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Journal of Global Pharma Technology
Published by Universitas Udayana
ISSN : 09758542     EISSN : -     DOI : -
Core Subject : Health,
Medicine & Pharmacology
ournal of Global Pharma Technology is a monthly, open access, Peer review journal of Pharmacy published by JGPT Journal publishes peer-reviewed original research papers, case reports and systematic reviews. The journal allows free access to its contents, which is likely to attract more readers and citations to articles published in JGPT. JGPT publishes original research work that contributes significantly to the scientific knowledge in pharmacy and pharmaceutical sciences- Pharmaceutics, Novel Drug Delivery, Pharmaceutical Technology, Cosmeticology, Biopharmaceutics and Pharmacokinetics, Pharmacognosy, Natural Product Research, Medicinal Chemistry, Computational Chemistry and Molecular Drug Design, Pharmaceutical Analysis, Pharmacology, Pharmacy Practice, Clinical and Hospital Pharmacy, Cell Biology, Genomics and Proteomics, Pharmacogenomics, Bioinformatics, Biotechnology and Applied Computer Technology. For this purpose we would like to ask you to contribute your excellent papers in pharmaceutical sciences.
Arjuna Subject : Kedokteran - Onkologi
Articles 2,439 Documents
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Experimental Research On The Development Of Extemporaneous Ointment ForThe Treatment Of Proctologic Diseases Pul-Luzan V.V.
Journal of Global Pharma Technology Volume 12 Issue 01
Publisher : Journal of Global Pharma Technology

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Abstract

Hemorrhoids are the most common proctological diseases affecting an average of 12 people out of 100. Hemorrhoid affects more than 10 % of the adult population of the planet, and the proportion of the total number of proctological diseases is 40 %. Hemorrhoid is the most common reason to see a proctologist. Therefore, the problem of choosing the tactics of treatment of this category of patients remains relevant. If constipation is called “intellectual disease”, then hemorrhoid is called “royal disease”. Men and women suffer from this disease equally. In women, exacerbation of hemorrhoid often occurs during pregnancy, usually in the last trimester. Sooner or later, enlargement of the hemorrhoid appears in most people.The objective of this work is the development of extemporaneous ointment for the treatment of proctologic diseases. To achieve this goal the following tasks were solved: the literature on the current state of such diseases as hemorrhoids has been analyzed and summarized; the range of medicines used to treat hemorrhoids has been analyzed. As a result the composition of the combined ointment for the treatment of hemorrhoid has been substantiated and its technology has been developed, the stability and microbiological purity of the created extemporaneous combined ointment has been studied.
The Estimate of Heterosis Effects of Sheep Body Weights in Different Ages Abdullah Hameed Salim
Journal of Global Pharma Technology Volume 10 Issue 10: 2018
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Abstract

The current study was carried out at the Radwaniyah station / Ministry of Agriculture, which included analysis of data of local awassi sheep, Assaf and crossing Assaf (local Awassi ×Assaf). Records included weights at birth and weaning and in ages of 6, 9 and 12 months for the three genetic groups above. We aimed to study the effect of the genetic group on the lamb’s weights at different ages and the effects of the hybrid vigor resulting from the crossing of local awassi sheep with Assaf sheep to the traits of the weights in ages from birth to one year old. The results showed that the genetic group had a significant effect (p˂0.01) in all the studied traits while the effect of hybrid vigor was not significant for all studied traits, but it was similar to some previous studies, with 10.36, 12.20, 5.80, 6.49 and 4.92 % for weights at birth, weaning, 6 months, 9 month and 12 month respectively.
The Association Between Brachial Ankle Pulse Wave Velocity and Left Ventric Mass Index In Patients With Hypertension Budi Susetyo Pikir
Journal of Global Pharma Technology Volume 11 Issue 04.
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Abstract

Background: Arterial stiffness has been considered as a modest method in detecting the arterial burden that can trigger left ventricular hypertrophy in the heart. Increased left ventricle hypertrophy in hypertension patients is a predictor which has impact in the increase of morbidity and mortality. Objectives: We aimed to investigate the association between brachial ankle pulse wave velocity (BaPWV) and left ventricle mass index (LVMI) in patients with hypertension. Material and Methods: This study was conducted by collecting secondary data of 40 hypertension patients aged >40 years old, suffered from hypertension >1 year and have encountered brachial ankle pulse wave velocity test and echocardiography test. Results: There was a significant positive correlation between brachial ankle pulse wave velocity and left ventricle mass index in hypertension patients with r = 0.493 dan p = 0.001. Also, there was a significant correlation between BaPWV and Relative Wall Thickness with r = 0.404 and p = 0.01. There was a significant difference of LVMI value in males and females with the result of (117.78+22.70 and 100.15+16.82, p = 0.008). In contrast, there was no significant difference in BaPWV value in males and females (1865.63+322.29 and 1811.08+350.28). It was also obtained a significant correlation between age factor and systolic blood pressure with LVMI and BaPWV (r = 0.493, p = 0.001). Conclusions: There was significant positive correlation between BaPWV and LVMI in hypertension patients. The arterial stiffness was an indicator of increased left ventricle mass index in hypertension patients.Keywords: Brachial ankle pulse wave velocity, Left ventricle mass index, Hypertension, Heart.
Microencapsulation in Food Science and Biotechnology in Iraq Marwah Ali Oudah
Journal of Global Pharma Technology Volume 12 Issue 02 (2020) Feb. 2020
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Abstract

microcapsules can release their contents at controlled speeds under specific conditions, and can protect the encapsulated product from light and oxygen. The microencapsulation consists of microparticles formed by a porous polymeric membrane containing an active substance. The material or mixtures of materials to be encapsulated can be covered or trapped within another material or system. A microcapsule consists of a semi-permeable, spherical, thin and strong membrane around a solid / liquid center. The materials used for encapsulation can be gelatin, fats, oils, gum arabic, calcium alginate, waxes, wheat starch, corn, rice, potatoes, nylon, cyclodextrin, maltodextrin, sodium caseinate, whey protein or protein of soy. The applications of microencapsulation are directed to the industry, it is given to the textile, metallurgical, chemical, food, cosmetics, pharmaceutical and medical industries. Among the techniques used to microencapsulate are spray drying, cooling drying, freeze drying, coacervation and extrusion. The substances that are microencapsulated can be vitamins, minerals, dyes, prebiotics, probiotics, nutraceutical flavors, antioxidants, odors, oils, enzymes, bacteria, perfumes, drugs and even fertilizers.Keywords: Encapsulation techniques in food, Encapsulation theory.
Study Some of the Risk Factors on Total Antioxidant Capacity in Iraqi Patients with Sporadic Colorectal Cancer Moaed E. Al-Gazally
Journal of Global Pharma Technology .
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Abstract

Colorectal cancer is one of the most frequent malignant diseases in the developed countries. It was reported that total antioxidant status is being play a very important roles in development of carcinogenesis. The aim of  this study to assess of some risk factors such as age, gender, obesity, and smoking status on total antioxidant status in patients with sporadic colorectal cancer in Iraq. This investigate was completed by using colorimetric method to measure of total antioxidant capacity (T-AOC) and assess the risk factors depending on the levels of T-AOC. All patients included in the present study were getting adjuvant chemotherapy regimen  and subdivided into two groups according to Duke´s classification of malignant into early stages A+B and advance stages C+D, cancer site (colon or  rectum), and according to the number of dose of chemotherapy regimen (half dose or total dose). The present study showed negatively correlation (r = -0.567) (p<0.05) between T-AOC and ages of patients with sporadic CRC (p< 0.001). The levels of T-AOC decreased in both ever and never smoking compared to control group (p< 0.05). The results showed highly significant difference (p< 0.001) of T-AOC levels between A+B and C+D groups depending on age. The levels of T-AOC was decreased markedly in patients with ages less than 50 years compared to ages more or equal 50 years in both combination stages A+B and C+D (the higher difference was observed in same age and different state). In conclusion the risk factors that studied in this work may be have the main role to decrease levels of T-AOC and in result will increase the probability of injury with colon and rectal cancer in Iraqi population.Keywords: Total antioxidant capacity, Smoking status, Sporadic Colorectal cancer, Adjuvant chemotherapy, Obesity status
OSSEOINTEGRATION OF THE INTRAMEDULLARY IMPLANT IN FRACTURE OF THE DIAPHYSIS OF A LONG BONE A.V. Popkov
Journal of Global Pharma Technology Volume 08 Issue 11
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Abstract

In the experiment on dogs, nails coated with hydroxyapatite were introduced intramedullary in the tibia. By using light microscopy of histological sections and scanning electron microscopy, bone marrow space around the implant was studied. It was found that an area of active apposition bone formation is formed around the nails, and bone case is formed with the properties of osteogenesis conductor and inductor, providing directional growth of bone tissue and reparative bone formation. The extent of osseointegration of intraosseous implant was determined by separation method when removing intramedullary nail a month after the surgery. Active implant osseointegration provides guaranteed diaphysis fracture healing in 2-3 weeks. Keywords:  Intramedullary osteosynthesis, Hydroxyapatite coating, Reparative bone formation, Osseointegration.
Expression of α TNF in Some Organs of Rabbits Treated with Aflatoxin B1 Fadia Falah Hassan
Journal of Global Pharma Technology .
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Abstract

Our study was designed to detect the effect of aflatoxin B1 in liver, kidney and spleen of New Zealand White rabbits and investigate the role of α TNF in aflatoxin B1-induced the same organs toxicity. Histopathological study showed various pathological effects of rabbit’s organs treated with 0.3 mg/kg body weight intraperitoneally with aflatoxin B1 in comparing with control animals. Alpha TNF was used as a marker for immunohistochemically study, results clarified that it was no expression in control animals (score =0) while results of animals treated with 0.3 mg/kg body weight intraperitoneally showed that liver was the most susceptible organs whereas the expression was severe (score =4), strong (score =3) and moderate (score =2) in liver, kidney and spleen respectively.Keywords: Aflatoxin B1, Histopathology, Immunohistochemistry, α TNF.
He-Ne Monochromatic Light with Selenium nanoparticles as Medical Technique Hassan Tuhmaz
Journal of Global Pharma Technology Volume 11 Issue 07
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Abstract

In this study, the photo-thermal dealing of cancer with Se nanoparticles is studied. This processes for tissue under the influence of heat by a laser source with dose injection the selenium nanoparticles on the affected area. The bio-heat equation is solved by numerical simulation methods. Results are summarized in the effect on the increase of temperature at different time stages. These results appeared that the depth diffusion increasing heat raising during the increasing the time duration of exposure. Thus, it concludes the peak value of depth with controlled temperature.Keywords: Selenium nanoparticles; Heat raising; Medical technique.
Study of the Border Adjustment of Indirect and Direct Restorations by Thermo cycling Method with Following Staying Yulianna Enina
Journal of Global Pharma Technology Volume 12 Issue 09 (2020) Sept. 2020
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Abstract

According to modern concepts, the marginal permeability of restorations, the presence or absence of micro leaks, are the main factors determining the service life of the restoration. The restoration of teeth is subjected to several different types of stress - one of which is temperature fluctuations in the oral cavity. It is known that when eating food, brushing teeth, etc. the temperature in the oral cavity changes and affects the physical and mechanical properties of the hard tissues of the teeth, as well as of the restorative material, and in some cases leads to deformation of the zone of connection of the restorative material with the tooth surface up to its destruction. The thermal cycling procedure makes it possible to simulate the influence of this factor on the conditions of functioning of the reducing material; this is achieved by exposing the sample to a limited number of thermal cycles, which means of an artificial "aging" of the sample in laboratory conditions. Keywords: Direct restoration, Indirect restoration, Inlay, Thermal cycling, Micro leakage, Marginal fit.
Analysis of the Employment Profile Offered by Employers to Graduated Bachelors of “Public Health” In Medical Universities Raushan Z Magsumova
Journal of Global Pharma Technology Volume 10 Issue 05: (2018) May2018
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Abstract

The purpose of this article was to improve the educational program for Bachelors of "Public Health" to prevent problems with their further employment. We have carried out an anonymous survey; we have also studied the curricula and employment lists of graduates. The research on the first three widespread vacancies for Public Health graduates in three medical universities has revealed the following positions: Epidemiologist, Statistics Specialist and Quality Assurance Manager. This should be taken into account in appropriate educational programs.Keywords: Employment analysis, Employment, Public Health graduates, Employment profile.

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