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Vania Snatika Putri
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INDONESIA
Jurnal Farmasindo: Jurnal Penelitian dan Pengabdian Masyarakat
Published by Politeknik Indonusa Surakarta
ISSN : 25486667     EISSN : 27759032     DOI : 10.46808
Core Subject : Health, Science,
Health Professions Immunology & microbiology Materials Science & Nanotechnology Medicine & Pharmacology Public Health
The journal includes various fields of pharmaceuticals sciences such as: Pharmacy, Pharmacokinetics, Community and Clinical Pharmacy, Medical, Alternative medicines, Synthetic Organic Chemistry, Organic Chemistry of Natural Material, Biochemistry, Chemical Analysis, Microbiology, Tissue Culture, Botany and Animals Related to Pharmaceutical Products, Midwifery, Health Analyst, Nutrition and Public Health, Pharmacology and Toxicology
Arjuna Subject : Pharmacology, Toxicology and Pharmaceutics - Pharmacology, Toxicology and Pharmaceutics (Lain-Lain)
Articles 162 Documents
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EFEKTIVITAS PENGGUNAAN RAMUAN JAMU DALAM BENTUK REBUSAN DAN KAPSUL TERHADAP PENURUNAN KADAR KOLESTEROL PASIEN HIPERKOLESTEROLEMIA Ovikariani Ovikariani; Agustina Dwiyanti; Retnowati Adiningsih
Jurnal Farmasindo: Jurnal Penelitian dan Pengabdian Masyarakat Vol. 10 No. 1 (2026): Juni
Publisher : Politeknik Indonusa Surakarta, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.46808/farmasindo.v10i1.284

Abstract

Hypercholesterolemia is one of the main risk factors for cardiovascular disease, which is the leading cause of death in Indonesia. Herbal concoctions are an alternative therapy that is considered safer, more affordable, and has minimal side effects. This study aims to determine the effectiveness of using herbal concoctions in the form of decoctions and capsules in reducing cholesterol levels in patients with mild hypercholesterolemia at the Hortus Medicus Tawangmangu Herbal Science Clinic. This study used an analytical observational design based on medical records from 2024. A sample of 60 patients was divided into two groups of decoctions and capsules. Both preparations had the same composition: guava leaves, Chinese guava leaves, and tempuyung leaves with a therapy duration of 28 days. Data analysis used a paired t-test and an independent t-test. The paired t-test showed a difference between cholesterol levels before and after using the herbal concoction. In the decoction group, cholesterol levels decreased from 217.37 mg/dL to 196.17 mg/dL, while in the capsule group, cholesterol levels decreased from 217.17 mg/dL to 202.12 mg/dL with a p-value of 0.00 <0.05. The independent t-test showed an average decrease in cholesterol levels in the decoction group of 21.00 mg/dL, while in the capsule group it was 14.90 mg/dL, with a p-value of 0.00 <0.05. This indicates that decoction is more effective than capsules in reducing total cholesterol levels. This research can be the basis for the development of more effective anti-cholesterol herbal preparations.
PERAN ZINK TERHADAP PENYAKIT GASTROENTERITI AKUT PADA ANAK DI DUNIA MENGGUNAKAN METODE SYSTEMIC LIRATURE Michelle Maria Wijayanty; Fadel Reza Sulaeman; Muhammad Nur Irsyad; July July
Jurnal Farmasindo: Jurnal Penelitian dan Pengabdian Masyarakat Vol. 9 No. 2 (2025): Desember
Publisher : Politeknik Indonusa Surakarta, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.46808/farmasindo.v9i2.286

Abstract

Acute gastroenteritis (GAE) is a significant global health problem, with children being the majority of cases, with high morbidity and mortality rates. Gastroenteritis is characterized by watery or almost watery diarrhea, accompanied by nausea and vomiting. In Indonesia, cases of AE in young children are increasing, partly due to a lack of awareness about hygiene. The pathophysiology of AE includes damage to the gastrointestinal mucosa due to infection by bacteria, viruses, or parasites, which causes increased fluid secretion and decreased absorption, leading to diarrhea. Several studies have found that zinc administration can shorten the healing time. This study aims to evaluate the role of zinc in the management of acute AE in children through a systematic literature review (SRB). The research method included a search for journal articles from 2015 to 2025 using the keyword "Acute Gastroenteritis in Children." A review of seven journals showed that zinc supplementation, at the recommended dose of 20 mg per day for children aged 6 months to 5 years, significantly reduced the duration and frequency of diarrhea, improved stool consistency, and increased intestinal resistance. Low zinc levels have been shown to be associated with diarrhea severity. Zinc contributes to the epithelialization of affected intestinal mucosa and could be a therapy to reduce unnecessary antibiotic use in cases of AE.
DETEKSI DAN KUANTIFIKASI LOGAM TEMBAGA (Cu) DALAM IKAN PATIN (Pangasianodon hypophthalmus) SUNGAI MUSI PALEMBANG MENGGUNAKAN METODE SPEKTROFOTOMETRI SERAPAN ATOM indah indah; Risa Astuti; Sarah Hanifah Az-Zahra Anwar
Jurnal Farmasindo: Jurnal Penelitian dan Pengabdian Masyarakat Vol. 9 No. 2 (2025): Desember
Publisher : Politeknik Indonusa Surakarta, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.46808/farmasindo.v9i2.287

Abstract

Copper (Cu) is a toxic heavy metal that can accumulate in aquatic organisms, including edible fish. The Patin fish (Pangasianodon hypophthalmus) is an effective bioindicator for assessing heavy metal contamination in the Musi River, Palembang. This study determined Cu concentrations in Patin fish collected from three locations: Kuto Batu, 10 Ulu, and 5 Ulu, using Atomic Absorption Spectrophotometry (AAS). Cu levels were 0.60819 mg/kg (Kuto Batu), 1.08638 mg/kg (10 Ulu), and 1.01736 mg/kg (5 Ulu), all within the maximum limits for food safety. However, these results highlight the potential for Cu exposure in the Musi River ecosystem, which may pose cumulative risks to food safety and public health if concentrations increase over time.
ANALISIS KESESUAIAN MANAJEMEN PENGELOLAAN LOGISTIK OBAT DI INSTALASI FARMASI RUMAH SAKIT ISLAM PURWOKERTO TAHUN 2024 Siti Asadu Sofiah M.Farm; Ayu Nawang Sari; Desy Arisandi Adelia
Jurnal Farmasindo: Jurnal Penelitian dan Pengabdian Masyarakat Vol. 9 No. 2 (2025): Desember
Publisher : Politeknik Indonusa Surakarta, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.46808/farmasindo.v9i2.289

Abstract

Drug management is an important element in pharmacy management that includes selection, planning, procurement, receipt, storage, distribution, disposal, control, recording, and reporting. This research aimed to analyze the suitability of drug logistics management in the pharmacy installation of Rumah Sakit Islam Hospital Purwokerto according to Permenkes Number 72 of 2016. A descriptive qualitative with data collection through interviews, checklists, and observations from informants such as the head of IFRS, coordinators, and TTK was used as a method in this research. The results showed that in terms of input, human resources reached 100%, while facilities and infrastructure were 75%. Several aspects need evaluation, such as logistics management training and additional storage space. The selection, planning, and distribution processes all reached 100%. However, procurement was only 80% due to the use of manual systems and e-catalogs that have not been fully implemented. Drug receipt reached 50% and storage 73.6%, where inadequate storage space caused accumulation. From those findings, there needs to be an improvement in the temperature recording system and labeling of high-alert drugs and LASA. In overall output, drug logistics management at Rumah Sakit Islam Hospital Purwokerto has met the criteria of good with 100% conformity, indicating effectiveness in drug management.
EFEKTIVITAS EDUKASI GIZI DALAM MENINGKATKAN PERILAKU IBU BALITA TENTANG PENCEGAHAN STUNTING DI DESA PANDAK, KABUPATEN SRAGEN Wahyu Ratri Sukmaningsih; Adhitya Wahyu Kurniawan; Nurlita Fauziah; Sri Rohmiyati; Zakiya Murni Setyawati; Munawwarah
Jurnal Farmasindo: Jurnal Penelitian dan Pengabdian Masyarakat Vol. 9 No. 2 (2025): Desember
Publisher : Politeknik Indonusa Surakarta, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.46808/farmasindo.v9i2.290

Abstract

Stunting is still a health priority in Indonesia and has an impact on children's physical growth, cognitive development, and long-term health. Although the national prevalence shows a downward trend, the achievement of the 2020-2024 RPJMN target has not been optimal so more effective nutritional intervention is needed, especially at the family level. This study aims to analyze the effectiveness of nutrition education in improving the knowledge, attitudes, and practices of toddler mothers related to stunting prevention in Pandak Village, Sragen Regency. The study used a quasi-experimental design with one group pretest-posttest on 30 purposively selected toddler mothers. Instruments include questionnaires of knowledge (15 item), attitudes (10 item), and practices (10 item) for which validity and reliability have been tested. Educational interventions are conducted through lectures, discussions, and demonstrations. Analysis of the data using the Wilcoxon test. The results showed a significant improvement in all variables after the intervention: the average knowledge score of 60 ± 8,5 to 85 ± 7,.2 (p = 0,000), the average attitude score of 65,2 ± 9,1 to 82,3 ± 6,8 (p = 0,001), the average practice score of 62,4 ± 10 to 84,7 ± 8,1 (p = 0,000). The pre-test and post-test took place on the same day. The measurement of practice in this study is self-reported. The proportion of categories both in knowledge, attitude, and practice increases meaningfully. This study concluded that nutrition education is effective in improving stunting prevention behavior in toddler mothers and is recommended to be implemented continuously in posyandu activities.
FORMULASI DAN EVALUASI SIFAT FISIK SEDIAAN LOTION HIDROSOL RIMPANG JAHE EMPRIT (Zingiber officinale var Amarum) Vania Santika Putri; Avita Oktaviani; Deva Yuliana; Monic Aulia
Jurnal Farmasindo: Jurnal Penelitian dan Pengabdian Masyarakat Vol. 9 No. 2 (2025): Desember
Publisher : Politeknik Indonusa Surakarta, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.46808/farmasindo.v9i2.291

Abstract

The hydrosol of Zingiber officinale var. Amarum (jahe emprit rhizome) contains active compounds such as flavonoids, tannins, phenols, saponins, and alkaloids, which have the potential to protect the skin against ultraviolet (UV) radiation. This study aims to formulate and evaluate the physical properties of lotion preparations based on jahe emprit rhizome hydrosol in three concentration variations: 30%, 40%, and 50%. The evaluation includes organoleptic tests, homogeneity, spreadability, adhesion, pH, and viscosity. The results of organoleptic and homogeneity tests from all three formulas indicate that the homogeneous preparations have similar color, odor, and form. All lotion preparations met the required standards, with pH values ranging from 7.36±1.42 to 7.75±1.18, and viscosities ranging from 9,947.6±2.25 to 27,035.4±1537.51 cPs. The best spreadability was observed in formula FIII (50%) at 6.07 cm, while the adhesion of all formulas was only 1 second. Statistical tests (Kruskal-Wallis and ANOVA) showed no significant effect of hydrosol concentration variations on the physical properties of the lotion. Thus, FIII is practically the best formula as it provides optimal spreadability, with its pH and viscosity being consistent with the required standards.
FORMULASI DAN EVALUASI FISIK SEDIAAN MASKER GEL PEEL OFF EKSTRAK ETANOL RIMPANG KUNYIT PUTIH (Curcuma Zedoaria) VARIASI KONSENTRASI PVA Vania Santika Putri; Ajeng Rizqi Amelia; Reva Vanestia Ningsih; Valda Isthiningstyas
Jurnal Farmasindo: Jurnal Penelitian dan Pengabdian Masyarakat Vol. 9 No. 2 (2025): Desember
Publisher : Politeknik Indonusa Surakarta, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.46808/farmasindo.v9i2.294

Abstract

White turmeric (Curcuma zedoaria) is a plant that contains secondary metabolite compounds such as flavonoids and saponins which are known to have antioxidant activity. Therefore, white turmeric extract has the potential to be used as an active substance in the manufacture of a peel-off gel mask preparation that is practical to use. The purpose of this study was to design and evaluate the physical characteristics of a peel-off gel mask preparation made from Curcuma zedoaria extract with varying concentrations of PVA as a film-forming agent. The extract was obtained through the maceration method using 96% ethanol solvent with a ratio of simplicia and solvent of 1:10. The variations in PVA concentration used were FI (10%), FII (12%), and FIII (14%). The physical results of the preparation showed that the peel-off gel mask preparation was light brown in color, had no aroma, had a gel texture, and showed physical properties that met the requirements with a pH value of FI = 6.28 ± 0.98; FII = 6.19 ± 0.28; FIII=5.76±0.32, spreadability FI=5.30±2.297 cm; FII=5.25±0.005 cm; FIII=5.24±0.065 cm, drying time in the range of 16.53-18.77 minutes and the adhesive power of the three formulas showed a time of more than 1 second. The results of statistical analysis showed that variations in PVA concentration had a significant effect on viscosity, but did not have a significant effect on pH, spreadability, drying time, and adhesive power.
FORMULASI DAN UJI AKTIVITAS ANTIBAKTERI SEDIAAN KRIM EKSTRAK ETANOL BUNGA PEPAYA JANTAN (Carica Papaya L.) Purwaningsih Purwaningsih; Umi Nafisah
Jurnal Farmasindo: Jurnal Penelitian dan Pengabdian Masyarakat Vol. 9 No. 2 (2025): Desember
Publisher : Politeknik Indonusa Surakarta, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.46808/farmasindo.v9i2.296

Abstract

Staphylococcus aureus bacteria are known to cause skin infections. One plant suspected of inhibiting or killing this bacteria is the male papaya flower. Papaya flowers contain active compounds including flavonoids, saponins, alkaloids, and tannins. These secondary metabolites can act as antibacterial agents. This research aimed to test the physical properties and antibacterial properties of an ethanol extract cream made from male papaya flowers and to determine the effect of the concentration of the extract on its ability to inhibit the growth of Staphylococcus aureus bacteria.           The extract was prepared using a soaking/maceration method using 96% ethanol as an organic solvent. Evaluation of the cream's physical properties included organoleptic tests, cream homogeneity, spreadability, adhesion, and protection. Antibacterial activity was tested using the disk diffusion method. The extract was formulated into a cream at concentrations of 5%, 10%, 15%, 20%, and 25%.           The results of the physical properties test showed that the ethanol extract cream made from male papaya flowers met the standards. Based on antibacterial tests, papaya flower ethanol extract cream was able to inhibit the growth of S. aureus bacteria. The minimum inhibition activity was 1.4 mm at a 5% concentration, and the highest inhibition was 13.9 mm at a 25% concentration
GAMBARAN PAPARAN IKLAN OBAT SWAMEDIKASI DAN HUBUNGAN TINGKAT PENGETAHUAN TERHADAP PERILAKU SWAMEDIKASI SAKIT KEPALA Fathul Muin; Ardhia Paramesti Faisa Putri
Jurnal Farmasindo: Jurnal Penelitian dan Pengabdian Masyarakat Vol. 9 No. 2 (2025): Desember
Publisher : Politeknik Indonusa Surakarta, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.46808/farmasindo.v9i2.298

Abstract

In order to take care of minor health issues without going to a doctor, self-medication is typical practice in the community. One of the most common health issues that people self-medicate with OTC medications is headache. There is a possibility that people's views and choices about medicine usage are impacted by the extensive exposure to drug advertisements in digital and electronic media. This study aims to examine the community’s experience with headache medication advertisements and analyze the relationship between knowledge level and self-medication behavior in Sleman Regency, Indonesia. The study used a cross-sectional design and a convenience sample of 159 people to administer an online questionnaire and gather data. To assess the correlation between the variables, descriptive statistics and a chi-square test were used. It was found that 68.6% of those who took the survey knew a lot about how to treat headaches on their own. There were significant correlations (p<0.05) between the amount of knowledge and the conduct of self-medication. The community had a high level of understanding and used proper self-medication practices. People with excellent information continued to exhibit logical behaviors while being exposed to medication commercials, which influenced their decision-making.
FORMULASI DAN EVALUASI FISIK SEDIAAN MASKER GEL PEEL OFF DARI HIDROSOL HERBA TIMI (Thymus vulgaris L.) DENGAN VARIASI KONSENTRASI PVA Iin Suhesti; Romanisa Ismawati Qodari; Yuliana Dini Purwanti; Yuni Adellia
Jurnal Farmasindo: Jurnal Penelitian dan Pengabdian Masyarakat Vol. 9 No. 2 (2025): Desember
Publisher : Politeknik Indonusa Surakarta, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.46808/farmasindo.v9i2.299

Abstract

Thyme (Thymus vulgaris L.) is a plant from the Lamiaceae family that contains various active compounds such as saponins, quinones, terpenoids, tannins, and flavonoids. This plant is known to have benefits as a pain reliever, antioxidant, anticancer, antimicrobial, antifungal, liver protector, antidote, anti-inflammatory, and cough suppressant. The purpose of this experiment was to determine the formulation and physical evaluation of the peel-off gel mask preparation from thyme herb hydrosol (Thymus vulgaris L.) with varying concentrations of PVA as a filming agent and its effect on physical evaluations such as organoleptic tests, homogeneity tests, viscosity tests, pH tests, spreadability tests, adhesiveness tests, and drying time tests. The hydrosol used was obtained by distillation. The variations in PVA concentrations used were 10%; 12.5%; and 15%. The results of the study were that it had a cloudy white color, a distinctive odor with a semi-solid, and homogeneous texture. The viscosity values ​​obtained for F1, F2 and F3 were 4335.5 ± 4875.29 cPs; 9749.6 ± 3588.77 cPs; and 7698.07 ± 3818.59 with pH 6.74 ± 0.091; 6.75 ± 0.067; and 6.81 ± 0.035, spreadability 6.21 ± 0.73 cm; 5.57 ± 1.40 and 5.68 ± 0.65, adhesiveness 1.44 ± 0.234 seconds; 10.09 ± 9.754 seconds; and 33.29 ± 14.949 seconds, and drying time 10.165 ± 0.021 minutes; 7.28 ± 0.186 minutes and 5.87 ± 0.693 minutes. Based on the results of the hedonic test using Two Way ANOVA, it was concluded that F2 (PVA 12,5%) was most preferred in terms of color with a value of 3.33; aroma with a value of 3.6 and texture with a value of 2.95.

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