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Andri Putra Kesmawan
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Perumahan Sidorejo, Jl. Sidorejo Gg. Sadewa No.D3, Sonopakis Kidul, Ngestiharjo, Kapanewon, Kasihan, Kabupaten Bantul, Daerah Istimewa Yogyakarta 55184
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Daerah istimewa yogyakarta
INDONESIA
Health & Medical Sciences
ISSN : -     EISSN : 30263867     DOI : https://doi.org.10.47134/phms
Core Subject : Health,
Pubmedia Health & Medical Sciences uses an online submission and peer review platform, which allows authors to track the progress of their manuscript and enables shorter processing times. Amidst the trend in attempting to constantly provide answers in problems or phenomena in our reality for a better health condition, Pubmedia Digital Series strive to publish a factual and applicable research result through the publication of journals from a wide arrange of field of studies such as in medicine, pharmacy, biology and the like. Focus and Scope Physiology Pharmacology Toxicology Genetics Neuroscience Tissue Engineering Regenerative Medicine Hematology Immunology Oncology Dentistry
Articles 201 Documents
Radiation Pneumonitis Following Thoracic Radiotherapy: A Systematic Review Sirait, Lionel
Health & Medical Sciences Vol. 3 No. 3 (2026): May
Publisher : Indonesian Journal Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.47134/phms.v3i3.611

Abstract

Radiation pneumonitis (RP) is a clinically significant and dose-limiting complication of thoracic radiotherapy, occurring despite modern delivery techniques. Its incidence and severity are influenced by a complex interplay of dosimetric, clinical, and patient-related factors, particularly in those receiving combined-modality therapies or with pre-existing pulmonary disease.Aim: To systematically summarize the incidence, risk factors, and predictive strategies for RP in patients undergoing thoracic radiotherapy, with emphasis on clinical, dosimetric, and emerging biological predictors. A PRISMA-guided literature search of PubMed/MEDLINE was conducted from inception to January 2026 using MeSH terms related to radiation pneumonitis and thoracic radiotherapy. Original research studies involving adult patients treated with thoracic radiotherapy and reporting RP-related outcomes were included. Owing to substantial heterogeneity across studies, findings were qualitatively synthesized rather than pooled quantitatively.  Twelve studies comprising approximately 1,298 patients were included. All studies demonstrated a strong association between lung dose-volume parameters and RP development. Maintaining lung V20 at approximately 20–23% was associated with lower symptomatic RP, with grade ≥2 incidence ranging from 5.5% to 13.3%. Patients with interstitial lung disease or idiopathic pulmonary fibrosis exhibited substantially higher risk, with RP ≥2 reported in up to 33% and severe RP in up to 42.1%. Emerging predictive models incorporating radiomics and biomarkers achieved AUC values up to 0.87. Lung dose exposure remains a key determinant of RP following thoracic radiotherapy. Limiting V20 to 20–23% may reduce toxicity, but individualized dose optimization, careful patient selection, and advanced risk stratification are essential — particularly in patients with underlying pulmonary disease or those receiving concurrent systemic therapies.
Gambaran Pola Luka Luar Korban Mati Usia Dewasa Akibat Penganiayaan di RS. Bhayangkara TK. II Sartika Asih Tahun 2022 – 2024 Afy, Sadad; Rusman, Andri; Handayani, Dewi
Health & Medical Sciences Vol. 3 No. 3 (2026): May
Publisher : Indonesian Journal Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.47134/phms.v3i3.613

Abstract

Assault is an intentional act that may result in injury or death and remains a significant global public health issue. This study aimed to describe the characteristics and patterns of external injuries among deceased adult victims of assault at Bhayangkara Hospital Level II Sartika Asih Bandung during 2022–2024. This research used a descriptive retrospective design based on secondary data from Visum et Repertum and medical records. A total of 100 samples meeting inclusion criteria (aged 18–59 years) were analyzed using univariate methods. The results showed that most victims were aged 18–44 years (81%) and predominantly male (79%). The majority of victims were employed (58%). Most cases underwent advanced forensic examination (PLPD) (94%). Regarding injury patterns, the most common number of external injuries was two injuries (49%), followed by three injuries (29%). Among cases with a single injury, stab wounds were the most frequent (35.29%), followed by contusions (29.41%). In cases with two injuries, the most common combination was contusion and abrasion (30.6%). In conclusion, fatal assault cases predominantly affect productive-age males and commonly involve multiple external injuries, with sharp-force trauma playing a significant role. These findings provide important forensic and public health insights for violence prevention strategies.
Stroke as a Global Health Issue: A Descriptive Analysis of the Theoretical Framework and Scientific Definitions Husni
Health & Medical Sciences Vol. 3 No. 3 (2026): May
Publisher : Indonesian Journal Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.47134/phms.v3i3.612

Abstract

This study aims to analyze stroke as a global health problem by examining its theoretical framework, scientific definitions, and underlying mechanisms through a comprehensive descriptive analysis. The research employs a qualitative approach using a descriptive method through a literature study. Data were collected through systematic literature searches and document analysis of credible academic sources, including peer reviewed journal articles and scientific publications discussing stroke epidemiology, risk factors, and pathophysiology. The collected literature was analyzed through qualitative procedures consisting of theme identification, data reduction, conceptual categorization, and inductive interpretation to develop a comprehensive understanding of the phenomenon. The results indicate that stroke remains one of the leading causes of mortality and long term disability worldwide, characterized by complex interactions between vascular dysfunction, metabolic risk factors, and molecular mechanisms such as neuroinflammation, oxidative stress, and neurovascular unit disruption. Hypertension and metabolic disorders were identified as the most significant modifiable risk factors contributing to the increasing global burden of stroke. Furthermore, advances in molecular neuroscience and emerging neurorehabilitation strategies provide new insights into prevention, diagnosis, and recovery processes. These findings highlight the importance of integrated approaches combining preventive healthcare, early detection, and multidisciplinary treatment strategies to address the global impact of stroke. In conclusion, this study contributes to strengthening the theoretical understanding of stroke as a multidimensional health issue and provides a conceptual foundation for future research and policy development in global health and cerebrovascular disease management.
Parenting Patterns and Diabetes Mellitus Prevention in Children A Descriptive Analysis of Literature Studies Andraini, Rus
Health & Medical Sciences Vol. 3 No. 3 (2026): May
Publisher : Indonesian Journal Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.47134/phms.v3i3.615

Abstract

This study aims to analyze the role of parenting patterns in preventing diabetes mellitus in children through a descriptive literature review approach. The increasing prevalence of childhood obesity and unhealthy lifestyles has raised concerns about the early risk of metabolic disorders, including diabetes mellitus, making family based prevention strategies increasingly important. This research employed a qualitative research design using a descriptive approach through a literature study. Data were collected through systematic searches of relevant academic sources, including peer reviewed journal articles, scientific publications, and other scholarly documents discussing parenting patterns, childhood obesity, and diabetes prevention. The collected data were analyzed using a thematic analysis process that involved identifying key themes, reducing and categorizing relevant information, and interpreting the findings inductively to obtain a comprehensive understanding of the relationship between parenting and childhood metabolic health. The results indicate that parenting patterns significantly influence children’s health behaviors, particularly in shaping dietary habits, physical activity, and lifestyle routines that affect the risk of obesity and metabolic disorders. Positive parental involvement, health literacy, and supportive family environments contribute to healthier behavioral patterns that reduce the likelihood of developing diabetes mellitus in childhood. These findings emphasize that effective prevention strategies should prioritize family centered health promotion, parental education, and collaborative efforts involving families, healthcare providers, schools, and communities. In conclusion, this study contributes to the understanding that parenting patterns are fundamental determinants in shaping children’s health behaviors and play an essential role in early prevention strategies aimed at reducing the risk of diabetes mellitus in children.
Identifikasi Persentase Kelengkapan Resep Rawat Inap dan Rawat Jalan di Instalasi Farmasi Rsud Dr. Zainal Umar Sidiki Kab. Gorontalo Utara Ratoe, Ridya Patricia Rivanda; Tuloli, Teti Sutriyati; Rasdianah, Nur
Health & Medical Sciences Vol. 3 No. 3 (2026): May
Publisher : Indonesian Journal Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.47134/phms.v3i3.619

Abstract

Kelengkapan resep merupakan salah satu indikator penting dalam pelayanan kefarmasian untuk menjamin keamanan dan efektivitas terapi serta mencegah medication error. Penelitian ini bertujuan untuk mengetahui persentase kelengkapan resep pasien rawat inap dan rawat jalan di Instalasi Farmasi RSUD dr. Zainal Umar Sadiki Kabupaten Gorontalo Utara berdasarkan aspek administratif, farmasetik, dan klinis. Penelitian ini menggunakan observasi deskriptif yang dilakukan secara retrospektif. Sampel penelitian sebanyak 377 resep yang diambil dengan teknik stratified random sampling. Data disajikan dalam bentuk persentase setelah analisis univariat. Hasil penelitian menunjukkan bahwa aspek farmasetik pada resep rawat inap dan rawat jalan telah lengkap 100%. Pada aspek administratif, komponen yang paling sering tidak lengkap adalah berat badan dan tinggi badan. Pada resep rawat inap, berat badan hanya tercantum 7,5% dan tinggi badan 6,7%, sedangkan pada resep rawat jalan berat badan tercantum 6,5% dan tinggi badan 2,4%. Pada aspek klinis, kelengkapan resep rawat jalan lebih tinggi dibandingkan rawat inap. Ketepatan indikasi pada resep rawat jalan sebesar 85,5%, sedangkan rawat inap 68,8%. Informasi alergi dan reaksi obat yang tidak dikehendaki (ROTD) merupakan komponen yang paling sering tidak lengkap, yaitu hanya 33,9% pada rawat jalan dan 11,1% pada rawat inap. Dapat disimpulkan bahwa aspek farmasetik telah memenuhi standar, namun aspek administratif dan klinis masih perlu ditingkan  untuk meningkatkan keselamatan pasien.
Integrasi Teleradiologi dalam Sistem Pelayanan Kesehatan: Dampak, Tantangan, dan Strategi Implementasi Berdasarkan Studi Literatur Mas'uul, Ali
Health & Medical Sciences Vol. 3 No. 3 (2026): May
Publisher : Indonesian Journal Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.47134/phms.v3i3.628

Abstract

Penelitian ini bertujuan untuk menganalisis integrasi teleradiologi dalam sistem pelayanan kesehatan serta mengidentifikasi manfaat, tantangan, dan implikasinya terhadap peningkatan kualitas layanan. Metode yang digunakan adalah penelitian kualitatif dengan pendekatan deskriptif melalui studi pustaka, dengan teknik pengumpulan data berupa penelusuran literatur, analisis dokumen, dan kajian teoritis terhadap berbagai artikel ilmiah, laporan penelitian, dan dokumen relevan. Analisis data dilakukan secara induktif melalui tahapan identifikasi tema, reduksi data, kategorisasi konsep, dan penarikan kesimpulan. Hasil penelitian menunjukkan bahwa teleradiologi berperan penting dalam meningkatkan akses layanan diagnostik, mempercepat waktu diagnosis, serta meningkatkan efisiensi alur kerja radiologi, terutama di wilayah dengan keterbatasan tenaga medis. Namun, implementasinya masih menghadapi berbagai kendala, seperti keterbatasan infrastruktur, kurangnya integrasi data, isu keamanan informasi, serta kesiapan organisasi dan sumber daya manusia. Temuan ini menegaskan bahwa keberhasilan integrasi teleradiologi sangat bergantung pada kesiapan teknologi, regulasi, dan manajemen sistem yang terintegrasi. Secara keseluruhan, penelitian ini memberikan kontribusi dalam memperkuat pemahaman mengenai peran teleradiologi sebagai bagian dari transformasi digital pelayanan kesehatan serta memberikan dasar bagi pengembangan kebijakan dan praktik yang lebih efektif di masa depan.
Maternal-Fetal Attachment (MFA) in the Context of Pregnancy Adaptation: A Literature Review of Internal and External Factors Affecting Mothers Aniroh, Umi; Mawardika, Tina
Health & Medical Sciences Vol. 3 No. 3 (2026): May
Publisher : Indonesian Journal Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.47134/phms.v3i3.629

Abstract

This study aims to analyze Maternal Fetal Attachment (MFA) within the context of pregnancy adaptation by examining the influence of internal and external maternal factors through a qualitative descriptive literature approach. The research employs a library study method using secondary data sources, including peer reviewed journal articles and relevant academic documents, collected through systematic literature search and analyzed using thematic analysis, data reduction, categorization, and inductive interpretation. The findings reveal that MFA is a multidimensional construct influenced by internal factors such as maternal mental health, particularly depression and anxiety, as well as positive psychological states, and external factors including social and family support. Pregnancy adaptation emerges as a key mediating process that connects these factors to the quality of maternal fetal bonding. The study also highlights that strong MFA contributes to positive infant developmental outcomes, especially in emotional regulation and adaptive behavior. These findings imply that maternal well being and supportive social environments are essential components in strengthening prenatal attachment. In conclusion, this study contributes to the theoretical understanding of MFA as a biopsychosocial process and provides practical insights for integrating mental health screening and family centered interventions in antenatal care to improve maternal and child health outcomes.
The Therapeutic Potential of Borassus flabellifer in Oral Mucosal Regeneration and Repair: A Review Ramaniasari, Sheryn; Cindy Hendrawan; Hasudungan, Dian Samuel; Hidayati, Nurul
Health & Medical Sciences Vol. 3 No. 3 (2026): May
Publisher : Indonesian Journal Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.47134/phms.v3i3.630

Abstract

The oral mucosa is a vital component of the human body, forming the moist lining of the oral cavity and acting as the first barrier against physical, chemical, and microbial insults. Oral mucosal injuries are among the most common conditions in dental practice and may result from mechanical trauma, infections, systemic diseases, or iatrogenic factors. In physically active individuals and athletes, the risk of orofacial injury is significantly higher due to repeated exposure to impact and mechanical stress. Borassus flabellifer, a tropical plant widely used in traditional medicine, has gained attention due to its rich phytochemical content, including flavonoids, polyphenols, and saponins. To evaluate the regenerative potential of Borassus flabellifer as a therapeutic agent for oral mucosal wound healing based on available scientific evidence. A structured literature search was conducted across PubMed, ScienceDirect, and Google Scholar using Boolean search strategies based on the PICO framework. Studies published between 2016 and 2026 were screened according to predefined inclusion criteria. Results: A total of 5 eligible studies were identified and included in this review. The findings consistently demonstrated that Borassus flabellifer exhibits anti-inflammatory and antioxidant properties, which are key mechanisms in promoting wound healing. These studies reported enhanced tissue regeneration, reduced inflammation, and improved healing outcomes associated with its phytochemical constituents. Borassus flabellifer shows promising potential as a natural therapeutic agent for oral mucosal wound healing. Its bioactive compounds support its development as a topical treatment; however, further clinical studies are needed to confirm its efficacy and safety
Efficacy and Safety of GLP-1 Receptor Agonists as Adjuvant Pharmacotherapy After Bariatric Surgery: A Narrative Review Sinaga, Natanael; Sirait, Lionel
Health & Medical Sciences Vol. 3 No. 3 (2026): May
Publisher : Indonesian Journal Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.47134/phms.v3i3.631

Abstract

Bariatric surgery remains the most effective long-term intervention for severe obesity, yet many patients experience inadequate weight loss or post-operative weight regain. GLP-1 receptor agonists (GLP-1 RAs) have emerged as promising adjuvant options through complementary mechanisms of appetite suppression and glycemic regulation.Aim: To evaluate the efficacy and safety of GLP-1 RAs as adjuvant pharmacotherapy in adult post-bariatric surgery patients. Methods, A systematic PubMed/MEDLINE search was conducted from January 2015 to January 2026. Eligible studies included adult post-bariatric patients receiving any GLP-1 RA with reported weight, glycemic, or safety outcomes. Case reports, animal studies, and review articles were excluded. Results, Eleven studies comprising 873 patients were included. GLP-1 RAs consistently demonstrated clinically meaningful weight reduction across all agents, with total body weight loss ranging from 5% to over 15% depending on agent, dose, and follow-up duration. Semaglutide demonstrated superior weight loss over liraglutide in head-to-head comparisons, while tirzepatide showed the greatest overall weight reduction. Glycemic improvements were most pronounced in patients with persistent or recurrent type 2 diabetes. Adverse events were predominantly gastrointestinal and mild-to-moderate in severity. Conclusion, GLP-1 RAs are effective and well-tolerated adjuvant therapies following bariatric surgery. Tirzepatide and semaglutide appear to offer greater weight loss benefit compared to liraglutide. Individualized agent selection based on patient characteristics and tolerability is recommended. Prospective randomized trials with standardized outcome reporting are needed to establish definitive clinical guidelines.
Prevalensi dan Faktor Risiko Neuropati Diabetik Pada Pasien Diabetes Melitus Tipe 2 Dengan Durasi Penyakit Lebih Dari Lima Tahun di Klinik Diabetes Melitus RSUD Prof. Dr. Margono Soekarjo Purwokerto Ahmad Kahfi Lutfi Jamaludin; Pugud Samodro; Yosefin Ratnaningtyas
Health & Medical Sciences Vol. 3 No. 3 (2026): May
Publisher : Indonesian Journal Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.47134/phms.v3i3.635

Abstract

Diabetes Melitus Tipe 2 (DMT2) adalah penyakit kronis yang sering memicu kerusakan saraf perifer (neuropati diabetik). Kondisi ini menyebabkan nyeri hingga penurunan kualitas hidup, terutama pada pasien yang sudah mengidap diabetes lebih dari 5 tahun. Penelitian ini bertujuan untuk mengetahui angka kejadian (prevalensi) serta faktor risiko neuropati diabetik di RSUD Prof. Dr. Margono Soekarjo. Metode: Studi ini menggunakan desain observasional analitik dengan pendekatan potong lintang (cross-sectional). Sebanyak 141 pasien DMT2 dengan riwayat penyakit di atas 5 tahun dilibatkan sebagai sampel. Data kemudian dianalisis menggunakan uji statistik bivariat (chi-square) dan multivariat (regresi logistik berganda). Angka kejadian neuropati diabetik ditemukan sangat tinggi, yakni mencapai 80% dari total pasien. Secara statistik, hipertensi terbukti memiliki hubungan yang signifikan dengan kejadian kerusakan saraf ini (p < 0,05). Sebaliknya, faktor status gizi, dislipidemia, kebiasaan merokok, dan kontrol gula darah tidak menunjukkan hubungan yang bermakna (p > 0,05). Berdasarkan uji akhir multivariat, hipertensi diidentifikasi sebagai faktor risiko yang paling dominan memengaruhi munculnya neuropati diabetik. Pasien DMT2 yang sudah sakit lebih dari 5 tahun memiliki risiko neuropati diabetik yang sangat tinggi, di mana tekanan darah tinggi (hipertensi) bertindak sebagai faktor pemicu utamanya.