Jurnal MedScientiae
Jurnal MedScientiae adalah jurnal yang dikelola oleh Fakultas Kedokteran dan Ilmu Kesehatan Universitas Kristen Krida Wacana. Jurnal ini mempublikasikan artikel-artikel secara open access dalam lingkup bidang kedokteran dan kesehatan seperti kedokteran dasar, bioetika kedokteran, biologi sel, biologi molekuler, genetika, fisiologi, biokimia, bioinformatika, anatomi, farmakologi, kesehatan masyarakat, dan ilmu biomedik lainnya.
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47 Documents
<![CDATA[Efektivitas Tanaman Sambiloto (Andrographis Paniculata) dan Senyawa Andrographolide dalam Menghambat Infeksi COVID-19 : Literature Review ]]>
<![CDATA[Shintia Christina]]>;
<![CDATA[Kristin Natalia Meta Kali]]>;
<![CDATA[Reni Angeline]]>
<![CDATA[ Jurnal MedScientiae Volume 1 No 01 : Mei - Agustus 2022 ]]>
Publisher : <![CDATA[Fakultas Kedokteran dan Ilmu Kesehatan Ukrida ]]>
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DOI: 10.36452/jmedscientiae.vi.2496
<![CDATA[Sambiloto (Andrographis paniculata) has long been used as a herbal medicine by local Indonesian people, especially because it is easy to find in the yard of the house. Since the onset of the COVID-19 pandemic, various handling efforts have been carried out, ranging from pharmacological and non-pharmacological. Various herbal plants that have the potential to be used as COVID-19 treatments have begun to be tested, including A. paniculata. To find out the benefits and mechanisms of A. paniculata in the treatment of COVID-19, a literature review study was conducted by tracing data in the form of scientific journals published in the last 2 years since the pandemic began. At the end of the results of this study, A. paniculata demonstrated its function in inhibiting COVID-19 through the mechanism of preventing virus attachment to surface receptors and inhibiting viral replication.]]>
<![CDATA[Faktor Risiko yang Behubungan dengan Swamedikasi Demam pada Anak di Desa Lubuk Empelas Kecamatan Muara Enim, Privinsi Sumatera Selatan ]]>
<![CDATA[Fedora Jolie Jolie]]>;
<![CDATA[Djap Hadi Susanto]]>
<![CDATA[ Jurnal MedScientiae Volume 1 No 01 : Mei - Agustus 2022 ]]>
Publisher : <![CDATA[Fakultas Kedokteran dan Ilmu Kesehatan Ukrida ]]>
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DOI: 10.36452/jmedscientiae.vi.2505
<![CDATA[Self-medication is a community action in overcoming symptoms of the disease by using over-the-counter drugs without going to a doctor. Self-medication by the community is generally obtained from generation to generation from previous experience. Symptoms of illness that are treated, generally are fever. The study aims to determine the factors associated with self-medication for fever in children. The research method used is a cross-sectional approach, data were collected using a questionnaire obtained by interviewing and filling out a questionnaire. Subjects are children aged 1-12 years, questionnaire to the child’s mother. Data were analyzed using univariate and bivariate. Results: The proportion of fever self-medication behavior was 69%. The average education level of high school graduates, and family income is below the regional minimum wage. The majority of children were in the range of 5-9 years. Self-medicated by their mothers with fever due to common illnesses such as colds. There was a relationship between the mother's level of knowledge (p = 0.000), information sources (p = 0.044), and the number of children (p = 0.027) with fever self-medication behavior in their children.]]>
<![CDATA[Penggunaan Antibiotik pada ISPA Gambaran Penggunaan Antibiotik pada Anak Dibawah Usia Lima Tahun (Balita) dengan Infeksi Saluran Pernapasan Akut (ISPA) di Puskesmas Kelurahan Tanjung Duren Selatan Tahun 2020-2021: Antibiotik pada ISPA Balita ]]>
<![CDATA[William William]]>;
<![CDATA[Axel Thio Wijaya]]>;
<![CDATA[Donna Mesina Pasaribu]]>;
<![CDATA[Johannes Hudyono]]>
<![CDATA[ Jurnal MedScientiae Volume 1 No 2 : September - Desember 2022 ]]>
Publisher : <![CDATA[Fakultas Kedokteran dan Ilmu Kesehatan Ukrida ]]>
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DOI: 10.36452/jmedscientiae.v1i2.2510
<![CDATA[Acute respiratory infections (ARI) is a disease that attacks the respiratory tract with various symptoms. The biggest cause of ARI is a virus (90-95%), so there is no need for antibiotics because most of the causes of ISP are viruses. Irrational administration of antibiotics can lead to bacterial resistance. The purpose of this study was to describe the use of antibiotics in infants under five years of age with ARI at the Tanjung Duren Selatan Village Health Center in the 2020-2021 period. This research was conducted by descriptive observational on 50 subjects. Sampling by consecutive sampling. The results of this study indicate that the majority of ARI patients have cough symptoms (96%) with an age range of 1-3 years (52%) and birth weight < 15 kg (92%). Complete basic immunization status is only 30%. Most of children under five with ARI (80%) did not get antibiotics and as many as 20% of patients under five with ARI used antibiotics, namely amoxicillin. This study concluded that according to the etiology of ARI in children under five caused by a virus, most of the Toddler patients with ARI not receive antibiotics (80%) and Toddlers who used antibiotics (20%).]]>
<![CDATA[Posisi dan Lama Duduk saat Bekerja dalam Menimbulkan Low Back Pain ]]>
<![CDATA[Hartanto Hartanto]]>;
<![CDATA[Budiman Hartono]]>;
<![CDATA[Theodora Margaret]]>
<![CDATA[ Jurnal MedScientiae Volume 1 No 01 : Mei - Agustus 2022 ]]>
Publisher : <![CDATA[Fakultas Kedokteran dan Ilmu Kesehatan Ukrida ]]>
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DOI: 10.36452/jmedscie.vi.2541
<![CDATA[Low back pain (LBP) is a pain sensation in the L1-S1 region that can radiate to the legs and feet. Position and long time sitting while working are one of the factors that cause LBP. The purpose of this study was to determine the position and long time sitting while working in causing LBP. The method used in the literature study was done by searching in the research journal databases, namely Google Scholar and Pubmed. The results obtained 11 articles that meet the inclusion and exclusion criteria. Sitting upright and hunched over increase complaints of LBP, because it affects the amount of pressure exerted on the spine. This pressure will cause microtrauma accompanied by inflammation, causing LBP. Sitting duration that more than 4 hours is sufficient to cause LBP and the risk of LBP increases when sitting for a longer time, ie 6–9 hours and >9 hours. Sitting for long time will cause the muscles to become tired, reducing muscle support to the spine. This causes the pressure on the ligaments and intervertebral discs to increase. In this literature study also found other factors that can cause LBP, namely: age, chair back, working period and stretching.]]>
<![CDATA[Hubungan Usia dengan Benign Prostate Hyperplasia dan Adenokarsinoma Prostat di Rumah Sakit Bethesda Yogyakarta ]]>
<![CDATA[Jennifer Isabel Roberth]]>;
<![CDATA[Jonathan Willy Siagian]]>;
<![CDATA[Tejo Jayadi]]>;
<![CDATA[Hariatmoko]]>
<![CDATA[ Jurnal MedScientiae Volume 1 No 2 : September - Desember 2022 ]]>
Publisher : <![CDATA[Fakultas Kedokteran dan Ilmu Kesehatan Ukrida ]]>
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DOI: 10.36452/jmedscientiae.v1i2.2549
<![CDATA[Age is a risk factor for the occurrence of Benign Prostate Hyperplasia (BPH) and prostate adenocarcinoma. The prevalence of BPH increases as the size of the prostate gland itself increases in older men. Prostate adenocarcinoma is the most common type of prostate cancer. In 2020, the incidence of prostate cancer is fifth in the male sex. Older men show an increased incidence of BPH and prostate adenocarcinoma compared to younger men. This study was conducted to determine the relationship between age with BPH and prostate adenocarcinoma in Bethesda Hospital Yogyakarta. The design of this study was cross-sectional using 62 medical records belonging to Bethesda Hospital Yogyakarta in 2015-2019 which were taken using the consecutive sampling method. Data were analyzed using Fisher Exact Test and obtained p value=0.048 (p<0.05). The results of this study indicate there is a relationship between age and BPH and prostate adenocarcinoma.]]>
<![CDATA[Pengaruh Pemberian Probiotik pada Infeksi Clostridium Difficile ]]>
<![CDATA[Ade Dharmawan]]>;
<![CDATA[Dhimas Garin Dewa Agista]]>;
<![CDATA[Sinsanta Sinsanta]]>;
<![CDATA[Nicolas Layanto]]>;
<![CDATA[Deby Deby]]>
<![CDATA[ Jurnal MedScientiae Volume 1 No 2 : September - Desember 2022 ]]>
Publisher : <![CDATA[Fakultas Kedokteran dan Ilmu Kesehatan Ukrida ]]>
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DOI: 10.36452/jmedscientiae.v1i2.2567
<![CDATA[Clostridium difficile (C. difficile) is a gram-positive, anaerobic, spore-forming bacterium, and is an important pathogen in antibiotic-associated diarrhea. These bacteria are normal flora in the human digestive tract but can become pathogenic and form toxins consisting of 2, namely toxin A and toxin B. Due to antibiotics including risk factors for C. difficile infection (CDI), the treatment that can be given is probiotics. Probiotics may be effective in the prevention and treatment of CDI in several ways: alteration of gut flora, enhancement of antimicrobial activity, and as immunomodulators. The effect of probiotics, the method of administration, and the varying duration of administration make probiotics unable to be used as a therapy for C. difficile infection. However, probiotics can still be an option for adjuvant therapy in the treatment of CDI.]]>
<![CDATA[Hubungan Indeks Massa Tubuh dengan Kejadian Kanker Prostat dan Gleason Score di Rumah Sakit Siloam Kupang ]]>
<![CDATA[Valerio Christopher Homalessy]]>;
<![CDATA[Shintia Christina]]>;
<![CDATA[Erma Mexcorry Sumbayak]]>
<![CDATA[ Jurnal MedScientiae Volume 1 No 01 : Mei - Agustus 2022 ]]>
Publisher : <![CDATA[Fakultas Kedokteran dan Ilmu Kesehatan Ukrida ]]>
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DOI: 10.36452/jmedscientiae.vi.2571
<![CDATA[Prostate cancer can be termed as the most commonly diagnosed cancer in men. The risk of prostate cancer increases with age. Knowing whether there is a relationship between Body Mass Index (BMI) with prostate cancer and gleason score at Siloam Hospital Kupang. Methods, qualitative research method with cross sectional design and using secondary data from medical records with consecutive sampling technique. Results, patients diagnosed with prostate cancer at Siloam Hospital for the 2017-2021 period were 80 cases and 60 cases were not prostate cancer. The BMI in the group of prostate cancer patients was 54 people (67.5%) in the non-obese group and 34 people (56.67%) in non-prostate cancer. The most cases of prostate cancer with histopathological degrees of High Gleason Score were 45 cases (56.25%), and histopathological degrees of Low Grade Score were 35 cases (43.75). The chi square analysis, it is known that there is no relationship between BMI and the incidence of prostate cancer having a p value = 0.189 (p > 0.05) and the Gleason Score has a p value = 0.764 (p > 0.05). Conclusion there was no relationship between BMI and the incidence of prostate cancer and gleason score at Siloam Hospital Kupang.]]>
<![CDATA[Interferon Gamma sebagai Deteksi Awal Infeksi yang Disebabkan oleh Toxoplasma gondii ]]>
<![CDATA[Monica Puspa Sari]]>
<![CDATA[ Jurnal MedScientiae Volume 1 No 01 : Mei - Agustus 2022 ]]>
Publisher : <![CDATA[Fakultas Kedokteran dan Ilmu Kesehatan Ukrida ]]>
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DOI: 10.36452/jmedscientiae.vi.2572
<![CDATA[Early diagnosis of Toxoplasma gondii infection is crucial for the efficacy of the treatment. The medicine only kill tachyzoite form but not in bradyzoite form that can be found in the cyst. As we know, the shorter the time that we use to detect the infection, the greater the chance of the treatment to success. However, a diagnostic method, the antibody-based serological tests, often is used to detect T. Gondii but have some limitations. Based on recent research, a test known as Interferon-gamma release assay (IGRA), was introduced to detect T. gondii infection. The test was based on T cellin vitro assays and can detect both acute and chronic infections. IGRA can detect the infection as early as day 3, while IgM and IgG serum can be detected on day 9 and 13 post-infection. IGRA accurately distinguish between infected and non infected individuals by showing an activation of lymphocytes after being stimulated via in vitro by T. gondii antigens, even on the first day of life. IGRA is an easy and inexpensivemethod to measure cell mediated immunity to T. gondii. Therefore, IGRA has the potential to be a diagnostic tool for the early detection of T.gondii infection.]]>
<![CDATA[Gambaran Tingkat Pengetahuan Mengenai Anastesi Spinal Operasi Sectio Caesaria pada Wanita Hamil di Klinik Ibu dan Anak ]]>
<![CDATA[Dita Eka Saputri]]>;
<![CDATA[Clara Valentia Josephine]]>;
<![CDATA[Suparto Suparto]]>;
<![CDATA[Eva Oktavia]]>;
<![CDATA[Erma Mexcorry Sumbayak]]>
<![CDATA[ Jurnal MedScientiae Volume 1 No 01 : Mei - Agustus 2022 ]]>
Publisher : <![CDATA[Fakultas Kedokteran dan Ilmu Kesehatan Ukrida ]]>
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DOI: 10.36452/jmedscientiae.vi.2576
<![CDATA[In Indonesia in 2019 there were 4,039,000 deliveries and 921,000 of them used cesarean delivery or around 22.8% of the total number of deliveries. The high prevalence of Sectio caserea contributes to increasing the problems caused by spinal anesthesia. Various complications that can be caused by spinal anesthesia, this requires knowledge of spinal anesthesia so that the mother is not traumatized by undergoing SC surgery. Good knowledge is needed to support postoperative healing behavior. The purpose of this study was to determine the level of insight regarding spinal anesthesia for sectio caesaria surgery in pregnant women at Clinic Maternal & Children. The research method used was quantitative descriptive, with perposive sampling technique of 96 respondents. Methods of data collection using a questionnaire and analyzed descriptively using SPSS. The results showed that the level of knowledge about spinal anesthesia for caesarean section in women at Clinic Maternal & Children was known that most of the respondents had a good level of knowledge as much as 60,4%, sufficient category as much as 30.2% and less category as much as 9,4%.]]>
<![CDATA[Hubungan Pengetahuan, Sikap PHBS terhadap Personal Hygine pada Anak Panti Asuhan Vincentius ]]>
<![CDATA[Ernawaty Tamba]]>;
<![CDATA[Bryan Simanjuntak]]>;
<![CDATA[Wynda Muljono]]>;
<![CDATA[Feby Siburian]]>;
<![CDATA[Izyanie Ain]]>;
<![CDATA[Erma Mexcorry Sumbayak]]>
<![CDATA[ Jurnal MedScientiae Volume 1 No 2 : September - Desember 2022 ]]>
Publisher : <![CDATA[Fakultas Kedokteran dan Ilmu Kesehatan Ukrida ]]>
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DOI: 10.36452/jmedscientiae.v1i2.2577
<![CDATA[In 2014 the realization of PHBS household indicators on personal hygiene in Indonesia was 56.6% lower than the target of 70% with the realization of PHBS household indicators in DKI Jakarta Province of 69.3%. East Jakarta is the area with the lowest percentage of clean and healthy households, which is 33.9% of the 243,438 households monitored. This study was to determine the relationship between knowledge, clean and healthy living behavior and personal hygiene behavior at the Vincentius Orphanage for the period of June 2021. This study used a descriptive-analytic research design with a cross-sectional approach. Questionnaires were distributed and 42 respondents were taken using consecutive sampling technique. The results showed that there was a significant relationship between attitudes towards personal hygiene behavior with p value = 0.014. In addition, there is a significant relationship between the level of knowledge on personal hygiene behavior with a p value = 0.046. While the factors that did not have a significant relationship with personal hygiene behavior were the age and gender of the orphanage children. There is a significant relationship between attitude and level of knowledge on personal hygiene behavior in children at the Vincentius Orphanage in East Jakarta.]]>
