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Obat: Jurnal Riset Ilmu Farmasi dan Kesehatan
Published by Asosiasi Riset Ilmu Kesehatan Indonesia
ISSN : 3031013X     EISSN : 30310148     DOI : 10.61132
Core Subject : Health,
Health Professions Nursing Public Health
Organisasi Farmasi, Kedokteran, Kimia Organik Sintetis, Kimia Alam, Biokimia, Analisis Kimia, Kimia Fisika, Biologi, Mikrobiologi, Jaringan Budaya, Botani dan Hewan terkait Produk Farmasi, Keperawatan, Kebidanan, Analis Kesehatan, Gizi dan Kesehatan Masyarakat.
Arjuna Subject : Profesi Kesehatan - Farmasi
Articles 378 Documents
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Water Microbial Contamination in Tikrit City Aya Jameel Rasheed; Sarah Abdulhameed Hasan; Saba AbdulKareem Mustafa
OBAT: Jurnal Riset Ilmu Farmasi dan Kesehatan Vol. 2 No. 5 (2024): September : OBAT: Jurnal Riset Ilmu Farmasi dan Kesehatan
Publisher : Asosiasi Riset Ilmu Kesehatan Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.61132/obat.v2i5.698

Abstract

In the world consequently, pollution of water has become a great concern, and with emphasis on the quality of water especially on those which originate from natural sources, with regard to water borne diseases and their causing pathogens. Some of the more familiar water borne pathogens include: aquatic or enteric bacteria such as Salmonella typhi, Shigella, Coliform bacteria; viruses; and Protozoa. Also relevant to diarrhea are rotavirus, astrovirus, adenovirus, norovirus, picobirnavirus, and enterovirus. This research work was done on a cross-sectional study basis over a period of four months, from April to October of the year 2022 at various water supply stations in Tikrit City, Salah Al-Deen province. Grab samples were taken from both the wells and the Tigris River to carry out microbiological processing and quality check in the laboratory. The samples used in this study included river and well water sources taken at the water treatment centers. Samples were collected at three points in the Tigris River and at three points from wells, although the points varied across the different sites. The findings were mainly secular for E. coli followed by P. aeruginosa and parasite such as Giardia cysts, and amoebic cysts.
Tingkat Kepuasan Pengunjung Apotek Terhadap Pelayanan Kefarmasian di Beberapa Apotek Kabupaten Karanganyar Novia Amalia; Rolando Rahardjoputro; Adhi Wardhana Amrullah
OBAT: Jurnal Riset Ilmu Farmasi dan Kesehatan Vol. 2 No. 5 (2024): September : OBAT: Jurnal Riset Ilmu Farmasi dan Kesehatan
Publisher : Asosiasi Riset Ilmu Kesehatan Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.61132/obat.v2i5.702

Abstract

Health is a pivotal factor in enhancing human quality of life by improving healthcare service quality. Pharmacies serve as crucial healthcare facilities widely frequented by the populace. High-quality pharmaceutical services in pharmacies can gratify patients, foster patient loyalty, and augment patient quality of life. This study aims to ascertain patient satisfaction levels regarding pharmaceutical services at several pharmacies in Karanganyar Regency. This descriptive observational study employed a quantitative approach. Sampling was conducted using non-probability sampling with an accidental sampling technique, resulting in a sample of 105 respondents. Patient satisfaction levels were computed using SPSS Statistics 25. Research findings revealed satisfaction rates for pharmacy service indicators: pharmacy appearance achieved 85.10% (very satisfied), staff friendliness achieved 80.23% (very satisfied), medication information provision achieved 82.66% (very satisfied), medication availability achieved 83.27% (very satisfied), and service speed achieved 87.93% (very satisfied). In conclusion, patients expressed overall satisfaction with pharmaceutical services at several pharmacies in Karanganyar Regency.
Penerapan Kompres Daun Kol terhadap Pembengkakan Payudara Pada Ibu Post Partum di Kecamatan Karangdowo Siti Erlinawati; Mulyaningsih Mulyaningsih
OBAT: Jurnal Riset Ilmu Farmasi dan Kesehatan Vol. 2 No. 5 (2024): September : OBAT: Jurnal Riset Ilmu Farmasi dan Kesehatan
Publisher : Asosiasi Riset Ilmu Kesehatan Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.61132/obat.v2i5.706

Abstract

Breast swelling in post partum mothers if not immediately resolved will cause mastitis and breast abscess. There are 32.6% of infants in Jawa Tengah who have not met exclusive breastfeeding with the main factor due to breast swelling. One of the non-pharmacological therapies used is cabbage leaf compress. This study describes the comparison of the development of breast swelling scale before and after the application of cabbage leaf compress. This research uses a case study of 2 respondents carried out for 3 consecutive days in the morning and evening with a duration of 15-20 minutes. the application of cabbage leaf compresses on both respondents obtained comparative results, namely in Mrs. A breast swelling scale 1 and in Mrs. T scale 2. The results of the study can be concluded that there is an effect of cabbage leaf compresses on the scale of breast swelling in both respondents.
Strategi dan Inovasi Pemasaran dalam Mempertahankan Stabilitas Omzet Vitamin C (Brand Hevit-C) Selama dan Pasca Covid-19 di Apotek Wilayah Jakarta Piter Piter; Anisa Indah Saputrie
OBAT: Jurnal Riset Ilmu Farmasi dan Kesehatan Vol. 2 No. 5 (2024): September : OBAT: Jurnal Riset Ilmu Farmasi dan Kesehatan
Publisher : Asosiasi Riset Ilmu Kesehatan Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.61132/obat.v2i5.708

Abstract

The Covid-19 pandemic has significantly altered the landscape of the healthcare product market, with a rapid increase in demand for Vitamin C as a means to enhance immune function. Amidst intensifying competition, Hevit-C, a well-known brand in Jakarta's pharmacies, has employed marketing strategies and innovations to maintain its revenue stability. This study aims to analyze various marketing strategies and innovations implemented by Hevit-C during and post-pandemic, and to identify the correlation between these strategies and innovations with the brand's revenue stability. The research methodology includes sales data analysis, collection of data related to marketing strategies and innovations used by product management, and a review of literature on marketing strategies in the pharmaceutical industry. It is anticipated that the findings of this research will benefit healthcare professionals and pharmacies by providing insights and educational materials on the use of Vitamin C for patients and the general public. Furthermore, the study aims to benefit the pharmaceutical industry by optimizing marketing strategies and better meeting market demands.
Deskripsi Cemaran Logam (Hg, Cu, Cd) pada Madu Asli, Madu Budidaya dan Madu Merk dengan menggunakan Metode ICP-AES Wina Fransiska; Wahidin Wahidin
OBAT: Jurnal Riset Ilmu Farmasi dan Kesehatan Vol. 2 No. 5 (2024): September : OBAT: Jurnal Riset Ilmu Farmasi dan Kesehatan
Publisher : Asosiasi Riset Ilmu Kesehatan Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.61132/obat.v2i5.711

Abstract

Honey is derived from plant nectar and pollen collected by bees. Honey contains natural sugars and nutrients but is prone to contamination by heavy metals such as mercury, copper, and cadmium from the environment. Honey quality standards stipulate maximum limits of contamination according to SNI 8664:2018. This study examined copper, mercury, and cadmium levels in native, cultivated, and branded honey using ICP-AES. Samples were randomly collected at the Laboratory of Pharmacy Faculty of University 17 August 1945 and metal levels were determined at the Regional Health Laboratory of DKI Jakarta Province from April-July 2024. Results showed all samples contained copper below the maximum limit of 5.0 mg/kg in the order of 0.243; 0.399; 0.297 mg/kg. Cadmium and mercury in the three honeys were undetected according to SNI's respective maximum limits of 0.2 and 0.03 mg/kg. Therefore, honeys of the three types met quality standards and are safe for consumption.
Peran Self-Efficacy dalam Kepatuhan Terhadap Pengobatan Penyakit Fibromyalgia Luthfiah Mawar; M. Agung Rahmadi; Helsa Nasution; Milna Sari
OBAT: Jurnal Riset Ilmu Farmasi dan Kesehatan Vol. 2 No. 5 (2024): September : OBAT: Jurnal Riset Ilmu Farmasi dan Kesehatan
Publisher : Asosiasi Riset Ilmu Kesehatan Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.61132/obat.v2i5.716

Abstract

Fibromyalgia is a chronic disorder characterized by widespread muscle pain and fatigue, often accompanied by psychological symptoms such as anxiety and depression. Medication adherence is crucial for managing this condition, yet many patients struggle to follow prescribed regimens. This study aims to explore the role of self-efficacy in medication adherence among fibromyalgia patients through a systematic review and meta-analysis. The researcher conducted a literature search in major electronic databases to identify relevant studies published between 2015 and 2023. Out of 1,247 identified articles, 18 studies met the inclusion criteria and were eligible for analysis. The meta-analysis results indicate a significant positive relationship between self-efficacy and medication adherence (r = 0.42, 95% CI [0.35, 0.49], p < 0.001). Moderator analysis revealed that this relationship is stronger among patients receiving self-efficacy-based interventions compared to those receiving standard care. These findings underscore the importance of integrating self-efficacy enhancement strategies into fibromyalgia management to improve medication adherence, ultimately leading to better patient health outcomes.
Pengaruh Variasi Minuman Serbuk Kombinasi Daun Binahong (Anredera Cordifolia (Ten) Steenis) dan Daun Mint (Mentha Piperita L.) terhadap Radikal DPPH (1,1-diphenyl-2-picrylhydraz) Ni Putu Laras Ayu Ningrat; Wintariani Wintariani; Ngurah Mayun
OBAT: Jurnal Riset Ilmu Farmasi dan Kesehatan Vol. 2 No. 5 (2024): September : OBAT: Jurnal Riset Ilmu Farmasi dan Kesehatan
Publisher : Asosiasi Riset Ilmu Kesehatan Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.61132/obat.v2i5.720

Abstract

Background:  Air pollution has become a serious issue, prompting considerations on obtaining essential substances known as antioxidants for the body. Preventive measures can be taken by utilizing herbal plants such as binahong and mint, known for their antioxidant properties.Objective: Measure the activity of the radical barrier of DPPH powder drink. Method: This study was a genuine research type. Results: Phytochemical screening revealed the presence of alkaloids, tannins, and saponins in the positive samples. The inhibition activity results for single formulations were as follows: binahong formulation 83,835%, mint formulation 85,011%, formulation (1 : 1) 83,043%, formulation (1 : 2) 83,210%, and formulation (2 : 1) 81,259%. Organoleptic tests indicated that formulation III was acceptable based on sensory evaluation. Conclusion: The powdered drink combination of binahong and mint leaves contains antioxidant compounds: alkaloids, flavonoids, tannins, and saponins. The highest DPPH radical scavenging activity was observed in the single mint leaf formulation and the lowest barrier is in combination powder drinks with (1 : 1) formulation, and formulation (1:1) was most acceptable based on sensory evaluation and there is no influence of variation between powdered drink formulation series..    
The role of Tenascin-X, Paraoxonase 1 and some other biochemical parameters in infertility women Yasameen Abdulhuussien Salman; Saif. M. Hasan; Nagham Qasim Kadhim
OBAT: Jurnal Riset Ilmu Farmasi dan Kesehatan Vol. 2 No. 5 (2024): September : OBAT: Jurnal Riset Ilmu Farmasi dan Kesehatan
Publisher : Asosiasi Riset Ilmu Kesehatan Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.61132/obat.v2i5.733

Abstract

The thyroid interact with the hypothalamic-pituitary reproductive axis. Tenascins (TN) are a group of versatile glycoproteins found in the extracellular matrix (ECM) that have distinct expression patterns in different tissues and stages of development, as well as in homeostasis tissue balance and during infections and diseases. Furthermore there  are   four types of  family members that are referred as  tenascin (-C,-R,-X, -W).Tenascin-X and tenascin-C have significant involvement in human diseases. The paraoxonase family consists of three genes: paraoxonase 1, paraoxonase 2, and paraoxonase 3. These genes have around 70% genetic sequence similarity and 60% same sequence of amino acid. Materials and Methods: 120  Sample of the current study were collected from married women aged 20 and 45 years after taking their information (age, height, weight, and health status in detail) to obtain suitable samples.  Results : The anti-mullerian hormone showed significant decrease at (P<0.01) in hypothyroidism and increase significant in infertility at (P<0.01). Prolactin showed highly increase significant in hypothyroidism at (P<0.01) and in infertility women patients compared with women control . Luteinizing hormone level showed increase significant in hypothyroidism and infertility at (P<0.01)  and follicle-Stimulating hormone level showed decrease significantly .The tenascin-X showed a high significant increase at (P<0.01) in  hypothyroidism patient compared with control group. The optimal cut-off value tenascin-X was (10.382 pg/ml as cut-off value). The tenascin-X showed a high significant increase at in infertility with hypothyroidism women patient compared with control group. The optimal cut-off value for tenascin-X was (8.904 pg/ml) . Albumin level showed decrease significant in hypothyroidism at (P<0.01) and increase significant in hypothyroidism and infertility patients at (P<0.01) with control group. Conclusions: Hypothyroidism is associated with changes in the level of sex hormones, which is one of the main causes of infertility . tenascin-X were related with hypothyroidism. Hypothyroidism is associated with oxidative stress, PON-1conseder anti-oxidant and activity is changes in oxidative stress of different etiology.
The Effect of Some Heavy Metals on Kidney Tissue and Function Asmaa Khalid Matni
OBAT: Jurnal Riset Ilmu Farmasi dan Kesehatan Vol. 2 No. 5 (2024): September : OBAT: Jurnal Riset Ilmu Farmasi dan Kesehatan
Publisher : Asosiasi Riset Ilmu Kesehatan Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.61132/obat.v2i5.738

Abstract

This research tested the effect of cadmium chloride and lead acetate on kidney function and their impact on kidney tissues. The study included (30) white rats that were randomly divided into (6) groups:- The control group takes plain water orally for 30 days, the group that was given CdCl2 (5 mg/kg) of body weight, the group that was given CdCl2 10 mg/kg of body weight, the group that was given lead acetate 50 mg/kg of body weight, the group that was given lead acetate 100 mg/kg of body and the group that was given cadmium chloride 5mg/kg with lead acetate 50 mg/kg body weight with drinking water for a month .The results shown in Table (1) indicated a significant increase (P < 0.05) in the levels of urea, creatinine, and uric acid in the serum of groups treated with CdCl2 at doses of 5 and 100 mg/kg, and the groups treated with lead acetate at doses of 50 and 100 mg/kg, as well as the group that received CdCl2 at a dose of 5 mg/kg along with lead acetate at a dose of 50 mg/kg, comparison with the healthy group .As for histological sections, the results showed the following section of the renal of the group treated with cadmium chloride 5 mg/kg shows atrophic renal glomerulus, necrosis of cells lining Bowman’s capsule , necrosis of cells lining the convoluted tubule  and a large increase in the space between the glomerulus and the capsule. As for the group treated with high-dose cadmium chloride showing necrosis of cells lining the glomerulus  and degeneration of cells lining the renal tubules Fragmentation of the glomerulus. As for the group treated with lead acetate at a dose of 50 mg/kg showing renal glomerulonephrosis, proximal and distal convoluted tubule necrosis, and periglomerular space in an almost normal manner. A section of the kidney of the group treated with with high-dose lead acetate, showing atrophy of some renal glomeruli and congestion of blood vessels and showing blood congestion within the kidney tissue, and decomposition of the cells lining the urinary tubules , Cross-section of the kidney of the group treated with cadmium chloride 5 mg/kg and lead acetate 50 mg/kg body weight Shows destruction of renal glomeruli  and swelling of renal tubule cells and necrosis of the kidney tissue with the appearance of hemorrhage Comparison with the healthy group
Uji Aktivitas Antibakteri Ekstrak, Fraksi Air, Fraksi Etil Asetat, Fraksi n-Heksan Daun Petai Cina (Leucaena leucocephala) Terhadap Bakteri Staphylococcus aureus ATCC 25923 Muhammad Andira Ibnu Shina; Tatiana Siska Wardani; Kusumaningtyas Siwi Artini
OBAT: Jurnal Riset Ilmu Farmasi dan Kesehatan Vol. 2 No. 6 (2024): November : OBAT: Jurnal Riset Ilmu Farmasi dan Kesehatan
Publisher : Asosiasi Riset Ilmu Kesehatan Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.61132/obat.v2i6.785

Abstract

Shina, mai., 2024, test of antibacterial activity of extract, water fraction, ethyl acetate fraction, and n-hexane fraction of chinese petai leaf (leuncaena leucocephala) against staphylococcus aureus atcc 25923, thesis, faculty of health sciences, duta bangsa university, surakarta one of the traditional medicines that currently has the potential to be developed is the chinese petai plant (leucaena leucocephala). Chinese petai leaves are used by the people of indonesia as a remedy for new and swollen wounds. Staphylococcus aureus is a gram-positive coccus bacterium that is the main pathogen in humans. Almost everyone has experienced a wide variety of staphylococcus aureus infections during their lifetime, from severe food poisoning to minor skin infections. The methods used in this study are diffusion and dilution. The purpose of this study was to determine the antibacterial activity of water extracts and fractions, ethyl acetate fractions, and n-hexane fractions of chinese petai leaves (leuncaena leucocephala), to find the most active extracts and fractions based on their inhibitory zones, and to determine the khm and kbm of the most active extracts against staphylococcus aureus atcc 25923. Based on research conducted on ethanol extract, water fraction, ethyl acetate fraction, and n-hexane fraction of chinese petai leaves have antibacterial activity against staphylococcus aureus atcc 25923. The most active extract in inhibiting staphylococcus aures atcc 25923 judging from its inhibition zone value is ethanol extract. Ethanol extract of chinese petai leaves has the same khm and kbm values, namely at a concentration of 25%.

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