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Jurnal Katalisator
Published by Lembaga Layanan Pendidikan Tinggi Wilayah X
ISSN : -     EISSN : 25020943     DOI : https://doi.org/10.22216/katalisator
Core Subject : Science, Agriculture,
Agriculture, Biological Sciences & Forestry Chemistry
Jurnal Katalisator (ISSN Online : 2502-0943) is a journal containing scientific articles through a review by peer reviewers in chemistry. Jurnal Katalisator publishes original manuscripts, short review reviews on the branches of chemistry including: organic chemistry, inorganic chemistry, physical chemistry, analytical chemistry, biochemistry and applied chemistry. The Catalyst Journal is published 2 (two) times a year, April and October
Arjuna Subject : Biokimia, Genetika dan Biologi Molekuler - Biokimia, Genetika dan Biologi Molekuler (Lain-Lain)
Articles 145 Documents
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ANTIOXIDANT POTENTIAL OF EXTRACT OF BLACK RICE, BAJAKAH WOOD ROOT AND KEBIUL SEED Yesti, Yulia; Kintoko, Kintoko; Nugraha, Ari Satia; Putra, Billy Harnaldo; Gusriyani, Sri; Saputra, Harry Ade; Alfarisyi, Muhammad Iqbal
JURNAL KATALISATOR Vol. 10 No. 2 (2025): Jurnal Katalisator, Volume 10 No 2 Oktober 2025
Publisher : LLDIKTI X Sumbar, Riau, Jambi, Kepri

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.62769/katalisator.v10i2.3457

Abstract

Exposure to free radicals and oxidative stress are major factors in various degenerative diseases, such as cardiovascular disease, diabetes, cancer, and neurodegenerative diseases. Therefore, the use of natural antioxidant sources is important to reduce the negative effects of free radicals. This study compares the natural antioxidant potential of black rice, bajakah root, and kebiul seeds, whereas previous studies have only identified the antioxidant potential of a single natural ingredient. This study aims to measure the antioxidant potential, such as total polyphenols, total flavonoids, and antioxidant activity, of these three natural materials using distilled water, 70% ethanol, and 96% ethanol as solvents. The experimental research method involved testing antioxidant activity and measuring total phenolics and flavonoids. The results showed that the 70% ethanol extract of black rice had the highest total polyphenol content at 6.83±0.28 mgGAE/g (0.007±0.00%), the 70% ethanol extract of bajakah wood root had the highest flavonoid content at 8.77±0.02 mgQE/g (0.009±0.00%), and the distilled water extract of kebiul seeds showed the strongest antioxidant activity based on an IC50 value of 5.96 ± 0.01 ppm. This study concluded that black rice has potential as a primary source of phenolics and anthocyanins, while bajakah wood root and kebiul seeds are sources of flavonoids with strong antioxidant activity.
Α-GLUCOSIDASE ENZYME INHIBITOR ACTIVITY OF ETLINGERA ELATIOR LEAF EXTRACT WITH SOLVENT VARIATION Imrawati Imrawati; Yuri Pratiwi Utami; Yuniar Dwi Yanti; Tuti Handayani; Nurzadrina wahyuddin; Zahira Amody; Aulia Debby Pelu; Rahmah Mustarin; Indri Indri
JURNAL KATALISATOR Vol. 10 No. 2 (2025): Jurnal Katalisator, Volume 10 No 2 Oktober 2025
Publisher : LLDIKTI X Sumbar, Riau, Jambi, Kepri

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.62769/katalisator.v10i2.3462

Abstract

Diabetes mellitus (DM) is a chronic metabolic disease characterized by hyperglycemia due to impaired insulin production or utilization. The increasing prevalence of diabetes, especially type 2, is a global concern due to the risk of complications it poses. One approach in treating type 2 diabetes is to inhibit the α-glucosidase enzyme to slow down glucose absorption. This research aims to identify the potential of patikala leaf extract as an α-glucosidase enzyme inhibitor. Using an experimental method with patikala leaf samples collected from Mariri Hamlet, Banyuurip Village, Bone-bone District, North Luwu Regency. Extraction was performed using the maceration method with variations in solvents: 70% ethanol, ethyl acetate, and n-hexane. The α-glucosidase enzyme inhibition activity was measured using a microplate reader and analyzed to determine the IC50 value. From the percentage inhibition data, the IC50 values obtained for 30% ethanol extract of patikala leaves were 351.95 µg/mL, for 70% ethanol extract of patikala leaves were 444.83 µg/mL, for 96% ethanol extract of patikala leaves were 362.27 µg/mL, for ethyl acetate extract of patikala leaves were 163.59 µg/mL, and for n-hexane extract of patikala leaves were 294.90 µg/mL, indicating that patikala leaf extracts with variations in solvent or extraction method exhibited very weak α-glucosidase enzyme inhibition activity. In conclusion, based on the research results obtained, the extract with variations in the solvent or extractant. Patikala leaf extract has an inhibitory activity against the α-glucosidase enzyme, which is categorized as very weak because it has an IC50 value > 100 µg/mL. In comparison, the control (acarbose) is in the weak category with an IC50 value of 50-100 µg/mL.
ANTIOXIDANT ACTIVITY OF SOURSOP (ANNONA MURICATA L.) LEAF JELLY CONFECTIONS FORMULATED WITH MULTIPLE GEL MATRICES Jumalia Aswar; Dewi Yuliana; Nasrul Haq; Zufiayu Sapiun; Abdul Rasyid, Faradiba
JURNAL KATALISATOR Vol. 10 No. 2 (2025): Jurnal Katalisator, Volume 10 No 2 Oktober 2025
Publisher : LLDIKTI X Sumbar, Riau, Jambi, Kepri

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.62769/katalisator.v10i2.3463

Abstract

Jelly confections represent promising nutraceutical products by incorporating bioactive compounds with health-promoting properties. Soursop leaves (Annona muricata L.) are recognized as a potential source of antioxidant and antibacterial agents, yet their application in functional foods remains limited. This study evaluated the antioxidant activity of soursop leaf jelly confections prepared with different gel matrix combinations. Formulation optimization was carried out using three gel matrices, namely carrageenan: agar (9:6), carrageenan: konjac (5:1), and konjac: agar (7:3). Antioxidant activity was assessed by the 2,2-diphenyl-1-picrylhydrazyl (DPPH) radical scavenging assay using a microplate reader spectrophotometer. The results demonstrated IC₅₀ values of 28.95 µg/mL for carrageenan: agar, 8.82 µg/mL for carrageenan: konjac, and 30.33 µg/mL for konjac: agar formulations. Among these, the carrageenan: konjac (5:1) formulation exhibited the most potent antioxidant activity, indicating its potential for developing functional jelly-based nutraceuticals.
ASPARTATE TRANSAMINASE IN CHRONIC HEPATITIS B PATIENTS AT AWALBROS BATAM HOSPITAL Suryani, Suryani; Dwika, Nubbeliano; Lestari, Rinda; Abrar, Mardhatillah
JURNAL KATALISATOR Vol. 10 No. 2 (2025): Jurnal Katalisator, Volume 10 No 2 Oktober 2025
Publisher : LLDIKTI X Sumbar, Riau, Jambi, Kepri

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.62769/katalisator.v10i2.3477

Abstract

Chronic hepatitis B (HBV) is a liver infection characterized by persistent replication of Hepatitis B virus (HBV). Viral load is a parameter often used to evaluate viral replication activity, while Alanine Transaminase (ALT) and Aspartate Transaminase (AST) often used as biomarkers to assess liver damage. Objective: This study aims to evaluate the correlation of HBV viral load to ALT and AST in patients with chronic hepatitis B at Awalbros Batam Hospital. Methods: This research used descriptive study by data collected from patients with chronic hepatitis B who had undergone testing assessments of HBV viral load, ALT and AST. Results: The results of this study is indicate a significant correlation of HBV viral load to ALT levels. Approximately 40% of patients showed elevated ALT levels in line with increasing HBV load, while AST increase was observed in only about 5% of patients. The stronger correlation was noted in ALT, likely due to its higher specificity to liver tissue compared to AST. Conclusion: Quantitative HBV load significantly influences ALT levels but has a less notable effect on AST levels. These findings support the role of ALT as a more reliable indicator of chronic HBV infection. The study also simplifies the clinical phases of infection into two main categories: active and inactive, based on presumed similarities in clinical patterns.  
ADSORPTION STUDY OF LEAD (Pb²⁺) IONS USING CASSAVA PEEL BIOCHAR: EFFECT OF pH AND CONTACT TIME Elfia, Mega; Etriyanto Arman; Eduwin Saputra; Alfin Surya; Yoravika Dwiwibangga; Vicka Andini; Aidil Onasis; Nadya Br Debora
JURNAL KATALISATOR Vol. 10 No. 2 (2025): Jurnal Katalisator, Volume 10 No 2 Oktober 2025
Publisher : LLDIKTI X Sumbar, Riau, Jambi, Kepri

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.62769/katalisator.v10i2.3484

Abstract

This study evaluates the adsorption performance of NaOH-activated cassava peel biochar (Manihot esculenta Crantz) for the removal of Pb²⁺ ions from aqueous solutions, with particular focus on the effects of solution pH and contact time. Cassava peel biochar was produced via pyrolysis at 180–350 °C and chemically activated using 0.1 M NaOH. Surface functional groups and morphology were characterized using Fourier Transform Infrared Spectroscopy (FTIR) and Scanning Electron Microscopy–Energy Dispersive X-ray (SEM–EDX). Batch adsorption experiments were conducted by varying solution pH (3–8) and contact time (30–120 min), while Pb²⁺ concentrations before and after adsorption were analyzed using Atomic Absorption Spectroscopy (AAS). The results showed that solution pH significantly affected Pb²⁺ adsorption, with the highest adsorption capacity of 9.94 mg/g achieved at pH 5. Contact time also influenced adsorption performance, and the optimum condition was obtained at 90 min, yielding a maximum adsorption capacity of 9.94 mg/g. These findings indicate that NaOH-activated cassava peel biochar exhibits stable and effective Pb²⁺ adsorption under slightly acidic conditions and moderate contact time, highlighting its potential as a low-cost and environmentally friendly adsorbent for Pb²⁺ removal from contaminated wastewater.

Page 15 of 15 | Total Record : 145

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