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Journal of Global Pharma Technology
Published by Universitas Udayana
ISSN : 09758542     EISSN : -     DOI : -
Core Subject : Health,
Medicine & Pharmacology
ournal of Global Pharma Technology is a monthly, open access, Peer review journal of Pharmacy published by JGPT Journal publishes peer-reviewed original research papers, case reports and systematic reviews. The journal allows free access to its contents, which is likely to attract more readers and citations to articles published in JGPT. JGPT publishes original research work that contributes significantly to the scientific knowledge in pharmacy and pharmaceutical sciences- Pharmaceutics, Novel Drug Delivery, Pharmaceutical Technology, Cosmeticology, Biopharmaceutics and Pharmacokinetics, Pharmacognosy, Natural Product Research, Medicinal Chemistry, Computational Chemistry and Molecular Drug Design, Pharmaceutical Analysis, Pharmacology, Pharmacy Practice, Clinical and Hospital Pharmacy, Cell Biology, Genomics and Proteomics, Pharmacogenomics, Bioinformatics, Biotechnology and Applied Computer Technology. For this purpose we would like to ask you to contribute your excellent papers in pharmaceutical sciences.
Arjuna Subject : Kedokteran - Onkologi
Articles 2,439 Documents
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Prediction of Scoring Skills from the Persistence of Basketball in Terms of Cognitive-kinetic Abilities of School Children Aged 11 Years Zahraa Ihsan Abd Aoun
Journal of Global Pharma Technology .
Publisher : Journal of Global Pharma Technology

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Abstract

The introduction and problem of research on childhood, which is one of the most important stages in human life, has been manifested by its great impact on its future life because it is the basis on which the rest of its life is built and through which the basic concepts are formed, as well as the proper planning of the educational and educational process because it Comprehensive studies of all aspects of the child involved (mental, motor, physical, emotional), where the growth of those aspects intersect, each one is affected by the other. Cognitive-kinetic abilities are the ones that the specialists sought to study and reveal their levels and the objective of the study was to:To recognize the level of cognitive-kinetic abilities and the skill of correction from the constant basketball of schoolchildren in the center of Kerbala Governorate aged 11 years.To identify the contribution ratios of cognitive-kinetic skills for the correction of the school attendance of schoolchildren in the center of Kerbala Governorate.Forecasting of the skill of the correction of a basketball constant in the meaning of cognitive-kinetic abilities of schoolchildren in the center of Kerbala Governorate.The researchers used the descriptive method of surveying and mutual studies (correlation and comparison), the researcher identified her research community for elementary school pupils in the center of Kerbala Governorate. The selection of her research sample was made with a simple random sampling method and (260 pupils), used Statistical pouch Researcher (SPSS).One of the most important conclusions:There are significant percentages of some cognitive - motor abilities in the skill of correction of the stability of basketball in primary school students.The development of predictive equations for the skill of correction of the stability of the basketball in terms of cognitive abilities - kinetic to elementary school pupil's model.Keywords: Prediction, Scoring skills, Cognitive-kinetic abilities and schoolchildren.
The Age Aspect of Etiopathogenetic and Clinico-morphological Features of Chronic Gastritis Anna Berestova
Journal of Global Pharma Technology Volume 11 Issue 6.
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Abstract

Chronic gastritis (CG) is a histopathologic entity characterized by chronic inflammation of the gastric mucosa with loss of gastric glandular cells. CG, pathological regeneration of the gastric mucosa, intestinal metaplasia (IM), and intraepithelial neoplasia or epithelial dysplasia (ED) of the stomach are common and are associated with an increased risk of gastric cancer. 800 patients (aged 8 to 80) were examined during the period of 2012-2017. Patients with CAG were diagnosed by endoscopy then underwent histological, bacteriological and cytological examinations. The Enzyme-Linked Immunosorbent Assay (ELISA) was used to detect antibodies to H+/K+ -ATPase and to Castle factors of parietal cells of the gastric mucosa in serum.Keywords: Helicobacter pylori (H. pylori) infection; Enzyme-Linked Immunosorbent Assay; gastric glandular cells.
A Review on Electrospun Nanofibres for Drug Delivery Kamala Kumari
Journal of Global Pharma Technology Volume 12 Issue 11 (2020) Nov. 2020
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Abstract

Electrospinning is most widely used technique for fabrication of nanofibres. It is cost effective, simple and versatile process. The resulting nanofibres possess unique properties such as a high surface-area-to-volume and aspect ratio, low density, and high pore volume. These properties make the nanomaterials more advantageous than conventional materials in energy harvesting, conversion, and storage devices. There are different aspects of electrospinning, but the current discussion is based on the use of electrospun fibrous matrices for drug delivery. The article explains about all the available approaches to incorporate drugs onto or within electrospun fibrous matrices, along with their release mechanisms and about the applications of such drug carrying fibrous matrices for regeneration of various tissues, such as neural, vascular, cardiac, skin, and bone.
Mixed Effects of Marketing with Approach of Information Technology for Promotion of Customer's Loyalty in Hamadan Province Clubs Ali Akbar Zohrevand
Journal of Global Pharma Technology .
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The present study is Descriptive method type study from its application essence and in consideration to its objective, that has been conducted in the form of survey research. Statistical population is all the users of sports gymnasiums in Hamadan province that according to report from sports insurance control is reported to be 1000.statisticalsample was predicted to be 382 based on Morgan table easement tool includes ( consists of) mixed local marketing glue stingier (1389) and technical information Questionnaire (1395) .validity and reliability was obtained to be 0.80 for mix marketing element and 0.91 for technical information Questionnaire respectively by using Cranach Alpha. To analyze the data’s, discretional and interferential. Statistics such as Kolmogorov - Simonov test (test k-s), one sample t test, and freedman test was used. the results of this study showed that, there is a significant difference between the observed and imaginary average’s in mixed marketing elements ( t= 29/12 , p<0/001) .in the other word , situation of mixed marketing elements in sample study is little bet term than assumed or imaginary elements. Freedman test results showed that, the highest ranking average is for employee’s elements (4.46) and the lowest ranking is for product (2.72). It is recommended that all of employees or staff in sport clubs achieve the required or necessary skills. In using the internet, and also know the applied software packages which are related to their work area and have a special skills in utilizing then.Keywords: mixed marketing, Information technology, Customer’s loyalty. Clubs in Hamadan province.
Synthesis and Characterization of Azo Dyes Ligands Complexes with Rh (III) and La (III) and Studies Their Industrial and Bacterial Application Amer. J. Jarad
Journal of Global Pharma Technology Volume 11 Issue 09: (2019) September 2019
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Abstract

1-[4-(2-Hydroxy-4, 6-dimethyl-phenylazo)-phenol]-ethanone (HL1) and 2-(4-methoxy-phenylazo)-3, 5-dimethyl-phenol (HL2) were produced by combination the diazonium salts of amines with 3, 5-dimethylphenol. The geometry of azo compounds was resolved on the basis of (C.H.N) analyses, 1H and 13CNMR, FT-IR and UV-Vis spectroscopic mechanisms. Complexes of La (III) and Rh (III) have been performed and depicted. The formation of complexes has been identified by using elemental analysis, FT-IR and UV-Vis spectroscopic process as well, conductivity molar quantifications. Nature of complexes produced have been studied obeyed mole ratio and continuous alteration ways, Beer's law followed through a concentration scope (1×10-4 - 3×10-4 M). High molar absorbtivity from the compound solutions were noticed. Analytical data showed that all the complexes offered 1:3 metal-ligand ratios. In the radix from physicochemical datum an octahedral structure was described of the complexes. Biological activity of these compounds was assayed. Other than, the dyeing carried out of the produced compounds was practical in cotton fabric. The dyes were checked into light and detergent firmness. Keywords: Complexes, Azo dyes, Biological activity, Acetophenone, Aniline.
Computational Analysis of MK2 Protein for HT Carcinoma Cells using Pre-Processing and Characterization Techniques for Cell Death/ Survival Shruti Jain
Journal of Global Pharma Technology Volume 10 Issue 11 (2018) November 2018
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This paper presents the computational analysis using pre-processing and different characterization of MK2 proteins for cell death/ survival for HT carcinoma cells. Initially data is collected which than pre processed by completing the missing data, removing various outliers, checking whether the data is normal or non- normal. Later various characterisation steps were applied which includes: classification, regression, clustering, association rules etc. Different data variables use different approaches of pre processing and characterisation. In this paper we have collected the different data of MK2 proteins where we have cleaned the data by using various clustering approaches, than regression analysis, correlation matrix and covariance matrixes are calculated. In last we have classified the data by using different machine learning approaches (k-NN, SVM and Neural network). For k-NN we have compared the results of different techniques like chebyshev, city block and Euclidean. For SVM we have used linear, polynomial, RBF and sigmoid function for both types (Type 1 and Type 2) and for neural network we have calculated training, test and validation perfection using different hidden, and output activation function. This paper shows best 10 network using MLP and RBF approach. 
POTENTIAL OF ASTAXANTHIN FROM ASIAN TIGER SHRIMP (Penaeus monodon) SHELL EXTRACT AS AN ANTIBACTERIAL AND ANT INFLAMATORY sukmawati syarif
Journal of Global Pharma Technology Volume 11 Issue 01.
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Abstract

Asian tiger shrimp (Penaeus monodon) shell is an industrial waste which becomes one of the sources of carotenoids in the form of astaxanthin (3.3’-dihydroxy-β, β′-carotene-4.4′-dione) which has a very potential biological activity because it can work on target molecules. Astaxanthin in Asian tiger shrimp shell is well known to be lipophilic, being insoluble in water but soluble in organic solvents, one of which acetonitrile. The characteristics of astaxanthin were obtained through qualitative and quantitative analyses using FTIR (Fourier Transform Infra-Red) and HPLC (High Performance Liquid Chromatography). Furthermore, antibacterial and anti-inflammatory activities had been tested. Based on the research results done on the inhibition of Asian tiger shrimp (Penaeus monodon ) shell extract on the 5th growth of the test bacteria, the tiger shrimp shell extract had antibacterial activity on Eschericia coli., Streptococcus mutans, Pseudomans auriginosa, Salmonella typhi, Staphylococcus aureus which was characterized by the presence of clear zone / inhibition zone / Oligodynamic zone which showed the effect of tiger shrimp shell extract in killing and inhibiting the growth of test bacteria. Besides, An anti-inflammatory testing through extracting chemical components with acetonitrile solvent with several concentrations showed that the anti-inflammatory activity with a concentration of 1000 ppm with % stability on erythrocyte membrane obtained 60.516%, indicating that the higher the concentration used, the better was the anti-inflammatory effect.
Synthesis, Characterization and Bioactivity Study of Mixed-ligand Complexes with Some Metal ions for new dithiocarbamate, 8-Hydroxyl quinolone Lekaa M. Hadi
Journal of Global Pharma Technology Volume 12 Issue 01
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A series of  [M(Q)(L)] (where M=Co(II),Ni(II) ,Cu(II), Zn(ll),Cd(ll) and Pd(II) , Q=8-hydroxylquinoline and L= dithiocarbamate ligand) complexes have been  prepared. The new dithiocarbamate compound was characterized using elemental analyses, FT-IR, UV-VIS spectroscopy magnetic moments, 1H and 13C NMR for ligands, thermal gravimetric analysis (TGA), differential thermal gravimetric (DTG). The antibacterial activities of synthesized compound were studied against Esherichia Coli, Staphylococcus aureus, Proteus mirabilis and Pseudomons aerugino, for antifungal activity against Candida albicans and Candida tropicalisKeywords: Mixed ligand complexes, Dithiocarbamate, Spectral dat.
Evaluation of Hirschsprung’s Disease in a Pediatric Hospital in Southern Iran During 2005-2013 Farzaneh Dehghan
Journal of Global Pharma Technology .
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Background: Hirschsprung’s disease (HD) is a congenital absence of ganglion cells in the lining of the large intestine that can cause functional intestinal obstruction. Objective: The aim of this study was to investigate the incidence of Hirschsprung's disease in patients referring to a pediatric hospital in south of Iran over a period of 9 years. Methods: This retrospective research was carried out on all neonates, infants and children who referred to the largest pediatric Hospital of Hormozgan in Bandar Abbas, Southern of Iran due to suspected signs and symptoms of hirschsprung’s disease during the 9 years from March, 2005 to March, 2013.Demographic data and clinical symptoms of these patients were extracted from medical records available in hospital archives by a checklist. Results: Among the 85177 hospitalized patients in koodakan hospital of Bandar Abbas, a total of 425 cases had Hirschsprung’s disease (HD) with an overall male-to-female incidence ratio of 1.72. An overall increasing trend was observed in studied time. Chronic constipation (92.2%) and abdominal distension (91.1%) were the most common complaints. There were 21 deaths (4.9%) in cases with HD but none of the deaths in this population were attributable to HD. Conclusions: Based on the result the incidence of hirschsprung’s disease was elevated in recent years. However, more studies in several provinces are required to determine the exact value of incidence and further associations.Keywords: Hirschsprung’s disease, neonates, infants, children
Synthesis new Trifluoperazine Selective Liquid Electrodes Depending on Molecularly Imprinted Polymers Based on PVC Membrane for Determination of Trifluoperazine from Pharmaceutical Samples Ahmed Mohsen Dhari
Journal of Global Pharma Technology .
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Liquid electrodes of polymers imprinted with Trifluoperazine were synthesized based on Mechanics polymerization of precipitation. The molecularly imprinted polymer (MIP) and non-imprinted polymers (NIP) It was manufactured using (TFP) as a template. In polymerization process, 2-Hydroxy ethyl meth acrylate (2-HEMA) and 2-Vinyl Pyridine (2-VP) were used as monomers.  Divinylbanzene (DVB) was used as cross-linkers and benzoyl peroxide (BPO) as an initiator. The molecularly imprinted membranes and the molecularly non-imprinted membranes were synthesized utilize DibutylSebacate (DBS) and Nitro benzene (NB) as plasticizers in PVC matrix.  Detection limit and Slopes of the liquid electrodes are ranged at (3 × 10-6– 8 × 10-6) M and (21.83– 23.03) mV/decade, respectively. Response time was 60 seconds. The electrodes were filled with liquid of 10-1 M standard solution of drug and observed stable response for a pH ranged from 1.5 to 12 and with good selectivity for more than several types. The new synthesis electrodes were successfully used for the analyte estimated in preparation pharmaceutical sample without any time consuming pretreatment steps.Keywords: Molecularly imprinted electrodes; Trifluoperazine; Potentiometric method; (2-HEMA); (2-VP) monomers

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