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INDONESIA
Jurnal Penyakit Dalam Indonesia
Published by Universitas Indonesia
ISSN : 24068969     EISSN : 25490621     DOI : https://doi.org/10.7454/
Core Subject : Health,
Medicine & Pharmacology
Jurnal Penyakit Dalam Indonesia contains the publication of scientific papers that can fulfill the purpose of publishing this journal, which is to disseminate original articles, case reports, evidence-based case reports, and literature reviews in the field of internal medicine for internal medicine and general practitioners throughout Indonesia. Articles should provide new information, attract interest and be able to broaden practitioners insights in the field of internal medicine, as well as provide alternative solutions to problems, diagnosis, therapy, and prevention.
Arjuna Subject : Kedokteran - Kedokteran Internal
Articles 423 Documents
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Manfaat Latihan Kekuatan Otot terhadap Kadar HbA1c pada Orang Dewasa dengan Prediabetes: Laporan Kasus Berbasis Bukti Simanjuntak, Owen Paruhum; Lubis, Anna Mira
Jurnal Penyakit Dalam Indonesia
Publisher : UI Scholars Hub

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Abstract

Prediabetes is a metabolic condition of impaired glucose homeostasis which results in elevated blood glucose levels. Besides the higher risk of developing diabetes, prediabetes is associated with increased risk of cancer, dementia, heart failures, and coronary artery disease. The common first line treatment regimen given to this group are healthy diet and aerobic exercise. However, some conditions might prevent patients from doing aerobic exercises therefore there is a need for alternatives. This evidence-based case report aims to evaluate the benefit of resistance training on HbA1c levels compared to control group (no exercise) in prediabetic adults. Literature search was conducted across several databases (PubMed, Cochrane, Scopus, and Wiley). Included articles are then critically appraised with the Oxford Center for Evidence-Based Medicine (CEBM) tool. Levels of evidence for each included study are assessed with the Oxford CEBM 2011 levels of evidence table.  Out of 658 studies screened, 15 studies were selected and 2 were included. A systematic review and meta-analysis found that resistance training with low-to-moderate load resulted in a significant reduction of HbA1c compared to the control group. A randomized controlled trial (RCT) also found significant reduction in HbA1c levels after 12 and 24 months of resistance training, compared to the control group. However, study found that resistance training with high load does not significantly reduce HbA1c levels. Current evidence supports the regimen of low-to-moderate resistance training (performed three times per week for 50-60 minutes per session at an intensity of 50-75% of one-repetition maximum) to lower HbA1c levels in adult prediabetic populations.
Koeksistensi Spondiloartritis Perifer dan Fokal Segmental Glomerulosklerosis: Sebuah Laporan Kasus Jarang Zulaifah, Zakiya; Hapsari, Florentina Carolin Puspita; Muzellina, Virly Nanda
Jurnal Penyakit Dalam Indonesia
Publisher : UI Scholars Hub

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Abstract

Spondyloarthritis is a group of inflammatory rheumatic diseases characterized by shared clinical features, genetic predispositions, and pathogenic mechanisms. Without appropriate management, it carries a risk of various complications. We report the case of a young male patient with a one-year history of nephrotic syndrome prior to admission, presenting with chronic polyarthritis. Initially, systemic lupus erythematosus (SLE) with renal and musculoskeletal involvement was suspected, although SLE is relatively uncommon in young males. However, based on the clinical presentation of arthritis, imaging findings of sacroiliitis, and the absence of diagnostic criteria supporting SLE, the patient was subsequently diagnosed with peripheral spondyloarthritis and nephrotic syndrome secondary to focal segmental glomerulosclerosis (FSGS). Patients with spondyloarthritis have approximately a twofold increased risk of renal complications compared with the general population, with IgA nephropathy being the most common abnormality. Although rare, cases of spondyloarthritis occurring in patients with FSGS have been reported. The relationship between these two conditions remains unclear—whether causal or coincidental—and warrants further investigation. A careful diagnostic approach is essential in patients with chronic polyarthritis, particularly when differential diagnoses do not align with demographic characteristics or clinical presentation. This is crucial to improve diagnostic accuracy, guide appropriate therapy, enable earlier prevention of disease progression, and reduce the risk of complications.
Campak dan Vaksinasi Campak pada Orang Dewasa Sinto, Robert; Koesnoe, Sukamto; Nelwan, Erni Juwita; Widhani, Alvina; Shakinah, Sharifah; Pasaribu, Adeline; Duindrahajeng, Bernadine Gracia; Suwarto, Suhendro; Nainggolan, Leonard; Chen, Lie Khie; Susilo, Adityo; Maria, Suzy; Hasibuan, Anshari Saifuddin; Wicaksana, Bramantya
Jurnal Penyakit Dalam Indonesia
Publisher : UI Scholars Hub

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Abstract

Measles is a highly contagious viral infection that remains a significant global health problem despite the availability of an effective vaccine. Measles re-emergence is driven by gaps in immunization coverage, waning post-vaccination immunity, and increased population mobility. In adults, measles infection is associated with greater disease severity compared to children. This literature review was conducted by reviewing recent scientific publications addressing the epidemiology, pathogenesis, clinical manifestations, diagnosis, management, complications, and prevention of measles, with a focus on the adult population.  Measles is caused by an RNA virus of the Paramyxoviridae family and is transmitted through respiratory droplets and aerosols. Typical clinical features include fever, cough, coryza, conjunctivitis, and a maculopapular rash with a centrifugal and cephalocaudal distribution. Diagnosis is based on clinical findings and confirmed by laboratory tests such as RT-PCR and measles-specific IgM serology. Measles infection causes significant immunosuppression, including immune amnesia, which increases susceptibility to secondary infections. Management is primarily supportive and vitamin A supplementation has been shown to reduce mortality in certain populations. In adults, complications tend to be more severe, particularly pneumonia as the leading cause of morbidity and mortality, as well as neurological complications such as encephalitis and subacute sclerosing panencephalitis (SSPE). Measles vaccination with the MMR vaccine remains the main prevention strategy. However, its implementation faces challenges, including gaps in immunization coverage, vaccine hesitancy, and limited adult immunization record system. Measles in adults remains a significant health concern with a high risk of severe complication. Strengthening immunization program, improving public education, and developing integrated surveillance system are essential to reduce disease incidence and burden.

Page 43 of 43 | Total Record : 423

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