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Media Dermato-Venereologica Indonesiana

mdvi
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Published by Perhimpunan Dokter Spesialis Kulit dan Kelamin Indonesia

ISSN : - EISSN : 26567482 DOI : https://doi.org/10.33820/mdvi.v49i3

Core Subject : Health,

Health Professions

Media dermato Venereologica Indonesiana adalah jurnal open access dan peer-reviewed yang fokus di bidang dermatologi dan venereologi. Jurnal ini menerbitkan artikel asli, laporan kasus, tinjauan pustaka dan komunikasi singkat mengenai kesehatan kulit dan kelamin, diagnosis dan terapi pada bidang kulit dan kelamin dan masalah lainnya di bidang kesehatan kulit dan kelamin.

Arjuna Subject : Kedokteran - Dematologi

Articles 282 Documents

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PIODERMA GANGRENOSUM MULTIPEL DAN BERULANG
Media Dermato Venereologica Indonesiana Vol 49 No 2 (2022): Media Dermato-Venereologica Indonesiana
Publisher : PERDOSKI

Pyoderma gangrenosum is a rare, non-infectious inflammatory skin disease. Diagnosis and treatment are challenging since there are no specific diagnostic criteria or gold standard therapy. The case of a 73 years old man, consulted by surgery department with painful and rapidly progressive necrotic ulcer on his left lower limb and right arm. The initial diagnosis was bacterial ulcer, he underwent debridement and received antibiotics. In the few days, his wound had worsened with enhanced in size and extremely painful. Histological examination showed a dense dermal infiltrate of neutrophil (predominant), lymphocyte, and plasma cell; conformable to pyoderma gangrenosum. Injection of methylprednisolone 31.25 mg / day and mometasone furoate cream 0.1% was given. Clinical improvement was noted in 2 weeks after therapy. Two years later, he developed typical necrotic ulcer on right limb. Pyoderma gangrenosum must be considered in any patient with painful and rapidly progressive ulcer that do not respond to broad-spectrum antibiotics. The histological findings can rule out the other causes of cutaneous ulcer. Suppression of inflammatory process is the main goal in therapy. The delay in identify, inappropriate treatment, and recurrence of the disease remain an issue.

KEGAGALAN TERAPI PADA KUSTA TIPE LEPROMATOSA DAN FAKTOR YANG MEMENGARUHINYA: SEBUAH LAPORAN KA
Media Dermato Venereologica Indonesiana Vol 49 No 2 (2022): Media Dermato-Venereologica Indonesiana
Publisher : PERDOSKI

Children is a group that is nine times more likely to contract leprosy. The finding of new cases of leprosy in children is a strong indicator that indicates the disease transmission is still ongoing. World Health Organization (WHO) in 2019 reported 14,981 out of 202,185 (7.4%) new cases of children. Cases of resistance to multidrug therapy (MDT) can be primary or secondary. It is important to detect drug resistance earlier considering children’s quality of life would be affected by leprosy complication. A 14 years old girl from Lebak Regency, Rangkasbitung, Banten was diagnosed as lepromatous type (LL) leprosy and a second grade disability on the 5th finger of her left hand. Unimproved clinical and increasing the morphological index (IM) on the 9th month of treatment from 0.16% to 1%, leading the patient experience the drug resistance. The polymerase chain reaction (PCR) examination did not show any mutation in the RpoB gene. Inadequate and irregular MDT consumption have the potential to cause secondary resistance and the risk of becoming primary resistance later. It is not easy to determine drug resistance in endemic areas. Morphological index monitoring should be closely watched before treatment is complete thus the modified therapy can be given earlier.

DIAGNOSIS DAN TATA LAKSANA KEKAMBUHAN KUSTA
Media Dermato Venereologica Indonesiana Vol 49 No 2 (2022): Media Dermato-Venereologica Indonesiana
Publisher : PERDOSKI

Leprosy relapse is defined as the reappearance of leprosy’s signs and symptoms following completion of adequate Multidrug Therapy (MDT) regimen. Indonesia is the third biggest contributor for leprosy relapse with 284 cases in 2018. Several factors contribute to the occurrence of relapse, which include presence of persisters, history of inadequate therapy, drug resistance, history of irregular treatment, history of dapsone monotherapy, high initial bacteriological index, high number of skin and nerve lesions, negative lepromin test, history of antireaction therapy, human immunodeficiency virus (HIV) infection, and pregnancy. Diagnosis of relapse can be established based on clinical, bacteriological, and therapeutic criteria, also histopathological and serological criteria, if possible. With those criteria, it should be easier to differentiate relapse from reaction, resistance, reactivation, and reinfection. The principal management for leprosy relapse is re-administration of MDT according to the type of relapse; however, therapy should be modified if there are any evidences of drug resistance. Things which are important to be taken into account during relapse treatment are leprosy type, past medication history, and the possibility of drug resistance. With proper knowledge and diagnostic algorithm, it is expected that the treatment can be administered immediately in order to prevent disability and transmission of infection.

ALOPESIA AREATA SEBAGAI SEKUELE POST REINFEKSI COVID-19
Media Dermato Venereologica Indonesiana Vol 49 No 3 (2022): Media Dermato-Venereologica Indonesiana
Publisher : PERDOSKI

Pendahuluan: COVID-19 merupakan suatu pandemi global yang menyebabkan morbiditas dan mortalitas yang belum pernah terjadi sebelumnya. Selain gejala pernapasan, manifestasi dermatologikus juga telah dilaporkan secara luas, dengan manifestasi dominan berupa kerontokan rambut. Ilustrasi kasus: Seorang laki-laki berusia 32 tahun mengalami kebotakan setempat pada area vertex kepala yang muncul 1 bulan setelah mengalami infeksi kedua SARS-CoV-2. Riwayat gangguan autoimun dan kebotakan disangkal. Pemeriksaan trikoskopi ditemukan gambaran yellow-dots, black-dots, broken-hairs, dan exclamation-mark hairs. Pasien diobati dengan minoxidil dan tretinoin topikal selama tiga bulan dengan respons yang sangat baik. Diskusi: Infeksi COVID-19 dan stress psikologis akibat infeksi COVID-19 dapat memicu alopesia areata (AA). Infeksi COVID-19 menginduksi aktivasi kaskade sitokin yang melibatkan interferon sehingga mengganggu hair follicle immune privilege (HFIP). Sementara itu, stress psikologis juga meningkatkan peradangan neurogenik dan beralih ke respons imun sel T-helper tipe 1 yang memengaruhi pertumbuhan rambut. Terdapat tiga laporan sebelumnya mengenai AA onset baru paska infeksi COVID-19 dan laporan kami adalah satu-satunya AA onset baru paska reinfeksi COVID-19. Kesimpulan: Laporan kami mengenai AA onset baru paska reinfeksi COVID-19 memberikan wawasan tentang kemungkinan hubungan antara infeksi COVID-19 dan AA. Timbulnya AA pada pasien COVID-19 merupakan gejala sisa/sekuele paska COVID-19 yang disebabkan oleh respon imun atau tekanan psikologis.

PENGARUH DARI PEMBERIAN PROBIOTIK LACTOBACILLUS PLANTARUM DALAM TATA LAKSANA DERMATITIS ATOPIK
Media Dermato Venereologica Indonesiana Vol 49 No 3 (2022): Media Dermato-Venereologica Indonesiana
Publisher : PERDOSKI

Lactobacillus plantarum merupakan probiotik yang berasal dari makanan tradisional Indonesia yaitu dadih sapi yang diisolasi. Fungsi probiotik bisa menurunkan reaksi alergi. Dermatitis atopik adalah peradangan kulit yang bersifat kronik residif yang disertai dengan gejala alergi. Penelitian ini untuk mencari pengaruh pemberian probiotik Lactobacillus plantarum pada tata laksana dermatitis atopik dengan melihat index SCORAD, efektifitas pemberian secara single atau campuran, dan efek samping probiotik. Metode yang digunakan pada penelitian ini adalah studi literatur. Populasi pada penelitian ini adalah artikel penelitian tentang probiotik dan dermatitis atopik dengan sampel diambil dari 10 artikel pada jurnal internasional yang terindeks SCIMAGO dengan tahun publikasi dari tahun 2017 hingga 2022. Hasil penelitian ini menunjukkan adanya penurunan indeks SCORAD secara signifikan pada pemberian probiotik. Pemberian secara campuran terdapat penurunan indeks SCORAD secara siginifikan. Hasil penelitian ini menyatakan pemberian probiotik dinilai aman dan tidak menimbulkan efek samping. Kesimpulan penelitian ini probiotik Lactobacillus plantarum berpengaruh dalam tata laksana dermatitis atopik.

OKRONOSIS EKSOGEN: PEMBAHARUAN DALAM DIAGNOSIS DAN TATA LAKSANA
Media Dermato Venereologica Indonesiana Vol 49 No 1 (2022)
Publisher : PERDOSKI

Exogenous ochronosis is a skin disorder characterized by blue-black or greyish pigmentation with the histological appearance of brownish-yellow deposits of polymerized homogentisic acid (HGA) in the dermis. Exogenous ochronosis is common in dark-skinned individuals, but recent studies have shown that the disease can also occur in ethnic Asians in China, Thailand, and Singapore. The majority of exogenous ochronosis occurs due to the continuous use of topical hydroquinone for a long period of time. The clinical picture of exogenous ochronosis can be different, according to the stage classification. Skin biopsy is an invasve procedure for diagnosing exogenous ochronosis, the standard gold examination with the histological appearance of yellow-brown or green banana-shaped fibres in the dermis. Dermoscopy is one of the latest non-invasive tools that can help diagnose exogenous ochronosis from other hyperpigmented lesions. Dermoscopy examination showed an arciform curvilinear (worm-like pattern) appearance with telangiectasia with grey-blue dots and globules with a caviar-like appearance. Exogenous ochronosis remains a challenging condition to treat. Several therapeutic modalities, such as topical and laser therapy, are available. The European Society of Laser Dermatology (ESLD) recommends laser therapy as the latest therapy in the management of exogenous ochronosis with the principle of fractional ablative modality. However, no single therapeutic modality is consistently satisfactory.

PERAWATAN KULIT ANAK DENGAN DERMATITIS ATOPIK
Media Dermato Venereologica Indonesiana Vol 49 No 1 (2022)
Publisher : PERDOSKI

Atopic dermatitis (AD) is a very itchy, chronic residual skin inflammation often found in children, thus affecting the quality of life of patients and their families. The pathogenesis of AD is complex and multifactorial, with the primary pathological state being a skin barrier disorder that may induce acute exacerbations. Skincare in AD patients is one of the nonpharmacological measures to repair the skin barrier and prevent a recurrence. The use of mild cleansers, the routine use of moisturizers, the choice of clothing materials, breaking the scratch-itch cycle, and eliminating trigger factors are a series of skincare that have been researched for their clinical benefits in skin barrier disorders. The management of AD patients requires a holistic approach followed by integrating evidence-based skincare and pharmacologic therapy. Improving the pathological skin barrier is the basic principle in managing AD patients. Implementing proper skincare for AD in children needs the help and support of their parents. It is hoped that the adherence, independence, and improvement of the quality of life of patients and their families are expected to be achieved.

MUNGKINKAH COVID-19 MENULAR MELALUI KONTAK SEKSUAL ?
Media Dermato Venereologica Indonesiana Vol 49 No 1 (2022)
Publisher : PERDOSKI

The widespread Covid-19 outbreak has raised many questions about the origin and transmission of the virus. It has now been proven that it can be transmitted through droplets, physical contact and aerosols. Additionally, several other possible modes of transmission are being explored. The discovery of SARS-CoV-2 and ACE2 in male and female reproductive organs, raises suspicions of the possibility of transmitting Covid-19 through sexual contact. The main purpose of this paper is to review the existing literature on possible modes of transmission of Covid-19, primarily through sexual contact; also to develop an understanding of the causes and spread of SARS-CoV-2, and to suggest recommendations for containing and preventing the spread of new coronavirus. An assessment of possible modes of transmission of SARS-CoV-2 was carried out based on reports and articles available on PubMed and ScienceDirect.com with keywords, ‘transmission’, ‘sexual contact’, ‘Coronavirus’, ‘SARS-CoV-2’, and ‘Covid-19’. Various studies have shown different results regarding the presence of SARS-CoV-2 in the reproductive organs of both men and women, some found SARS-Cov-2 in kidney, anal, semen, and vaginal fluids; but some other researchers did not find. Likewise, the existence of the ACE2 receptor in the reproductive organs as a receptor that determines a person's susceptibility to infection, the results are controversial. A long study is still needed to be able to conclude whether Covid-19 can be transmitted through sexual contact. The experts advise someone affected by Covid-19 to postpone close contact, including sexual contact, always maintain personal and environmental hygiene, also adhering to health protocols.

HEMANGIOMA INFANTIL
Media Dermato Venereologica Indonesiana Vol 49 No 1 (2022)
Publisher : PERDOSKI

Infantile hemangiomas (IH) are the most common benign vascular tumors in infancy and childhood. Hemangiomas may be present at birth, but most develop in the ﬁrst few weeks after birth. Classification is used to differentiate the location of the lesion namely superficial, deep or mixed type. The pathogenesis of HI has not yet been fully explained. Although it is still under debate, it is concluded that placental angioblast embolic or intrinsic endothelial progenitor cells have the ability to proliferate clonal under the influence of appropriate cytokines. Infantile hemangiomas are distinguished from other vascular tumors and malformations by their unique growth pattern (rapid proliferative phase with subsequent slower involution. Studies have shown that in the proliferative phase, there is an imbalance of angiogenic and vasculogenic. As hemangioma could regress spontaneously, it generally does not require treatment unless proliferation interferes with normal function or gives rise to risk of serious disﬁgurement. Severe cases that require treatment are considered due to location or distribution, life threatening (subglottic, multifocal with visceral involvement), impaired function (periorificial), causing severe ulceration and bleeding (lumbosacral, genital) or risk of permanent disability (central facial, breast). Historic treatment options for IH include corticosteroids, beta blockers, surgery, lasers, or a combination of these therapies.

PENGGUNAAN PELEMBAP PADA BAYI BERISIKO TINGGI TERHADAP INSIDENS DERMATITIS ATOPIK INFANTIL: SEBUAH TELAAH SISTEMATIK
Media Dermato Venereologica Indonesiana Vol 47 No 4 (2020)
Publisher : PERDOSKI

Introduction: Atopic dermatitis is a relapsing chronic inflammatory skin disease, 15-20% occurring in children. Heredity in the family is the most crucial risk factor for the incidence of atopic dermatitis. Therefore, improving the barrier function of the skin as early as possible in high-risk infants may be an option as primary prevention for atopic dermatitis. Objective: Conducting a systematic review of randomized controlled trials (RCT) that test the effects of giving moisturizers to high-risk infants and the incidence of infantile atopic dermatitis. Methods: A literature search was carried out through three electronic databases: PubMed, Cochrane, and Embase. Those articles were critically reviewed and assessed for the risk of bias using the Cochrane Risk of Bias Tools. Results: After a critical review of the full text, there were 4 RCT articles. Those four articles found a similar outcome: the incidence of atopic dermatitis was lower in the intervention group. Discussion: The link between heredity and the incidence of atopic dermatitis in children forms the basis of inclusion criteria for samples in this systematic review. Moisturizer administration has been shown to improve TEWL values and stratum corneum hydration. Conclusion: The use of moisturizers in high-risk infants may be considered as one of the preventive interventions for atopic dermatitis. However, further research is needed to support this hypothesis.

Page 14 of 29 | Total Record : 282

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Contact Name Sonia Hanifati

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Editorial Address Ruko Grand Salemba Jalan Salemba 1 No.22, Jakarta Pusat, Indonesia

Location Kota adm. jakarta pusat, Dki jakarta INDONESIA

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Contact Name
Sonia Hanifati

Contact Email
soniahanifati@gmail.com

Phone
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Journal Mail Official
mdvi.perdoski@gmail.com

Editorial Address
Ruko Grand Salemba Jalan Salemba 1 No.22, Jakarta Pusat, Indonesia

Location
Kota adm. jakarta pusat,

Dki jakarta

INDONESIA