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Medical Laboratory Journal
Published by Sekolah Tinggi Ilmu Kesehatan Kesetiakawanan Sosial Indonesia
ISSN : 30265754     EISSN : 30265746     DOI : 10.57213
Core Subject : Health,
Health Professions Public Health
Jurnal ini adalah Jurnal Kalori : Jurnal Laboratorium Medis yang bersifat peer-review dan terbuka. Bidang kajian dalam jurnal ini meliputi Laboratorium Kedokteran. Jurnal Kalori
Arjuna Subject : Kedokteran - Kedokteran (Lain-Lain)
Articles 71 Documents
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CPOB Sediaan Steril Dewi Rahmawati; Dzakiya Zhihrotulwida; M. Fitrul Mubarak; Ismatun Maulidiyah; Elsa Saqila; Aprilia Puji; Ika Hepi; Silvi Novita Permatasari
Medical Laboratory Journal Vol. 2 No. 4 (2024): December : Medical Laboratory Journal
Publisher : LPPM STIKES KESETIAKAWANAN SOSIAL INDONESIA

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.57213/caloryjournal.v2i4.507

Abstract

The importance of Good Manufacturing Practices (GMP) in the pharmaceutical industry to ensure the quality and safety of drug products. GMP aims to ensure that all pharmaceutical preparations, including sterile drugs such as infusions and injections, meet strict quality standards. Sterility testing is an important aspect even though it has limitations, such as long incubation times and low probability of detecting contamination. Therefore, any sterility test results that do not meet the requirements must be further investigated to find the cause, either from laboratory errors or contamination in the production process. In addition, the implementation of technical and managerial aspects in accordance with GMP, such as temperature and humidity control, is very important to maintain product quality. This article also highlights the use of modern technologies, such as Service Oriented Architecture (SOA), to improve efficiency and transparency in the drug production process, so that it can meet all the provisions set.
Perbandingan Efektivitas Lama Waktu Suction Pada Pasien Yang Terpasang Endotrakeal Tube Terhadap Saturasi Oksigen Pada Pasien di Ruang Operasi Naufal Annasy; Ika Kusuma Wardani; Aresta Rahma Mutaqina
Medical Laboratory Journal Vol. 2 No. 2 (2024): June : Medical Laboratory Journal
Publisher : LPPM STIKES KESETIAKAWANAN SOSIAL INDONESIA

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.57213/caloryjournal.v2i2.513

Abstract

Background : endotracheal tube suction is an intervention that is often performed by nurses to help with airway patency. Patients who have an endotracheal tube installed allow the accumulation of secretions so that suction is carried out with duration of 10 seconds and 15 seconds. Purpose : the study was to determine the effectiveness of increasing oxygen saturation values before and after suctioning for 10 seconds and 15 second in patients with endotracheal tubes. Methods : the research method for type of research uses a quasi-experimental research design using a pre-test and post-test with group design. The number of respondents in this study were 30 people. Oxygen saturation values were measured using and data analysis using univariate and bivariate analysis was perfomed to determine the frequency distribution of the characteristics of the respondents while bivariate analysis used the Shapiro wilk test. Result : there was no significant difference in the group with a suction time of 10 seconds and 15 seconds in patient with a suction time of 10 seconds in the value of oxygen saturation with p value (p>0.05)=0.059. Recommendation : long suction time of 10 seconds can increase the saturation value oxygen
Uji Perbandingan Aktivitas Antibakteri Ekstrak Daging Buah, Kulit Buah dan Daun Pala Hutan (Myristica Schifferi Warb) terhadap Escherichia Coli Wiwi Rumaolat; Mohammad Dahlan Sely
Medical Laboratory Journal Vol. 2 No. 4 (2024): December : Medical Laboratory Journal
Publisher : LPPM STIKES KESETIAKAWANAN SOSIAL INDONESIA

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.57213/caloryjournal.v2i4.591

Abstract

Nutmeg belongs to the Myristicaceae family which consists of 15 genera and 250 species. Nutmeg has several benefits for body health, namely, Improving brain health, Overcoming digestive problems, Maintaining oral health, Treating insomnia. Escherichia coli is a bacterial name taken from the name of the person who discovered it, Theodor Escherich. This study aims to determine the comparison of antibacterial activity of forest nutmeg pulp, peel and leaf extract (Myristica schifferi Warb) against Escherichia coli.: The research method used is the agar diffusion method. The results of the antibacterial activity test of the flesh and skin of forest nutmeg (Myristica schifferi Warb) against Escherichia coli bacteria with concentrations of 50%, 75% and 100% were declared sensitive to inhibit the growth of Escherichia coli bacteria. Meanwhile, the results of the forest nutmeg leaf test with a concentration of 50% were declared intermediate or medium category to inhibit the growth of Escherichia coli bacteria, for concentrations of 75% and 100% were declared sensitive to inhibit the growth of Escherichia coli bacteria.
Hubungan Suplemen Tablet Tambah Darah sebagai Pemenuhan Gizi Mikro Terhadap Potensi Stunting di Negara Indonesia; Tinjauan Sistematis Literatur Zeni Dermawan; Indra Permana; Sri Setiatjahjati
Medical Laboratory Journal Vol. 3 No. 1 (2025): March : Medical Laboratory Journal
Publisher : LPPM STIKES KESETIAKAWANAN SOSIAL INDONESIA

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.57213/caloryjournal.v3i1.589

Abstract

Background: Iron-containing blood-boosting tablet supplements are crucial for meeting micronutrient needs in pregnant women and children. Micronutrient deficiencies, such as iron, have the potential to cause stunting. This supplementation program is expected to improve the nutritional status of the Indonesian population, prevent stunting, and support optimal growth.Objective: This systematic literature review aims to analyze the relationship between iron-boosting tablet supplements in meeting micronutrient needs and preventing stunting in children (toddlers and infants) in Indonesia.Method: A systematic literature search was conducted to identify relevant articles in 3 main databases (Scopus, PubMed, and Google Scholars). Studies on the consumption of iron-boosting tablets for meeting micronutrient needs in stunting cases require a systematic review with inclusion criteria limited to articles published between 2015-2024, free full text, in Indonesian and English.Results: Of the 10 articles analyzed, most showed that consumption of Iron-Boosting Tablets (TTD) in pregnant women can increase hemoglobin levels and reduce the risk of anemia, which contributes to the prevention of stunting in children. However, the compliance rate of pregnant women in consuming TTD is still low due to side effects and lack of awareness. Additionally, socio-economic factors also play a role in children's nutritional status, where families with low incomes have a higher risk of anemia and stunting.Conclusion: TTD supplementation plays an important role in the prevention of anemia and stunting in children. However, its effectiveness is greatly influenced by the level of consumption compliance and socio-economic factors. Therefore, more intensive education and multi-sectoral policies are needed to improve accessibility and compliance with TTD consumption in stunting prevention efforts in Indonesia.    
The Impact of Social Marginalization on Mental Health in Middle Eastern Conflict Zones Nurzahara Sihombing; M. Agung Rahmadi; Helsa Nasution; Luthfiah Mawar
Medical Laboratory Journal Vol. 3 No. 2 (2025): June : Medical Laboratory Journal
Publisher : LPPM STIKES KESETIAKAWANAN SOSIAL INDONESIA

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.57213/caloryjournal.v3i2.623

Abstract

This systematic review aims to comprehensively evaluate the consequences of social marginalization on the mental health conditions of populations in Middle Eastern conflict zones, utilizing data from 2015 to 2024. Through a critical examination of 47 studies that met the inclusion criteria, a markedly high prevalence of mental disorders within this population was identified, namely post-traumatic stress disorder (PTSD) at 42.8% (95% CI = 38.4–47.2), major depression at 37.6% (95% CI = 33.2–42.0), and generalized anxiety disorder at 35.3% (95% CI = 31.1–39.5). Furthermore, the results of the meta-analysis revealed a very strong and statistically significant correlation between social marginalization and the severity of mental health disorders (r = 0.73, p < 0.001), indicating that the more intensely an individual experiences various forms of social marginalization, the more severe the psychological disorders they endure. Moreover, the three most dominant determinants of social marginalization were identified as limited access to healthcare services (OR = 3.82, 95% CI = 3.14–4.50), the persistence of systemic discrimination (OR = 3.45, 95% CI = 2.87–4.03), and widespread social isolation (OR = 3.21, 95% CI = 2.66–3.76). These findings not only expand upon the prior research outcomes of Al-Krenawi and Graham (2009) and Amsalem et al. (2025), which were confined to the aspect of PTSD but also provide new empirical evidence concerning a broader spectrum of mental disorders as well as specific patterns of social marginalization within the conflict landscape of the Middle East. Finally, this study contributes significantly to the academic literature by elaborating on the complex interactive mechanisms between practices of social marginalization and mental health deterioration while offering a framework for community-based interventions that are responsive and adaptive to the socio-political conditions characteristic of Middle Eastern conflict zones.
Analisis Sistematis Faktor Sosial Dalam Perilaku Merokok Remaja :  kajian pada kelompok usia 10-18 tahun Aulia Chintya Sari; Andriyani
Medical Laboratory Journal Vol. 3 No. 2 (2025): June : Medical Laboratory Journal
Publisher : LPPM STIKES KESETIAKAWANAN SOSIAL INDONESIA

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.57213/caloryjournal.v3i2.647

Abstract

Rokok adalah salah satu barang yang berbahaya yang paling mematikan di dunia mengkonsumsi rokok secara berkelanjutan dapat mengakibatkan berbagai masalah kesehatan. Rokok di bedakan menjadi tiga jenis berdasarkan bahan bakunya yaitu rokok putih , rokok kretek dan rokok klembek. Faktor merokok pada remaja yaitu dari faktor interpersonal yang terdiri dari pengaruh teman sebaya. Pengaruh keluarga. Dukungan informasi dan dukungan appraisal. Tujuan dalam penelitian ini yaitu untuk mengetahui sistematis faktor sosial dalam perilaku merokok remaja dan pada penelitian kali ini saya menggunakan metode literature riview dengan meneliti berbagai jurnal yang di publikasikan pada tahun 2020-2025 dengan menggunakan database seperti Google Scholar Web garuda dan PuMed. Merokok di usia muda banyak sekali yang membuat sakit untuk itu dukungan orang tua terhadap anaknya merupakan faktor pengaruh sosial yang paling besar untuk remaja agar tidak merokok. Saran untuk penelitian ini yaitu dapat lebih bervariasi lagi untuk database agar lebih mengetahui lebih banyak tentang faktor yang di sebabkan oleh rokok itu sendiri dan mungkin lebih dalam lagi untuk pembahasan mengenai masalah merokok di kalangan remaja.  
Comparative Study of HPLC Detectors in PT. FIP : A Review Annisa Luthfiyah Handini; Patihul Husni; Indriana Agustin Claradila Frinda
Calory Journal Medical Laboratory Journal Vol. 3 No. 2 (2025): June : Medical Laboratory Journal
Publisher : LPPM STIKES KESETIAKAWANAN SOSIAL INDONESIA

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.57213/caloryjournal.v3i2.648

Abstract

High Performance Liquid Chromatography (HPLC) is a vital analytical technique used for separation, identification, and quantification of compounds in complex mixtures. This review explores the comparative performance of four detectors employed in the Chemical Laboratory of PT FIP: UV-Visible, Refractive Index (RI), Conductivity, and Evaporative Light Scattering Detector (ELSD). Each detector operates on distinct principles and is selected based on analyte characteristics such as the presence of chromophores, ionic nature, or volatility. The UV-Vis detector remains the most widely used due to its precision and compatibility with chromophoric compounds. However RI, Conductivity, and ELSD detectors serve as essential alternatives for analytes that lack UV absorption, non-ionizing, or exhibit low volatility. This review summarizes the key principles, advantages, limitations, and applications of each detector. The comparative evaluation highlights the strengths and constraints of each system, facilitating method optimization in pharmaceutical analysis.
HIV/AIDS Harda Afif Franda Sinaga
Medical Laboratory Journal Vol. 3 No. 2 (2025): June : Medical Laboratory Journal
Publisher : LPPM STIKES KESETIAKAWANAN SOSIAL INDONESIA

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.57213/caloryjournal.v3i2.653

Abstract

Human Immunodeficiency Virus (HIV) is a retrovirus that targets the human immune system, particularly cells with CD4 receptors such as T lymphocytes, monocytes, and macrophages. This virus causes progressive damage to the immune system and, if left untreated, can develop into Acquired Immunodeficiency Syndrome (AIDS). HIV is transmitted through sexual contact, blood transfusions, shared needles, and from mother to child during pregnancy, childbirth, or breastfeeding. HIV has become a global pandemic, with over 39 million people living with the virus in 2022. In Indonesia, the HIV epidemic is diverse, with high-risk groups including injection drug users, men who have sex with men, sex workers, and transgender individuals. The pathogenesis of HIV involves infection of immune cells, integration of viral DNA into the host genome, and production of new virions, leading to a gradual decline in immune function. HIV diagnosis is conducted through serological and virological testing, while antiretroviral therapy (ART) is the standard treatment to suppress viral replication, preserve immune function, and improve patients' quality of life and life expectancy. Early detection and proper management of HIV are crucial to preventing progression to AIDS and reducing transmission within the population.
Neoplasma Ovarium Kistik Muhammad Syifa Albi Nasution
Medical Laboratory Journal Vol. 3 No. 2 (2025): June : Medical Laboratory Journal
Publisher : LPPM STIKES KESETIAKAWANAN SOSIAL INDONESIA

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.57213/caloryjournal.v3i2.654

Abstract

Ovarian cysts are ovarian tumors that can be either neoplastic or non-neoplastic, with varying characteristics in terms of size, consistency, and malignancy. During pregnancy, the most commonly encountered types include dermoid cysts, endometriomas, and lutein cysts. The actual prevalence of ovarian cysts is difficult to determine as most cases remain undiagnosed, with studies indicating that around 4% of women will experience hospitalization due to ovarian cysts by the age of 65. Evaluation of ovarian masses requires a multidisciplinary approach, including ultrasonography and tumor markers to assess the likelihood of malignancy. This case involves a 45-year-old woman who presented with lower abdominal pain, bloating, and significant weight loss. Ultrasound findings revealed a cystic mass with solid components, suspected to be a malignant ovarian cyst. The provisional diagnosis was cystic ovarian neoplasm with suspected malignancy, and the patient underwent laparotomy with right salphingo-oophorectomy. Post-surgery, the patient's condition improved, though she continued to experience pain at the surgical site. Ovarian cysts can present with nonspecific symptoms and are often found incidentally. Further evaluation is necessary to assess malignancy and determine appropriate treatment. Surgical intervention is required for cases with suspected malignancy, especially in cysts with solid masses and large size.
Intersectionality of Gender, Social Class, and War Trauma in the Middle East : A Multilayer Analysis Helsa Nasution; M. Agung Rahmadi; Luthfiah Mawar; Nurzahara Sihombing
Medical Laboratory Journal Vol. 3 No. 2 (2025): June : Medical Laboratory Journal
Publisher : LPPM STIKES KESETIAKAWANAN SOSIAL INDONESIA

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.57213/caloryjournal.v3i2.656

Abstract

This multilayer meta-analysis investigates the intersectionality between gender, social class, and war-related trauma in the Middle East through a systematic review of 87 studies (N = 31,459) published between 2000 and 2023. Analytical findings reveal a strong and significant correlation between gender and trauma severity (r = 0.67, p < 0.001), with women experiencing a 2.8 times higher prevalence of PTSD compared to men. Furthermore, results from hierarchical regression demonstrate that social class functions as a substantial moderator (β = 0.45, p < 0.001), with individuals from lower social class backgrounds exhibiting a 3.2 times greater risk of trauma. Further structural path analysis reveals the presence of dual mediation (CFI = 0.96, RMSEA = 0.04), with access to mental health services and social support serving as primary mediators (indirect effect = 0.38, 95% CI [0.29, 0.47]). These results expand the contributions of Al-Krenawi and Graham (2012) and Mangrio et al. (2019) by illustrating the complex interaction of the three dimensions (Gender, Social Class, and War Trauma), which had previously been examined only separately. In addition, this study identifies a new pattern termed the "spiral trauma effect," a mechanism wherein the intersectionality of gender, social class, and trauma mutually reinforce each other in a recurring cycle (effect size d = 0.89), thereby deepening the understanding of trauma dynamics in conflict zones across the Middle East. Finally, the predictive model developed in this research demonstrated an accuracy rate of 84.3% in identifying high-risk individuals. Thus, these results are considered to provide an innovative framework for the development of empirically-based trauma interventions in Middle Eastern war zones.

Page 6 of 8 | Total Record : 71

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