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Ad-dawaa: Journal Of Pharmacy
Published by Sekolah Tinggi Ilmu Kesehatan Muhammadiyah Ciamis
ISSN : -     EISSN : 29874157     DOI : https://doi.org/10.52221/dwj.v1i2
Core Subject : Health, Science,
Chemistry Medicine & Pharmacology
Ad-dawaa Journal Of Pharmacy is an official journal published by LPPM STIKes Muhammdiyah Ciamis which can be accessed and downloaded online through an open access journal. Ad-dawaa Journal Of Pharmacy is published two times a year in the form of research articles in the pharmaceutical field with the following scientific areas: Clinical Pharmacy Pharmacology Biotechnology Of Pharmacy Community Pharmacy Pharmaceutical chemistry Pharmacognosy Management pharmacy
Arjuna Subject : Pharmacology, Toxicology and Pharmaceutics - Ilmu Farmasi
Articles 33 Documents
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Activity Test of Combination of Binahong Leaf Extract (Anredera Cordifolia) and Lemongrass Extract (Cymbopogon citratus) as Antifungal Againt Pityrosporum ovale Wahlanto, Panji; Ramadhan, M. Fadil
Ad-Dawaa : Journal of Pharmacy Vol. 1 No. 1 (2023): Ad-Dawaa: Journal of Pharmacy (May 2023)
Publisher : LPPM STIKes Muhammadiyah Ciamis

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.52221/dwj.v1i1.221

Abstract

Pityrosporum ovale is a microorganism thought to be the main cause of dandruff. Binahong and lemongrass are herbal plants that can cure various diseases. Based on usage empirical leaf binahong and lemongrass kitchen nutritious for remove dandruff, hair loss, diabetes mellitus, anti- cancer and treatment on infection skin caused by bacteria nor mushrooms. Binahong leaf extract and extract lemongrass contain metabolites secondary wrong only flavonoids. Flavonoids are effective as antimicrobials. Destination from study this The purpose of this study was to determine the antifungal activity of the combination of binahong leaf extract (Anredera cordifolia) and lemongrass extract (Cymbopogon citratus) against Pityrosporum ovale . This study used 5 test groups, which consisted of a combination group of binahong leaf extract and lemongrass F1 = concentration 50%:50%, F2 = concentration 37,5%:12,5%, F3 = concentration 25%:25% and F4 = concentration 12,5%:37,5%, and the control group was positive (ketoconazole 2%) and negative ( aquadest), with 3 repetitions. The materials used in this study were binahong leaf simplicia and kitchen lemongrass simplicia macerated using 70% ethanol solvent, resulting in a thick extract which was then tested for antifungal activity against Pityrosporum ovale by the method diffusion paper disc on Sabouraud Dextrose Agar medium . The parameter observed was the diameter of the growth inhibition zone of the fungus Pityrosporum ovale . Analysis using ANOVA (Analysis of Variance). The results of this study were binahong leaf extract and kitchen lemongrass extract positive containing flavonoid compounds. The combination of binahong leaf extract and citronella extract has the ability to inhibit the growth of the fungus Pityrosporum ovale with visible inhibition zones formed. The most effective concentration to inhibit the growth of the fungus Pityrosporum ovale was at a concentration of F1 = 50%:50% of 17.40 mm with a strong category.
Identification of Formalin in Food Sold in Ciamis by Thin Layer Chromatography Permana, Indra; Irmasyanti, Imas
Ad-Dawaa : Journal of Pharmacy Vol. 1 No. 1 (2023): Ad-Dawaa: Journal of Pharmacy (May 2023)
Publisher : LPPM STIKes Muhammadiyah Ciamis

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.52221/dwj.v1i1.226

Abstract

Formalin is a non-food preservative that is now widely used to preserve food. Formaldehyde is the trade name of formalin consisting of a mixture of formaldehyde, methanol and water. Formaldehyde on the market has various formaldehyde levels, between 20% - 40%. Formalin is a preservative that is prohibited for use in food products. However, there are traders who use formaldehyde in food products. The purpose of this study was to identify formaldehyde in food sold in Ciamis District. This study is a description of the phenomena found in the field, namely the presence of foods containing formalin. The method used was KmnO4 reagent and Thin Layer Chromatography. The results showed that of the 5 food samples tested using KmnO4, positive results were obtained for tofu, salted fish, fresh fish, and chicken meat which were marked by a loss of purple color during testing. With the Thin Layer Chromatography method, the Rf value of tofu was 0.60, salted fish was 0.61, fresh fish was 0.61 and chicken meat was 0.62
Formulation and Evaluation of Peel-Off Gel Mask with Tomato Fruit Extract Using PVA Base Rahmi, Ai; Yusuf, Anna L
Ad-Dawaa : Journal of Pharmacy Vol. 2 No. 1 (2024): Ad-Dawaa: Journal of Pharmacy (May 2024)
Publisher : LPPM STIKes Muhammadiyah Ciamis

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.52221/dwj.v2i1.731

Abstract

Tomatoes have been widely used in society as a homemade mask by mashing them until smooth and then applying them to the face. Tomatoes have health and beauty benefits because they have high nutritional content such as antioxidants lycopene, vitamin C, potassium, folate and vitamin A. Using tomatoes as a mask has benefits for the skin because they have antioxidant activity so they can provide a brightening effect and can prevent aging. Peel-off gel masks are one of the masks that are practical to use, because after drying the mask can be removed immediately without rinsing. Peel-off gel masks are made with a Polyvinyl Alcohol (PVA) base as a gelling agent that has the ability to form a film layer so that it is easy to peel off after drying. Evaluation of the peel-off gel mask preparation consists of organoleptic tests, viscosity tests, pH tests, spreadability tests and drying time tests. From the results of organoleptic observations, the resulting preparation is a thick preparation with a distinctive tomato odor and has a brick red color. The evaluation results of the viscosity test, pH test, spreadability test and drying time test showed that the peel-off gel mask preparation met the requirements.
Evaluation Of Drug Prescription Base On Hospital Formularium In The Outpatient Installation In A Hospital Tasikmalaya Region Ruhaniyyah, Ai Syifa
Ad-Dawaa : Journal of Pharmacy Vol. 2 No. 2 (2024): Ad-Dawaa: Journal of Pharmacy (November 2024)
Publisher : LPPM STIKes Muhammadiyah Ciamis

Show Abstract | Download Original | Original Source | Check in Google Scholar

Abstract

Hospital Formulary is a document that regulates pharmaceutical services in a Hospital, containing a list of drugs and drug use policies in the Hospital as well as instructions for their use. The Hospital Formulary has a very important role in the use of drugs for patients in the Hospital, in addition to functioning to ensure the quality and accuracy of drug use. The purpose of this study was to evaluate the suitability of prescription writing in the Outpatient Installation based on the hospital formulary in a hospital in the Tasikmalaya area. The method used in this study is a non-experimental type of research that is descriptive in nature with data collected retrospectively. The analysis period was carried out for one year from January to December. The results of the study showed that the percentage of prescription suitability by calculating the prescribed drug items was in the range of 89% -95%. The highest percentage of drug item suitability was achieved in September and November, which was 95%. The average percentage of drug item suitability during January-December was 92%. From the results of this study, it can be concluded that prescriptions in a Hospital in the Tasikmalaya Area show compliance with the Hospital Formulary
The Influence of the Level of Public Knowledge on the Rationality of Self-Medicine for Diarrhea in Sukaratu Tasikmalaya Arman, Siti Alisa; Wahlanto, Panji
Ad-Dawaa : Journal of Pharmacy Vol. 2 No. 2 (2024): Ad-Dawaa: Journal of Pharmacy (November 2024)
Publisher : LPPM STIKes Muhammadiyah Ciamis

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.52221/dwj.v2i2.733

Abstract

Self-medication is one of the choices of Indonesian people in treating their illnesses, one of which is treating diarrhea. Diarrhea is a symptom of abnormality in frequent bowel movements, with liquid stool consistency. The frequency of bowel movements is said to be abnormal if it is more than three times a day. The purpose of this study was to determine the relationship between the level of knowledge and the rationality of self-medication for diarrhea in Sukaratu Tasikmalaya. This study is an observational study, with a research design with a cross-sectional approach. The number of research samples was 43 people from Batu Bulu Village, Linggajati Village, Sukaratu District, Tasikmalaya Regency. The sampling technique was carried out using purposive sampling. Research data were obtained from questionnaires. Analysis of research data using the Pearson Correlation test, to determine the relationship between the level of community knowledge and the rationality of self-medication for diarrhea. The results showed that out of 43 respondents, 36 respondents had a level of knowledge in the good category, 2 respondents were sufficient and 5 respondents had poor knowledge. The distribution of rationality for self-medication for diarrhea showed that 24 respondents had the right rationality and 19 respondents had the wrong rationality.
Isolation and Identification of Chlorophyll from Pandan Leaf Extract Using Column Chromatography Asmarani, Bening Putri
Ad-Dawaa : Journal of Pharmacy Vol. 2 No. 2 (2024): Ad-Dawaa: Journal of Pharmacy (November 2024)
Publisher : LPPM STIKes Muhammadiyah Ciamis

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.52221/dwj.v2i2.734

Abstract

Pandan is a plant whose leaves are often used by some people as an additional ingredient in food, especially as a natural dye and aromatizer. Pandan has green leaves due to the presence of chlorophyll in the leaves. Chlorophyll has benefits as an anti-cancer and is useful in cancer treatment therapy. Because pheophytin is able to activate radical compounds that are harmful to cells, this therapy is called photodynamic therapy. The purpose of this study was to isolate and identify chlorophyll in pandan leaf extract by column chromatography method using a combination of chloroform, ethyl acetate and ethanol eluents, with three variations of eluent, namely: Eluent I chloroform: ethyl acetate: ethanol (80:5:15), Eluent II chloroform: ethyl acetate: ethanol (85:10:5) and Eluent III chloroform: ethyl acetate: ethanol (90:5:5). The research stage was carried out by preparing test samples from pandan leaf ethanol extract, then isolation was carried out. Testing was carried out by column chromatography method to separate chlorophyll compounds, the isolate obtained was then identified for the presence of chlorophyll by uv-vis spectrophotometry method to determine the maximum peak at a wavelength of 665 nm. Based on the results of the study, the ethanol extract of pandan leaves was green in color and had a distinctive aroma of pandan leaves as much as 90 ml. The elution results obtained a green band suspected of being chlorophyll obtained as much as 30 ml with an elution time of 3 minutes 52 seconds. The results of the identification test with uv-vis spectrophotometry obtained a maximum wavelength at a wavelength of 665 nm and an absorbance value of 0.550. From the results of the study, it can be concluded that pandan leaf juice contains chlorophyll compounds and can be isolated by column chromatography method with a mixture of chloroform, ethyl acetate and ethanol eluents.
Identification of Off-label Drug Prescription for Inpatient Pediatric Patients at Ciamis Regional Hospital Puspitasari, Yusi
Ad-Dawaa : Journal of Pharmacy Vol. 2 No. 2 (2024): Ad-Dawaa: Journal of Pharmacy (November 2024)
Publisher : LPPM STIKes Muhammadiyah Ciamis

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.52221/dwj.v2i2.735

Abstract

Rational and appropriately indicated drug administration to each patient is an effort to provide quality health services in hospitals and provide optimal therapy for patients. In reality, in some places there are drugs that are prescribed but do not comply with official drug information and do not comply with what is stated in the distribution permit, which are called off-label drugs. Drugs are categorized as off-label indications if the drugs used are outside the indications stated in the leaflet. The purpose of this study was to determine the description of off-label drug prescriptions for pediatric patients at General Hospitals in the Ciamis Region. Data collection on off-label drug prescriptions was carried out retrospectively, by taking inclusion and exclusion data, which were in accordance with the criteria for rational drug use. The sampling technique used was total sampling, namely taking data from medical records of inpatient pediatric patients from November to April. Data processing was carried out using descriptive analysis. The samples used were all prescriptions received that met the inclusion and exclusion criteria for pediatric patients. Of the 1,461 drug prescription samples obtained, no prescription of off-label indication drugs was found in pediatric patients. In other words, 100% of the samples were included in the list of drugs in the on-label indication category. From this study, it can be concluded that no prescription of off-label indication drugs was found in pediatric inpatients at Ciamis Regional Hospital.
Evaluation of the rationality of using antibiotics in orthopedic surgery patients at the Cilacap Regional General Hospital using the Gyssens method Permana, Fadli Bayu; Sofiah, Siti Asadu; Salfia, Wa Ode; Nurkholis, Fiqih
Ad-Dawaa : Journal of Pharmacy Vol. 2 No. 2 (2024): Ad-Dawaa: Journal of Pharmacy (November 2024)
Publisher : LPPM STIKes Muhammadiyah Ciamis

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.52221/dwj.v2i2.765

Abstract

A fracture is a condition of severing or damage to the cartilage, bone structure, or epiphysis, which is divided into open and closed fractures. Open fractures require antibiotic therapy to prevent infection, given the high risk of infection. Evaluation of the rationality of antibiotic use is very important to ensure effective therapy and prevent side effects, ineffective treatment, high costs, and antibiotic resistance. Antibiotic resistance can increase infections that are difficult to treat and increase morbidity and mortality. This study aims to evaluate the rationality of antibiotic use in orthopedic surgery patients at Cilacap Regional Hospital using the Gyssens method. The study was observational and collected retrospective data from 55 patients who underwent orthopedic surgery for open fractures in 2023. The data used for analysis included patient identity, diagnosis, laboratory data, and antibiotic use. The results obtained were category 0 (appropriate and rational use of antibiotics) 37%, category II A (inappropriate dosage) 10%, category II B (inappropriate administration interval) 1%, category III B (administration of antibiotics too short) 9%, category IV A (presence of other more effective antibiotics) 1%, category IV C (presence of cheaper antibiotics) 39%, category VI (incomplete patient data) 4%. The conclusion shows that there are still many antibiotic prescriptions that do not meet category 0, indicating the need for improvement in the rationality of antibiotic use at Cilacap Regional Hospital.
Evaluation of Waiting Time for Non-Concoction Electronic Prescriptions for Patients at The Outpatient Pharmacy Installation of Tasik Medika Citratama Hospital, Tasikmalaya City Fauzi, Muhammad Imam; Ramdan, Susan Sintia; Purwati, Ita
Ad-Dawaa : Journal of Pharmacy Vol. 3 No. 1 (2025): Ad-Dawaa: Journal of Pharmacy (May 2025)
Publisher : LPPM STIKes Muhammadiyah Ciamis

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.52221/dwj.v3i1.867

Abstract

The waiting time is one of the minimum standards for pharmaceutical services in hospitals, the waiting time for non-concocted drug services is the grace period from the time the patient submits the prescription to the time of receiving the non-concocted drug with the minimum standard set by the Ministry of Health, which is less than 30 minutes. The aim of this study is to determine the suitability of the waiting time for outpatient non-compound electronic prescription services at the Pharmacy Installation of Tasik Medika Citratama Hospital with the minimum standards stipulated in the Decree of the Minister of Health No. 129 of 2008 concerning Minimum Hospital Service Standards. This study is a prospective observational study using the Probability Sampling method by taking samples using quote sampling according to the inclusion criteria. The data taken were 260 non-compound electronic prescriptions. The average waiting time for non-compound electronic prescription services was 25.19 minutes. This meets the Minimum Hospital Service Standards according to the Decree of the Minister of Health No. 129 of 2008.
Determination of Salt Content in Salted Fish in Pangandaran Area Using Argentometric Titration Method Lukmansyah, Luki; Ramdani, Riva Aulia
Ad-Dawaa : Journal of Pharmacy Vol. 3 No. 1 (2025): Ad-Dawaa: Journal of Pharmacy (May 2025)
Publisher : LPPM STIKes Muhammadiyah Ciamis

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.52221/dwj.v3i1.868

Abstract

Salted fish is a traditional processed food widely consumed in Indonesia due to its affordability, availability, distinctive flavor, and long shelf life. However, despite its popularity, excessive salt used in preservation can lead to serious health issues such as hypertension, kidney problems, and cardiovascular diseases. Therefore, monitoring the salt content in these foods is essential for public health and food safety. This study aims to determine the sodium chloride (NaCl) levels in three commonly consumed salted fish types jambal roti (Arius thalassinus), layang (Decapterus sp.), and layur (Trichiurus sp.), sold in traditional markets and local traders (UMKM) in Pangandaran. It also evaluates whether these products meet the Indonesian National Standard (SNI 8273 2016), which requires salt levels to be between 12% and 20%. The analysis used the Mohr argentometric titration method, with silver nitrate (AgNO3) as the titrant and potassium chromate (K2CrO4) as the indicator. Samples were prepared by grinding, hot water extraction, and titration to measure salt content. Results showed salt levels ranged from 0.514% to 2.17%, with the highest in jambal roti from UMKM I and the lowest in jambal roti from UMKM II. All samples had salt levels well below the minimum standard of the SNI. These findings suggest that while the products are safe regarding sodium chloride levels, the low salt content may imply inadequate preservation, which could affect product stability and shelf life without other preservation methods. Further research is recommended to assess microbial safety and storage quality of these products.

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