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Journal of Global Pharma Technology
Published by Universitas Udayana
ISSN : 09758542     EISSN : -     DOI : -
Core Subject : Health,
Medicine & Pharmacology
ournal of Global Pharma Technology is a monthly, open access, Peer review journal of Pharmacy published by JGPT Journal publishes peer-reviewed original research papers, case reports and systematic reviews. The journal allows free access to its contents, which is likely to attract more readers and citations to articles published in JGPT. JGPT publishes original research work that contributes significantly to the scientific knowledge in pharmacy and pharmaceutical sciences- Pharmaceutics, Novel Drug Delivery, Pharmaceutical Technology, Cosmeticology, Biopharmaceutics and Pharmacokinetics, Pharmacognosy, Natural Product Research, Medicinal Chemistry, Computational Chemistry and Molecular Drug Design, Pharmaceutical Analysis, Pharmacology, Pharmacy Practice, Clinical and Hospital Pharmacy, Cell Biology, Genomics and Proteomics, Pharmacogenomics, Bioinformatics, Biotechnology and Applied Computer Technology. For this purpose we would like to ask you to contribute your excellent papers in pharmaceutical sciences.
Arjuna Subject : Kedokteran - Onkologi
Articles 2,439 Documents
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Role of Oxytocin and Cortisol Simultaneous with the Cellular Oxidative Stress in Preventing Pregnancy in Females with Un Known Infertile Cause Who Undergone to Artificial Fertilization Rasha Hasan Jasim
Journal of Global Pharma Technology Volume 10 Issue 06: (2018) June 2018
Publisher : Journal of Global Pharma Technology

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Abstract

Eighty two women were enrolled in the present study, they are classified into two groups, and the first included 42 females aged 23 – 42 years who had never a normal pregnancy. They had to undergo IVF with a regular 6 month menstrual cycle before applying for an IVF at the Infertility Treatment Center in Sadder City Medical in Najaf, Iraq. The second group included 40 females with age rang 22 – 40, were selected as control, results of the present work were summarized in the below table. Oxytocin and cortisol levels were evaluated in the present work in addition to several oxidants and antioxidant parameters. Results of the study showed significant elevation in the BMI (Mean ± S.D.) at females suffered unknown infertile cause comparison to healthy females and this elevation was directly correlated to pregnancy prevention. Outcomes recorded statistically significant decrease in the oxytocin and SOD Activity (U/dl) in the sera of females who submitted for artificial insemination, while all of cortisol, MDA, NO, and Cp concentration seemed to be higher in the sera of patient’s women than their corresponding in the control group. Results of the study illustrated highly significant correlation between oxytocin and cortisol (r = - 0.735 at p = 0.001), as well as oxytocin and NO (r = - 0.779 at p = 0.001, and between MDA and NO (r = 0.882 at p = 0.001). More than; the study showed there are significant correlation (r = 0.832) between Cortisol with NO, and MDA with SOD Activity (r = -859) at p = 0.005. The study concludes that oxytocin could directly affect in the preventing of normal pregnancy moreover in decrease of the success of the artificial insemination process.    Key words: Oxytocin, Cortisol, Artificial Insemination, Female Infertility, Oxidative Stress, SOD activity, NO, MDA.
EFFECT OF SOME CHEMICAL ELICITORS ON SOME SECONDARY METABOLITE INDUCTION OF CORDIA MYXA L. IN VITRO alaa jabbar taha
Journal of Global Pharma Technology .
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Abstract

Cordia myxa a tree belongs to boraginaceae family contained many secondary products like Flavonoids and Alkaloids. So uses as anti - inflammation, and antibacterial .The objective of this research to increase some secondary products from callus extraction by using chemical elicitors, like ZnSo4 and CoCl2 in various concentration, the method of Budhiraja was use to estimate the concentration of secondary products. Results showed that 0.5mg/l from ZnSo4 lead to significant increase compound dihydroxyrobmetin, Rubinin, and Chlorogenic reaching 2.95, 218.44, 60.99, µg/ml respectively. Moreover, had 2.5mg/l of ZnSo4 concentration negative impact on concentration of secondary metabolites, all compound decreased except datiscoside that arrived to highest rates significantly 70.63 µg/ml. While treatment 0.5 mg/l CoCl2 lead to decrease all compounds except hesperdin, which was significantly increase to 71.42 µg/ml, the concluded of this research showed that 0.5mg/l of CoCl2 and 2.5mg/l of Zno4 had negative effect on most  concentration of secondary metabolites. 
Knowledge of Health Care Workers Regarding Zika Virus Infection in Baghdad City / Iraq Atta Ah Mousa Al -Sarray
Journal of Global Pharma Technology Volume 11 Issue 09: (2019) September 2019
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Abstract

Background: WHO declared that   Zika virus infection as a global public health emergency of international concern. Objectives: To determine the level of knowledge of Health care workers regarding Zika virus in Baghdad city. Subjects and Methods: A descriptive; cross sectional study conducted at 41 randomly selected (multistage sample) hospitals and primary health care centers  in Baghdad city, included 600 health care workers, The data collection continued for the period starting on 11th November-2018 ending on 3th March 3, 2019. Results: The results of demographic data was conducted on health care workers with their mean age (37.8±10.7)  years ranging from (20-66) years and the highest percentage (34.2%) were in the age group (30-39) years and the lowest percentage(3.3) were in the age group (age>60) years, most of studied sample were females (73%) and married (71%),regarding Educational qualification the highest percentage (57%) from College and higher educational level, the lowest percentage from secondary school, the majority of studied sample (60%)  were medical staff and not well informed regarding the association of Zika virus and Guillain-Barre syndrome, the diagnostic test, and management options, There knowledge was mainly gained from Internet, Radio and T.V. Conclusion: This study concluded that the health care workers had fair and acceptable knowledge regarding Zika virus in Baghdad city during the period of study . Recommendation: Co-ordinate educational programs are needed to increase the knowledge level of health care workers about Zika virus and other emerging diseases, these programs can be extended to include the medical students, travelers and pregnant women. Key words:  Zika virus, Knowledge, Health care workers, Baghdad city.
The Effect of Focus and Attention and Its Correlation with the Accuracy of Spike Performance with the Rotation and Deception in Volleyball Majid Hameed Merzah
Journal of Global Pharma Technology Volume 10 Issue 05: (2018) May2018
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Abstract

The current study aimed to identify the relationship of statistical research to the effect of concentration and attention and their relation to the accuracy of the performance of the spike and rotation of the volleyball of the sample of the research, which was subjected to the test of the impact of concentration and attention to volleyball and the skill test dealt with the study. The researchers used the experimental method to suit the nature of the research, where the study was conducted on a sample of students of the second stage in the Faculty of Physical Education / Karbala University for the academic year 2017 (2018) and represent the age group (20 - 22) years, the number of (60) students, (80%) of the original research community were selected by random method. The researcher used the following statistical means (Percentage, mean, standard deviation, and correlation coefficient - Pearson). The researchers concluded that the concentration and attention test showed a significant correlation in the spike test and the volleyball deception.Keywords: Focus and attention, He spike of rotation, The spike of deceit and volleyball.
Effect of Infection with Toxoplasma and Cytomegalovirus on (IgG and IgM) Levels in Women with Primary Infertility from Wasit Province-Iraq Hind A. Hanoon
Journal of Global Pharma Technology Volume 11 Issue 2: 2019
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Abstract

The purpose of this study is to clarify the respective roles of the parasite Toxoplasma and cytomegalovirus in primary infertility women in Wasit governorate, the samples were collected from each of infertility center at Al-Kut Hospital and Al-Zahra Teaching Hospital during the period from of 20may to 20 Oct. /2016. and was compared with the control groups Pregnant  and healthy women , it was the reconstruction of aggregates rate between 17- 45 years, and have been working with ELISA .this study showed  a significant decrease (P <0.05)  in IgM in  first and second  groups when compared with healthy women and no significant when compared with pregnant women at toxoplasmosis .In Cytomegalovirus, significant increase (P <0.05) for all categories compared with healthy in IgM  and significant increase (P <0.05) in first and third categories in IgG when compared with pregnant women and significant decrease (P <0.05) in second group in IgM when compared with pregnant women.Keywords: Toxoplasma gondii, Cytomegalovirus, Infertility women, Pregnant women, ELISA.
The Relationship between Nutritional Status and Lifestyle with Risk of Early Menarche among Adolescent Iqlima Dwi Kurnia
Journal of Global Pharma Technology Volume 12 Issue 01
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Abstract

Introduction: Early menarche is one of the major of concern in reproductive health, and affects a large number of women throughout their reproductive life from early adolescent. Early menarche is an important indicator of sexual and reproductive health. The aim of this research was to explain the relation between nutritional status and lifestyle with early menarche case in-adolescent in Surabaya. Method: The research design used was cross sectional. The study population consisted of 232 early-adolescent. The study sample totaled 145 early adolescents based on Purposive sampling with a study period of 2 months. The independent variables were nutritional status and lifestyle, while the dependent variable was early menarch. The data collection method used was a questionnaire sheet filled out by the adolescents and BMI measurement. The statistical analysis used Spearman rho (α ≤ 0, 05). Results: The results showed that nutritional status and lifestyle were positively related to early menarche in early-adolescents (p = 0.000). Discussion: Overweight nutritional status or high BMI and unhealthy lifestyle will tend to experience early menarche. Early menarche can lead to a premature menapouse as well, the risk of heart and bone disorders.Keywords: Nutritional status, Lifestyle, Early menarche, Early-adolescent.
Used of Growth Charts among Children Age 1-5 Years Old and its Effects on Child Health in Al-Hillah City Amean A. Yasir
Journal of Global Pharma Technology Volume 9 Issue 10
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Abstract

Depending on the height, weight and head circumstances derived from 400 children (200 boys and 200 girls) ranged from one to five years of age. The data collected randomly from different health care centre of Hillah. The result showed that boys were significantly heavier and taller than girls in the first years of life. Height measurement revealed that boys head are bigger than the girls.  Objective this study aimed to suggested new technique of physical growth curve chart for children under five years old of age in non-probability sample.Keywords: Physical Growth charts, Child health, WHO, CDC, Weight, Height and head circumference.
Synthesis and Characterization of Some Capsaicin Derivatives and Study their Pharmacological Hydrolysis Faris Hamood Mohammed
Journal of Global Pharma Technology .
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Abstract

One of the alkaloid compounds that were found in the fruit of the Capsicum genus is a Capsaicin, which provides its spicy flavor. Capsaicin extracted directly from fruit and limited use in clinical trials to support the biological activity. In this research, using cationic polymerization were  carried out to the synthesis of drug-spacer polymer to obtain more able as hydrolysis proceeded and more convenient for hydrolysis of attachment of the appropriate pendant drugs, through increases the distance between drugs as a bioactive and backbone of the polymer chains. All prepared drug polymers were characterized by FTIR, UV-visible, TGA and 1HNMR techniques.
Study the Effect of Some Growth Factors on the Production of L-Asparaginase Enzyme by Fungal Isolate Aspergillus flavus Walla H. Shuker
Journal of Global Pharma Technology Volume 11 Issue 05.
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Abstract

Nine filamentous fungi from infection fruits and vegetables .Seven isolated were of high productivity for L-Asparaginase enzyme compared with other isolates, this isolates were Aspergillus flavus, A.niger, Pencillium sp., Fusarium sp., Aspergillus flavus was the best isolate for Asparaginase production, depending on diameteron pink colour on the medium plates. Studied the effect of nitrogen and carbon sources, and PH the resulted revealed that the maximum Asparginase production was the following condition: PH 6.0, Glocose as a carbon source, Ammonium sulphate was (121.28) U/100ml.
Effect of Topical Serratiopeptidase on Facial Wound Healing in Rabbit Faehaa A. Al-Mashhadanee
Journal of Global Pharma Technology Volume 12 Issue 06 (2020) June 2020
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Abstract

Abstract Objective: Serratiopeptidase (SRP), an enzyme with great effect in opposing inflammation. Applications of enzyme topically provide advantage of direct entery to the location of action. This study examined the possibility of using topical SRP preparations in the formula of ointments and to assess the topical effect of SRP in facial wound management in rabbits. Material and Method: healthy male rabbits weight,1.25 ± 0.25kg divided into four groups: group one animals received no treatment, group two animals treated with Vaseline only, group three and four were treated by SRP (0.5% and 1%) respectively. Standard incisions were done on submandibular region of all rabbits. Wound healing assessment was determined by histological method. Results: group one and two showed incomplete closure of the wound with poor re-epithelization, while other groups (three and four) demonstrated complete closure of the wound with good re-epithelization. Conclusion: topical application of SRP has ability to improve facial wound healing in rabbits. Keywords: Serratiopeptidase, Facial wound, Rabbit.

Page 31 of 244 | Total Record : 2439

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