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Obat: Jurnal Riset Ilmu Farmasi dan Kesehatan
Published by Asosiasi Riset Ilmu Kesehatan Indonesia
ISSN : 3031013X     EISSN : 30310148     DOI : 10.61132
Core Subject : Health,
Health Professions Nursing Public Health
Organisasi Farmasi, Kedokteran, Kimia Organik Sintetis, Kimia Alam, Biokimia, Analisis Kimia, Kimia Fisika, Biologi, Mikrobiologi, Jaringan Budaya, Botani dan Hewan terkait Produk Farmasi, Keperawatan, Kebidanan, Analis Kesehatan, Gizi dan Kesehatan Masyarakat.
Arjuna Subject : Profesi Kesehatan - Farmasi
Articles 378 Documents
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Dehydroepiandrosterone Sulfate Deficiencies as Independent Predictors of Increased Coronary Artery Disease in Men with Type II Diabetes Mellitus Mustafa A-Jabbar Al-Jumaili; Abdullah Ali Mohammed; Hawraa M. Alaa Alden; Sura A. Abdulsattar
OBAT: Jurnal Riset Ilmu Farmasi dan Kesehatan Vol. 3 No. 1 (2025): January: OBAT: Jurnal Riset Ilmu Farmasi dan Kesehatan
Publisher : Asosiasi Riset Ilmu Kesehatan Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.61132/obat.v3i1.984

Abstract

The adrenal cortex synthesis the steroid hormone dehydroepiandrosterone (DHEA), has a significant effect on diabetes mellitus. Our study targeted to estimate the relationship between serum levels of DHEA sulphate (DHEAS) and the risk of CAD complication for T2DM in men. Ninety Iraqi male subjects were divided into three groups. Each group has thirty people: thirty people type 2 with diabetes mellitus, thirty person type 2 diabetes mellitus patients with CAD complications, and the control group has thirty healthy people. A significant decrease (p<0.01) of DHEAS, was observed in T2DM with CAD (120.8 µg/dl) compared to both T2DM (141.26 µg/dl) and the control group (239.86 µg/dl). Meanwhile, an increased coronary risk index in T2DM with CAD (10.68) compared to both T2DM (7.56) and control group (4.41) was observed. These findings were confirmed by the negative correlation of DHEAs with coronary risk index. We suggested that a decreased level of DHEAS value may be a beneficial sign for future CAD in patients with T2DM.
Design and Implementation Of A Smart Stick and An Alert Device For People With Visual Impairment Atyaf Ayman Euyz Hashem; Duaa Hassan Hamza Ali; Ruqaya Hassan Abdul Amir Mohammed Saleh; Ahmed Abdel Hadi Mohammed Reda Ali; Tamara Ali Abd Al Ameer Abd Ali
OBAT: Jurnal Riset Ilmu Farmasi dan Kesehatan Vol. 3 No. 1 (2025): January: OBAT: Jurnal Riset Ilmu Farmasi dan Kesehatan
Publisher : Asosiasi Riset Ilmu Kesehatan Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.61132/obat.v3i1.990

Abstract

Electronic cane: It is an electronic cane designed in the shape of a long white cane, but it provides the blind with ultrasonic frequencies that he can feel under his hand and through an audible alarm when it hits a certain obstacle in its path{1}. It can also detect obstacles in all directions at a distance of five meters. The ends of this cane are made of lead. The International Federation of the Blind, which is one of the organizations affiliated with the United Nations, has declared October 15 of each year as the International Day of the White Cane for the Blind, due to the utmost importance of the white cane for the blind, as it makes him depend on himself after God. This dependence is foldable and is stronger and lasts for a long time. It is important to note here that the white cane with a red stripe placed on the lower part of the cane symbolizes the person's suffering from loss of vision with deafness or hearing impairment.  Regardless of the type and shape of the white cane, it has become a symbol of the blind person’s independence and his ability to move, work and integrate into society like other individuals. It guides him to directions, barriers and obstacles and spares him the need to touch things that may be difficult or dangerous to touch, thus protecting him from many harms, in addition to providing him with a lot of information that he lacks due to his lack of sight and the inability of the other senses to provide him with it.
Pengaruh Pemberian Makanan Tambahan Biskuit pada Balita yang Berat Badan Kurang terhadap Peningkatan Berat Badan Balita di Puskesmas Rantau Selamat Aceh Timur Tahun 2024 Dewi Intan Sari; Ester Simanullang
OBAT: Jurnal Riset Ilmu Farmasi dan Kesehatan Vol. 3 No. 1 (2025): January: OBAT: Jurnal Riset Ilmu Farmasi dan Kesehatan
Publisher : Asosiasi Riset Ilmu Kesehatan Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.61132/obat.v3i1.995

Abstract

Providing additional recovery food (PMT), especially for vulnerable groups, is one of the supplementation strategies in overcoming nutritional problems so that cases of malnutrition and malnutrition can be prevented. The aim of this research is to determine the effect of giving supplementary feeding (PMT) biscuits to underweight toddlers on increasing the weight of toddlers at the Rantau Selamat Community Health Center, East Aceh in 2024. This quasi-experimental research uses a one group pre-post test design, namely the existing research design. pretest before being given treatment and posttest after being given treatment. The sample for this research was the entire research population, namely 61 people. Based on the results of this research, the weight status of respondents before the implementation of the PMT program at the Rantau Selamat Community Health Center was underweight for 10 toddlers. The results of the paired T-test statistical test in the second month, the change in toddler's weight before and after PMT-P was shown by the value p=0.000 (p<0.05), so it can be concluded statistically that there is an effect of giving additional food (PMT) on weight status in underweight toddlers (aged 6-33 months). Through this research, it is hoped that it can provide education and increase insight to parents of suffering toddlers to pay more attention to the food intake they consume every day. So that toddlers get adequate nutritional intake in an effort to improve the child's nutritional status.
Hubungan Dukungan Keluarga dengan Kepatuhan Diet Rendah Garam pada Pasien Hipertensi di GB3 Murni Teguh Memorial Hospital Medan Valentino Pardede; Afnijar Wahyu
OBAT: Jurnal Riset Ilmu Farmasi dan Kesehatan Vol. 3 No. 1 (2025): January: OBAT: Jurnal Riset Ilmu Farmasi dan Kesehatan
Publisher : Asosiasi Riset Ilmu Kesehatan Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.61132/obat.v3i1.998

Abstract

Hypertension is a disease that is most commonly suffered by Indonesian people and can occur due to one of the problems that often arises from changes in lifestyle, such as consuming foods with high salt levels, obesity and stress. This study aims to determine the relationship between family support and adherence to a low salt diet in hypertensive patients at GB3 Murmur Memorial Hospital Medan. This research design uses descriptive correlation research with a cross sectional study approach. The data collection technique was carried out using total sampling with a total of 48 patients as respondents. The instrument used to collect data is a questionnaire. From the results of data processing using the Rank Spearman statistical test in SPSS For Windows 27 with a significance level of 95% (α = 0.05), a positive correlation value of 0.375 was obtained and a significant value of 0.009 (p<0.05). The conclusion of this study is that there is a significant relationship between family support and adherence to a low salt diet. For future researchers to make more samples and add independent variables such as knowledge, education, attitudes or motivation, the role of health worker.
Analisis Cemaran Logam Berat (Pb, Cd, Zn) pada Ikan Tuna Kemasan Kaleng dengan Metode Spektrofotometri Serapan Atom (SSA) Tiwi Setianingrum; Adita Silvia Fitriana; Dessy Nawangsari
OBAT: Jurnal Riset Ilmu Farmasi dan Kesehatan Vol. 3 No. 1 (2025): January: OBAT: Jurnal Riset Ilmu Farmasi dan Kesehatan
Publisher : Asosiasi Riset Ilmu Kesehatan Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.61132/obat.v3i1.1007

Abstract

Fish is one type of aquatic product widely used by the community because of its advantages as a food ingredient, including a source of important nutrients such as protein, vitamins, fat, and minerals. Fish is often found in cans. Canned packaging contains the heavy metals lead (Pb), cadmium (Cd), and zinc (Zn), which can be released into food due to the long storage period. This study aims to identify and analyze heavy metals Pb, Cd, and Zn levels in canned tuna with an expiration date of less than 1 year. Samples of canned tuna came from five different brands. Qualitative analysis used color reagents, while quantitative research used an atomic absorption spectrophotometer (AAS). The qualitative study results showed that three samples of tuna contained heavy metals. Samples B and C were positive for Pb metal, while samples A and B were positive for Zn metal. The concentration of Pb metal was measured in sample B at 117.9 mg/Kg and in sample C at -0.0147 mg/Kg. The concentration of Zn metal in sample A was -0.0048 mg/Kg, and in sample B, it was -0.147 mg/Kg.
Formulasi Sediaan Salep Ekstrak Etanol Bawang Putih (Allium Sativum) dengan Variasi Basis Nurhidayah Nurhidayah; Alifa Fitrah
OBAT: Jurnal Riset Ilmu Farmasi dan Kesehatan Vol. 3 No. 1 (2025): January: OBAT: Jurnal Riset Ilmu Farmasi dan Kesehatan
Publisher : Asosiasi Riset Ilmu Kesehatan Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.61132/obat.v3i1.1010

Abstract

Garlic is a medicinal plant that is widely used for health and is used by people for traditional medicine. Garlic contains various secondary metabolite compounds which have antifungal activity, including tannins, flavonoids, allicin. Flavonoids are the largest group of phenolic compounds. So it is possible that flavonoids also have an effective antifungal effect. This research aims to formulate an ethanol extract of garlic (Allium sativum) ointment with a variety of bases and to determine the physical quality of the ointment. The type of research is laboratory experimental. The method used is maceration of the extract using 1000 ml of 70% ethanol, the design of the ointment formulation is to use three base variations FI (Hydrocarbon Base), FII (Absorption Base), FIII (Water Soluble Base). The results of the research conducted show that ethanol extract of garlic (Allium sativum) can be formulated into an ointment and has stable physical quality. The conclusion from this research is that ethanol extract of garlic (Allium sativum) can be formulated into an ointment and has stable physical quality.
Evaluation of Intensive Care Units Nurses' Knowledge regarding Ventilator Associated Pneumonia Prevention in Al-Nasiriya City. Shinjar, Fatima; A. Khasal, Qasim
OBAT: Jurnal Riset Ilmu Farmasi dan Kesehatan Vol. 3 No. 1 (2025): January: OBAT: Jurnal Riset Ilmu Farmasi dan Kesehatan
Publisher : Asosiasi Riset Ilmu Kesehatan Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.61132/obat.v3i1.1015

Abstract

A form of lung infection known as ventilator-associated pneumonia affects patients in hospitals who are on mechanical ventilators. Usually, it influences the cause of rising rates of disease and mortality. Hospital stays for patients with ventilator-acquired pneumonia are longer, and their mortality rate might reach 20–30%. The purpose of the present study was to evaluate the nurses' knowledge concerning preventing of ventilator-associated pneumonia in the intensive care units of Al-Nasiriya City hospitals. Descriptive study was conducted through the present investigation from 31st March, 2020 to 30th of September, 2020. Eighty nurses chosen purposive from intensive care units at AL-Hussein Teaching hospital and Al-Nasiriyah Heart Center. Including (44) females and (36) males. To measure the variables, the researcher constructed a questionnaire. The questionnaire was divided into two sections: demographic information as well as nurses' knowledge about how to prevent ventilator-associated pneumonia. A panel of specialists determined the validity. The data analyzed through descriptive and inferential statistics. The majority of the participants were having poor knowledge about prevention of ventilator associated pneumonia. Non-significant correlation between socio-demographic variables (age, gender, marital status, qualification of nurses, working shift, years of experience in ICU as well as working place) and nurses' Knowledge regarding prevention of ventilator associated pneumonia. New nurses working in ICU should participate in a training program to increase their knowledge of how to prevent ventilator-associated pneumonia. Periodically evaluating as well as for training ICU nurses to increase their understanding of evidence-based practices and nursing interventions for ventilator-associated pneumonia prevention.
Persepsi Pasien Pasca Bedah Mulut (Gusi) terhadap Sisa Makanan Lunak di Rumah Sakit Surya Husadha Denpasar Komang Sugiantari
OBAT: Jurnal Riset Ilmu Farmasi dan Kesehatan Vol. 3 No. 1 (2025): January: OBAT: Jurnal Riset Ilmu Farmasi dan Kesehatan
Publisher : Asosiasi Riset Ilmu Kesehatan Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.61132/obat.v3i1.1017

Abstract

Soft food served in hospitals is a simple indicator that can be used to evaluate the success of hospital nutrition services. The aim of this study was to determine the perception of oral surgery patients regarding soft food waste at Surya Husadha Hospital Denpasar. This research uses a quantitative descriptive survey method. The total population was 30 people, the number of research samples was 20 people... data collection was carried out by measuring perceptions of taste and food waste using a questionnaire for the 20 samples studied. Data was obtained from filling out a questionnaire about perceptions of soft food and a form for the amount of food waste. The data was analyzed using SPSS version 21 statistical analysis. The results of this study showed that there were porridge food waste in 40-49% (45%) of the sample, 50-59% (40%) of the sample, 60-69% (15%) of the sample. Leftover animal side dishes (0%). Vegetable side dishes (10%). Leftover vegetables (10%) And for juice (0%). It can be concluded that the perception of soft food at Surya Husadha Hospital from this research shows that as many as 40-49% (45%) are not satisfied with the rest of the soft food (porridge).
Identifikasi Interaksi Obat pada Resep dengan Diagnosa Gangguan Sistem Endokrin Periode Bulan Juli 2024 di Rumah Sakit X Kota Bandung Salma Tri Octaviany; Tina Rostinawati
OBAT: Jurnal Riset Ilmu Farmasi dan Kesehatan Vol. 3 No. 1 (2025): January: OBAT: Jurnal Riset Ilmu Farmasi dan Kesehatan
Publisher : Asosiasi Riset Ilmu Kesehatan Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.61132/obat.v3i1.1026

Abstract

Drug interactions can occur when drugs are administered simultaneously with other drugs, both pharmacologically and clinically. This study aims to identify drug interactions that occur in prescriptions with patients experiencing endocrine system disorders for the period July 2024 at Hospital X, Bandung City. Endocrine disorders, involving hormonal dysfunction such as that of the thyroid, adrenals, or pancreas, can affect the pharmacokinetics and pharmacodynamics of drugs, thereby increasing the risk of interactions. This research method involved randomly collecting two prescriptions per day, with a total of 60 recipes analyzed. The results of the assessment showed that there were 15 potential drug interactions with a percentage of 25%, consisting of one minor interaction (6.67%), 15 moderate interactions (93.33%), and no major interactions were found.
Effect of Some Types of Anticoagulants on Some Biochemical Parameters of Plasma In Atherosclerosis Disease Abeer Talib. Abdulqader; Muhaned. E. Majeed; Wijdan I. A. Abd-alwahab
OBAT: Jurnal Riset Ilmu Farmasi dan Kesehatan Vol. 3 No. 1 (2025): January: OBAT: Jurnal Riset Ilmu Farmasi dan Kesehatan
Publisher : Asosiasi Riset Ilmu Kesehatan Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.61132/obat.v3i1.1027

Abstract

This study investigated the influence of anticoagulant therapy on biochemical parameters and vascular function in patients with mixed dyslipidemia and asymptomatic atherosclerosis. Twenty-five participants were divided into two groups: a study group (SG) of 15 patients with mixed dyslipidemia and a control group (CG) of 9 healthy individuals. Baseline characteristics, including lipid profiles, inflammatory markers (osteopontin, osteoprotegerin, MMP-2, MMP-9), and clotting parameters, were assessed. The SG exhibited significantly elevated levels of total cholesterol, LDL cholesterol, non-HDL cholesterol, and triglycerides, alongside decreased HDL cholesterol and unexpectedly lower myeloperoxidase levels compared to the CG. Significant variability in biomarker levels was observed across quartiles within both groups. A strong positive correlation was found between serum TSH levels and Factor X activity, while a strong negative correlation was observed between serum TSH and PAI-1 antigen levels in patients with subclinical hyperthyroidism. Clotting times, assessed using the thromboplastin generation test with inosithin, did not reveal significant differences between venous and arterial samples or between the study and control groups based on the provided data. Further research incorporating quantitative clotting time analyses and a more comprehensive assessment of anticoagulant effects is needed to elucidate the complex interplay between anticoagulant therapy, dyslipidemia, and atherosclerosis.

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