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INDONESIA
Health & Medical Sciences
Published by Indonesian Journal Publisher
ISSN : -     EISSN : 30263867     DOI : https://doi.org.10.47134/phms
Core Subject : Health,
Dentistry Health Professions Medicine & Pharmacology Nursing Public Health
Pubmedia Health & Medical Sciences uses an online submission and peer review platform, which allows authors to track the progress of their manuscript and enables shorter processing times. Amidst the trend in attempting to constantly provide answers in problems or phenomena in our reality for a better health condition, Pubmedia Digital Series strive to publish a factual and applicable research result through the publication of journals from a wide arrange of field of studies such as in medicine, pharmacy, biology and the like. Focus and Scope Physiology Pharmacology Toxicology Genetics Neuroscience Tissue Engineering Regenerative Medicine Hematology Immunology Oncology Dentistry
Arjuna Subject : Kedokteran - Kedokteran (Lain-Lain)
Articles 151 Documents
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Self-Awareness and Quality of Life in Menopausal Women: A Concept Analysis Noorma, Nilam; Hapsari, Ririn; Aisah, Siti; Vranada, Aric
Health & Medical Sciences Vol. 3 No. 1 (2025): November
Publisher : Indonesian Journal Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.47134/phms.v3i1.553

Abstract

This study aims to clarify the concept of self-awareness in menopausal women and examine its relationship with quality of life (QoL) using Walker and Avant’s concept analysis framework. The analysis included articles published between 2021 and 2025, retrieved from databases such as Google Scholar, ProQuest, PubMed, CINAHL, and Science Direct, using keywords “menopause,” “self-awareness,” “quality of life,” and “concept analysis.” The findings reveal that self-awareness in menopausal women comprises interoceptive awareness, cognitive insight, emotional recognition and regulation, health literacy, and adaptive behavioral responses. Antecedents of self-awareness include health literacy, access to information, emotional support, mindfulness experience, and motivation for self-care. Its consequences involve improved symptom management, adaptive coping, reduced anxiety and depression, and enhanced physical, psychosocial, and sexual QoL. Empirical referents identified include MENQOL, MRS, MAAS, MAIA, symptom diaries, and outcomes of mindfulness or self-awareness interventions. The study concludes that self-awareness is a multidimensional construct essential for improving the QoL of menopausal women. Clarifying this concept establishes a theoretical foundation for developing targeted nursing interventions, standardized measurement tools, and future research exploring mechanisms linking self-awareness to QoL.
Descriptive Study on the Application of Early Warning Systems in Emergency Nursing Practice Alfiani, Desi
Health & Medical Sciences Vol. 3 No. 1 (2025): November
Publisher : Indonesian Journal Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.47134/phms.v3i1.555

Abstract

This study aims to describe and analyze the implementation of the Early Warning System (EWS) in emergency nursing practice as a mechanism to enhance patient safety and clinical responsiveness. Employing a qualitative descriptive approach through a literature-based study, this research integrates data from peer-reviewed journals, academic reports, and relevant clinical documents published between 2015 and 2025. Data were collected through systematic literature review and analyzed inductively using thematic identification, data reduction, conceptual categorization, and interpretation to obtain a comprehensive understanding of EWS application in clinical settings. The findings reveal that EWS contributes significantly to early detection of patient deterioration, reduction of unplanned ICU admissions and cardiac arrests, and improvement in nurses’ clinical judgment and interprofessional collaboration. However, challenges such as limited compliance, alert fatigue, and contextual variations in system effectiveness remain obstacles to optimal implementation. The study highlights the importance of continuous education, system customization, and institutional support to ensure sustainable integration of EWS in emergency care. The results contribute to the theoretical enrichment of patient safety frameworks and offer practical guidance for developing adaptive, evidence-based nursing systems. In conclusion, the application of EWS represents a vital step toward advancing proactive, data-informed nursing practices that strengthen patient safety and professional competence in emergency healthcare environments.
Pathophysiology of Atherosclerosis Formation in Autoimmune Diseases: Rheumatoid Arthritis, Systemic Lupus Erythematosus, Primary Sjögren’s Syndrome, and Antiphospholipid Syndrome Pranaja, Dwi Aryasatya; Anita Liliana Susanti; Andri A. Rusman
Health & Medical Sciences Vol. 3 No. 1 (2025): November
Publisher : Indonesian Journal Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.47134/phms.v3i1.556

Abstract

This study aimed to systematically examine the autoimmune mechanisms contributing to atherosclerosis development in patients with Rheumatoid Arthritis, Systemic Lupus Erythematosus, Sjögren’s syndrome, and Antiphospholipid Syndrome. The focus was on identifying immunological pathways, inflammatory mediators, and vascular changes that accelerate atherosclerosis in these autoimmune conditions. A systematic scoping review was conducted following established scoping review guidelines. Peer-reviewed studies on immune-mediated processes, endothelial dysfunction, lipid changes, or cardiovascular outcomes in autoimmune diseases were sourced from PubMed, Scopus, and Web of Science, screened via electronic searches and predefined inclusion criteria. Data extraction focused on immune cell involvement, cytokine profiles, mechanisms of vascular injury, and indicators of atherosclerotic progression.The results demonstrated that chronic systemic inflammation is a central mechanism driving accelerated atherosclerosis in autoimmune diseases. Activated immune cells, particularly monocytes, macrophages, and T lymphocytes, were consistently reported to infiltrate the vascular endothelium, promoting endothelial dysfunction and intimal thickening. Pro-inflammatory cytokines such as tumor necrosis factor-alpha and interferon-gamma were frequently associated with increased expression of adhesion molecules, oxidative stress, and foam cell formation. Altered lipid metabolism, including increased levels of oxidized low-density lipoprotein, further contributed to plaque development. In Antiphospholipid Syndrome, autoantibody-mediated endothelial injury and thrombogenic processes were prominent, while immune complex deposition and complement activation were key contributors in Systemic Lupus Erythematosus. Overall, the findings indicate that immune dysregulation and persistent inflammation substantially increase cardiovascular risk in patients with autoimmune diseases, underscoring the need for targeted anti-inflammatory and immunomodulatory strategies to reduce atherosclerotic burden
Differences in Glutathione Peroxidase (GPx) Levels Before and After Pulmonary Tuberculosis Treatment Putri, Ersty Marthalia; Anita Liliana Susanti; Deasy Wirasiti
Health & Medical Sciences Vol. 3 No. 1 (2025): November
Publisher : Indonesian Journal Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.47134/phms.v3i1.557

Abstract

This study aimed to review changes in glutathione peroxidase or GPx levels or activity before and after pulmonary tuberculosis treatment. A systematic scoping review was conducted on articles published between 2016 and 2025 retrieved from Google Scholar, ScienceDirect, and PubMed. Article selection followed PRISMA guidelines and applied eligibility criteria based on the PICO framework. Six studies met the inclusion criteria and were included in the analysis. All reviewed studies reported changes in GPx levels or activity after tuberculosis treatment, with most showing an increase in GPx activity following anti-tuberculosis therapy. Several studies also reported that adjunct antioxidant interventions, such as N-acetylcysteine, contributed to enhanced glutathione system function and increased GPx activity compared to standard therapy alone. The observed increase in GPx activity was associated with reduced oxidative stress and improved redox balance during treatment. These findings indicate that GPx has potential as a biomarker for monitoring treatment response in pulmonary tuberculosis. However, variations in study design, sample size, and measurement methods were identified across the included studies. Further well-designed clinical studies with standardized GPx assessment protocols are needed to confirm its clinical utility and to clarify the role of antioxidant supplementation in supporting tuberculosis treatment outcomes.
Profil Metabolom pada Infeksi Histoplasmosis: Tinjauan Literaturc Kanza, Kayla; Susanti, Anita; Choerunisa, Towifah
Health & Medical Sciences Vol. 3 No. 1 (2025): November
Publisher : Indonesian Journal Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.47134/phms.v3i1.558

Abstract

Penelitian ini bertujuan untuk mengkaji peran pendekatan metabolomik dalam memahami patogenesis histoplasmosis serta potensinya dalam pengembangan biomarker dan target terapi berbasis metabolisme. Metode penelitian dilakukan melalui tinjauan literatur sistematis terhadap enam studi metabolomik eksperimental dan klinis yang membahas perubahan profil metabolit selama infeksi Histoplasma capsulatum. Hasil kajian menunjukkan bahwa Histoplasma capsulatum memiliki kemampuan adaptasi metabolik yang signifikan, ditandai dengan peningkatan kadar mannitol, derivat asam amino aromatik, metabolit branched-chain amino acid, serta lipid struktural. Perubahan metabolik tersebut mencerminkan dominasi respirasi mitokondria, aktivasi jalur glukoneogenesis, serta keterlibatan siklus asam sitrat (TCA), jalur glyoxylate, dan metabolisme lipid dalam mendukung kelangsungan hidup patogen selama proses infeksi. Pada sisi inang, infeksi histoplasmosis berkaitan dengan gangguan metabolisme energi yang ditunjukkan oleh perubahan metabolit TCA, yang berperan dalam modulasi respons imun dan peningkatan stres oksidatif. Interaksi metabolik antara patogen dan inang tersebut menunjukkan adanya mekanisme adaptif yang kompleks selama perjalanan penyakit. Simpulan dari penelitian ini menegaskan bahwa pendekatan metabolomik memberikan pemahaman yang komprehensif mengenai mekanisme patogenesis histoplasmosis serta memiliki potensi besar dalam pengembangan biomarker diagnostik dan strategi terapi yang lebih spesifik dan tepat sasaran.
Assessment of Nurses' Performance in Caring for Cancer Patients in Kirkuk City: a Cross Sectional Study Muhammed, Hamdiya; Salih , Yousif
Health & Medical Sciences Vol. 3 No. 1 (2025): November
Publisher : Indonesian Journal Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.47134/phms.v3i1.559

Abstract

Cancer is considered one of the major issues in the twenty-first century. It's one of the leading causes of death and a barrier to life expectancy, globally. Its burden expected to increase worldwide from 2020 and throughout the first half of the 21st century. Nurses as one of the medical team are considered at the frontline in mitigating this increasing, through their contributions in patients care with their diversity of care roles and responsibilities in cancer care. This study aimed to assess oncology nurses level of performance in cancer care in Kirkuk City. Methods, a descriptive (cross sectional) design conducted at Oncology and Hematology Center in Kirkuk City, Iraq. An observational checklist used to collect data of 81 nurse in the time line between February 15th, 2025 to March 27th,2025. Results, nurses showed an overall weak adherence to cancer care protocols in general(PGMS=24.28%), where nurses scored low levels in both the " Supportive and psychological nursing care" and "Nursing care throughout chemotherapy treatments" with a Percentile Grand/Global Mean of Score (PGMS) of 8.80%,and 8.82% respectively; while they showed a moderate level in regard to "Nursing care prior to handling chemotherapeutic agents", (PGMS=56.02%). No relationship accounted between Nurses' performance level and the studied respondent's socio-demographics(age, educational background, and years of experience), since no significant a contingency coefficients are accounted at P>0.05, except in regard of gender variable (CC = 0.249) at the value of P < 0.05,showing a better advantage for male over females. Conclusion: The findings indicates a weak adherence to the protocols regarding cancer patient care, indicating the need for further focus on the provision of continuous trainings. Furthermore, the findings of the study allow us to make the assumption that nurses' age , educational qualification, and experience doesn't necessarily have to play a significant role in the evaluation of nurse competence and quality of nursing care provided in all of the environments.
Faktor-Faktor Risiko pada Pasien Kanker Paru dan Skrining di Indonesia Amalia, Salsabila; Windarti, Indri; Irawati, Nur; Infianto, Andreas
Health & Medical Sciences Vol. 3 No. 2 (2026): February
Publisher : Indonesian Journal Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.47134/phms.v3i2.560

Abstract

Kanker paru merupakan penyebab utama kematian akibat kanker di Indonesia dan masih menjadi tantangan kesehatan masyarakat yang signifikan. Tingginya angka kejadian dan mortalitas kanker paru disebabkan oleh paparan faktor risiko yang kompleks serta keterlambatan diagnosis. Faktor risiko utama meliputi merokok aktif dan pasif, paparan polusi udara, zat karsinogen lingkungan dan pekerjaan, penggunaan bahan bakar biomassa, riwayat penyakit paru kronik, serta faktor genetik. Strategi skrining berbasis risiko menggunakan Low-Dose Computed Tomography (LDCT) telah terbukti secara global mampu menurunkan mortalitas kanker paru dan mulai diadopsi di Indonesia melalui konsensus profesional dan kebijakan nasional. Penelitian ini bertujuan untuk menganalisis faktor risiko kanker paru serta mengevaluasi implementasi strategi skrining nasional di Indonesia berdasarkan bukti ilmiah lima tahun terakhir (2020–2025). Metode yang digunakan adalah tinjauan pustaka sistematis terhadap jurnal internasional, nasional, dan dokumen kebijakan. Jurnal ini meninjau literatur terbaru (2020–2025) mengenai faktor risiko dominan dan efektivitas skrining menggunakan Low-Dose Computed Tomography (LDCT) di Indonesia. Hasil analisis menunjukkan bahwa meskipun merokok tetap menjadi faktor utama, faktor non-tradisional seperti pajanan biomassa dan polusi udara urban berkontribusi pada peningkatan kasus pada non-perokok. Implementasi skrining nasional menghadapi tantangan aksesibilitas alat, namun transformasi kesehatan digital memberikan harapan baru bagi deteksi dini.
Pengaruh Pemberian Ekstrak Daun Salam (Eugenia Polyantha) Terhadap Kadar Asam Urat pada Pasien Prolanis di Klinik Iman Ayundari, Palupi; Rahman, Shahrul
Health & Medical Sciences Vol. 3 No. 2 (2026): February
Publisher : Indonesian Journal Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.47134/phms.v3i2.561

Abstract

The objective of this study was to examine the effect of bay leaf extract on uric acid levels in patients with hyperuricemia. The study used a quantitative approach with a non equivalent control group experimental design. Participants were divided into an experimental group and a control group. The experimental group received bay leaf extract, while the control group received no intervention. Uric acid levels were measured before and after the intervention. Data analysis used the Paired Sample T-Test to compare uric acid levels before and after treatment in the experimental group. The results showed a significant reduction in uric acid levels after administration of bay leaf extract. The p value was 0.002, which is lower than 0.05, indicating a statistically significant difference. These findings demonstrate that bay leaf extract has a significant effect on reducing blood uric acid levels in patients with hyperuricemia at Klinik Iman. The study provides empirical evidence supporting the potential use of bay leaf extract as an alternative herbal therapy for managing hyperuricemia.
The Relationship Between Hamstring Tightness and Lumbar Hyperlordosis and Trunk Flexibility in Students at Muhammadiyah University Surabaya Siwi, Ken; Romadhona, Nurul; Kirana, Anisha
Health & Medical Sciences Vol. 3 No. 2 (2026): February
Publisher : Indonesian Journal Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.47134/phms.v3i2.562

Abstract

This study aims to investigate the relationship between hamstring tightness and lumbar hyperlordosis and trunk flexibility in students at Muhammadiyah University Surabaya. The study used a quantitative approach with a cross-sectional observational study design involving 30 students with hamstring tightness disorders. Hamstring tightness was measured using the straight leg raise test, the lumbar lordosis angle was measured with a flexicurve, and trunk flexibility was measured using the fingertip to floor test. Data analysis was performed using Pearson Product Moment correlation test with a significance level of p < 0.05. The results showed a significant correlation between hamstring tightness and trunk flexibility with a p-value of 0.00 and a very strong correlation coefficient (R = 0.984), while lumbar hyperlordosis data did not show a significant correlation with trunk flexibility or hamstring tightness. The conclusion of this study confirms that hamstring shortening has a very strong relationship with limited trunk flexibility, but is not directly related to changes in the lumbar lordosis angle. These findings highlight the importance of physiotherapy interventions that focus on increasing hamstring flexibility as a preventive and functional strategy for students with high sedentary activities.
The Role of Nurses in Managing Self-Care for Diabetes Mellitus Patients in Surgical Medical Services: A Literature Review Pangandaheng, Tommy
Health & Medical Sciences Vol. 3 No. 2 (2026): February
Publisher : Indonesian Journal Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.47134/phms.v3i2.563

Abstract

This study aims to explore the role of nurses in managing self-care among patients with diabetes mellitus in medical-surgical services through a comprehensive literature review. Using a qualitative descriptive design, the research employed a library-based approach that analyzed 22 peer-reviewed articles published between 2019 and 2025. Data were collected through systematic literature tracing, document analysis, and thematic synthesis to identify recurring patterns in nursing interventions related to diabetes self-care management. The analysis revealed five dominant thematic areas: (1) diabetes self-management education (DSME), (2) psychosocial and spiritual support, (3) wound and foot care management, (4) family involvement in self-care, and (5) integration of health information technology. The findings demonstrate that nurses play a central role as educators, motivators, and care coordinators in improving patient self-efficacy, treatment adherence, and glycemic control. Moreover, the integration of family support and digital health interventions enhances continuity of care and patient empowerment. These results reinforce the relevance of Orem’s Self-Care Deficit Nursing Theory and Bandura’s Self-Efficacy Theory in nursing practice while providing evidence for the holistic and transformative contributions of nurses in chronic disease management. The study concludes that advancing interprofessional collaboration, digital health integration, and culturally sensitive approaches are essential to optimizing diabetes self-care outcomes and enhancing nursing professionalism.

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