cover
Contact Name
Fairuz Rifani
Contact Email
fairifani@gmail.com
Phone
+6281320419383
Journal Mail Official
ophthalmol.ina@gmail.com
Editorial Address
Gedung Baile, Lantai 1 Ruang 101 - 103 Jl. Kimia No 4, Menteng, Jakarta
Location
Kota adm. jakarta pusat,
Dki jakarta
INDONESIA
Ophthalmologica Indonesiana
ISSN : 01261193     EISSN : 2460545X     DOI : 10.35749
Core Subject : Health,
Ophthalmologica Indonesiana is an open accessed online journal and comprehensive peer-reviewed ophthalmologist journal published by the Indonesian Ophthalmologist Association / Perhimpunan Dokter Spesialis Mata (PERDAMI). Our main mission is to encourage the important science in the clinical area of the ophthalmology field. We welcome authors for original articles (research), review articles, interesting case reports, special articles, clinical practices, and medical illustrations that focus on the clinical area of ophthalmology medicine.
Articles 869 Documents
ANALYSING THE SIDE EFFECT OF AMIODARONE N CONSUMPTION ON OPTIC NERVE HEAD, CONTRAST SENSITIVITY AND COLOR VISION IN ARRYTHMIA PATIENT: Oral Presentation - Observational Study - Resident Callina Floriana Y. Br. Bangun; Bobby Ramses Erguna Sitepu; Delfi
Majalah Oftalmologi Indonesia Vol 49 No S2 (2023): Supplement Edition
Publisher : The Indonesian Ophthalmologists Association (IOA, Perhimpunan Dokter Spesialis Mata Indonesia (Perdami))

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35749/prmxk467

Abstract

Abstract Introduction & Objectives : To analyze the side effect of duration consumption of amiodarone on ONH, contrast sensitivity and color vision in arrythmia patient Methods : This study was an analytical observational study with cross sectional design. A total of 23 subjects with arrhythmias taking amiodarone were included in the study. Sampling was carried out from April 2022-August 2022 at the Eye Polyclinic and Cardiology Polyclinic. Results : Most of the subjects were female, 12 people (52.2%) with a mean age of 59 years. The results of the examination showed that two subjects had decreased vision, ONH edema and decreased contrast sensitivity in the right eye where the mean duration of amiodarone consumption was 4.5 months. The results of binocular color vision examination were normal in all study subjects. There was a significant effect of the consumption duration of amiodarone on ONH (p=0.024) and on contrast sensitivity (p=0.022) Conclusion : There was a significant effect of the duration consumption of amiodarone on ONH and contrast sensitivity in arrythmia patient
EFFECT OF TOPICAL BRIMONIDINE ON NMDA RECEPTOR EXPRESSION AND RETINA GANGLION CELL DENSITY IN TRAUMATIC OPTIC NEUROPATHY RATS MODEL: Oral Presentation - Experimental Study - Resident RR. WIDYASTUTI PASPARINI; Riski Prihatningtias; Arief Wildan; Hermawan Istiadi
Majalah Oftalmologi Indonesia Vol 49 No S2 (2023): Supplement Edition
Publisher : The Indonesian Ophthalmologists Association (IOA, Perhimpunan Dokter Spesialis Mata Indonesia (Perdami))

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35749/bz09ta84

Abstract

Abstract Introduction & Objectives : Traumatic optic neuropathy is a visual disturbance caused by acute injury to the optic nerve which results in retinal ganglion cell apoptosis through the glutamate excitotoxicity pathway. Brimonidine is an alpha 2-receptor agonist that acts as a neuroprotector in the glutamate excitotoxicity pathway and causes modulation of NMDA receptors associated with glutamate. Objective of this study is to prove the effect of topical brimonidine on NMDA receptor expression and retinal ganglion cell density in a rat model of traumatic optic neuropathy Methods : Rat models of traumatic optic neuropathy was carried out using the optic nerve crush method. The treatment group was given topical brimonidine 0.15% 1 drop/12 hours for 14 days. NMDA receptor expression was assessed by immunohistochemical staining and retinal ganglion cell density was assessed by Hematoxylin-eosin staining. Statistical analysis was performed to assess the correlation between NMDA receptor expression and retinal ganglion cell density Results : The Allred score of NMDA receptors expression in the treatment group was lower than control group, with significant difference (p=0.002). The mean density of retinal ganglion cells in the treatment and control group was 20,99  7,76 and 12,51  3,10, respectively with a significant difference (p=0.032). There was a significant correlation between NMDA receptor expression and retinal ganglion cell density in the treatment group (p=0.035) with strong negative correlation (r= -0.611) Conclusion : Topical administration of brimonidine to the Wistar rat model of traumatic optic neuropathy can suppress NMDA receptor expression and maintain retinal cell ganglion density
Retinal Nerve Fiber Layer as The Preferred Objective Measure in Differentiating Pseudopapilledema with True Papilledema: A Systematic Review: Oral Presentation - Observational Study - General practitioner Lourisa Ruth Eldenia; Rona Ali Badjrai; Lazuardiah Anandi; Fierda Ovita Azhari; Erika Anggraini; Brigitta Marcia Bidihardja; Syntia Nusanti
Majalah Oftalmologi Indonesia Vol 49 No S2 (2023): Supplement Edition
Publisher : The Indonesian Ophthalmologists Association (IOA, Perhimpunan Dokter Spesialis Mata Indonesia (Perdami))

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35749/pcx3g043

Abstract

Abstract Introduction & Objectives : Distinguishing pseudopapilledema from true papilledema may generate confusion for some cases. Regardless of the subjective judgment on clinical examination alone, objective measurement for confirmation of diagnosis might be costly, operator-dependent, invasive, or not readily available. This study aims to evaluate whether retinal nerve fiber layer (RNFL) could be the reliable and efficient objective measure to ascertain the diagnosis. Methods : Literatures were obtained by comprehensive searching on PubMed, ProQuest, Google Scholar, and Cochrane between 2012 - 2023. Last search was March 26, 2023. Non-english study, animal study, review articles, case studies, and editorial letters were excluded. We included studies with available full-text containing both groups of papilledema and pseudopapilledema. The result was presented according to Preferred Reporting Items for Systematic Review and Meta-Analyses (PRISMA) guideline. Results : A total of 615 participants were included from 8 different studies all comprising a group of papilledema and pseudopapilledema with or without optic disc drusen (ODD). Studies resulted in good accuracy on RNFL in differentiating pseudopapilledema with papilledema as the area under curve ranging from 0,78 to 0,91. However, specificity and sensitivity were varied between 65-100% and 33-91% respectively. Lower accuracy was found when pseudopapilledema only includes patients with ODD or papilledema was narrowed to mild papilledema. Conclusion : RNFL is a useful objective measure with favorable accuracy in differentiating pseudopapilledema with papilledema especially in acute settings or whenever operator-dependent examination is not obtainable
Successful Therapy and Relapse Rates of Typical and Atypical Optic Neuritis: Oral Presentation - Observational Study - Ophthalmologist M.HIDAYAT; Havilah Zeki Rosa
Majalah Oftalmologi Indonesia Vol 49 No S2 (2023): Supplement Edition
Publisher : The Indonesian Ophthalmologists Association (IOA, Perhimpunan Dokter Spesialis Mata Indonesia (Perdami))

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35749/q4wt4t09

Abstract

Abstract Introduction & Objectives : The annual incidence of Optic Neuritis (ON) has been reported increased, 0.56 and 5.1 cases per 100,000. Early diagnosis is essential to prompt an appropriate treatment, define the successfulness of therapy, and identify the incidency of relapse. The availability of neuroimaging (CT Scan, MRI) supporting diagnosis accuracy thus increase the incidence number. This paper aims at presenting the successful therapy and relapse rates of typical and atypical ON. Methods : This is an observational study towards typical and atypical ON. The sample is every patient who diagnosed with ON in the neuroophthalmology outpatient policlinic of M Djamil Hospital from January 2017 to December 2022. The sample should meet the inclusion and exclusion criteria. Every patients were treated using Optic Neuritis Treatment Trial (ONTT) protocol. The data respecting clinical characteristics, treatment results, and relapse is being collected and analyzed. Results : We collected 50 subject who meets the ON criteria, involving 69 eyes. It mostly affected women (66%), less than 50 years old (88%), unilateral (62%), and have no systemic disease (76%). The visual acuity is increased after treatment in 92.8%. 7.2% not getting better, and no visual acuity worsening. We found 2 relapse cases (4%), 1 affected the same eye, and another involve the fellow eye. Conclusion : The successful rate of therapy in typical and atypical ON is quite good. But, some patients with clinically severe ON, have systemic diseases such as diabetes, and late for treatment didn't have an improvement even after therapy. Relapse cases is found in small percentage.
Effects of Dark Chocolate and Milk Chocolate consumption on Sub foveal Choroidal Thickness in healthy young subject: A Randomized double-blind Cross over Study: Oral Presentation - Experimental Study - Ophthalmologist LA ODE HAMZAH; YUNITA, MD; BATARI TODJA UMAR, MD
Majalah Oftalmologi Indonesia Vol 49 No S2 (2023): Supplement Edition
Publisher : The Indonesian Ophthalmologists Association (IOA, Perhimpunan Dokter Spesialis Mata Indonesia (Perdami))

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35749/wvjtnn87

Abstract

Abstract Introduction & Objectives : Dark Chocolate consumption was known to effect blood flow and to date there is little information about this effect to human eye. We aim to compare the effect of consuming dark chocolate (DC) and milk chocolate (MC) on sub foveal choroidal thickness (SFCT) and blood pressure (BP) in healthy young subject Methods : A randomized double blind cross over study was used. We randomly assigned subjects into two group. First group consumed DC and then MC at least 72 hours later and the second group consumed MC and then DC. BP and SFCT was measured at baseline, 30 minutes and 2 hours after consumption for each group Results : Data from two group (Group A; 40 eye/20 subject, age 26 -36 years and group B; 40 eye/20 subject, age 27 -34 years) were collected. There was an increase on SFCT at 30 minutes (DC 11.05 ± 13.720 μm, p>0.01; MC 4.40 ± 8.040 μm, p>0.01) and 2 hours (DC 23.45 ± 11.581 μm, p>0.01; MC 9.92 ± 11.288 μm, p>0.01) after consumption compare to baseline. There were no changes found on BP and there was no correlation found between BP and SFCT changes Conclusion : This study found that there was a significant increase in SFCT especially in DC consumption in 30 minute and 2 hours after consumption. There were no changes in BP and No correlation was found between BP and SFCT changes
DERAJAT APOPTOSIS SEL GANGLION RETINA PASCA PEMBERIAN TAMBAHAN EKSTRAK MORINGA OLEIFERA ORAL DIBANDINGKAN DENGAN TERAPI STANDAR Studi Eksperimental pada Tikus Wistar Model Methanol Toxic Optic Neuropathy: Oral Presentation - Experimental Study - Resident ADELIA BAYU ISFANDIARI; RISKI PRIHATNUNGTIAS; FIFIN LUTHFIA RAHMI
Majalah Oftalmologi Indonesia Vol 49 No S2 (2023): Supplement Edition
Publisher : The Indonesian Ophthalmologists Association (IOA, Perhimpunan Dokter Spesialis Mata Indonesia (Perdami))

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35749/t5yryf15

Abstract

Abstract Introduction & Objectives : Methanol toxic optic neuropathy can lead to retinal ganglion cell apoptosis which causes visual disturbance. Moringa oleifera has been reported to have an anti-inflamatorry effect that can prevent inflammatory mediators from being relased in methanol toxic optic neuropathy Methods : Twenty-one Wistar methanol toxic optic neuropathy were divided into 3 groups, namely base line group, control group that given intravenous methylprednisolone 4.5mg/6 hours for 3 days, and given standard theraphy and additional administration of oral Moringa oleifera 300mg/kgbodyweight/day for 4 weeks. Assessment of the degree of apoptosis by Anatomical Pathology with histopatolocigal scaoring. The study used Mann Whitney comparative hypothesis test (Significant p<0.05) Results : The degree of retinal ganglion cell apoptosis was significantly lower in the treatment and standard therapy groups compared to the base line group. The treatment group compared to the standard therapy group was not significantly different (p = 1,000) Conclusion : The degree of retinal ganglion cell apoptosis in rat model methanol toxic optic neuropathy was not significantly different between the group that was given additional oral Moringa oleifera extract compared to the standard theraphy group
THERMAL IMAGING ACCURACY ON CLINICAL ACTIVITY SCORE (CAS) THYROID EYE DISEASE PATIENTS: Oral Presentation - Experimental Study - Ophthalmologist MUHAMMAD REZA ARLAS; dr. Devi Azri Wahyuni, Sp.M, Sub.Sp NO, MARS
Majalah Oftalmologi Indonesia Vol 49 No S2 (2023): Supplement Edition
Publisher : The Indonesian Ophthalmologists Association (IOA, Perhimpunan Dokter Spesialis Mata Indonesia (Perdami))

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35749/47dvkd87

Abstract

Abstract Introduction & Objectives : Thyroid Eye Disease (TED) also known as Graves' ophthalmopathy, thyroid-associated orbitopathy, and other terms is an autoimmune inflammatory disorder with the most common extra-thyroid manifestations of Graves' Disease (GD). The disease phase is usually assessed clinically, by assessing the presence or absence of cardinal signs and symptoms of inflammation which are assessed in the form of a clinical activity score (CAS). In addition, the use of Thermal Imaging (IT) as a passive measurement technique that does not require contact with the patient (non-invasive and non- contact) and does not use ionizing radiation or contrast agents is another option. The use of TI in patients with TED still has minimal data and does not have more specific results. This study aims to determine the accuracy of TI and CAS images in TED patients. Methods : This study design is accuracy test at the Ophthalmology Polyclinic of RSUP Dr. Mohamad Hoesin Palembang in July 2021 until the sample is filled with 24 people. Thermal Imaging (TI) accuracy test was performed to establish active and inactive TED compared to CAS (Clinical Activity Score) in TED patients. Analysis of research results with SPSS version 22.0. Results : The result shown that the proportion of research subjects who were female was 17 people (70.8%) and male research subjects were 7 people (29.2%). At 7 locations the Thermal Imaging examination was found to have varying sensitivity Conclusion : Thermal Imaging can be used to help diagnose active and inactive TED.
HISTOLOGICAL FEATURES OF ETHAMBUTOL INDUCED MICE EYES: A PRE- EXPERIMENTAL STUDY ON TOXIC OPTIC NEUROPATHY CASE: Oral Presentation - Experimental Study - Ophthalmologist BATARI TODJA UMAR; Itzar Chaidir Islam
Majalah Oftalmologi Indonesia Vol 49 No S2 (2023): Supplement Edition
Publisher : The Indonesian Ophthalmologists Association (IOA, Perhimpunan Dokter Spesialis Mata Indonesia (Perdami))

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35749/tdpqn025

Abstract

Abstract Introduction & Objectives : Toxic Optic Neuropathy (TON) is a visual disease caused by toxic substances damaging the optic nerve. It can be caused by inflammation, infection, or long-term drug use. Over 10% of ethambutol- treated optic neuropathy patients developed major complications. Cellular changes should be observed histologically. This study examines ethambutol-induced mice's eye histology in the fibrous, vasculous, nervous tunica, optical media, and optic nerve tissue. Methods : This pre-experimental study used 20 eyes of 10 white mice aged 1-2 weeks weighing 50-65 grams. Group 1 consisted of healthy mice without therapy and group 2 received 35 mg/kgBW/day of ethambutol for 60 days. (group 2). Hematoxylin eosin staining was used to observe binocular experimental animal eyes after enucleation. All measurements used Olympus® CX-20 microscope with 40x objective resolution. Results : The average thickness of the cornea was 72.238 ± 10.542 and 60.572 ± 10.25, while the sclera was 336.533±40.851 μm and 331.339±34.219 μm. In groups 1 and 2, no significant changes were foundin the cell layer morphology of both tissues (p > 0.05). Iris, ciliary body, and choroid were observedin the tunica vasculosa. Groups 1 and 2 had eye and ciliary body lengths of 595.148±137.805 μm and 497.705±213.866 μm, respectively, and choroid thicknesses of 161.369±37.925 and 162.605±25.160 (p>0.05). Group 1 had 402.268±55.666 μm retinal thickness in the tunica nervosa, while group 2 had 399.854±27.585 (p>0.05). Conclusion : Ethambutol-induced and normal experimental animals had substantial histological differences in optic nerve thickness, but no significant difference in the other ocular structures.
When do Ophthalmology Residents Study to Prepare for The National Exam? Oral Presentation - Observational Study - Ophthalmologist WIDYANA; FELICIA WIDYAPUTRI; SUPANJI; MUHAMMAD BAYU SASONGKO
Majalah Oftalmologi Indonesia Vol 49 No S2 (2023): Supplement Edition
Publisher : The Indonesian Ophthalmologists Association (IOA, Perhimpunan Dokter Spesialis Mata Indonesia (Perdami))

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35749/s8v7c246

Abstract

Abstract Introduction & Objectives : Ophthalmology residents are occupied with clinical services in the hospital. They only have limited time to study. Since 2022, we established a progress test for residents to facilitate their study especially during the national examination preparation that is obligated to be completed once per year. To report the allocated time for completing the progress test by ophthalmology residents to inform educational centres about the recommended study time for residents. Methods : Data from the online progress test that was available from the Gadjah Mada eLearning (GAMEL) platform was extracted and analysed. The test was consisted of 60 multiple questions and opened for two weeks with a 24-hour access time. In this study, the scores, the time of the test, and time spent to complete the test were descriptively and quantitatively analysed. Results : Overall, 42 out of 55 (76.4%) and 42 out of 56 (75.0%) residents completed the progress test with a total test attempt of 60 and 51 times in 2022 and 2023, respectively. The mean score achieved was 43.3 (min-max 3.3-70.0). Majority of residents (65.8%) accessed the test at between 16.00 - 23.00 Western Indonesian Time (WIT), while 19.8% and 14.4% at between 09.00 - 16.00 and 03.00 - 9.00 WIT. The mean time spent to complete the test was 55.2  20.9 minutes. Conclusion : Most ophthalmology residents spent their time for completing the progress test after working hours with an average duration of less than an hour. Any national exam preparation programs can be scheduled in this time for better resident’s engagements.
Neutrophil-Lymphocyte Ratio as an Inflammatory Marker for Retrobulbar Optic Neuritis: Oral Presentation - Observational Study - Resident I Gusti Agung Made SIddhi Putra; Indra Yti Mahayana
Majalah Oftalmologi Indonesia Vol 49 No S2 (2023): Supplement Edition
Publisher : The Indonesian Ophthalmologists Association (IOA, Perhimpunan Dokter Spesialis Mata Indonesia (Perdami))

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35749/1y8bvf39

Abstract

Abstract Introduction & Objectives : Retrobulbar optic neuritis is a form of optic neuritis which part at the back of the eye become inflamed and demyelinated. The inflammatory response might be important for diagnosis and prognosis because in retrobulbar optic neuritis, everything seems normal anteriorly. This study aims to analyze the parameter changes of CBC in retrobulbar optic neuritis. Methods : Patients with retrobulbar optic neuritis who were admitted to the Yogyakarta Tertiary Hospital from January 2020 to March 2022 were included in this study. Age-matched healthy patients were recruited for comparison (controls). A venous blood sample was obtained as part of the examination at the first visit. The primary measure was white blood cells (WBC), while the secondary measures were neutrophil-to-lymphocyte ratio (NLR), platelet-lymphocyte ratio (PLR), lymphocyte-to-monocyte ratio (LMR), haemoglobin, platelets, neutrophils, and lymphocytes counts. Results : 20 Patients were enrolled in case group, with mean age 27.75(±10.9)Y.O. and 13(65%) of them were female. overall, 4(20%) patients had bilateral involvement. Erythrocytes(p=0.45), Haemoglobin(p=0.17), Haematocrit(p=0.126), Thrombocyte(p=0.86), Monocyte(p=0.68), LMR(p=0.26), PLR(p=0.074) were insignificantly different between both group. Meanwhile Neutrophil(p=0.006) and NLR(p=0.021) were significantly higher in case group also Lymphocyte(p=0.05), Eosinophil(p=0.004)and Basophil(p=0.016) were significantly lower in case group. Conclusion : The inflammatory Parameters such as Neutrophil and NLR were found to be significantly higher in retrobulbar optic neuritis patients although other parameters like WBC were insignificantly different, even some parameters like Lymphocyte were significantly lower in retrobulbar optic neuritis. thus, these parameters especially NLR might be attributable to the pathogenesis of retrobulbar optic neuritis even when the WBC seems in normal limit.