cover
Article Per Year (5 Year)
All
Home Page
OAI Link
Editorial Team
Contact
Reviewer
Google Scholar
Contact Name
I Wayan Sudarsa
Contact Email
sudarsa@unud.ac.id
Phone
-
Journal Mail Official
globalpharmatechnology@gmail.com
Editorial Address
India
Location
Kota denpasar,
Bali
INDONESIA
Journal of Global Pharma Technology
Published by Universitas Udayana
ISSN : 09758542     EISSN : -     DOI : -
Core Subject : Health,
Medicine & Pharmacology
ournal of Global Pharma Technology is a monthly, open access, Peer review journal of Pharmacy published by JGPT Journal publishes peer-reviewed original research papers, case reports and systematic reviews. The journal allows free access to its contents, which is likely to attract more readers and citations to articles published in JGPT. JGPT publishes original research work that contributes significantly to the scientific knowledge in pharmacy and pharmaceutical sciences- Pharmaceutics, Novel Drug Delivery, Pharmaceutical Technology, Cosmeticology, Biopharmaceutics and Pharmacokinetics, Pharmacognosy, Natural Product Research, Medicinal Chemistry, Computational Chemistry and Molecular Drug Design, Pharmaceutical Analysis, Pharmacology, Pharmacy Practice, Clinical and Hospital Pharmacy, Cell Biology, Genomics and Proteomics, Pharmacogenomics, Bioinformatics, Biotechnology and Applied Computer Technology. For this purpose we would like to ask you to contribute your excellent papers in pharmaceutical sciences.
Arjuna Subject : Kedokteran - Onkologi
Articles 2,439 Documents
 179   180   181   182   183 
Prevalence of Osteoporosis and Osteopenia in Iraqi Premenopausal and Postmenopausal Subjects among a Sample of Patients Attending Baghdad Teaching Hospital Ali Hussein Al-Hafidh
Journal of Global Pharma Technology .
Publisher : Journal of Global Pharma Technology

Show Abstract | Download Original | Original Source | Check in Google Scholar

Abstract

Back ground: Osteoporosis is a major public health problem and more common in women and older people Objective: to determine the prevalence of osteoporosis and osteopenia in premenopausal and postmenopausal subjects attending Baghdad teaching hospital  Methods: A cross sectional study was carried out for a period of one year in Baghdad teaching hospital Results:   A total of 240 subjects were included in this study, they were divided into 2 groups: the first group included 120 postmenopausal women with a mean age (59.93±6.88) and the second group included 120 premenopausal women with a mean age (46.36±4.07).Significant differences of bone mineral density of lumbar spine and both femurs between postmenopausal and premenopausal subjects. The percentage of osteoporosis and osteopenia in premenopausal was (26.7%) and (3.3%) respectively and in postmenopausal subjects was (34.17%) and (52.5%).T-score was used for postmenopausal subjects and Z-score for premenopausal subjects. The percentage of osteoporosis and osteopenia was higher in lumbar spine in both postmenopausal and premenopausal subjects than femurs. Normal BMD of right femur was higher than left femur in both postmenopausal and premenopausal subjects. Conclusion: The prevalence of osteoporosis and osteopenia in premenopausal was (26.7%) and (3.3%) and in postmenopausal subjects was (34.17%) and (52.5%) respectively. The percentage of osteoporosis and osteopenia was higher in lumbar spine in both postmenopausal and premenopausal subjects than femurs. Recommendations: Essential measures are needed for public education particularly dietary habit, lifestyle modification and widespread distribution of information about osteoporosis and its prevention.Keywords: Osteoporosis, Osteopenia, Postmenopausal, Premenopausal.
Nanocrystal Technology as a Tool for Improving Dissolution of Poorly Soluble Drugs Manar Adnan Tamer
Journal of Global Pharma Technology Volume 11 Issue 05.
Publisher : Journal of Global Pharma Technology

Show Abstract | Download Original | Original Source | Check in Google Scholar

Abstract

Many approaches have been developed over time to counter the bioavailability limitations of poorly soluble drugs. With advances in nanotechnology in recent decades, this issue has been approached through the formulation of drugs as nanocrystals. Nanocrystals consist of pure drug(s) and a minimum of surface active agent(s) required for stabilization. They are carrier-free submicron colloidal drug delivery systems with a mean particle size typically in the range of 200 - 500 nm. By reducing particle size to nanoscale, the surface area available for dissolution is increased, and thus bioavailability is enhanced. Drug nanocrystals constitute a versatile formulation approach to enhance the pharmacokinetic and pharmacodynamic properties of poorly soluble drugs. This enhancement is achieved by increasing the dissolution velocity, saturation solubility and mucoadhesion. However, stabilization of nanocrystals remains a major challenge in the development of nanocrystals. Main stability issues include increase in particle size, agglomeration, crystal transformation, and chemical instabilities. as such, combination of steric and ionic stabilizers are required for optimal stabilization. Nanocrystals can be administered by various routes including oral, parenteral, ocular, pulmonary and dermal routes with enhanced pharmacodynamic activity and safety. Functionalization of nanocrystals with radionuclide, imaging moieties and ligands further increases the versatility of nanocrystals. Nanocrystals has been proven successful, as demonstrated by the number of marketed drug products utilizing this technology. The present work provides an overview of the more recent achievements in improving the bioavailability of poorly soluble drugs according to their administration route, and describes the methods developed to overcome physicochemical and stability related problems.Keywords: Nanocrystals, Poorly soluble drug, Nanotechnology.
Pharmacological Study of Schiff Base Derived from Amoxicillin Drug and Vanillin Huda K. Khassaf
Journal of Global Pharma Technology Volume 12 Issue 06 (2020) June 2020
Publisher : Journal of Global Pharma Technology

Show Abstract | Download Original | Original Source | Check in Google Scholar

Abstract

Objective: Our present investigation is based on development and synthesis for new derivatives of amoxicillin as the wide use of this antibiotic led to serious medical problem of drugs resistance. Methods: Condensation of amoxicillin trihydrate with 4-Hydroxy-3-methoxy benzaldehyde yielded a novel Schiff base derivative of amoxicillin in good yield. Characterization of synthesized compound detected by IR and 1HNMR spectroscopy. The antibacterial activity of new compound was screened against the selected bacteria species Staphylococcus aureus, Escherichia coli, Bacillus cereus, and Klebsella pneumonia. The LD50 value was determinate by using up and down method. Results: Our obtained results for this antibiotic modulation method are within high acceptance criteria in vivo study determination of the toxic effect (LD50) of synthesized compound which was 477.2 mg / kg of body weight give a moderate value. Furthermore, in vitro study included antibacterial activity against some bacteria species of new compound was higher than the respective standard drug at tested doses level. Conclusion: Modulating amoxicillin drug can be used in the management of bacterial resistant disorders. Key words: Amoxicillin, Micro-organism species, Antibacterial activity, Disorders. Schiff-base.
The Effect of Cu-doping on the Optical Properties of ZnFe2O4 Films Prepared by Chemical Spray Pyrolysis Method Salim Azara Hussain
Journal of Global Pharma Technology .
Publisher : Journal of Global Pharma Technology

Show Abstract | Download Original | Original Source | Check in Google Scholar

Abstract

In this work, the effect of the copper doping on Optical properties of zinc Ferrite precipitated on the glass Substrate of quartz, with  ratios of Cu (x= 0,0.1,0.3,0.5,0.7,0.9) using the method of chemical spray Pyrolysis of thickness(300 ± 15nm) at a temperature (400 ± 10 oC) and annealing (520 oC) for range of (4h) the Optical properties have been identified of films wavelengths of (300-900) nm , it has been found that the energy gap before doping(2.86 eV) the energy gap increased to increase the proportion of doping the ratios (x=  0.1,0.3, 0.5) the energy gap at ratios (x= 0.7 ,0.9) also found that the highest value of the coefficient of absorption at the ratio (x=0 .9) and the value of(3x104).Keywords: Absorption factor, Optical conductivity, Energy gap, Deflection.
The Effect of the Managers’ Good Manners on Enhancing the Social Responsibility of the Staff from Agriculture Banks in Sistan and Baluchistan Mohammad Mostafa Dahmardeh
Journal of Global Pharma Technology Volume 08 Issue 02
Publisher : Journal of Global Pharma Technology

Show Abstract | Download Original | Original Source | Check in Google Scholar

Abstract

Efforts to improve human resource Responsibility and efficient use of human resources infinite, timeless way. In this way, ups and downs, one of the goals of efficiency, increase the desirability of life with all its dimensions. In this study, researchers are sought to The Effect of the Managers’ Good Manners on Enhancing the Social Responsibility of the Staff from Agriculture Banks in Sistan and Baluchistan. The research is descriptive and correlational. The target population included 419 Staff from Agriculture Banks in Sistan and Baluchistan. That uses Morgan table, 201 individuals were selected as sample. Library and field data collection for studies of Managers’ Good Manners questionnaire that standard questionnaire [1] and Social Responsibility questionnaire is self-made. Its validity and reliability have been approved. For data analysis using SPSS software, descriptive and inferential analysis (linear regression) is used. The results show that the Managers’ Good Manners and its components have an impact on Social Responsibility. 
Investigation of Star Gooseberry (Phyllanthus Acidus) Wine Production Nguyen Phuoc Minh
Journal of Global Pharma Technology Volume 11 Issue 01.
Publisher : Journal of Global Pharma Technology

Show Abstract | Download Original | Original Source | Check in Google Scholar

Abstract

The star gooseberry fruit is pendulous, bear in small clusters from the branches, round or slightly flattened at the poles. Gooseberry fruit is rich in antioxidants including ascorbic acid and phenolic compounds. It is an important herbal medicine due to its effective antiviral activities. Effect of primary fermentation temperature (26oC, 28oC, 30oC, 32oC), sugar to pulp ratio (4, 8, 12, 16% w/w), Saccharomyces cerevisiae inoculation (1.0 x 108,1.5 x 108, 2.0 x 108, 2.5 x 108 cfu/g) on ascorbic acid (mg/ 100 mL), total phenolic content (mg GAE/ 100 mL) and total flavonoid (mg CE/ 100 mL) content of Phyllanthus acidus wine were thoroughly investigated. The aging (1, 2, 3, 4 weeks) was also examined to improve the turbidity (mJ/cm2) and sensory score of wine. The optimal conditions for fermentation of Phyllanthus acidus juice should be conducted at 12 days of primary fermentation with 12% of sugar supplementation inoculated with 2.0 x 108 cfu/ml of Saccharomyces cerevisiae and 4 weeks of aging to get pleasant physico-chemical characteristics of Phyllanthus acidus wine. Phyllanthus acidus wine was red-pink, clear and transparent. This present study revealed that horticulture farmers would get more added values from Phyllanthus acidus fruits not only by local commerce but also processing. It could be processed by fermentation and conversion into high valued wine.Keywords: Phyllanthus acidus, Wine, Fermentation, Sacchromyces cerevisiae, Ascorbic acid, Phenolic, flavonoid.
Assessment of Noise Pollution and its Impact on Human Health in Hilla City Haydder Radhi Kadhim
Journal of Global Pharma Technology Volume 11 Issue 07
Publisher : Journal of Global Pharma Technology

Show Abstract | Download Original | Original Source | Check in Google Scholar

Abstract

Noise pollution is type of air pollution, it is unwanted sounds that reduce quality of person life via effect on normal activity like. It can disturb sleep, cause cardiovascular and psychophysiological effects, Material and method level of noise measured in five types of regions in hilla city during each season of year in two reading (morning and evening) with outside and inside building, then  comparative the results with international and local level of sounds, in addition to estimate effect it on human healthy. This work is down by using a precision sound level meter digital instrument as noise meter. Result this study showed that some selected regions of hilla city were over normal level of sounds which make this regions suffered of noise pollution Conclusion this noise may be pollution lead to effects on physiological and psychological state of human.
Identification of Echinococcus Granulosus Genotype in Iraqi's Sheep by Using Nd1 Gene MJ Muhaidi
Journal of Global Pharma Technology Volume 10 Issue 07: (2018) July 2018
Publisher : Journal of Global Pharma Technology

Show Abstract | Download Original | Original Source | Check in Google Scholar

Abstract

Hydatid Cysts were obtained from 15 sheep from hepatic, pulmonary, spleen, heart, and peritoneal cavity, between December 2014 and October 2015. Hydatid cysts (protoscoleces) were used for DNA extraction by using mechanical grinder. The purification of mt DNA was done by (promega kit, USA). The mitochondrial NADH dehydrogenase subunit 1 (ND1) genes was applied as aim for amplification by using polymerase chain reaction (PCR), all of 15 hydatid cysts yielded amplification products.PCR product for NADH1 800 bp. The PCR products had been purified and fractional sequences were produced. The sequences obtained were found to align with corresponding region for ND1 gene in the Gene Bank nucleotide database confirming to genotype of sheep strain (G1) in Iraq, Phylogenetic dissection of fractional sequence datum from ND1 gene for obtained Phylogenetic tree. G1 genotype was the majority widespread taxon and the genuine provenance of infection for Iraqi’s sheep. All of 15 specimens were G1 strain (sheep strain) according to the fractional sequences of NADH dehydrogenase 1 (ND1).Keywords: G1 strain, Hydatid cyst, ND1 gene, sheep, Sequences.
Need for Non-Drug Treatment for Alzheimer's Disease Mainul Haque
Journal of Global Pharma Technology Volume 09 Issue 12
Publisher : Journal of Global Pharma Technology

Show Abstract | Download Original | Original Source | Check in Google Scholar

Abstract

Need for Non-Drug Treatment for Alzheimer's Disease
Investigation of Sugar Concentration and Lactobacillus acidophilus Inoculation on Pickled Turmeric Rhizome Production Minh Phuoc Nguyen
Journal of Global Pharma Technology Volume 12 Issue 01
Publisher : Journal of Global Pharma Technology

Show Abstract | Download Original | Original Source | Check in Google Scholar

Abstract

Curcuma longa which is the source of the spice turmeric having different phytochemical constituents, and pharmacological activities. An alternative way of preserving surplus turmeric rhizomes could be fermented to pickle products. Preservation of the turmeric rhizomes by fermentation can eliminate the undesired taste and improve flavor of this herb. Different technical parameters such as sugar addition (1.5%, 2.0%, 2.5%, 3.0%, 3.5%) and Lactobacillus acidophilus (0.1%, 0.2%, 0.3%, 0.4%, 0.5%) affecting to the pickling process were examined. Our results revealed that 3.0% sugar, 0.3% Lactobacillus acidophilus (1010 cfu/g) as starter culture were adequate for lactic fermentation. The consumption of pickled turmeric rhizomes helps enhance balanced human nutrition. Lactic acid fermentation retains all the natural plant ingredients while improving the quality, taste and aroma. The benefits of pickled turmeric have been better understood in terms of high content of valuable curcumin. It becomes an important phytochemical source for human health. Production of pickle from this herb can help increase added values and reduce post-harvest losses.Keywords: Turmeric rhizome, Lactobacillus acidophilus, Pickled, Fermentation, Starter culture, Sugar.

Page 181 of 244 | Total Record : 2439

 179   180   181   182   183 

Filter by Year

2010 2026


Reset
Filter By Issues
All Issue Volume 18 Issue 01 (2026) Jan. 2026 Volume 17 Issue 12 (2025) Dec. 2025 Volume 17 Issue 11 (2025) Nov.2025 Volume 17 Issue 10 (2025) Oct. 2025 Volume 17 Issue 04 (2025) April 2025 Volume 17 Issue 03 (2025) March 2025 Volume 17 Issue 02 (2025) Feb. 2025 Volume 17 Issue 01 (2025) Jan 2025 Volume 16 Issue 12 (2024) Dec. 2024 Volume 16 Issue 11 (2024) November 2024 Volume 16 Issue 10 (2024) October 2024 Volume 16 Issue 09 (2024) September 2024 Volume 16 Issue 08 (2024) August 2024 Volume 16 Issue 07 (2024) July 2024 Volume 16 Issue 06 (2024) June 2024 Volume 16 Issue 05 (2024) May 2024 Volume 16 Issue 04 (2024) April 2024 Volume 16 Issue 03 (2024) March 2024 Volume 16 Issue 02 (2024) February 2024 Volume 16 Issue 01 (2024) January 2024 Volume 14 Issue 05 (2022) May 2022 Volume 13 Issue 05 (2021) May 2021 Volume 13 Issue 04 (2021) April 2021 Volume 13 Issue 03 (2021) March 2021 Volume 13 Issue 02 (2021) Feb. 2021 Volume 13 Issue 01 (2021) Jan. 2021 Volume 12 Issue 12 (2020) Dec. 2020 Volume 12 Issue 11 (2020) Nov. 2020 Volume 12 Issue 10 (2020) Oct. 2020 Volume 12 Issue 09 (2020) Sept. 2020 Volume 12 Issue 08 (2020) Aug. 2020 Volume 12 Issue 07 (2020) July 2020 Volume 12 Issue 06 (2020) June 2020 Volume 12 Issue 05 (2020) May 2020 Volume 12 Issue 04 (2020) April 2020 Volume 12 Issue 03 (2020) March 2020 Volume 12 Issue 02 (2020) Feb. 2020 Volume 12 Issue 01 (2020) Jan. 2020 Volume 12 Issue 08 Volume 11 Issue 12 (2019) December 2019 Volume 11 Issue 11 (2019) November 2019 Volume 11 Issue 10 (2019) October 2019 Volume 11 Issue 09: (2019) September 2019 Volume 11 Issue 09 (2019) September 2019 Volume 11 Issue 08 (2019) Aug. 2019 Volume 11 Issue 07 (2019) July 2019 Volume 11 Issue 06 (2019) June 2019 Volume 11 Issue 05 (2019) May 2019 Volume 11 Issue 04 (2019) April 2019 Volume 11 Issue 03 (2019) March. 2019 Volume 11 Issue 02 (2019) Feb. 2019 Volume 11 Issue 01 (2019) Jan. 2019 Volume 11 Issue 2: 2019 Volume 10 Issue 12. Volume 11 Issue 6. Volume 10 Issue 12 (2018) December 2018 Volume 10 Issue 11 (2018) November 2018 Volume 10 Issue 10 (2018) October 2018 Volume 10 Issue 09: (2018) September 2018 Volume 10 Issue 08: (2018) August 2018 Volume 10 Issue 07: (2018) July 2018 Volume 10 Issue 06: (2018) June 2018 Volume 10 Issue 05: (2018) May2018 Volume 10 Issue 04: (2018) April 2018 Volume 10 Issue 02: (2018) Feb 2018 Volume 10 Issue 01: (2018) Jan. 2018 Volume 10 Issue 10: 2018 Volume 10 Issue 01 Volume 09 Issue 12 Volume 09 Issue 11 Volume 9 Issue 11 . Vol. 9 Issue 7 : 2017 Volume 9 Issue 10 Volume 09 Issue 09 Volume 09 Issue 08 Volume 9 Issue 07 Volume 09 Issue 05 Volume 09 Issue 04 Volume 09 Issue 03 Volume 09 Issue 02 Volume 08 Issue 11 Volume 08 Issue 07 Volume 08 Issue 06 Volume 08 Issue 05 Volume 08 Issue 04 Volume 08 Issue 03 Volume 08 Issue 02 Volume 08 Issue 01 Volume. 9 Issue 6 Volume 08 Issue 10: (2016) October 2016 Volume 08 Issue 09: (2016) September 2016 Volume 12 Issue 01 Volume 11 Issue 07 Volume 11 Issue 05. Volume 11 Issue 04. Volume 11 Issue 03 Volume 11 Issue 01. Volume 08 Issue 08 Volume 04 Issue 02: (2012) February 2012 Volume 03 Issue 06: (2011) June 2011 Volume 03 Issue 04: (2011) April 2011 Volume 02 Issue 10: (2010) Oct.2010 Volume 02 Issue 07: (2010) July 2010 Volume 02 Issue 05: (2010) May 2010 Volume 02 Issue 03: (2010) March 2010 More Issue