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Journal of Global Pharma Technology
Published by Universitas Udayana
ISSN : 09758542     EISSN : -     DOI : -
Core Subject : Health,
Medicine & Pharmacology
ournal of Global Pharma Technology is a monthly, open access, Peer review journal of Pharmacy published by JGPT Journal publishes peer-reviewed original research papers, case reports and systematic reviews. The journal allows free access to its contents, which is likely to attract more readers and citations to articles published in JGPT. JGPT publishes original research work that contributes significantly to the scientific knowledge in pharmacy and pharmaceutical sciences- Pharmaceutics, Novel Drug Delivery, Pharmaceutical Technology, Cosmeticology, Biopharmaceutics and Pharmacokinetics, Pharmacognosy, Natural Product Research, Medicinal Chemistry, Computational Chemistry and Molecular Drug Design, Pharmaceutical Analysis, Pharmacology, Pharmacy Practice, Clinical and Hospital Pharmacy, Cell Biology, Genomics and Proteomics, Pharmacogenomics, Bioinformatics, Biotechnology and Applied Computer Technology. For this purpose we would like to ask you to contribute your excellent papers in pharmaceutical sciences.
Arjuna Subject : Kedokteran - Onkologi
Articles 2,439 Documents
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The Effects of Team-Orientation of the Organizations on the Increase in Organizational learning and Management Effectiveness (Case Study: Maskan Bank, West Azarbaijan Province) Parivash Mohammadi Gheshlagh
Journal of Global Pharma Technology Volume 08 Issue 09: (2016) September 2016
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Abstract

This study aims to investigate the effects of team-orientation of the organizations on the increase in organizational learning and management effectiveness of the staff worked in the Maskan Bank in West Azarbaijan Province. The population of this study included the staff of Maskan Banks in West Azarbaijan Province (322 staff). The sample size was estimated equal to 175 staff by the use of Cochran formula and stratified random sampling method. Data collection tools were the standard team-orientation inventory, standard organizational learning inventory and standard management effectiveness inventory which were used after investigating their validities and reliabilities. Their reliabilities were estimated equal to 0.849. The inventories were collected and the obtained data was classified and analyzed by the use of descriptive and inferential statistics (path analysis with SPSS software and Amos software). The results of path analysis showed that the dimensions of organization’s team-orientation indirectly affect the management effectiveness through the increased organizational learning in Maskan Bank in West Azarbaijan Province.Key words: organization’s team-orientation, management effectiveness, organizational learning
Phenotypic, Genotypic Correlation and Path Coefficient for Several Traits of Maize Under Watered and Water Stress Banan H. Hadi
Journal of Global Pharma Technology Volume 11 Issue 2: 2019
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Abstract

In order to determine the best selection criteria to improve the grain yield of maize for synthetic cultivar, Ibaa 5012 under watered and water stress treatment (5 and 10 days interval), an experiment was conducted in the field of Crop Science Dept. College of Agriculture-University of Baghdad, during two seasons, spring and fall in 2013, using Randomized complete block design with four replications. The genetic, phenotypic, environment and path coefficient were estimated for ear length, no. of rows, no. of grains row-1, no. of grains plant-1, grain weight, no. of ears plant-1, root weight, water use efficiency and grain yield. The results showed that the grain weight was highly positive, genetic (0.9735), phenotypic (0.9714) environment (0.9552) correlated with grain yield, and was positively correlated with other traits such as ear length (0.8445, o.7216), no. of rows (0.8918, 0.8141), no. of grain row-1 (0.9068, 0.8554), water use efficiency (0.6867, 6452) and root weight (0.5068, 0.4369), due to high direct positive effect in the grain yield (1.0576), in spring season irrigation treatment, the correlations in the water stress treatment were the no. of grains plant-1 with the yield at the genetic, phenotypic and environment level (0.8912, 0.8966,0.9435) respectively, due to high positive direct effect (0.7459). In fall season, irrigation treatment, the genetic, phenotypic, and environmental high and positive correlations were for trait no. of grain plant also (0.9344, 0.9179, 0.7510) respectively, and the value of positive direct effect was (0.8498). In water stress treatment, the high positive direct effect was for no. of grains plant-1 too (0.5458) due to high positive genetic, phenotypic and environment correlations with yield (0.8470, 0.8497, 0.9346) respectively, and it have high positive correlations with most other traits. It can be concluding that the grain weight and no. of grains plant-1 best selection criteria to improve the yield of maize population.Keywords: Maize, Yield, Direct effect, Genetic correlation, Water use efficiency.
Knowledge and Determinants of Use of Health Supplements among Undergraduates in Ipoh, Perak Malaysia Sook Ching Chan
Journal of Global Pharma Technology Volume 11 Issue 08 (2019) Aug. 2019
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Abstract

Background Objectives: Research on health supplement usage among Malaysian undergraduate students is still limited although an average of USD17.30 was reported spent for nutritional supplements monthly.This study aimed to determine the usage of health supplements among the undergraduate students in Ipoh, Perak, Malaysia and the relationship between consumption and knowledge of health supplement among these students. Methods: This cross-sectional study was conducted in March to April 2018. Health sciences students and non-health sciences students from four different universities/colleges were selected through cluster sampling and random sampling method. A questionnaire that included socio-demographic data, lifestyle practices, usage of health supplement and assessment of knowledge of health supplements was given to selected students. Data analysis was done using SPSS 22.0 (Trial Version).Results: There were 374 respondents of which 79 students (21%) consumed health supplements. The majority of those who consumed health supplements (82%) were from Health Sciences, female (61%), overweight (44%) and with family income of more than RM5000 (39%). The top three most common reasons for using health supplements were “to maintain good health” (82.3%), “to ensure adequate nutrition” (54.4%) and “to improve immune function” (40.5%). The most common types of health supplements used were vitamins (44%) and minerals (23%).  Fifty seven percent of the consumers had good knowledge compared to 30.5% of non - consumers. Conclusion: The majority of the consumers were from Health Sciences, female, overweight, had family income more than RM5000 and had better knowledge regarding the health supplements as compared to the non-consumers.Keywords: Health supplements, Undergraduates, Knowledge, Use.
Solid-phase Reactor with Immobilized Lead Dioxide for Flow Injection-Spectrophotometric Determination of Naringenin in Supplement Formulations Israa M. Jawad Al-mashhadani
Journal of Global Pharma Technology Volume 10 Issue 06: (2018) June 2018
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Abstract

This study includes a simple and economic method for sensitive determine of naringenin (NAR) in (pure and supplements). The determination method depends on the oxidative coupling reaction between N, N-dimethyl-p- phenylenediamine with NAR in the present of PbO2 immobilized on cellulose acetate matrix. The reaction was carried out in alkaline medium, to form blue color product has maximum  absorbance at wavelength of 596 nm. The experimental variables of solid phase reactor and flow injection parameters were investigated and optimized. Beer's law obeyed over NAR concentration range from 0.5 to 60 µg mL-1 with a sample throughput of 44 samples per hour.  The solid phase material showed good stability, the relative standard deviation was 2.786 for 38 injections. The proposed method was successful for NAR determinate in supplements capsules.Keywords: Naringenin, N, N-dimethyl-p-phenylenediamine, Immobilized lead dioxide, Solid phase rector, Flow injection determination.
The Relationship between the Aquatic Extracts of the Moringa Oleifera Seeds and the Genetic Expression of (SAP5) Gene in Candida albicans Accompanying Cancer Patients Majid kadhim Aboud Alshibly
Journal of Global Pharma Technology Volume 9 Issue 10
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Abstract

It has been detected gene expression using the Real – time technique for some Isolations Candida albicans before and during infection to cells epithelium, Ther esults be  high rate of gene expression (37.156 ±7.66049) to T2 treatment  and significantly difference at the level of the probability P ≤ 0.01 ,compared with the C treatment  that at a rate(1.040 ± 0.32229).As the use of an extract of the seeds of Moringa Oleifera In the concentration of 25% to assess its impact on the gene expression (SAP5) before and during infection yeast cells of epithelial and the results were reduced gene expression treatment T1 at a rate(0.074 ± 0.01542) comparison with the treatment C (1.040 ± 0.32229) and teams significantly at the level of the probability P ≤ 0.01, As for the T2 treatment was gene expression at a rate(37.156 ±7.66049) high Compared with T3 treatment in which gene expression dropped at a rate (19.565 ± 8.82162) and with a significant difference at the level of the probability of P ≤ 0.01. Keywords:  Moringa Oleifera, SAP5gene, C.albicans, Candidiasis, Real-time PCR.
Optimization the Mathematical and Computational Approaches to Understanding the Medical Science Applications Ali Jalal Ali
Journal of Global Pharma Technology Volume 10 Issue 09: (2018) September 2018
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Abstract

Computing is the backbone of modern healthcare systems, it not only cut-downs the associated treatment and medicine costs but also decreases the logistics requirements simple mathematics is used effectively by people in all walks of life to assist decision making. However, in this paper it is argued that many, so called, applied mathematicians affiliated with university mathematics departments all too often do not apply mathematics to anything in particular. Although there is the national appeal of relevance to an application for the equations under study, applied mathematics has come to mean something completely different than really applying mathematics to solve an important the problem in another discipline. Even ‘mathematical modeling’ is often observed to involve the development of ‘neat’ equations which are stated to be loosely linked to something people will care about but is presented with esoteric and obscure mathematics which is not accessible to stakeholders in the application of the problem. It is suggested that simple models that directly answer questions of relevance are always better than complex models that are not influential, unrealistic, or irrelevant and that experts in the area of application must have integral roles in the entire modeling process, including the design of research questions, ensuring realism of model structures, informing parameter estimates, and the presentation and communication of results.Keywords: Computing, Medical Applications, Medical Image, Polynomials.
Clinical Applications of Doppler Ultrasound in Obstetrics Rowshan Jawad Azeez
Journal of Global Pharma Technology Volume 11 Issue 04.
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Abstract

Ultrasound images of flow, whether color flow or spectral Doppler, are essentially obtained from measurements of movement. In ultrasound scanners, a series of pulses is transmitted to detect movement of blood. Echoes from stationary tissue are the same from pulse to pulse. Echoes from moving scatters exhibit slight differences in the time for the signal to be returned to the receiver. These differences can be measured as a direct time difference or, more usually, in terms of a phase shift from which the ‘Doppler frequency’ is obtained. They are then processed to produce either a color flow display or a Doppler sonogram.
Effects of DHA-Enriched Fish Oil Supplements on Dopamine Receptor Gene Expression in the Cerebral Cortex and Hippocampus Related to the Male Rat’s Weight Gain Fifi Veronica
Journal of Global Pharma Technology Volume 12 Issue 06 (2020) June 2020
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Abstract

Background: Docosahexaenoic acid (DHA) can penetrate through the barrier between the blood and the brain through simple diffusion and obtains benefits for neurons. Supplementation of DHA-enriched fish oil for seven weeks in young male Wistar rat could alter dopamine (DA) receptor modulation, and it may be related to the increased weight gain. Aim: This present study aims to explore the alteration of the dopamine receptors (D1DR and D2DR) gene expression in the cerebral cortex and hippocampal area, as a top-down circuit control, related to the role of body weight gain as an indicator of food intake. Methods: Twenty samples of Rattus novergicus, aged 7-8 weeks, were randomly grouped into two groups as follows: 10 rats as the control group (CG) and 10 rats in the group that received treatment with fish oil -omega 3 capsules (FOG). CG and FOG were fed with standard laboratory food and received water ad libitum. The treated group (FOG) received 0.2 ml added supplementation of DHA-enrich fish oil (FO) capsules with the daily dose of 30 mg EPA and 45 mg of DHA for 7 weeks via gavage every morning. The body weight of each rat was weighed and recorded every 2 weeks. Results: The weight had increased significantly in the FOG during the first 4 weeks of treatment and continued to grow until the end of the 7 weeks of treatment (p=0.036). The relative D1DR gene expression in the cerebral cortex was significantly higher compared to the relative expression mRNA in the hippocampus region (D1DR 1.6 fold, p
Biosynthesis, Characterization and Antibacterial effect of Zno Nanoparticles Synthesized by Lactobacillus Spp Jehan Abdul Sattar Salman
Journal of Global Pharma Technology .
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Abstract

Biosynthesis of Zinc oxide (ZnO) nanoparticles using a probiotics bacteria Lactobacillus spp. which isolated from different sources was studied. The formation of ZnO nanoparticles was checked using X-ray diffraction (XRD) technique, Atomic Force Microscopy (AFM), Fourier Transform Infrared Spectroscopy (FTIR), Scanning Electron Microscopic (SEM) and Energy-dispersive X-ray analysis (EDX) spectra. The characterization results showed that the biosynthesized nanoparticles are hexagonal ZnO crystal structure, spherically shaped with a diameter of about (30.3 - 38) nm. The antibacterial effect of the synthesized ZnO nanoparticles was determined through the minimum inhibitory concentration (MIC) against pathogenic bacteria isolated from skin infections included Pseudomonas aeruginosa, Acinetobacter baumanii, Klebsiella pneumonia , and Staphylococcus aureus. The synthesized ZnO nanoparticles were effective against all the tested pathogenic bacteria at different degrees. The best effect has been shown against A. baumannii with MIC recorded at 12.5mg/ml, but the lowest effect has been recorded on P. aeruginosa(50mg/ml).Keywords: Biosynthesis, ZnO nanoparticles, Lactobacillus spp., Antibacterial activity, Skin infections.
An Overview: The Treatment of Tuberculosis Nitin kumar
Journal of Global Pharma Technology Volume 09 Issue 03
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Abstract

Tuberculosis is an infectious disease which is caused by bacteria. Tuberculosis most commonly affects the lungs, but it can also affect any other organ. The infection doesn`t always result in disease. The human immune defense cells can check and control pathogens, so that progression to disease only occurs in about 10% of adults. However the infection may remain latent and can reactive at any time, also after decades if e.g. the immune system is weakened. If left untreated, tuberculosis is a life-threatening illness. The main burden of tuberculosis is carried by developing countries. The cases of tuberculosis have been declining in Germany for years. But the global increase of tuberculosis affects every region of the world, also developed countries. In the early 1940s and 1950s, tuberculosis (TB) was the number one cause of death. Patients with TB were admitted to the many sanatoria we had in various parts of the country and were often managed by surgical means. TB chemotherapy became available only in the late 1950s. At this time, TB was already a major cause of morbidity and mortality. Realizing its seriousness, the Malaysian government launched its National TB Control Programme (NTP) in 1961. Multi-drug-resistant tuberculosis (MDR-TB) is defined as tuberculosis that is resistant to at least isoniazid and rifampicin: the two most powerful first-line treatment anti-TB drugs. This type of drug resistance, called acquired drug resistance, occurs in TB because a patient’s bacterial population survives for several months during treatment.  Keywords: Drug-resistant, Mycobacterium tuberculosis, Ethambutol.

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