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Evaluation of the rationality of using antibiotics in orthopedic surgery patients at the Cilacap Regional General Hospital using the Gyssens method Permana, Fadli Bayu; Sofiah, Siti Asadu; Salfia, Wa Ode; Nurkholis, Fiqih
Ad-Dawaa : Journal of Pharmacy Vol. 2 No. 2 (2024): Ad-Dawaa: Journal of Pharmacy (November 2024)
Publisher : LPPM STIKes Muhammadiyah Ciamis

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.52221/dwj.v2i2.765

Abstract

A fracture is a condition of severing or damage to the cartilage, bone structure, or epiphysis, which is divided into open and closed fractures. Open fractures require antibiotic therapy to prevent infection, given the high risk of infection. Evaluation of the rationality of antibiotic use is very important to ensure effective therapy and prevent side effects, ineffective treatment, high costs, and antibiotic resistance. Antibiotic resistance can increase infections that are difficult to treat and increase morbidity and mortality. This study aims to evaluate the rationality of antibiotic use in orthopedic surgery patients at Cilacap Regional Hospital using the Gyssens method. The study was observational and collected retrospective data from 55 patients who underwent orthopedic surgery for open fractures in 2023. The data used for analysis included patient identity, diagnosis, laboratory data, and antibiotic use. The results obtained were category 0 (appropriate and rational use of antibiotics) 37%, category II A (inappropriate dosage) 10%, category II B (inappropriate administration interval) 1%, category III B (administration of antibiotics too short) 9%, category IV A (presence of other more effective antibiotics) 1%, category IV C (presence of cheaper antibiotics) 39%, category VI (incomplete patient data) 4%. The conclusion shows that there are still many antibiotic prescriptions that do not meet category 0, indicating the need for improvement in the rationality of antibiotic use at Cilacap Regional Hospital.
Implementation of Interprofessional Health Education-based Research Based on Discipline, Practice, Dissemination Trends and Research Design: A Literature Review Nurkholis, Fiqih
KIAN JOURNAL Vol 2 No 2 (2023): KIAN JOURNAL (September 2023)
Publisher : Yayasan Inspirasi El Burhani

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.56359/kian.v2i2.308

Abstract

Objective: The World Health Organization (WHO) started a program in 2007 to promote Interprofessional Education (IPE) and its benefits for collaborative practice. Many IPE reviews have examined what has been done and how effective it is. This review aimed to investigate the methods and outcomes of IPE research. Methods: IPE research examined the following: 1) disciplines involved; 2) writing patterns, 3) assessment focus, and 4) dissemination trends. Abstracts were screened prior to full-text screening, review, data extraction, analysis and audit. Categorical data were reported with frequencies and percentages while continuous data were reported with means and standard deviations. Chi-square analysis was used to test for differences between groups for categorical variables. Results: Of the 359 articles that met the criteria, most were written by authors from medical, nursing, and pharmacy schools, using quantitative or mixed techniques. Most studies involved student disciplines with no authors from those disciplines. Most studies also measured student perceptions and knowledge, with a few measuring faculty perceptions. Research was mostly conducted in classrooms, simulations, and field experiences. IPE research was published in 98 journals, most of which were interdisciplinary journals, with the largest increase in publications in the last year of the review. Conclusions: The field of IPE research has grown significantly in the last decade. It is important to explore different ways to conduct IPE research, plan ways to disseminate IPE results, and ensure that all disciplines of students involved in IPE are represented in authorship.
Evaluasi Penggunaan Obat Pada Pasien Geriatri Yang Memiliki Kemungkinan Interaksi Obat Berdasarkan Beers Criteria Di Rumah Sakit Umum Daerah Cilacap Adityas, Hanung Puspita; Nurkholis, Fiqih; Hartono, Nurvadila Iqmalia
Indonesian Journal of Medical and Pharmaceutical Science Vol. 4 No. 1 (2025)
Publisher : Sultan Agung Islamic University of Semarang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30659/ijmps.v4i1.212

Abstract

Background: The increasing elderly population poses its own challenges, particularly in the field of health. The elderly tend to experience degenerative diseases and often have multiple chronic conditions. This can lead to the use of multiple medications (polypharmacy). Drug interactions occur when one medication affects the activity of another. These interactions can be pharmacokinetic or pharmacodynamic. The Beers Criteria is a tool used to detect Potentially Inappropriate Medications (PIMs) and identify drugs that may pose greater risks than benefits for elderly patients aged ≥ 65 years. Methods: This research uses descriptive method and is an observational study with a cross-sectional approach, measuring variables by collecting data through patient geriatric questionnaire. It aims to evaluate medication use in geriatric patients who may have drug interactions at Cilacap Regional General Hospital. Results: This research shows that female patients are more numerous, with 53 individuals (53.53%), while male patients amount to 46 individuals (46.46%). Patients in the age range of 60-74 years are 94 individuals (94.94%), and those in the age range of 75-90 years are 50 individuals (5.05%). Patients receiving <5 medication therapy are 57 individuals (57.57%), while those receiving >5 medications are 42 individuals (42.42%). The most commonly used medication among geriatric patients is candesartan, with 46 prescriptions (9.82%). The research results indicate that the medications falling under Potentially Inappropriate Medications (PIMs) according to the 2023 Beers criteria are mostly in category 1, totaling 81 medications (50.63%). Conclusion: The occurrence of Potentially Inappropriate Medications (PIMs) in geriatric patients at the outpatient department of Cilacap Regional General Hospital during the period of July-August 2024, based on the Beers Criteria 2023, shows that the largest percentage is attributed to glimepiride with 25 cases (17.606%). This indicates that prescribing PIMs to geriatric patients still involves potentially inappropriate drugs, necessitating attention from healthcare professionals to ensure safe and effective prescribing for this population.
Tingkat Penggunaan Antibiotik dan Pola Peresepannya Pada Infeksi Saluran Pernapasan (ICD-10: J00-J99) di Indonesia Selama Pandemi COVID-19 Misworo, Misworo; Kusuma, Ikhwan Yuda; Kurniasih, Khamdiyah Indah; Nurkholis, Fiqih; Fauziah , Fauziah
Journal of Pharmaceutical and Sciences JPS Volume 8 Nomor 2 (2025)
Publisher : Fakultas Farmasi Universitas Tjut Nyak Dhien

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36490/journal-jps.com.v8i2.849

Abstract

Introduction: Respiratory tract infections (RTIs) contribute substantially to global antibiotic consumption, raising concerns about antimicrobial resistance (AMR). This study aimed to analyze antibiotic prescribing patterns for respiratory disorders in an Indonesian teaching hospital during the COVID-19 pandemic. Methods: This retrospective, cross-sectional study examined systemic antibiotic prescriptions based on the Anatomical Therapeutic Classification (ATC: J01) for respiratory diseases (ICD-10: J00-J99) at Cilacap Government Teaching Hospital between January and December 2021. Data were extracted from electronic medical records (e-MR), including patient demographics (i.e. age and sex), ICD codes and name of antibiotics. We analyzed WHO AWaRe classifications, administration routes, and seasonal patterns based on patient’s entry and antibiotic use. Results: The study included 2,395 patients with antibiotic prescriptions for respiratory disorders. The Watch group antibiotics accounted for 85.6% of prescriptions, with the highest use among adults (86.2%). Parenteral administration (71.5%) was more common than oral administration (28.5%). Pneumonia (38.2%) and chronic obstructive pulmonary disease (27%) were the most common indications. Antibiotic use peaked in December (n=529) and was lowest in July (n=84). Ceftriaxone (n=838), azithromycin (n=270), cefixime (n=262), levofloxacin (n=216), and meropenem (n=56) were among the top prescribed antibiotics. Conclusion: The study highlights the predominant use of broad-spectrum and parenteral antibiotics for respiratory disorders, raising concerns about AMR. Factors such as seasonality, disease patterns, and diagnostic challenges may have influenced prescribing practices. Implementing antimicrobial stewardship programs, promoting evidence-based guidelines, and addressing modifiable risk factors are crucial to combat AMR and optimize patient outcomes during and beyond the COVID-19 pandemic.
Pelatihan Pemanfaatan Limbah Minyak Jelantah Menjadi Lilin Aromaterapi Di Desa Windujaya Kurniasih, Khamdiyah Indah; Samodra, Galih; Setianingsih, Siti; Nurkholis, Fiqih; Hakim, Lukman
Jurnal Pengabdian Masyarakat Farmasi : Pharmacare Society Vol 4, No 1 (2025)
Publisher : State University of Gorontalo

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37905/phar.soc.v4i1.31247

Abstract

Minyak jelantah adalah minyak yang telah digunakan secara berulang-ulang hingga 3-4 kali penggorengan. Dampak negative dari minyak goreng bekas jika dibuang begitu sajatanpapengolahanakanmenjadilimbahdanakanmerusaklingkungansekitar.Salahsatubentuk  produk hasil pengolahan minyak goreng bekas adalah lilin aromaterapi. Sasaranmitra  pengabdian ini adalah masyarakat ekonomi non produktif di desaWindujaya yang bekerja bekerja sebagai Ibu Rumah Tangga dan tidak memiliki penghasilan. UrgensiPemberdayaan Masyarakat Pemula ini meningkatkan keterampilan Kelompok Kader DesaWindujaya dalam Pelatihan Pembuatan lilin aromaterapi yang berbahan dasar limbah minyak jelantah. Tujuan kegiatan ini yaitu, meminimalisasipembuangan minyak jelantah, berubahnya pola hidup masyarakat untuk mengolah limbahminyak jelantah berbasis zero waste industry, berkurangnya pembuangan minyak jelantahdisembarang tempat dapat mengurangi resiko pencemaran air tanah, dan erciptanya produklilinaromaterapidansabunbernilaiekonomis. Kegiatan ini telah terlaksana pada tanggal 18 agustus 2024 dengan peserta ibu rumah tangga yang ada di Desa Winduajaya, Banyumas. Metode Kegiatan ini menggunakan metode difusi ilmu pengetahuan dan teknologi (ipteks) dengan tahapan berupa tahapan persiapan dan koordinasi terkait dengan pengetahuan Masyarakat terhadap lombah minyak jelantah ,Pemberdayaan Masyarakat, monitoring dan evaluasi serta sasaran pelatihan.  Hasil pengabdian didapat bahwa terdapat peningkatan pengetahuan terkait pemanfaatan limbah minyak jelantah dalam bentuk lilin aromaterapi.