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Jurnal MedScientiae
Published by Universitas Kristen Krida Wacana
ISSN : -     EISSN : 28291166     DOI : https://doi.org/10.36452/jmedscientiae
Core Subject : Health, Science,
Biochemistry, Genetics & Molecular Biology Health Professions Medicine & Pharmacology Nursing Public Health
Jurnal MedScientiae adalah jurnal yang dikelola oleh Fakultas Kedokteran dan Ilmu Kesehatan Universitas Kristen Krida Wacana. Jurnal ini mempublikasikan artikel-artikel secara open access dalam lingkup bidang kedokteran dan kesehatan seperti kedokteran dasar, bioetika kedokteran, biologi sel, biologi molekuler, genetika, fisiologi, biokimia, bioinformatika, anatomi, farmakologi, kesehatan masyarakat, dan ilmu biomedik lainnya.
Arjuna Subject : Kedokteran - Kedokteran (Lain-Lain)
Articles 47 Documents
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Sikap Berdiri Lama Dalam Menimbulkan Nyeri Punggung Bawah Hartanto Hartanto; Budiman Hartono; Ken Millen Nathawira
Jurnal MedScientiae Volume 1 No 2 : September - Desember 2022
Publisher : Fakultas Kedokteran dan Ilmu Kesehatan Ukrida

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (669.639 KB) | DOI: 10.36452/jmedscientiae.v1i2.2661

Abstract

A person's attitude in the work environment, such as sitting, squatting and standing, is often associated with the appearance of low back pain (LBP), but prolonged standing have not been widely discussed in Indonesian journal media. This literature study conducted a search for research articles in the PubMed and Google Scholar journal databases. There were 6 journals which stated that prolonged standing was significantly related to LBP, but 2 other journals stated otherwise. Prolonged standing that exceed 20 minutes can put stress on the posterior muscles of the body and the joints of the vertebral column, especially in the lumbar region which can cause LBP with varying levels and quality of pain. The existence of work factors such as workload, length of work, work attitude, tool assistance, and the number of hours of rest, as well as personal factors, such as age, smoking, gender and BMI, can also influence the appearance of LBP in a person, so that someone who has a longer tenure is at greater risk of experiencing LBP than someone who has a new tenure. These factors can potentially bias research results if they are not carefully prepared.
Current Management of Dry Eye due to The Influence of drugs Maria Vincentia Jessica; Larin Laudita; Kresten Desma Lina; Santi Anugrahsari
Jurnal MedScientiae Vol. 2 No. 1 (2023): April
Publisher : Fakultas Kedokteran dan Ilmu Kesehatan Ukrida

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Abstract

Background, The most common complaints of irritation in the eyes that often bring patients to have their eyes checked are generally associated with dry eyes.  Dry eye disease (DED) is a disease associated with tear film instability due to multifactorial causes where the prevalence of DED with or without symptoms ranges from 5% to 50%.  Factors that cause dry eyes are the use of topical drugs and systemic drugs. Method. This literature review is in the form of a literature review with a descriptive approach. This literature review uses a scientific online databases that support the provision of data on topics raised according to titles, such as PubMed and Google Scholar with the keywords “Current” AND “Management” AND “Dry Eye” AND “Influence of Drugs” Conclusion, one of the factors for dry eye disease can occur due to the influence of drug.. The effect of dry eye is drug factors, namely systemic drugs and topical drugs. Treatment of dry eyes, which can be given artificial tears, increases the volume of the tear film and moisture on the surface of the eye.
Prevalensi Tumor Payudara di RS Hermina Daan Mogot pada Tahun 2017-2021 Febrina Githa Agatha; Shintia Christina; Purnamawati Purnamawati
Jurnal MedScientiae Vol. 2 No. 1 (2023): April
Publisher : Fakultas Kedokteran dan Ilmu Kesehatan Ukrida

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Abstract

Breast cancer is the number one cause of death in developing countries. The purpose of this study was to determine the prevalence and characteristics of breast tumor patients based on histopathological examination at Hermina Daan Mogot Hospital in 2017-2021. This research is an observational descriptive cross-sectional technique regarding breast tumors with parameters such as age, clinical diagnosis and histopathological diagnosis.. In this study, 716 subjects met the inclusion and exclusion criteria. histopathological diagnosis with the most results of mammary carcinoma at the age of 40-49 (40.86%) and the most histopathological diagnosis of fibroadenoma mammary at the age of 20-29 (37.35%). The most common clinical diagnosis consistent with the histopathological diagnosis is fibroadenoma mammary, which is part of a fibroepithelial tumor. The least common clinical diagnosis was papilloma (0.4%) and the least clinical diagnosis was papillary lesion (0.3%), where the papilloma was part of the papillary lesion. Early breast examination is needed to be able to detect malignant lesions at an early stage so that appropriate management can be carried out immediately so as to increase the patient's life expectancy.
Pengaruh Asupan Nutrisi Dan Pola Makan Pada Pasien Dengan Sindrom Ovarium Polikistik Shelly Lesmana; Gracia JMT Winaktu; Irene Maria Elena; Luciana Budiati Sutanto
Jurnal MedScientiae Vol. 2 No. 1 (2023): April
Publisher : Fakultas Kedokteran dan Ilmu Kesehatan Ukrida

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Abstract

Polycystic Ovary Syndrome (PCOS) is a heterogeneous endocrine disorder that is commonly experienced by women of reproductive age worldwide. PCOS is one of the main causes of infertility with many complications such as insulin resistance, ovulatory dysfunction, and hyperandrogenism. Although it is one of the most common causes of infertility in women worldwide, nutritional management for patients with PCOS has not been studied in depth. Therefore, this literature review aims to evaluate and discuss the effect of nutritional intake and diet on PCOS patients. Overall, a low-carbohydrate diet with low-glycemic index and high-unsaturated fats is a good choice of nutritional intake for PCOS patients. In addition, the provision of micronutrient supplements can also play an important role in the nutritional management of PCOS patients.
Tingkat Pengetahuan Masyarakat tentang Penggunaan Antibiotik yang Rasional di Kelurahan Rantepao, Kecamatan Rantepao, Kabupaten Toraja Utara Ary Kristanto Lallo; Yasavati Kurnia Nah; Theresia Citraningtyas
Jurnal MedScientiae Vol. 2 No. 1 (2023): April
Publisher : Fakultas Kedokteran dan Ilmu Kesehatan Ukrida

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Abstract

Antibiotics are medicine used to overcome bacterial infections. Proper use of antibiotics is very important to note because the side effects caused are quite dangerous and improper use of antibiotics can cause antibiotic resistance. This research was conducted to find out how much the level of public knowledge in Malango Sub-district about the rational use of antibiotics. This research is descriptive research with sampling techniques used convenience sampling as many as 100 respondents with questionnaires as the research tool. The data analysis used is univariate measured in the SPSS program. The results of the study found that the level of public knowledge in Malango Sub-disctrict in the use of rational antibiotics arranged by 10% of excellent comprehension. 52% of passable comprehension and 38% of less comprehension. In conclusion, public knowledge in Malango Sub-district tends to enough comprehension.
Profil fitokimia dan aktivitas antioksidan dari minyak atsiri kulit buah Jeruk Pontianak (Citrus nobilis lour. var. Microcarpa): Profil fitokimia dan aktivitas antioksidan dari minyak atsiri C.nobilis Farianti Wiranda; Ika Rahayu; agus Limanto
Jurnal MedScientiae Vol. 2 No. 1 (2023): April
Publisher : Fakultas Kedokteran dan Ilmu Kesehatan Ukrida

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Abstract

Abstract. Citrus nobilis lour fruit. var. microcarpa (C. nobilis) or Pontianak Orange is a food source with good vitamins and antioxidants, while the peel was considered as waste. Along with technological development, people processed it by utilizing its essential oil. Research showed that the essential oil of Pontianak orange peel (C. nobilis) could inhibit the growth of some gram-positive and -negative bacteria. Still, the compounds' composition and antioxidant and anti-inflammatory properties have not been studied much. Therefore, this study aimed to determine the active compound composition, antioxidant, and anti-inflammatory activity of C. nobilis essential oil. The essential oil from C. nobilis peel was extracted using the clavenger method. The GCMS methods was used for active compound profiling. The antioxidant activity of essential oils was examined using the 2,2-diphenyl-1-picrylhydrazyl (DPPH) free radical. The dominant active compound components in C. nobilis essential oil were limonene, β-myrcene, and linalool. The essential oil of C. nobilis had robust antioxidant activity (IC50 13.114 µg/mL) compared to BHT. The content of the dominant active compound in the essential oil supported this activity.
a DETEKSI DINI PRA HIPERTENSI PADA PEKERJA DI RS-FKIK UKRIDA DENGAN ANALISA HEART RATE VARIABILITY: DETEKSI DINI PRA HIPERTENSI PADA PEKERJA DI RS-FKIK UKRIDA DENGAN ANALISA HEART RATE VARIABILITY Yuvensius Gerry Atmaja Gerry; Suparto Suparto; Ronald Winardi Kartika
Jurnal MedScientiae Vol. 2 No. 1 (2023): April
Publisher : Fakultas Kedokteran dan Ilmu Kesehatan Ukrida

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Abstract

The global burden of disease study shows that stroke and ischemic heart disease are the main causes of death and disability in 2017. RISKESDAS 2018 showed that the prevalence of hypertension measured in residents over the age of 18 the increased from 25.8% to 34.1 This is the background of this study on early detection of prehypertension by analyzing heart rate variability in UKRIDA hospital staff. Data collection was performed by an objective sampling technique. There were 81 study samples that met the inclusion and exclusion criteria. As a result, the majority of respondents in the gender category were female, for a total of 43 respondents (53.1%). By age group, 44 people (54.3%) were in the age group of 20-30 years, the most. Subsequently, 29 of her in the professional group were nurses (35.8%). Most of the respondents were normotensive, i.e. 41 respondents (50.6%), and most of the SDNN respondents were of normal height, even 31 respondents (28.4%). The majority of respondents are RSMDD, or normal high, with as many as 23 (28.4%) respondents. HRV influences early detection of prehypertension by SDNN and RMSDD blood pressure results when the correlation test is 0.00 (p-value < 0.05).
KEPARAHAN AKNE VULGARIS DENGAN PENGGUNAAN PROBIOTIK ORAL Elvantie; Arini Astasari Widodo; Budiman Hartono
Jurnal MedScientiae Vol. 2 No. 1 (2023): April
Publisher : Fakultas Kedokteran dan Ilmu Kesehatan Ukrida

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Abstract

Background. Oral probiotics are microorganisms that have various benefits based on theoretical evidence of the skin, brain, and gut. Oral probiotics are an effective choice in the management of acne vulgaris, which has been proven by studies that state that oral probiotics can reduce the degree of acne, inflammatory lesions, non-inflammatory lesions and reduce excess sebum production. Method. The research articles reviewed are in the form of analytical reviews through the PubMed and Google Scholar databases. Results. A total of 6 research articles were selected according to the purpose of writing this literature review. Conclusion. The use of oral probiotics can reduce inflammatory lesions, the degree of severity of acne vulgaris, total inflammatory lesions, and reduce excessive sebum production. Oral probiotics, in some cases, can cause side effects such as gastrointestinal disturbances in the form of bloated. Probiotics are measured in colony-forming units (CFU) which indicate the number of viable cells. The dosage concentration of each probiotic varies, but oral probiotics still provide an effective effect on the treatment of acne vulgaris.
Laporan Kasus: Tantangan Pengelolaan Krisis Hiperglikemia Pasien Penyakit Ginjal Kronik (PGK) Tahap Akhir dalam Hemodialisa Rutin Davin Takaryanto; Maya Kusumawati; Nenny Agustanti; Rudi Supriyadi; Ervita Ritonga; Nanny N. M. Soetedjo; Hikmat Permana
Jurnal MedScientiae Vol. 2 No. 1 (2023): April
Publisher : Fakultas Kedokteran dan Ilmu Kesehatan Ukrida

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Abstract

Introduction Hyperglycemic crisis is a life threatening medical emergency which occur in any individuals, including end stage renal disease (ESRD). The altered renal, glucose, electrolyte, and body fluid dysregulation seen in ESRD patients affects the management. Objective: Hyperosmolar hyperglycemic state (HHS) and diabetic ketoacidosis (DKA) are life threatening hyperglycemic emergencies that warrant immediate and adequate management. The incidence of hyperglycemic crises among ESRD patients who undergo routine hemodialysis remains unknown. Furthermore, several available studies reported in case reports. Methods: We hereby report a case of hyperglycemic crisis of 61years old woman with medical history of type 2 diabetes mellitus (DM) and ESRD as the complication, she undergoes routine hemodialysis. Results: The patient was admitted with decreased consciousness that was preceded by dyspnea, active cough and fever. Then, the patient treated for the hyperglycemic crisis as in ESRD patient and for the with septic shock due to pneumonia. Conclusion: The management of hyperglycemic crises consist of fluid, potasium corection and insulin administration, however there were some adjustment in ESRD patients. At present therere were no spesific guidelines to manage hyperglicemic crisis and ESRD which is challenging.
Manfaat Pemeriksaan Biomarker B-Rapidly Accelerated Fibrosarcoma (BRAF) pada Pasien Preoperatif dengan Kanker Tiroid Edvano Adam Herbudi; Fanny Indarto; Purnamawati
Jurnal MedScientiae Vol. 2 No. 1 (2023): April
Publisher : Fakultas Kedokteran dan Ilmu Kesehatan Ukrida

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Abstract

Thyroid cancer is the most common cancer of the endocrine system. In the detection of thyroid cancer, the gold standard examination is using fine-needle aspiration (FNA), where the cytology results are used in 60% - 80% of cases. FNA examination performed preoperatively determine the initial management of thyroid cancer. However, the FNA technique is limited by insufficient samples in about 2% - 20% of cases and about 10% - 30% of FNA results are classified as indeterminate (ITN) in the Bethesda system. Therefore, molecular tests such as BRAF biomarker screening are expected to help improve the detection of cases in this category. Methods: A literature search conducted from 4 databases (PubMed, ProQuest, ScienceDirect, and Google Scholar) published in the last 10 years with the keywords "preoperative", "braf" or "braf kinases", and "thyroid cancer". Results: Ten studies with total of 11,239 specimens classified in Bethesda III - VI showed increased sensitivity of 34.8% - 96.62% in the combination of FNA and BRAF techniques. Conclusion: The combination of preoperative FNA and BRAF examination increase sensitivity and help in the initial management of thyroid cancer in ITN or Bethesda III and IV group thyroid nodules in the detection of malignancy in the thyroid.

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