cover
Contact Name
Kuntaman
Contact Email
jcmidpamki@gmail.com
Phone
+6281337051550
Journal Mail Official
jcmidpamki@gmail.com
Editorial Address
Departemen Mikrobiologi, Fakultas Kedoteran Universitas Airlangga, Jl. Prof. Dr. Moestopo 47 Surabaya 60286
Location
Kota surabaya,
Jawa timur
INDONESIA
Journal of Clinical Microbiology and Infectious Diseases
ISSN : -     EISSN : 28089405     DOI : https://doi.org/10.51559/jcmid
Core Subject : Science,
Journal of Clinical Microbiology and Infectious Diseases; peer-reviewed journal aiming to communicate high-quality research articles, reviews, and general articles in the field. JCMID publishes articles that encompass basic research/clinical studies related to microbiology and infectious disease. The Journal aims to bridge and integrate the intellectual, methodological, and substantive diversity of medical scholarship and encourage a vigorous dialogue between medical scholars and practitioners.
Articles 63 Documents
Clinical and microbiological profile of patients with urinary tract infections at Mangusada Hospital, Badung Monika Febryanti Lebo Nuru; Marta Setiabudy; Anak Agung Gede Indraningrat
Journal of Clinical Microbiology and Infectious Diseases Vol. 6 No. 1 (2026): Available online : 1 June 2026
Publisher : Indonesian Society for Clinical Microbiology (Perhimpunan Dokter Spesialis Mikrobiologi Klinik Indonesia)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.51559/jcmid.v6i1.111

Abstract

Introduction: Urinary tract infections (UTIs) remain among the most common infectious diseases in healthcare settings and are increasingly complicated by antimicrobial resistance. This study aimed to describe the demographic characteristics, comorbidities, catheterisation history, and microbiological profile of UTI patients at Mangusada Regional Hospital. Methods: A descriptive cross-sectional study was conducted among 379 patients diagnosed with UTI from 2022 to 2024. Data were collected from medical records and microbiology laboratory reports. Variables included age, sex, comorbidities, urinary catheter use, and urine culture results. Data were analysed descriptively. Results: Urine culture samples consisted of 64 cases in 2022, 172 in 2023, and 143 in 2024. The highest average proportion of patients was found in the 0–5-year age group (28%), followed by those aged >65 years (11.6%). Sex distribution was nearly equal between males (50.1%) and females (49.9%). Benign prostatic enlargement was the most common comorbidity (13.4%), and most patients had no history of urinary catheter use (85.5%). Gram-negative bacteria predominated among culture-positive isolates (86%). Escherichia coli was the most frequently identified pathogen, with ESBL-producing strains accounting for approximately 50% of all E. coli isolates annually, followed by ESBL-producing Klebsiella pneumoniae. Conclusion: UTIs at Mangusada Regional Hospital were mainly associated with Gram-negative bacteria, particularly ESBL-producing E. coli and K. pneumoniae. These findings suggest limited effectiveness of third-generation cephalosporins as empirical therapy and highlight the need for ongoing antimicrobial surveillance and stewardship.
Antibacterial activity of aloe vera in inhibiting the growth of methicillin-resistant Staphylococcus aureus Ni Putu Ratih Permata Dewi Arya; Anak Agung Ayu Lila Paramasatiari; Ni Wayan Widhidewi; Marta Setiabudy
Journal of Clinical Microbiology and Infectious Diseases Vol. 6 No. 1 (2026): Available online : 1 June 2026
Publisher : Indonesian Society for Clinical Microbiology (Perhimpunan Dokter Spesialis Mikrobiologi Klinik Indonesia)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.51559/jcmid.v6i1.112

Abstract

Introduction: Antibiotic resistance is an increasing global health problem, particularly associated with Methicillin-Resistant Staphylococcus aureus (MRSA), which shows resistance to β-lactam antibiotics and can cause severe infections. This condition has encouraged the exploration of alternative antibacterial agents derived from natural sources. Aloe vera contains various bioactive compounds, such as saponins, flavonoids, tannins, and phenolic compounds, which potentially exhibit antibacterial activity. This study aimed to determine the effectiveness of Aloe vera extract in inhibiting the growth of MRSA. Methods: This experimental laboratory study employed a posttest-only control group design using the disk diffusion method on Mueller–Hinton agar. Aloe vera extract was tested at concentrations of 15μg/mL, 20μg/mL, 25μg/mL, and 50μg/mL. Vancomycin and 0.9% NaCl were used as positive and negative controls, respectively. Antibacterial activity was evaluated by measuring the diameter of inhibition zones. Data were analyzed descriptively. Result: The findings indicated that all concentrations of Aloe vera extract failed to produce inhibition zones against MRSA, with inhibition diameters of 0.00 mm. The positive control showed strong antibacterial activity, whereas the negative control exhibited no inhibitory effect. Conclusion: Aloe vera extract at concentrations of 15%, 20%, 25%, and 50% was not effective in inhibiting the growth of Methicillin-Resistant Staphylococcus aureus (MRSA) under in vitro conditions
Association between clinical outcomes of neonatal sepsis and microbial patterns and antibiotic resistance at Bali Mandara General Hospital, January–December 2024 Komang Nicko Juliasa; Luh Gde Ayu Pramitha Dewi; I Wayan Agus Gede Manik Saputra; Ida Ayu Sri Kusuma Dewi
Journal of Clinical Microbiology and Infectious Diseases Vol. 6 No. 1 (2026): Available online : 1 June 2026
Publisher : Indonesian Society for Clinical Microbiology (Perhimpunan Dokter Spesialis Mikrobiologi Klinik Indonesia)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.51559/jcmid.v6i1.113

Abstract

Background: Neonatal sepsis remains a major cause of morbidity and mortality globally, particularly in low-resource settings where antimicrobial resistance is increasing. This study aimed to identify microbial patterns, assess antibiotic resistance, and analyse their association with clinical outcomes among neonates treated for sepsis. Methods: A cross-sectional study was conducted on neonates aged 0–28 days with suspected sepsis and positive culture results admitted to the NICU and Perinatology Unit of Bali Mandara General Hospital from January to December 2024. Microbial isolates, antibiotic susceptibility, demographic characteristics, and clinical outcomes were analysed. Pearson’s Chi-square test was used to assess the association between Acinetobacter baumannii culture positivity and neonatal outcomes. Results: There were 75  samples There were 75  samples included in the final analysis. Gram-negative bacteria predominate, mainly carbapenem-resistant Acinetobacter baumannii (CRAB) (37.3%) and Klebsiella pneumoniae (24.0%). CRAB showed extensive antibiotic resistance, with residual susceptibility to amikacin and trimethoprim-sulfamethoxazole. Overall, 78.7% improved and 21.3% died. Mortality was higher in CRAB-positive neonates than in non-CRAB cases (35.8% vs. 12.8%; p = 0.019). Gestational age was significantly associated with outcomes (p = 0.006). Conclusion: Gram-negative bacteria, particularly A. baumannii and K. pneumoniae, were the leading causes of neonatal sepsis and demonstrated significant antimicrobial resistance. Although not statistically significant, A. baumannii infection showed a concerning trend toward higher mortality. Findings highlight the need for strengthened antimicrobial stewardship, updated empirical therapy, and enhanced infection-control practices in NICU settings.