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Journal of Global Pharma Technology
Published by Universitas Udayana
ISSN : 09758542     EISSN : -     DOI : -
Core Subject : Health,
Medicine & Pharmacology
ournal of Global Pharma Technology is a monthly, open access, Peer review journal of Pharmacy published by JGPT Journal publishes peer-reviewed original research papers, case reports and systematic reviews. The journal allows free access to its contents, which is likely to attract more readers and citations to articles published in JGPT. JGPT publishes original research work that contributes significantly to the scientific knowledge in pharmacy and pharmaceutical sciences- Pharmaceutics, Novel Drug Delivery, Pharmaceutical Technology, Cosmeticology, Biopharmaceutics and Pharmacokinetics, Pharmacognosy, Natural Product Research, Medicinal Chemistry, Computational Chemistry and Molecular Drug Design, Pharmaceutical Analysis, Pharmacology, Pharmacy Practice, Clinical and Hospital Pharmacy, Cell Biology, Genomics and Proteomics, Pharmacogenomics, Bioinformatics, Biotechnology and Applied Computer Technology. For this purpose we would like to ask you to contribute your excellent papers in pharmaceutical sciences.
Arjuna Subject : Kedokteran - Onkologi
Articles 2,439 Documents
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Molecular Identification of Extended-spectrum β-lactamase Resistant Genes in E coli Recovered from Individuals Suffered Urinary Tract-based Infection Sara K. Al-Zubaidi
Journal of Global Pharma Technology Volume 11 Issue 2: 2019
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Abstract

The intended purpose of the current identifying study was to know the recent occurrence of E. coli-related extended-spectrum resistant-genes of blaCTX-M, blaSHV, blaTEM and blaAMPC that are responsible for community-based acquired urinary tract infection (CAUTI) and nosocomial infections (NCI). The study also was intended to reveal the genetic-based links between recovered strains. To answer these questions, non-similar 50 isolates of E. coli were recovered from UTI samples handed by 3 hospitals in Babylon City, Iraq. These samples were subjected to cultivation processes and a polymerase chain reaction technique (PCR). The resistant genes, according to PCR, were detected in 10 positive-ESBL phenotypes of the isolates. Using PCR, The blaCTX-M and blaAMPC genes were 100%-frequently identified in those 10-positive samples. However, the other genes were detected in low rates in those samples. The results, here, identify the important role of the horizontal gene transfer (HGT) in obtaining resistance by the E. coli isolates against β-lactamase-related antibiotics in Iraq.      Keywords: E. coli, Extended, β-lactamase resistant genes, Spectrum.
Bioethanol Production from Starch- A Short Review G. Veeramani
Journal of Global Pharma Technology Volume 11 Issue 12 (2019) December 2019
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Abstract

Bioethanol is an alcohol made by fermentation, mostly from carbohydrates produced in sugar or starch crops such as corn or sugarcane. Cellulosic biomass, derived from non-food sources, such as trees and grasses, is also being developed as a feedstock for ethanol production. Concentrated acid hydrolysis, dilute acid hydrolysis, wet milling process, dry milling process, sugar fermentation and fractional distillation process were used for production of bioethanol. Bioethanol is colourless and clear liquid. Brazil and United States of America are the largest ethanol producers, widely used alternative automotive fuel consists lower toxicity level. India produced 111 crore liters of ethanol in year 2015-2016, while the production was 38 crore liters in 2013-2014. Bioethanol fuel is mainly produced by the sugar or cellulosic fermentation process and it is transport fuel to replace gasoline and power generation by thermal combustion, fuel for fuel cells by thermochemical reaction, fuel in cogeneration systems and feedstock in the chemical industries because it is much more environmental friendly.Keywords: Bioethanol, Starch, Fuel, Hydrolysis, Hexoses, Fermentation.
Retrospective Analysis of Quality of Pharmacotherapy for Children with Acute Respiratory Infections on Background of ABC /VEN/ Frequency Analysis Based on Data of Patientsꞌ Medical Histories Vera Ulanova
Journal of Global Pharma Technology Volume 10 Issue 07: (2018) July 2018
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Abstract

Increase in frequency of acute respiratory viral infection (ARVI) and difficult economic situation in Ukraine require rational use of financial resources to treat this disease in children. Comprehensive analysis on background of additional pharmacoeconomic methods: ABC-, VEN- and frequency analysis based on study of results of 180 children with ARVI - allows to estimate  cost of drugs in hospital of Burin town, Sumy region, Ukraine. It has been found out that part of money turned out to have been used inefficiently for treatment of children with ARVI and pharmacotherapy not always to be in line with government regulations because 16.15 % - 38.69 % of all funds were spent on drugs not included in Clinical Protocols for ARVI and related diseases. That is why there is an opportunity to cut down expenditures spent on unnecessary drugs during treatment period.Keywords: Drugs for treatment of children with acute respiratory viral infections, Clinical and economic analysis.
Effects of Topiramate Drug on Biological, Hormonal and Histological Parameters in Pregnant Albino Rats and Embryos Amel A. Altaee
Journal of Global Pharma Technology Volume 9 Issue 10
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Abstract

The present study aimed to elucidate the effect of Topiramate drug (100 mg/kg b.wt) on some parameter in pregnant albino rats including serum reproductive hormones level , Luteinizing Hormone (LH), Follicle Stimulating Hormone (FSH) and Estradiol (E2)), body weight gain, uterus weight, on the implantation and  desorption of embryo, diameter of follicle in ovary and development of neural tube of embryos in pregnant albino rats for different periods (7,9,12,14 and 21 days) of gestation . The hormonal results showed no significant change (P ≤ 0.05) in the mean levels of LH and FSH hormone for treated groups when compared with control groups for days 7, 9, 12, 14 and 21 of pregnancy, but there was a significant increase (P ≤ 0.05) in the mean levels of E2 hormone for treated groups as compared with control groups. There is significant increase in the numbers of desorption embryos in treated groups for days 7, 9, 12, 14 and 21of pregnancy, as compared with control groups. While the study showed significant decrease in the number of implantation sites in treated groups as compared with control groups. The results of this study revealed no significant increase in the secondary follicle diameters in treated groups of 9 and 12 days and tertiary follicle of 7 days of pregnancy, as compared with control. The diameters of epithelial and marginal layers of neuro-ectoderm in days 9 of pregnancy for treated groups showed significant increase as compared with control groups.Keywords: Topiramate, Rats, Embryo, Neural tube, Ovary.
The Most Important Bio-movement Abilities and its Correlation to the Performance of the Skill of Forehand Jump on the Surface of Movements for the Women's Gymnastic Ruaa Ali Hussein
Journal of Global Pharma Technology Volume 10 Issue 10: 2018
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Abstract

The researchers, according to the nature of the educational process of the basic skills in the gymnastic noted the weakness of the capabilities in the performance of the performance of the players of the Faculty of Education for Girls University of Kufa, especially in the performance of the skill of the leap of the front hands on the ground movements of women, Therefore, the researchers sought to study the relationship between the most important bio movement abilities and the performance of the skill of the frontal leap on the surface of the movements of the ground in the women's gymnastics. The descriptive approach was chosen in the method of correlative relations to suit the nature of the research problem. The research community was (10) Kufa. The first experiment was conducted first and then the main experiment of the research procedures was conducted. The results that were dealt with were obtained using the statistical file (SPSS) which enabled the researchers to reach the conclusion that there is a positive correlation between the more bioethics (flexibility, compatibility, explosive arm force, and balance), the better the performance is for the better. The recommendations are the need to pay attention to the training of the bio movement abilities of the various sporting events.Keywords: Bio-movement, Performance, Surface of movement’s and gymnastic
Use of Integrative Medicine Approaches for Treating Adults with Sleep Disturbances Raad Issa Taqi Al-Shammaa
Journal of Global Pharma Technology Volume 11 Issue 04.
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Abstract

Objective: This learning recognized the occurrence then effectiveness of perceived, influencing elements or assessment about data sources as much well as like boundaries then facilitators for the usage regarding IMA between the past 12 months in accordance with treat adults together with sleep disorders. Background: There are no researches evaluating the use concerning complementary remedy strategies among adults together with couch disorders. Method: Perform a sectional scan. Adults along intentional lie issues had been elected beside a lie center in a sanatorium into Taiwan. Binary logistic regression used to be back after analyze yet examine variations into use corporations then non-use of. Results: The response rate was 94.5% (n = 515). The occurrence over the uses of complementary medication techniques was 53.4% (n = 275). The almost frequent IMA is music. However, the near fine integrative medicine techniques were acupressure, accompanied via tune and meditation. Independent explanatory variables had been academic attainment, quantity regarding persistent diseases / symptoms, or wholesome lifestyles because IMA use. The near common source concerning statistics is television / radio. Was the top facilitator and obstruction in imitation of the uses on complementary medicinal drug techniques beyond the facet results of slumbering drugs yet confined access? Conclusions: IMA is ancient through a big share over adults in conformity with deal with lie problems between Taiwan. The results concerning that lesson recognized important explanatory variables because of IMA utilizes and furnished a primary perception regarding the elements over IMA utilizes into adults along couch problems so much are of precise value to health ponderabil vendors among the work related with their patients.
The Study of Structural- Mechanical and Physicochemical Properties of the Drug Antimicrobial and Anesthetic Action Viktoria Tarasenko
Journal of Global Pharma Technology Volume 12 Issue 06 (2020) June 2020
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Abstract

Introduction: This work is devoted to study of structural-mechanical and physicochemical properties of soft drugs with antimicrobial and anesthetic action. The purpose of this study was to study the effectiveness of physicochemical properties of soft drugs. Materials and methods: In the process of performing the work, pharmaco-technological, physicochemical, structural-mechanical, biopharmaceutical and biological research methods according to the State Pharmacopoeia of Ukraine were used. Results and discussion: The sample was considered stable if no stratification was observed in the tubes after centrifugation. If at least one of the tubes was observed stratification of the sample or the selection of sediment, the analysis was repeated with new portions. The type of emulsions was determined by dilution and staining methods. The study of local anesthetic activity was performed on a model of rabbit eye anesthesia. The experiment was performed on 25 male rabbits, which were divided into 5 groups of 5 rabbits each. Conclusions: The study of structural-mechanical and physico-chemical properties of drugs in the form of a cream is the basis for improving its therapeutic efficacy, mechanical stability and consumer properties. Keywords: Soft drugs, Antimicrobial action, Anesthetic action, Colloidal stability, Thermal stability, Emulsions, Rheogram.
Electrical Stimulation Type (Body Relax) in the Treatment of Chronic Lower Back Pain for the Players Physical Strength Isam Talib Abbas
Journal of Global Pharma Technology .
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Abstract

Chronic back pain is one of the most common injuries in physical strength players. The importance of research is to relieve pain in the lower back muscles and reduce the complications that result from chronic pain reduction using a type of electrical stimulation with frequencies dedicated to muscle relaxation. The problem of research lies in the lack of use of technical means of effective and direct impact in the rehabilitation of lower back injuries of physical strength players, especially that this group of players need special care in the process of rehabilitation. The aim of the research was to use the electromyostimulate (EMS) type body relax in the treatment of chronic low back pain and to know its effect on those with the pain. The researchers used the electrical stimulation used by the researchers to have a positive effect in reducing chronic pain and rehabilitation of the lower back muscles of the physical strength players in question. The research method used the experimental method of one group and identified the research community of players with low back pain in the physical strength of the successors in Najaf, and the sample of the study (6) injured players were chosen by deliberate method, and used the form of measuring the degree of pain according to the test Shopper and physical tests The training program included the use of EMS for muscle relaxation. The researchers used the statistical program (SPSS) and used the following statistical means (median, spring deviation, and toxin).The most important conclusions reached by the researchers are:1. The electrical stimulation of the body relax is a major role in reducing the level of chronic low back pain and improve the physical flexibility of the muscles of the lower back of the players of physical strength.Keywords: Electrical stimulation, Chronic, Lower back pain and Physical strength.
Effect of Using the Financial Information Technology System (SANAMA: Real-time Monitoring System of the Department of Financial Monitoring and National Treasury) on the Transparency, Accountability, and Audit of the National Budget Statement Ahmad Barani
Journal of Global Pharma Technology Volume 08 Issue 04
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Abstract

The aim of this study was to investigate the effect of financial information technology system (SANAMA: real-time monitoring system of the Department of Financial Monitoring and National Treasury) on the transparency, accountability, and audit of the national budget performance statement. This system improves management of the financial system in the area of resource consumption and national budget through a continuous financial control and supervision of the public resources consumption. The lack of timely and quick access to information and audit data resulting from traditional implementation of affairs reduces the accuracy and quality of the audits in addition to increasing the cost and time. Accordingly, the Ministry of Economic Affairs and Finance launched an electronic surveillance system known as the "SANAMA" as one of the major IT-based developments in the country in order to resolve the problem mentioned above and also to change and update the audits. Data were collected using questionnaire method. Based on one-sample t-test, the respondents represented a consensus of opinion on three issues raised in this research including improvements in auditing, transparency, and accountability of financial statements in executive organizations as the consequences of SNAMA system usage.Keywords: Information technology (IT), SANAMA system, Transparency, Accountability, Audit.
Vitamin D3 Level and Its Receptor of Patients with Psoriasis: A Case Control Study Abdulsamie Hassan Altaee
Journal of Global Pharma Technology .
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Abstract

Psoriasis is multi-factorial disease resulted in response to increase secretion of inflammatory cytokines or deficiency in certain vitamins such as vitamin D3. This study aims to evaluate the levels of vitamin D3 and its receptor (VDR) in psoriatic patients and healthy control, additionally to determine the ratio between vitamin/receptor and their relative risk in the pathogenesis of psoriasis. This study was design as a case-control study and includes 45 psoriatic subjects and 45 healthy controls. The results of currents study were found a significant decrease in vitamin D3, VDR levels and vitamin D3/ VDR ratio when compared with the healthy control group. The relative risk for VDR levels with psoriasis found to be positively significantly associated, whereas those for vitamin D3 levels with psoriasis were insignificant. In conclusion, the relative risk for VDR is more than that for calicitriol and this support the pathogenic role of VDR abnormality in psoriasis.Key words: Vitamin D, Vitamin D receptor, Psoriasis, Keratinocyte, Babylon.

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