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Obat: Jurnal Riset Ilmu Farmasi dan Kesehatan
Published by Asosiasi Riset Ilmu Kesehatan Indonesia
ISSN : 3031013X     EISSN : 30310148     DOI : 10.61132
Core Subject : Health,
Health Professions Nursing Public Health
Organisasi Farmasi, Kedokteran, Kimia Organik Sintetis, Kimia Alam, Biokimia, Analisis Kimia, Kimia Fisika, Biologi, Mikrobiologi, Jaringan Budaya, Botani dan Hewan terkait Produk Farmasi, Keperawatan, Kebidanan, Analis Kesehatan, Gizi dan Kesehatan Masyarakat.
Arjuna Subject : Profesi Kesehatan - Farmasi
Articles 378 Documents
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Gambaran Tingkat Pengetahuan Masyarakat Tentang Dagusibu di Desa Salubomba Kecamatan Banawa Tengah Kabupaten Donggala Ikhsan Hi. Amir Sene; Nurfadilah Nurfadilah
OBAT: Jurnal Riset Ilmu Farmasi dan Kesehatan Vol. 2 No. 1 (2024): Januari : OBAT: Jurnal Riset Ilmu Farmasi dan Kesehatan
Publisher : Asosiasi Riset Ilmu Kesehatan Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.61132/obat.v2i6.791

Abstract

Knowledge results from knowing and occurs when someone senses a particular object. Dagusibu (Get Use Save and Throw Away) is a health education program created by IAI (Indonesian Pharmacists Association) to create a Drug Aware Family Movement as a concrete step to improve the quality of life of the community. This research aims to determine the level of community knowledge about Dagusibu Medicine in Salubomba Village, Central Banawa District, Donggala Regency based on age, occupation, and education. The type of research is descriptive research. The population of the study is all people who live in Salubomba Village, Central Banawa District, Donggala Regency. The sample used was 94 people with each hamlet representing 19 people. The sampling technique uses purposive sampling. The results of the research showed that the level of public knowledge about Dagusibu Medicine in Salubomba Village was 39 respondents with poor knowledge, 51 respondents with sufficient knowledge, and 4 respondents with good knowledge. So, it can be concluded that the level of knowledge of the people in Salubomba Village has an adequate level of knowledge about Dagusibu Medicine. The conclusion that can be drawn is that the level of public knowledge about Dagusibu Medicine is sufficient knowledge, namely the level of public knowledge based on age level with less knowledge is 41.42%, based on occupation, less knowledge is 41.42%, and based on education, less knowledgeable is 41.48%.
Peran Harapan dalam Kepatuhan Pengobatan Kanker Kolorektal M. Agung Rahmadi; Helsa Nasution; Luthfiah Mawa; Romaito Nasution; Milna Sari
OBAT: Jurnal Riset Ilmu Farmasi dan Kesehatan Vol. 2 No. 6 (2024): November : OBAT: Jurnal Riset Ilmu Farmasi dan Kesehatan
Publisher : Asosiasi Riset Ilmu Kesehatan Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.61132/obat.v2i6.793

Abstract

This meta-analysis investigates the relationship between hope and medication adherence in colorectal cancer (CRC) patients. Out of 1,247 identified articles, 18 studies met the inclusion criteria, encompassing 3,562 patients. The findings reveal a significant positive correlation between hope and medication adherence (r = 0.42, 95% CI: 0.35-0.49, p < 0.001), with notable heterogeneity (I² = 76.4%, Q = 72.03, df = 17, p < 0.001). Furthermore, subgroup analyses indicate a stronger effect in patients with advanced-stage cancer (r = 0.49, 95% CI: 0.39-0.58) compared to those in various earlier stages (r = 0.38, 95% CI: 0.30-0.46, Q = 4.12, df = 1, p = 0.04). No significant differences were found regarding the influence of hope on medication adherence based on treatment type or the country of the study. Additionally, this research extends the findings of DiMatteo et al. (2000) concerning the impact of depression on medication nonadherence, emphasizing the importance of positive psychological states. Moreover, the larger effect size observed for self-efficacy and adherence (r = 0.31) reported by Hall et al. (2016) underscores the relative significance of hope in CRC medication adherence. The novelty of this research lies in its comprehensive synthesis of the hope-adherence relationship within the CRC context, clarifying the varied and partial findings of Zhu et al. (2017) and García-Torres et al. (2016). Consequently, these results support the development of hope-based interventions to enhance medication adherence, as Snyder (2002) suggested in the specific context of CRC. Future research should focus on longitudinal analyses and intervention trials to clarify causal relationships and the effectiveness of hope-based approaches in improving CRC medication adherence.
Hubungan Fungsi Kepala Ruangan dengan Kinerja Perawat Pelaksana di Ruangan Rawat Inap RSUD Palangka Raya Noor Hidayati; Karmitasari Yanra Katimenta; Henry Wiyono
OBAT: Jurnal Riset Ilmu Farmasi dan Kesehatan Vol. 2 No. 6 (2024): November : OBAT: Jurnal Riset Ilmu Farmasi dan Kesehatan
Publisher : Asosiasi Riset Ilmu Kesehatan Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.61132/obat.v2i6.798

Abstract

One of the critical elements affecting nurse performance and impacting the quality of nursing services is the implementation of the head nurse's functions. This role must be effectively integrated into the healthcare system to motivate nurses to provide optimal patient care, thereby improving community health quality. This study aims to analyze the relationship between the head nurse's functions and the performance of bedside nurses in the inpatient wards at RSUD Palangka Raya. Method: This study employed a quantitative method with a correlational research type and a cross-sectional approach. The sampling technique used was total sampling, involving 34 respondents. Data collection was performed using a questionnaire, and statistical analysis was conducted using the Spearman Rank Correlation test. Results:The results of the Spearman Rank statistical test showed a significance value (2-tailed) of p = 0.00 with a level of significance of p < 0.05, indicating a relationship between the head nurse's functions and the performance of bedside nurses. The correlation coefficient was 0.685, reflecting a high or strong correlation. This positive relationship indicates that as the function of the head nurse improves, the performance of bedside nurses also increases. Therefore, the alternative hypothesis (Ha) is accepted, meaning there is a relationship between the head nurse's functions and the performance of bedside nurses. Conclusion: There is a significant relationship between the head nurse's functions and the performance of bedside nurses. It is recommended that the hospital provide training for head nurses on management functions.
Hubungan Pengetahuan dengan Peran Kader Posyandu Balita dalam Capaian Imunisasi Dasar Lengkap di Wilayah Kerja Puskesmas Bahaur Hilir Kabupaten Pulang Pisau Angga Renaldi; Karmitasari Yanra Katimenta; Henry Wiyono
OBAT: Jurnal Riset Ilmu Farmasi dan Kesehatan Vol. 2 No. 6 (2024): November : OBAT: Jurnal Riset Ilmu Farmasi dan Kesehatan
Publisher : Asosiasi Riset Ilmu Kesehatan Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.61132/obat.v2i6.799

Abstract

Knowledge and the role of posyandu (integrated service post) cadres are crucial and strategically important in providing health education to the community. According to 2023 data, the coverage of complete basic immunization at posyandu is significantly below the target. Surveys revealed that some cadres have insufficient knowledge and a minimal role in immunization services, such as providing counseling, encouraging, and motivating mothers to immunize their children. This study aims to determine the relationship between knowledge and the role of posyandu cadres in achieving complete basic immunization in the working area of Puskesmas Bahaur Hilir, Pulang Pisau District. Method: This research is a correlational study with a quantitative method using a cross-sectional approach. The sampling technique employed was total sampling, with 65 respondents. Data were collected using a questionnaire, and statistical analysis was performed using the Spearman correlation test. Results: The data analysis revealed a significant relationship between knowledge and the role of cadres, with a significance value (p-value) of 0.000 < 0.05 and a strong correlation coefficient of 0.642. Conclusion: There is a significant relationship between knowledge and the role of cadres, with a strong correlation coefficient. It is recommended that posyandu cadres enhance their knowledge and active participation in posyandu activities and communicate information to the community to improve health outcomes.
Manajemen Rhinitis Alergi Salsabila Dwi Irga Syarif; Mukhlis Imanto; Septia Eva Lusiana
OBAT: Jurnal Riset Ilmu Farmasi dan Kesehatan Vol. 2 No. 6 (2024): November : OBAT: Jurnal Riset Ilmu Farmasi dan Kesehatan
Publisher : Asosiasi Riset Ilmu Kesehatan Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.61132/obat.v2i6.800

Abstract

Allergic rhinitis (AR) is an atopic disease characterized by symptoms of nasal congestion, clear rhinorrhea, sneezing, postnasal drop, and nasal pruritis. The disease affects one in six people and is associated with significant morbidity, loss of productivity, and health care costs. Historically, AR was considered a disease process in the nasal airways only, although it is not serious, allergic rhinitis should be considered as a quite serious condition because it can affect the sufferer's quality of life due to the severity of the symptoms experienced and can also cause various complications. However, the development of integrated airway theory has classified AR as a component of the systemic allergic response, with other related conditions, such as asthma and atopic dermatitis, having an underlying systemic pathology. Even though it is not serious, allergic rhinitis should be considered as a quite serious condition because it can affect the sufferer's quality of life due to the severity of the symptoms experienced and can also cause various complications. In addition to nasal symptoms, patients with AR may also experience allergic conjunctivitis, non-productive cough, Eustachian tube dysfunction, and chronic sinusitis. Once diagnosed, AR can be treated in a variety of ways, with intranasal glucocorticoids being the first line of therapy.
Analisis Manajemen Logistik Obat di Dinas Kesehatan Kabupaten Kolaka Tahun 2023 Adewiah Sari; Nani Yuniar; Renni Meilahsari
OBAT: Jurnal Riset Ilmu Farmasi dan Kesehatan Vol. 2 No. 6 (2024): November : OBAT: Jurnal Riset Ilmu Farmasi dan Kesehatan
Publisher : Asosiasi Riset Ilmu Kesehatan Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.61132/obat.v2i6.802

Abstract

Good logistics management of medicines is one of the factors so that medicines can be managed well. The pharmacy unit of the Kolaka District Health Service has problems with inadequate storage or storage of medicines and delays in the arrival of medicines. The aim of this research is to determine the Analysis of Drug Logistics Management at the Kolaka District Health Service. The research uses qualitative methods through in-depth interviews, observations and observation guides. The results of the research show that at the drug planning stage using the consumption method, drug procurement using an e-catalog system, drug storage is still not good because the warehouse is not large enough for drug storage. Suggestions for the Kolaka District Health Service.
Efek Pemberian Campuran Madu Terhadap Peningkatan Kadar Hemoglobin Pada Ibu Hamil Dengan Anemia Endry Sulistyowati; Sri Mintarsih; Sulastri Sulastri; Hanantya Henry Setyabudi
OBAT: Jurnal Riset Ilmu Farmasi dan Kesehatan Vol. 1 No. 6 (2023): November : OBAT: Jurnal Riset Ilmu Farmasi dan Kesehatan
Publisher : Asosiasi Riset Ilmu Kesehatan Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.61132/obat.v1i6.806

Abstract

Background: Anemia in pregnant women can increase the risk of premature birth, maternal and child mortality, and infectious diseases. According to WHO, the prevalence of anemia in pregnant women is around 35-75%, and it increases with the growth of gestational age. Objective: This study aims to increase insight and knowledge and to find out the incidence of pregnant women with anemia before and after the intervention. In addition, to analyze the effect of giving a mixture of honey to increase hemoglobin levels in anemic pregnant women. Methods: The design in this study used the Quasi-experimental design method. Quasi-experimental design (quasi-experimental) with a quantitative approach to one group design pre-test and post-test. The population in this study were all pregnant women who came to check their pregnancy at the Pratama Hidayah Clinic in January 2022. The sampling technique in this study was purposive sampling, namely taking samples based on considerations with the desired elements by inclusion criteria with the number of a sample of 15 respondents. Results: Test using the Shapiro Wilk method. The significance value of the pre-test variable is 0.994 and the significance value of the post-test variable is 0.153 or > 0.050, meaning that the data in this study are normally distributed. So the statistical test used is the T-test with a p-value of pre-test - post test of 0.000 < 0.050. Thus, it can be concluded that there is a significant difference between the average pre-test and post-test variables. This means that there is an effect of giving a mixture of honey increases hemoglobin levels in pregnant women with anemia. Conclusion: From the research conducted that there is a significant difference between the value of the pre-test and post-test, besides that there is a very strong relationship between the effect of giving a mixture of honey to the increase in hemoglobin levels in the mother. pregnant with anemia.
Synthesis and Characterization of Novel Bis-Schiff Bases Based O-Tolidine Mustafa A-Jabbar Al-Jumaili
OBAT: Jurnal Riset Ilmu Farmasi dan Kesehatan Vol. 2 No. 6 (2024): November : OBAT: Jurnal Riset Ilmu Farmasi dan Kesehatan
Publisher : Asosiasi Riset Ilmu Kesehatan Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.61132/obat.v2i6.828

Abstract

Three novel Schiff base (A-C) was reported in this study by reaction of o-tolidine with three different aldehydes 2-bromobenzaldehyde, 3-hydroxybenzaldehyde, and 2,4-dihydroxybenzaldehyde to attain three novel Bis-Schiff Bases ligands in high yield (86-97%). Thin-layer chromatography (TLC) technique is used to monitor the reaction. These agents were characterized by 13C, 1H NMR, HRMS, FTIR, and melting point. The synthesized tcompounds (A-C) are expected to have considerable biological activity owing to their molecular structure, which incorporates essential imine functional groups.
Prevalence of Toxoplasmosis Seropositive Antibodies among Children with Autistic Spectrum Disorders (ASD) Omar Ibrahim, Razaw; Abdul-Kareem Khidhir Abbas
OBAT: Jurnal Riset Ilmu Farmasi dan Kesehatan Vol. 3 No. 1 (2025): January: OBAT: Jurnal Riset Ilmu Farmasi dan Kesehatan
Publisher : Asosiasi Riset Ilmu Kesehatan Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.61132/obat.v3i1.972

Abstract

Toxoplasma gondi is a pervasive parasite that causes a variety of diseases both in humans and animals, it infects the neural cells of the central nervous system. There have been previous reports linking this infection with Autism. Autism is a combination of complex neurodevelopmental disorders leading to alteration in social communication. This study was done to detect the frequency of seropositive Toxoplasmosis in Autistic children attending psychiatric units in Azady Teaching Hospital in Kirkuk governorate-Iraq. This case-control study was done on 40 Autistic children (30 male, 10 female) with an average age of 5.4±6 years and 40 healthy children (8 male, 32 female) with the same age range (6.1±2) year, from April 2018- January 2020. Sample collection was done by obtaining four ml of blood from all study group children for the detection of both IgM and IgG Toxoplasma gondi antibodies using the ELISA technique. Chi-square and paired T-tests were used for data analysis. The IgM serology for both Autistic and control children was negative while there was just one positive result of T.gondi IgG in Autistic Children and two positive results in normal children which made the result insignificant( X2=0.45, p-value>0.05). Regarding gender, there was no significant difference in detecting positive results between boys and girls of the study groups (X2=0.45 p value> 0.05). The study also demonstrated that Autistic Parents were statistically older than healthy children of the same age. We couldn't uncover any connection between ASD and toxoplasmosis. The age of parents & family history has a significant impact on the development of ASD.
Bacterial Infection Associated with Respiratory Cystic Fibrosis in Al-Hilla City Rawaa M. Mohammed
OBAT: Jurnal Riset Ilmu Farmasi dan Kesehatan Vol. 3 No. 1 (2025): January: OBAT: Jurnal Riset Ilmu Farmasi dan Kesehatan
Publisher : Asosiasi Riset Ilmu Kesehatan Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.61132/obat.v3i1.979

Abstract

Back ground: Autosomal genetic diseases throughout North America are propagated by CF, which is seen in 1 out of 2000 Caucasians. This sickness can in most cases be undetected and is nongendered with a global impact and targets all ages. By the impaired mucocilliary clearance in the trachea and bronchi, and the inability to maintain innate defenses, acute and recurrent bacterial infections, airways obstruction and inflammation and chronic bacterial infections are aggravated. Aim of study: The study aims to isolate and identify bacterial species related to respiratory fibrosis and to do the susceptibility test to those species. Methodology: The study was carried out between January-July 2024, 80 cystic fibrosis patients admitted in Mirjan hospital, 50 came outpatients clinic and 30 found sleeping in the hospital (Eighteen in the respiratory lobbies and 12 in the intensive care unit (ICU)), patient age range between 20-80 years old, and include both gender, 28 females and 52 male.es). By using sterile labeled machines every patient provide sputum that was transported to laboratory directly after collection and stored in 4 C temperatures until culture. All samples of sputum were cultivated for twenty-four hours at 37 degrees Celsius in an incubator utilizing MAConkey and Blood agars. Thereafter, samples were streaked unto several selective and differential media where bacterial colonies matured to reveal their biochemical characteristic after 24hrs of incubation. Results: The current study's results indicated that age has an impact on microbial CF infection. Of the 80 total patients, 9 sample in the age group of 20–30 years had a percentage of 11.25%, while 11 patients in the age group of 31–40 years had a percentage of 13.75%, 16 patients in the age group of 41–50 years had a percentage of 16.25%, and 17 patients in the age group of 51–60 years had a percentage of 21.25%. The current study confirmed that infection rates increase with age. In terms of gender, the study show that males are more likely than females to get infections. with 52 males in the (65%) percentage and 28 females in the (35%), Ten patients are in the 71–80 age range, and twenty patients are in the 61–70 age group. Conclusion: The kind of bacterial strain, the patient's immunological condition, and the usage of contaminated medical equipments are some of the factors that affect transmission. During treatment, all CF patients colonized or infected with the primary pathogens discussed in this article must be kept in a single room to prevent nosocomial dissemination of the microorganism to other patients. Despite the intricacy of the epidemiology of bacterial infections in CF patients, the average lifespan of these individuals continues to increase.

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