN, PDEODE strategy, awareness of cognitive processes, psychological pollution.
Investigation of Microbial Contamination Rates of Hospital Equipment and Nosocomial Infection in Different Wards of Two Public Hospitals in Sistan and Balouchestan Province during the First Six Months of 1394 (20 Mars - 20 September 2015) Zahra Ebrahimi Rigi Tanha
Journal of Global Pharma Technology Volume 08 Issue 07
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Abstract

Background and purpose: One way to hospital infection control, identify and determine Infection transmission tools that can be useful in the prevention. The purpose of this study was to determine the frequency and type of pollution instruments for 6 months in the treatment units. Material and method: This retrospective study was done from April to September 2014. Were taken 422 samples from disinfected  instruments. Laboratory personnel were sampling with sterile swab then cultured. If bacterial was growth and creating colony examined the type of bacteria. Collected data were analyzed with descriptive statistics. Results: The results showed gram-negative from 422 cultures were done 62 cases (14.69%) were positive. the microbial strains were 4 cases gram-negative (6.45%), 4 cases (70.96%) gram-positive and 14 cases (22.58%) mixture of fungi, gram-positive. The highest contamination was in bed 21 cases (33.86%). The highest contamination was in Surgical Ward 15 case (24.19%). Hospital infection rates in the first six months were three cases of 9600 admitted patients. Conclusion: These study findings was emphasize the importance and necessity of closer and deeper attention to the infection risk factors in order to reduce and control the nosocomial infection. Despite the principles cleaning and disinfection of surfaces are standard. Keywords: Microbial contamination of hospital equipment, Nosocomial infection, Microbial contamination of hospital wards.
Review on Nanosponge - A Contemporary Drug Delivery Approach Senthil Venkatachalam
Journal of Global Pharma Technology Volume 11 Issue 05 (2019) May 2019
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Abstract

An effective operational method of targeted drug delivery system has been an aim for the researchers in the pharmaceutical field for a prolonged time, but it has been mostly discouraged due to the complex chemistry behind in it and the difficulty in designing such a system, Nano sponges are such a delivery method using which targeted delivery to a specific site is possible and extensive researches are being done on nanosponges due to their such activity. Nanosponges as the name suggests are minute sponge like structures with size as small as a virus in which drugs can be incorporated into the voids. Studies have shown that these kind of formulations tends to circulate in the body until the targeted site is reached for the release and further it sticks at the site and releases the drug, since it can be modified to deliver the drug site specifically and hence can be more effective than other methods of delivery, another factor for consideration of nanosponges in targeted delivery is due to their good aqueous solubility which can be used to deliver drugs which are poorly solubleKeywords: Nanosponge, Cyclodextrin, Cross Linking, Functionalized Nanosponges.
Various Parameters Affecting to Production of Dried Jasminum sambac Flower Nguyen Phuoc Minh
Journal of Global Pharma Technology Volume 11 Issue 08 (2019) Aug. 2019
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Abstract

Jasminum sambac is one of the most cultivated species in Vietnam. The plant is much valued for its exquisitely fragrant flowers. Flowers of Jasminum sambac have been utilized as traditional medicines to treat many diseases. Objective of this study focused on on the effectiveness of different parameters of freeze-drying such as pressure (0.06, 0.08, 0.10, 0.12 mbar), primary drying temperature (-3oC, -5oC, -7oC, -9oC) and secondary temperature (26oC, 28oC, 30oC, 32oC) to the total phenolic (mg GAE/100 g) and total flavonoid (mg QE/100 g) of dried Jasminum sambac flower. At the end of drying process, we also monitored the stability of dried Jasminum sambac flower during 6 months of preservation. Our results showed that the optimal drying process should be conducted at 0.08 mbar, primary drying temperature -7oC, secondary temperature 28oC to achieve the best dried Jasminum sambac flower. From this production, shelf-life of dried Jasminum sambac flower could be last for 6 months without any deterioration.Keywords: Jasminum sambac, Dried flower, Freeze-drying, Total phenolic, Total flavonoid, Shelf-life, preservation.

Page 179 of 244 | Total Record : 2439

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