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Obat: Jurnal Riset Ilmu Farmasi dan Kesehatan
Published by Asosiasi Riset Ilmu Kesehatan Indonesia
ISSN : 3031013X     EISSN : 30310148     DOI : 10.61132
Core Subject : Health,
Health Professions Nursing Public Health
Organisasi Farmasi, Kedokteran, Kimia Organik Sintetis, Kimia Alam, Biokimia, Analisis Kimia, Kimia Fisika, Biologi, Mikrobiologi, Jaringan Budaya, Botani dan Hewan terkait Produk Farmasi, Keperawatan, Kebidanan, Analis Kesehatan, Gizi dan Kesehatan Masyarakat.
Arjuna Subject : Profesi Kesehatan - Farmasi
Articles 378 Documents
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Review Artikel: Evaluasi Efektivitas Berbagai Macam Metode Sterilisasi Herta Meidya Nurhalita; Alfi Dwi Seviah; Kurrota Ayyun; Laila Sabila Sindriyani; Yeka Khafidz Ila Rosyidah; Dewi Rahmawati; Dzakiah Zhirotul Wida; Fitrul Mubarok
OBAT: Jurnal Riset Ilmu Farmasi dan Kesehatan Vol. 3 No. 1 (2025): January: OBAT: Jurnal Riset Ilmu Farmasi dan Kesehatan
Publisher : Asosiasi Riset Ilmu Kesehatan Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.61132/obat.v3i1.1029

Abstract

Sterilization is a process that aims to remove all forms of microbial life, including bacteria, viruses, fungi, and spores, from an object or surface. This process is very important in various fields, such as medicine, laboratories, food industry, and pharmaceuticals, to prevent infection and contamination. This article was written through a literature review of articles originating from international and national journals. Data searches were carried out through scientific-based websites and databases, namely Google Scholar, Science Direct, and PubMed. The results show that of various sterilization methods such as autoclave, oven, ozone, filtration, steam, 70% alcohol, UV radiation and gamma rays, each has different effectiveness in killing microorganisms, and each method has advantages and disadvantages. . The conclusion of this article provides a comprehensive evaluation of the effectiveness of various sterilization methods used in laboratory and industrial contexts. Various techniques, such as autoclave, oven, ozone, filtration, steam, 70% alcohol, UV radiation and gamma rays.
Perumusan Corrective Action and Preventive Action (CAPA) pada Salah Satu Pedagang Besar Farmasi di Kota Bandung Ella Fazila; Norisca Aliza Putriana
OBAT: Jurnal Riset Ilmu Farmasi dan Kesehatan Vol. 3 No. 1 (2025): January: OBAT: Jurnal Riset Ilmu Farmasi dan Kesehatan
Publisher : Asosiasi Riset Ilmu Kesehatan Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.61132/obat.v3i1.1030

Abstract

Pharmaceutical Wholesalers or commonly known as PBFs are companies in the form of legal entities that have permits to procure, store and distribute large quantities of pharmaceutical supplies in accordance with the provisions of applicable laws and regulations. PBF must implement a quality system that includes quality risk management principles. An effective quality management system must include a Corrective Action and Preventive Action (CAPA) process to address deviations and prevent the same problems from occurring again in the future. The research was carried out by reviewing cases found by the Center for Food and Drug Monitoring (BBPOM) at PBF "X" and then continuing with an analysis of corrective actions and corrective actions that needed to be taken to overcome these cases of deviation. The results of the research show that the preparation of the CAPA by PBF PBF “X” has implemented most of the provisions contained in the CDOB guidelines well.
Penetapan Kadar Kalsium Laktat dengan Menggunakan Metode Titrasi Kompleksometri Nur Khadijah Anasyah; Nurfadillah Nurfadillah; Dian Fadillah; Rini Ariyanti; Musfirah Musfirah; Putri Indah Ramadhani; Amri Alwi; Yuniarsyah Yuniarsyah; Rismawati Kalean; Sulfiana Sulfiana; Yuyun Sri Wahyuni; Masyhuri Muhaimin; Haryanto Haryanto
OBAT: Jurnal Riset Ilmu Farmasi dan Kesehatan Vol. 3 No. 1 (2025): January: OBAT: Jurnal Riset Ilmu Farmasi dan Kesehatan
Publisher : Asosiasi Riset Ilmu Kesehatan Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.61132/obat.v3i1.1033

Abstract

This research aims to determine calcium lactate levels using the complexometric titration method, which involves the formation of a complex between metal ions and ligands, specifically using EDTA (Ethylenediaminetetraacetate) as a titrant. The sample was dissolved in distilled water, the murexide indicator was added, and titrated with complexon III solution until the color changed from orange to violet as a marker for the end point of the titration. Data analysis shows that the percentage of calcium lactate levels in replication (1) is 93.32%, replication (2) 101.60%, replication (3) 95.93%, replication (4) 103.78%, replication (5) 109.02%, replication (6) 87.87%, replication (7) 95.93% and replication (8) 100.95%, and the percentage obtained the average purity is 98.55%. However, replications 5 and 6 did not comply with the standards of the Indonesian Pharmacopoeia VI edition (94.0–106.0%). This research shows that the complexometric titration method is effective in determining calcium lactate levels with good accuracy, as long as it is carried out with appropriate procedures and strict control of the analysis conditions.
Artikel Review: Formulasi Sediaan Tetes Mata untuk Mata Kering Dewi Rahmawati; Tiara Putri Hartanto; Miftahul Maulidiyah; Silvia Nur Diana Putri; Cantika Putri Amanda; Rizma Salsa Salim; Chindy Elsa Ramadhani; Dzakiah Zhirotul Wida; Fitrul Mubarok
OBAT: Jurnal Riset Ilmu Farmasi dan Kesehatan Vol. 3 No. 1 (2025): January: OBAT: Jurnal Riset Ilmu Farmasi dan Kesehatan
Publisher : Asosiasi Riset Ilmu Kesehatan Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.61132/obat.v3i1.1036

Abstract

Eye drops are used for dry eyes, red eyes, allergies, infections, and glaucoma. Evaluation of eye drops includes pH, osmolality, and viscosity, which must be adjusted so that the preparation is comfortable for the eyes and does not cause irritation. This review aims to determine the active ingredients that are suitable for use and the efficacy of these active ingredients in eye drops that are made. Literature searches were conducted using online-based literature search instruments, such as Google Scholar. The results and discussions include several physical and chemical evaluations from several journals. Based on the literature study conducted, it can be concluded that various formulation innovations for the treatment of dry eyes, including lipid-based liposomes, omega-3 fatty acids, and natural ingredients such as castor oil, show great potential in mimicking the function of the natural tear film, reducing fluid evaporation, and supporting regeneration and stability of corneal epithelial cells.
Artikel Review : Pengaruh Edukasi Terhadap Manajemen Diri Pasien Diabetes Mellitus (DM) Alfi Dwi Seviah; Fitria Ayu Kusumaningtyas; Nabyla Qutrun Nada; Amelia Saputri Ginting; Natalia Abuk Bria; Alfu Laila; Bella Fevi Aristia; Eka Putri Nurhidayah
OBAT: Jurnal Riset Ilmu Farmasi dan Kesehatan Vol. 3 No. 1 (2025): January: OBAT: Jurnal Riset Ilmu Farmasi dan Kesehatan
Publisher : Asosiasi Riset Ilmu Kesehatan Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.61132/obat.v3i1.1041

Abstract

Diabetes Mellitus (DM) is a global health problem that continues to increase, especially in Indonesia. This disease is characterized by high blood glucose levels due to impaired insulin metabolism. This article aims to evaluate the effect of pharmaceutical education, particularly through booklets, pocket books, and counseling, on the self-management of type 2 DM patients. The results of the study show that pharmaceutical education is significant in improving patients' knowledge, compliance, and quality of life. Education through booklets and pharmacy counseling helps patients understand the importance of managing diet and physical activity. Although education has been shown to improve control of blood glucose levels, many patients still face challenges in consistently implementing self-management. Therefore, a more integrated and sustainable educational approach is needed to support DM patients in managing their condition effectively.
Efektivitas Intervensi Non-Farmakologis sebagai Upaya Menghentikan Kebiasaan Merokok Safanda Tiara Fitri; Rizki Amalia Putri; Miftahul Maulidiyah; Novita Dewi; Rizma Salsa Salim; Dewi Nur Halisa; Bella Fevi Aristia; Alfulaila Alfulaila; Eka Putri Nurhidayah
OBAT: Jurnal Riset Ilmu Farmasi dan Kesehatan Vol. 3 No. 1 (2025): January: OBAT: Jurnal Riset Ilmu Farmasi dan Kesehatan
Publisher : Asosiasi Riset Ilmu Kesehatan Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.61132/obat.v3i1.1054

Abstract

Smoking is one of the leading causes of morbidity, premature death, and disability that can be prevented by various efforts. This article reviews various non-pharmacological interventions that are effective in reducing smoking behavior. The method used is to conduct a literature search from 10 journals. The results of the article review show that all methods used to stop smoking behavior have proven effective. The methods for stopping smoking that are widely used in this article are SFET, MHT, Making xylitol candy and nicotine candy, and counseling on efforts to reduce smoking cessation. This method can reduce the intensity of smoking and increase awareness of the dangers of smoking. In addition, the use of xylitol gum and education programs have also been shown to be effective in reducing smoking habits. An approach that involves family and community support, as well as appropriate counseling, is very important to increase individual knowledge and motivation to quit smoking. With the right combination of strategies, it is expected to reduce the prevalence of smoking and its negative impacts on public health.  
Karakteristik Senyawa Kimia Ekstrak Ikan Gabus (Channa striata) dari Danau Tondano Menggunakan Fourier Transform Infra Red (FTIR) Sangkal Ahlan; Supardi Rifani Hutami
OBAT: Jurnal Riset Ilmu Farmasi dan Kesehatan Vol. 3 No. 1 (2025): January: OBAT: Jurnal Riset Ilmu Farmasi dan Kesehatan
Publisher : Asosiasi Riset Ilmu Kesehatan Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.61132/obat.v3i1.1056

Abstract

Snakehead fish (Channa striata) is a freshwater fish that is widely found in Indonesia. Snakehead fish has many benefits, including increasing albumin levels in the blood, increasing endurance, can heal wounds, both internal wounds, external wounds and post-operative wounds. The purpose of this study was to determine the character of the chemical compounds of snakehead fish extract in Lake Tondano. The method used for extraction is the Steaming method and analyzed using FTIR. The results of the study of Snakehead fish extract were analyzed in the FTIR computer application and obtained results showing 11 absorption band peaks. At the absorption band peaks of 3626.34 cm-1 and 3445.20 cm-1 indicate the O-H group suspected of having an alcohol compound. At the absorption band peak of 2097.19 cm-1 indicates the C = C group suspected of having an alkene compound. The peak of absorption band 1651.21 cm-1 and 1644.98 cm-1 indicates C=O group which is suspected to be amide compound I. The absorption band 1551.19 cm-1 indicates bending vibration of N-H group and stretching vibration of C-N which is suspected to be amide compound II. The absorption band 1458.33 cm-1 indicates CH3 group in the presence of collagen. The absorption band 1400.04 cm-1 indicates COO group which is suspected to be amino acid compound, aspartic acid and glutamic acid. The absorption band 1080.74 cm-1 indicates C-N group which is suspected to be amine compound. And the last absorption band is 562.15 cm-1 and 494.05 cm-1 indicates stretching vibration which indicates other compounds
Formulasi dan Evaluasi Sediaan Granul Effervescent Ekstrak Kulit Buah Sukun (Artocarpus altilis) Djamal Julia Megawati; Muh Hidayat; Miftahurrahmah Pansariang
OBAT: Jurnal Riset Ilmu Farmasi dan Kesehatan Vol. 3 No. 1 (2025): January: OBAT: Jurnal Riset Ilmu Farmasi dan Kesehatan
Publisher : Asosiasi Riset Ilmu Kesehatan Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.61132/obat.v3i1.1057

Abstract

Breadfruit (Artocarpus altilis) is a kind of consumable plant, generally peoples will process the fruit and discharge the peel. Effervescent granule is a practice of powder preparation. This study aim to create the effervescent granulation preparation to making the peel if breadfruit will easier to consumen with extract concentrations : F1 (5%), F2 (10%), and F3 (15%) and determine the characteristics of the resulting preparation. Making effervescent granules using the alkaline granulation method. Then the resulting preparation is evaluated by testing, including organoleptic test, pH, flow rate, angle of repose, dissolve time, water content, granule size distribution, and froth height. Breadfruit peel extract can be formulated into effervescent granule preparations. Effervescent granules of F1, F2, and F3 from breadfruit peel extract produce a brownish-white powder, characteristic of the extract. All of the formulas have qualified pH, water content, rest angle, dissolve time, and granule size. Flow velocity F1 7.99 g/sec and F2 7.21 g/sec, including flow velocity "good,” while F3 includes “poorly soluble’ 2.68 g/sec. However, the formulas do not meet the foam height requirements in the market with a foam height of 3 cm, where FI is 0.9 cm, F2 is 0.93 cm, and F3 is 0.96 cm.
Skrining Fitokimia dan Uji Kualitatif Aktivitas Antioksidan Ekstrak Etanol Daun Ketepeng Cina (Cassia Alata L) dengan Metode DPPH Husen Ernawati; Supardi Rifani Hutami; Mantali M. Fathurrachman
OBAT: Jurnal Riset Ilmu Farmasi dan Kesehatan Vol. 3 No. 2 (2025): March: OBAT: Jurnal Riset Ilmu Farmasi dan Kesehatan
Publisher : Asosiasi Riset Ilmu Kesehatan Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.61132/obat.v3i2.1068

Abstract

Cassia alata L or generally knowles as Chinese leaves contain phytochemical compounds, one of which is flavonoids which have the potential as antioxidants, antioxidants can be used to prevent diseases with oxidative stress. The purpose of this study was to determine the content of phytochemical screening and qualitative testing of antioxidant activity ethanol ekstract of Chinese leaves (Cassia alata L) using the DPPH method. This study is a qualitative study with an extraction process using the maceration method with 96% ethanol solvent. Phytochemical screening and antioxidant activity testing were carried out by adding specific reagents. The results of phytochemical screening and antioxidant activity testing of Chinese leaves (cassia alata L) ekstract contain bioactive compounds such as flavonoids, saponins, tannins and antioxidant activity testing with DPPH reagents showed that Chinese leaves (cassia alata L) extract has antioxidant activity which is indicated by a change of the color from purple to yellow. From the results obtained, it can be concluded that the flavonoid compound content in Chinese leaves (cassia alata L) extract can potentially act as an antioxidant.
Aktivitas Farmakologi Senyawa Aktif yang Diisolasi dari Tumbuhan Obat Alifia Hasna Hamidah; Tiana Milanda
OBAT: Jurnal Riset Ilmu Farmasi dan Kesehatan Vol. 3 No. 1 (2025): January: OBAT: Jurnal Riset Ilmu Farmasi dan Kesehatan
Publisher : Asosiasi Riset Ilmu Kesehatan Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.61132/obat.v3i1.1070

Abstract

Traditional medicine is currently developing rapidly, especially those based on plants. Active plant compounds are the main basis for the development of new drugs, which after further research, can be commercialized and used in pharmaceutical treatment. This review was conducted to identify the pharmacological effects of active drug compounds isolated from medicinal plants by conducting a literature study. The results of the literature review contained 37 articles that met the inclusion criteria. Until now, there are several active drug compounds from plants that are sold commercially in the form of modern drugs. Some of the pharmacological effects found are cardiac glycosides, anticholinergics, antiplatelets, analgesics, anticancer, sympathomimetics and antimalarials. This search shows that natural materials are still used as a potential source of active drug compounds, thus encouraging research to find new active compounds from medicinal plants to overcome diseases in the future.

Page 18 of 38 | Total Record : 378

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