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Jurnal Katalisator
Published by Lembaga Layanan Pendidikan Tinggi Wilayah X
ISSN : -     EISSN : 25020943     DOI : https://doi.org/10.22216/katalisator
Core Subject : Science, Agriculture,
Agriculture, Biological Sciences & Forestry Chemistry
Jurnal Katalisator (ISSN Online : 2502-0943) is a journal containing scientific articles through a review by peer reviewers in chemistry. Jurnal Katalisator publishes original manuscripts, short review reviews on the branches of chemistry including: organic chemistry, inorganic chemistry, physical chemistry, analytical chemistry, biochemistry and applied chemistry. The Catalyst Journal is published 2 (two) times a year, April and October
Arjuna Subject : Biokimia, Genetika dan Biologi Molekuler - Biokimia, Genetika dan Biologi Molekuler (Lain-Lain)
Articles 145 Documents
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TUBERCULOSIS: PREVENTION THROUGH INCREASING PUBLIC KNOWLEDGE WITH HEALTH PROGRAM COMMUNICATION EDUCATION Rinda Lestari; Suryani Suryani; Yustitia Akbar; Nova Mustika; Marisa Marisa; Ghufran Aulia; BA Martinus
JURNAL KATALISATOR Vol. 8 No. 2 (2023): Jurnal Katalisator Volume 8 No. 2, Oktober 2023
Publisher : LLDIKTI X Sumbar, Riau, Jambi, Kepri

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.62769/katalisator.v8i2.2626

Abstract

Tuberculosis (TB) is one of the infectious diseases that is still a global health problem. According to World Health Organization (WHO) data in 2020, there are about 10 million new cases of tuberculosis worldwide. TB is still the leading cause of death from infectious diseases in the world, even surpassing the death rate from COVID-19 at the time. In 2019, there were 5,403 TB cases in West Sumatra, in 2019 there were 5,190 TB cases in men (62.70%). Padang is the city with the highest number of TB cases in West Sumatra, with 2,358 cases in 2018, In May 2022, there were 1,500 confirmed TB patients in Padang. Factors contributing to the increase in TB cases in Indonesia, including West Sumatra, are genetics, lifestyle, and level of knowledge. There has been a lot of discussion about tuberculosis, but not many have studied health program communication education about public knowledge about tuberculosis. The purpose of this study was to study health program communication education about public knowledge about tuberculosis. The survey method was used to collect data from respondents representing the community in Padang City. Surveys through written questionnaires and interviews via Google form sent online. Questions in the survey covered aspects such as public knowledge about tuberculosis before and after Promkes education, attitudes towards TB prevention, and factors influencing participation in education programs. The data were analyzed statistically, measuring changes in knowledge before and after Promkes education, and analyzing the factors that influenced the results. Health Program Education Group: Average knowledge about tuberculosis prevention: 8.5 Standard deviation of knowledge: 1.2. Uneducated Group: Average knowledge about tuberculosis prevention: 6.2 Standard deviation of knowledge: 1.5. From the results of the analysis, it can be seen that the group that received Promkes education had a higher average knowledge about tuberculosis prevention compared to the group that did not get education. This difference shows that Promkes education has the potential to have a positive impact on public knowledge about tuberculosis prevention.
KELAYAKAN MASKER KULIT PISANG AMBON DAN BUNGA ROSELLA UNTUK KULIT WAJAH KERING Tiara Salsabila; Hayatunnufus Hayatunnufus
JURNAL KATALISATOR Vol. 8 No. 2 (2023): Jurnal Katalisator Volume 8 No. 2, Oktober 2023
Publisher : LLDIKTI X Sumbar, Riau, Jambi, Kepri

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.62769/katalisator.v8i2.2679

Abstract

Permasalahan kulit kering yang sering terjadi saat ini dan penggunaan kosmetik kimia yang berbahaya bagi kulit. Masker kulit pisang ambon dan bunga rosella terbuat dari dua bahan alami yaitu kulit pisang ambon dan bunga rosella yang dapat dijadikan bahan sediaan masker bubuk tradisional dan terhindar dari zat kimia berbahaya. Penelitian ini bertujuan untuk mengetahui cara pembuatan masker dari kulit pisang ambon dan bunga rosella, untuk menganalisis kelayakan kulit pisang ambon dan bunga rosella ditinjau dari uji laboraturium (kandungan flavonoid, vitamin C, dan uji ph), dan uji organoleptik (tekstur, aroma dan daya lekat) dan uji hedonik (kesukaan panelis). Metode eksperimental laboratorium. Objek penelitian ini adalah kulit pisang ambon dan bunga rosella yang Variabel dalam penelitian ini adalah variabel bebas kulit pisang ambon dan bunga rosella sebagai bahan dasar alami pada sediaan masker kulit pisang ambon dan bunga rosella (X) dan variabel terikat adalah kandungan yang terdapat dalam masker kulit pisang ambon dan bunga rosella (Y). Jenis data menggunakan data primer. Teknik pengumpulan data dilakukan dengan cara observasi, dokumentasi, dan kuesioner. Hasil penelitian ini adalah : 1) Cara pembuatan masker bubuk dari kulit pisang ambon dan bunga rosella, 2) Kelayakan kulit pisang ambon dan bunga rosella sebagai bahan dasar masker dilihat dari hasil pengujian laboraturium positif mengandung flavonoid dan vitamin C dan memiliki pH seimbang yaitu 6.83. 3) Kelayakan masker kulit pisang ambon dan bunga rosella dilihat dari uji organoleptik bahwa tekstur masker yang dinilai sangat halus, aroma dinilai beraroma cukup kuat, daya lekat dinilai sangat melekat saat diaplikasikan dan sebagian besar panelis menyatakan penilaian hedonik (kesukaan panelis) sangat suka dengan masker kulit pisang ambon dan bunga rosella.
EFFECTIVENESS THE OINTMENT OF FOREST BETEL LEAVES EXTRACT (Piper aduncum L. ) AGAINST EXCISION WOUNDS Diza Sartika; Ria Afrianti; Rihadhatul Aisy; Miftahur Rahmi
JURNAL KATALISATOR Vol. 9 No. 1 (2024): Jurnal Katalisator Volume 9 No.1, April 2024
Publisher : LLDIKTI X Sumbar, Riau, Jambi, Kepri

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.62769/katalisator.v9i1.2821

Abstract

Excision wounds are included in open wounds and occupy the top three types of injuries experienced by the public. Forest betel (Piper aduncum L) is one of the plants that can be used in healing excision wounds because it contains several chemical ingredients such as flavonoids, steroids and saponins which can help speed up wound healing. This study aims to determine the effectiveness of ointment extracts of forest betel leaves (Piper aduncum L.) on the healing of excision wounds in male albino rats. Animals are divided into 5 groups there are control group (base used of vaselinflavum ointment), group of forest betel leaf extract concentration 5%, 10%, 15% and the comparison group (Ointment T®). Basting of preparation was done twice a day for 21 days. The parameters observed were the percentage of wound healing, epithelialization time and histopathology. The results showed on the average percentage of excision wound healing on the 7th, 14th and 21st days were control group ( 43.046% , 84.118%, 92.866% ), concentration 5% (45.49%, 87 608%, 94.704%), concentration of 10% (46.196%, 88.24%, 96.692%), concentration of 15% (46.572%, 91.058%, 97.886%) and the comparison group (46.572%, 90.01%, 97.372%). the control group (8 days), 5% concentration (7 days), 10% concentration (6.8 days), 15% concentration (6.4 days) and the comparison group (6.6 days).For the histopathological test, the results of epithelialization, collagen fiber, and fibroblast scores were. respectively the control group (2,2,1), 5% concentration (2,2,2), 10% concentration (2,2,2), 15% concentration (3,3,3) and the comparison group (3 ,3,3). The most effective group for excision wound healing was the 15% concentration group.
TOTAL FLAVONOID LEVELS AND ANTIOXIDANT ACTIVITY OF KERSEN LEAF EXTRACT (muntingia calabura L.) L A, Hamdayani; Fitriyanti Jumaetri Sami; Yuri Pratiwi Utami
JURNAL KATALISATOR Vol. 9 No. 1 (2024): Jurnal Katalisator Volume 9 No.1, April 2024
Publisher : LLDIKTI X Sumbar, Riau, Jambi, Kepri

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.62769/katalisator.v9i1.2831

Abstract

Kersen leaves (Muntingia calabura L.) are plants that contain many secondary metabolites, one of which is flavonoids that can act as antioxidants. This study aims to determine the total content of flavonoids which also have the potential as antioxidants in cherry leaves using the DPPH method (2,2-diphenyl-1-picrylhidrazyl) with various filters, namely 70% ethanol, ethyl acetate and n-hexan. Testing of total flavonoid content was carried out using AlCl3 reagent and measured using spectrophotometry at a wavelength of 422 nm. Antioxidant activity testing was measured at an absorption wavelength of 516 nm. The results showed the total flavonoid content of 70% ethanol filter leaf extract as much as 8.13 (mgQE/g), ethyl acetate as much as 8.32 (mgQE/g) and n-hexan as much as 18.96 (mgQE/g). antioxidant activity of cherry leaves using DPPH method (2,2-diphenyl-1-picrylhidrazyl) with filter variations. 70% ethanol extract of cherry leaves has an IC50 value of 7.56 μg/mL, ethyl acetate extract with an IC50 value of 36.05 μg/mL, and n-hexan extract with an IC50 value of 21.33 μg/mL. From the results obtained it can be concluded that the highest antioxidant activity is contained in 70% ethanol extract of 7.56 μg/mL.
THEORETICAL ANALYSIS OF BINAHONG LEAF EXTRACT AS CORROSION INHIBITOR USING THE DFT METHOD Putri, Yunike; Emriadi; Imelda
JURNAL KATALISATOR Vol. 9 No. 1 (2024): Jurnal Katalisator Volume 9 No.1, April 2024
Publisher : LLDIKTI X Sumbar, Riau, Jambi, Kepri

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.62769/katalisator.v9i1.2858

Abstract

Binahong leaf extract has been experimentally tested containing several compounds that are effective used as corrosion inhibitors. Further computational chemical research was conducted to determine the interaction of the compounds contents, including vitexin, ursolic acid and p-coumaric acid with the iron using the Density Functional Theory (DFT) method based on B3LYP/6-31G. Quantum chemical parameters from optimization results include EHOMO, ELUMO, dipole moment, energy gap (ΔE), electronegativity (χ), ionization potential (I), electron affinity (A), hardness (η), softness (σ), electrophilicity (ω) and nucleophilicity (ε). The interaction strength parameters of the inhibitor with Fe atom, namely charge transfer (ΔN), interaction energy (Δψ) dan back-donation energy (ΔEb-d), indicate that ursolic acid is the best inhibitor molecule. The interaction of inhibitor with Fe (100) seen from the energy of adsorption (Eads) and the bonding energy (Ebinding) suggests that among the three main contents of plant leaf extract, ursolic acid has the highest value of 111.92 kJ/mol with a bond length value of Inh-Fe of 1.91 Å. Binding length data and binding energy indicate that the interaction that occurs is a chemical interaction.
Separation of Anions on Polar Stationary Phases in Hydrophilic Interaction Liquid Chromatography Mayaserli, Dyna Putri; Zein, Rahmiana; Refilda, Refilda; Putra, Adewirli; Toyohide Takeuchi
JURNAL KATALISATOR Vol. 9 No. 1 (2024): Jurnal Katalisator Volume 9 No.1, April 2024
Publisher : LLDIKTI X Sumbar, Riau, Jambi, Kepri

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.62769/katalisator.v9i1.2859

Abstract

The need for the detection of anions and cations in various environmental water samples more rapidly with increasing environmental problems and the time it takes the proper method of analysis, is fast, simple, and can provide an accurate assessment. Hydrophilic Interaction Liquid Chromatography (HILIC) is a highly precise technique for separating polar compounds or hydrophilic compounds. Various places have been making a lot of market columns and columns designed specifically for HILIC. For that to be done selection of the appropriate column to separate compounds primarily for separating anions using polar aminopropyl silica stationary phases, HILIC imidazole, pyridine, and Polar Amide-80. Polar stationary phases are best to separate the anions are aminopropyl silica (NH2-60) because it can separate the anions without adding salt. While Polar pyridine can separate anions at low pH (4.2) using acidic stationary phases and at low pH Polar pyridine can serve as an ion exchanger (ion exchange) Keywords: polar stationary phase, HILIC, ion exchange chromatography
ANTIOXIDANT ACTIVITY OF THE METHANOL EXTRACT OF TURKEY EGGPLANT (Solanum betaceum Cav.) INVITRO Surya, Alfin; Anggi Wulandari; Hesti Marliza; Zaiyar
JURNAL KATALISATOR Vol. 9 No. 1 (2024): Jurnal Katalisator Volume 9 No.1, April 2024
Publisher : LLDIKTI X Sumbar, Riau, Jambi, Kepri

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.62769/katalisator.v9i1.2871

Abstract

Duch Eggplant rich in phytochemicals, such as polyphenols, flavonoids, and carotenoids. Studies have demonstrated the powerful antioxidant activity of these compounds, which can shield body cells from free radical-induced oxidative damage.The aim of this study is to determine the IC50 value of the antioxidant activity present in the skin of the Holland turnip. This study also has implications for human health. Knowing the anti-oxidant skin activity in the inviter allows us to estimate the potential benefits of protecting the body from oxidative damage. 1.1-diphenyl-2-picrylhydrazil (DPPH) is the method employed. This method involves measuring the ability of the extract to neutralize the free radicals in DPPH. We will observe the color changes from purple to yellow and evaluate the free radical's capture capacity based on the degree of color change. The study's findings revealed an IC50 value of 41,019 ppm. The conclusion from the IC50 values obtained is that the methanol extract in the skin of the Dutch teranga has an antioxidant activity that is very strong to counter free radicals. 
PHARMACOKINETIC PROFILE OF SNEDDS PREPARATION EXTRACT OF PUTRI MALU LEAVES Imran, Arlan; Nur’ainun Panigoro; Iksandi Aliwu; Melis Ma’ruf; Rajid Mbuinga
JURNAL KATALISATOR Vol. 9 No. 1 (2024): Jurnal Katalisator Volume 9 No.1, April 2024
Publisher : LLDIKTI X Sumbar, Riau, Jambi, Kepri

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.62769/katalisator.v9i1.2897

Abstract

The Indonesian Ministry of Health reported that incidence of hepatitis in Indonesia has reached 20 million cases. As one of the preventive to reduce hepatitis disease, by consuming natural hepatoprotectors Putri malu plant. Therefore, Putri Malu needs to increase its bioavaibility in the body by making SNEDDS preparations. Purpose of this research is to knowing the formulation of variations in the concentration of oil, surfactant and cosurfactant in the preparation of SNEDDS Putri malu leaf extract on pharmacokinetics including Cpmax, Tmax and T1/2 values. Research method is a laboratory experimental by varying the concentration of VCO: Tween 80: PEG 400, namely F1 (1:6:3), F2 (1:7:2) and F3 (1:8:1). Results : formulation of the SNEDSS of Putri malu leaves has nanoemulsion times at F1-F3 each 3.65, 14.78 and 25.61 seconds. The Cpmax value of the third formula gets a value of 500 ppm, Tmax the three formulas get the same Tmax value of 0 hours and for the T1/2 value at F1-F3 each 4.222, 6836, and  2.826 hours. The best formula is found F2, this can be seen at T1/2, the longer the drug can last in the body, the less frequency of taking the drug.
FORMULATION AND ANTIBACTERIAL ACTIVITY TEST OF ANTI-ACNE GEL FROM ETHANOL EXTRACT OF SENDUDUK LEAVES (Melastoma malabathricum. L) Novelni, Ringga; Mimi Yupelimi; Dina Agustina; Diza Sartika; Vici Syahril Chairani
JURNAL KATALISATOR Vol. 9 No. 1 (2024): Jurnal Katalisator Volume 9 No.1, April 2024
Publisher : LLDIKTI X Sumbar, Riau, Jambi, Kepri

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.62769/katalisator.v9i1.2902

Abstract

Treatment of inflamed acne is done by administering antibiotics and chemicals, which can usually cause side effects such as skin irritation and resistance. To avoid this, it can be replaced by doing traditional treatment using natural ingredients. Senduduk plant (Melastoma malabathricum L.) is one of the natural ingredients that can be used to treat acne because it contains secondary metabolites of flavonoids, phenolics, tannins and terpenoids that are very potential as antibacterials. This study aims to determine the ethanol extract of senduduk leaves can be formulated in a physically stable gel dosage form and determine the antibacterial activity against Propionibacterium acne and Staphylococcus aureus bacteria. This study used an experimental method by making 3 types of formulas containing ethanol extract of senduduk leaves (Melastoma malabathricum L.) 1.5%, 2.5% and 3.5%. Furthermore, the evaluation of the gel preparation included organoleptic test, homogeneity test, pH test, spreadability test and adhesion test. Antibacterial activity testing was carried out by the pitting diffusion method using Klindamycin as a positive control. Based on the results of the gel preparation evaluation, it shows that the anti-acne gel preparation has physical quality that meets the standards. Antibacterial activity test of senduduk leaf ethanol extract gel against S.aureus bacteria at concentrations of 1.5%, 2.5% and 3.5% had inhibition zone diameters of 20.3 mm, 21.4 mm, and 24.2 mm, respectively, while against P. acnes bacteria it was 21.6 mm, 25.3 mm, and 26.5 mm. It can be concluded that the anti-acne gel of senduduk leaf ethanol extract has antibacterial activity against S. aureus and P. acnes bacteria and can be made into an anti-acne gel dosage form.
REMOVAL OF HEAVY METALS USING CHLORELLA VULGARIS: A REVIEW Fitri, Wiya Elsa; Putra, Adewirli; Febria, Fuji Astuti
JURNAL KATALISATOR Vol. 9 No. 1 (2024): Jurnal Katalisator Volume 9 No.1, April 2024
Publisher : LLDIKTI X Sumbar, Riau, Jambi, Kepri

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.62769/katalisator.v9i1.2904

Abstract

In this review, the researchers describe a natural process that can remove heavy metals from the environment. The use of Chlorella vulgaris has more potential than other bioremediation processes. Chlorella vulgaris has been recognized as a biomaterial capable of removal and could be a potential alternative method for the physicochemical absorption of heavy metals. The removal of heavy metals using Chlorella vulgaris on living cells can occur rapidly, independent of absorption of metabolism to the cell surface and intracellular absorption. Non-living cells have also successfully removed heavy metals from liquid waste. As one of the innovative removal technologies, it depends on algae's biosorption and bioaccumulation capabilities, which dominate the bioremediation process. This study shows that the composition of Chlorella vulgaris constituents, such as proteins, lipids, carbohydrates, pigments, vitamins, and minerals, which have various amino acid, hydroxyl, carboxyl, and sulfate functional groups, are the main factors in the absorption process of heavy metals in liquid waste, so they have the potential sustainability in its use as a bio adsorbent in the removal of heavy metals in liquid waste in the future.

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