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Suryani
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Jurnal Katalisator
Published by Lembaga Layanan Pendidikan Tinggi Wilayah X
ISSN : -     EISSN : 25020943     DOI : https://doi.org/10.22216/katalisator
Core Subject : Science, Agriculture,
Agriculture, Biological Sciences & Forestry Chemistry
Jurnal Katalisator (ISSN Online : 2502-0943) is a journal containing scientific articles through a review by peer reviewers in chemistry. Jurnal Katalisator publishes original manuscripts, short review reviews on the branches of chemistry including: organic chemistry, inorganic chemistry, physical chemistry, analytical chemistry, biochemistry and applied chemistry. The Catalyst Journal is published 2 (two) times a year, April and October
Arjuna Subject : Biokimia, Genetika dan Biologi Molekuler - Biokimia, Genetika dan Biologi Molekuler (Lain-Lain)
Articles 152 Documents
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EFFECTS OF VIRGIN COCONUT OIL SUPPLEMENTATION ON BIOMARKERS OF OXIDATIVE STRESS IN OBESE ADOLESCENTS Suryani; Darius El Febrian; Fitratur Rahmah Agustina; Fitria Mushollini; Diana Angraini; Samnil Astuti Fitri; Aprilya Roza Werdani; Donal Ortega; Ahmad Faridi
JURNAL KATALISATOR Vol. 11 No. 1 (2026): Jurnal Katalisator, Volume 11 No 1 April 2026
Publisher : LLDIKTI X Sumbar, Riau, Jambi, Kepri

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.62769/vcmvsn10

Abstract

Obesity in adolescents is a health problem whose prevalence is closely related to increased oxidative stress. Obesity conditions lead to increased production of reactive oxygen species (ROS) which can trigger lipid peroxidation, cell damage, and various metabolic disorders. Biomarkers of oxidative stress, such as malondialdehyde (MDA) levels and the activity of antioxidant enzymes, namely superoxide dismutase (SOD), glutathione peroxidase (GPx), and catalase (CAT), can be used to assess oxidative stress levels in obese individuals. Virgin Coconut Oil (VCO) is a functional food that contains medium-chain fatty acids (medium-chain triglycerides; MCTs) and phenolic compounds that are thought to have antioxidant and anti-inflammatory activity. The study aimed to analyze the effect of Virgin Coconut Oil supplementation on biomarkers of oxidative stress in obese adolescents. This study uses a quasi-experimental pretest-posttest control group design. A total of 40 obese adolescents aged 15–18 years were divided into two groups, namely the treatment group that received VCO supplementation of 15 mL per day for 8 weeks and the control group that received only balanced nutrition education. The results indicate that VCO supplementation has the potential to increase the body's antioxidant capacity and reduce oxidative stress in obese adolescents. Although the decrease in BMI and waist circumference did not show a statistically significant difference, there was a tendency to improve the anthropometric profile in the group receiving VCO
EFFECT OF WEST SUMATRAN DADIAH ON BODY WEIGHT AND GLYCEMIA IN HYPERGLYCEMIC RATS Meri Wulandari; Ety Yerizel; Harnavi Harun; Efrida
JURNAL KATALISATOR Vol. 11 No. 1 (2026): Jurnal Katalisator, Volume 11 No 1 April 2026
Publisher : LLDIKTI X Sumbar, Riau, Jambi, Kepri

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.62769/bbn89q35

Abstract

This study was a laboratory-based experimental study using a post-test control group design to evaluate the effect of curd administration on body weight and blood glucose levels in hyperglycemic rat model. Male Wistar rats (Rattus norvegicus) aged 8–10 weeks with body weights of 250–300g were used and randomly divided into four groups: a negative control group without diabetes induction or treatment, a positive control group with diabetes induction without therapy, and two treatment groups receiving curd at different doses, P1 (1.8750 g/250 g body weight) and P2 (3.750 g/250 g body weight). The mean body weight was 277.67 g in the negative control group and 227.50 g in the positive control group. Treatment groups showed increased body weights of 246.83 g in P1 and 262.50 g in P2. Blood glucose levels were 125.56 mg/dL in the negative control group and increased to 487.00 mg/dL in the positive control group, while curd administration reduced levels to 122.17 mg/dL in P1 and 101.83 mg/dL in P2. These results indicate that curd improves body weight and lowers blood glucose in hyperglycemic rats, with greater effects at higher doses, suggesting its potential as a functional food for metabolic and glycemic control.

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