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Trends in Infection and Global Health
Published by Universitas Syiah Kuala
ISSN : 2806646x     EISSN : 2806646x     DOI : https://doi.org/10.24815/tigh.v1i2.23580
Core Subject : Health, Science,
Biochemistry, Genetics & Molecular Biology Health Professions Immunology & microbiology Medicine & Pharmacology Public Health
TIGH publishes primary research papers, review articles, short communications and letters on the following topics: Tropical diseases Microbiology Epidemiology Public health Population health One Health Immunology Chronic diseases Surgical disease and surgical care Chemotherapy and pharmacology Maternal and child health Clinical tropical medicine
Arjuna Subject : Kedokteran - Kedokteran (Lain-Lain)
Articles 5 Documents
 1 
Search results for , issue "Vol 2, No 2 (2022): December 2022" : 5 Documents clear
A case of extensive verrucosis in 45-year-old women and CD4 lymphopenia treated with electrodessication using general anesthesia and isoprinosine Wahyu Lestari; Sri Lestari
Trends in Infection and Global Health Vol 2, No 2 (2022): December 2022
Publisher : School of Medicine, Universitas Syiah Kuala

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24815/tigh.v2i2.27913

Abstract

The human papilloma virus (HPV) is a viral infection that has a broad variety of clinical manifestation. The clinical manifestation really depends on the type of HPV virus and the immunity status of the host, particularly the cell-mediated immunity. Extensive verrucosis is one of the significant clinical manifestation of a disseminated HPV infection that is related with a severe immunodeficiency status. Electrodessication or laser surgery is a method of treatment that could directly destroy the lesion in one time. We described a case of a 45 years-old woman with extensive verrucosis. The patient complained multiple warts lesion on the hands, face, neck, lower arms and lower extremities since eight years ago. Physical examination revealed on the dorsum and palmar hands, both of finger nails (I, II, III, and IV), face (forehead and cheeks), anterior of neck, lower arms and 2/3 distal of lower extremities part anterior, there were single and groups of flesh coloured papules and flesh coloured plaques, skin colour papules with flat topped, greyish papules and greyish plaques with verrucous surfaces and brownish crusts. The CD4 count of the patient was 91 cells/µL. Skin biopsy and histopathology examinations showed hyperkeratosis, papillomatosis, and acanthosis with vacuole cell (koilocytes). The patient was treated with electrodessication using general anaesthesia and isoprinosine 3x500 mg. The result after two weeks post-treatment showed that there were no new lesions appeared on post electro surgery site. This case highlights the importance of the treatment for the success of extensive verrucosis with CD4 lymphopenia.
SARS-CoV-2 infection and male fertility problems Ika Inda Bani; Zulkarnain Zulkarnain; Gholib Gholib; Dedy Syahrizal; Fauzul Husna; Winda Yulia; Mulkan Azhari
Trends in Infection and Global Health Vol 2, No 2 (2022): December 2022
Publisher : School of Medicine, Universitas Syiah Kuala

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24815/tigh.v2i2.29426

Abstract

In 2019, the coronavirus disease 2019 (COVID-19) pandemic, caused by severe acute respiratory syndrome corona virus 2 (SARS-CoV-2), has killed more than 6.6 millions of people around the world as of end of 2022. The long-term impact of COVID-19 is persisted, including its impact on male reproduction. SARS-CoV-2 enters into host cells using the angiotensin-converting enzyme 2 (ACE2) and transmembrane serine protease 2 (TMPRSS2) receptors. Both of these receptors are expressed more in men, and therefore men are more susceptible to SARS-CoV-2. COVID-19 potentially cause infertility by damaging testicular tissues and interfering with the process of spermatogenesis. A decrease in serum levels of testosterone, follicle-stimulating hormone (FSH) and luteinizing hormone (LH) as well as a decrease in sperm quality in men with COVID-19 compared to healthy men of the same age has been reported in several studies. Utilizing existing research data, this study aims to explore in detail of how SARS-CoV-2 tends to affect male fertility.
Bacterial pathogens associated with eyeglasses and risks of infection: A cross-sectional study in South-West Nigeria Seyi Samson Enitan; Okeoghene Marcel Edafetanure-Ibeh; Grace Eleojo Itodo; Michael Olugbamila Dada; Grace Oluwatoyin Mensah-Agyei; Richard Yomi Akele; Stephen Olasebikan Makanjuola; Saratu Omagbemi Ajike; Nwachi Idume Ogbonna; Jamiu Monsur Olalekan
Trends in Infection and Global Health Vol 2, No 2 (2022): December 2022
Publisher : School of Medicine, Universitas Syiah Kuala

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24815/tigh.v2i2.28488

Abstract

Ocular infections have been associated with bacterial contamination of eyeglasses. This study assessed bacterial contaminants associated with the eyeglasses of the staff and students of Babcock University, Ilishan-Remo, Ogun State, Nigeria. A total of 100 participants comprising 33 males and 67 females (aged 16-76 years) were recruited for the study after obtained the written informed consents. A structured questionnaire was used to collect the demographic and clinical information. A total of 100 eyeglasses were examined for bacterial contamination using standard bacteriological methods. A one–way analysis of variance (ANOVA) and Tukey–Kramer multiple comparisons test were used to determine the differences between the bacterial loads among the eyeglasses of study participants. We found that the percentage of eyeglass lenses with unacceptable levels of contamination (105CFU/mL) and acceptable levels of contamination were 19% and 46%, respectively. The percentages of eyeglass handles with unacceptable and accepted level of contamination were 49% and 7%, respectively. Most of the isolated bacteria were sensitive to the tested antibiotics. Risk factors associated with bacterial contamination of eyeglasses were exposure to dusty environment, irregular cleaning, and poor compliance with eyeglass care guidelines. Our study further underscores the claim that eyes glasses may serve as potential vehicles for bacteria capable of causing ocular infections.
Profile of antibiotic susceptibility test of bacterial pathogens isolated from the hands of university students in Nigeria John Cletus Ihongbe; Salter Oluseun Aramide Adeyemo; Seyi Samson Enitan; Michael Olugbamila Dada; Oluchi Gladys Ofem; Effiong Effiong Joseph; Chinenye Alaezi Okorochi; Nwachi Idume Ogbonna
Trends in Infection and Global Health Vol 2, No 2 (2022): December 2022
Publisher : School of Medicine, Universitas Syiah Kuala

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24815/tigh.v2i2.29972

Abstract

The aim of this study was to assess bacterial contaminants isolated from hands of undergraduate students of Babcock University, Nigeria. A total number of 200 students (100 males and 100 females) were randomly recruited and hand swabs were collected and inoculated on MacConkey and chocolate Agar. The biochemical tests were conducted to identify the bacterial isolates and antibiotic susceptibility testing was carried out using the disc diffusion method. Out of the 200 participants examined, bacterial contaminants were recovered from 154 (77.0%). The most frequently isolated organisms were Staphylococcus aureus (32.5%), followed by Escherichia coli (26.6%), coagulase negative Staphylococcus (20.8%) and then Klebsiella pneumoniae(20.1%). The antibiotic sensitivity showed that all coagulase negative Staphylococcus isolates were sensitive to ceftriaxone, levofloxacin, ciprofloxacin, imipenem, ofloxacin and azithromycin, but less sensitive to cefuroxime (50.0%) and amoxicillin (60.0%). S. aureus was sensitive to levofloxacin, ofloxacin, gentamycin and azithromycin while for Gram negative bacteria, E. coli was 100% sensitive to levofloxacin, imipenem, cefuroxime, ofloxacin, and ampiclox, but less sensitive to amoxicillin (20.0%). Klebsiella pneumoniae was sensitive to ceftriaxone and gentamycin, 100% and 90.0%, respectively, but less sensitive to amoxicillin (20.0%). In conclusion, some bacteria exist on the hands of undergraduate students of Babcock Students with varied antibiotic susceptibility patterns and therefore institutional implementation of hand hygiene practices should be implement among students in the university.  
A study of wound healing process in post total laryngectomy patients: Serial case reports Srifia Wardianti; Iskandar Zulkarnain; Benny Kurnia; Lily Setiani; Fadhlia Fadhlia; Safarianti Safarianti
Trends in Infection and Global Health Vol 2, No 2 (2022): December 2022
Publisher : School of Medicine, Universitas Syiah Kuala

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24815/tigh.v2i2.29360

Abstract

Laryngeal carcinoma is a malignancy on larynx that may occur in glottic, supraglottic and subglottic. Larynx plays role in coordination of upper aerodigestive tract such as breathing, verbal and swallowing. This reported as the third most common malignancy in the ENT-HN department. Total laryngectomy is a procedure that performed on T3 and T4 lesions. The most common complication is prolonged of the wound healing process. The process is very complex  consist of four overlapping phases that involve multifactorial divided into local and systemic factors. Local factors include oxygenation and infection, while systemic factors are age, gender, psychological stress, nutrition, chronic disease and immunocompromise conditions. In this case, seven patients underwent total laryngectomy and contributing factors of wound healing process were observed in each patient until 14th postoperative day. Some of important factors might contributed to the wound healing process in some patients such as psychological stress, nutrition and chronic disease such as diabetes mellitus and hypertension.

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