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Dwi Endah Kusumawati
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INDONESIA
Indonesian Journal of Medical and Pharmaceutical Science
Published by Universitas Islam Sultan Agung
ISSN : -     EISSN : 28096576     DOI : -
Core Subject : Health, Science,
Chemistry Health Professions Immunology & microbiology Medicine & Pharmacology Public Health
This journal accepts and publishes academic articles focusing on theory, methods, and applications in: 1) Pharmaceutical science 2) Biomedical science 3) Herbal medicine 4) Clinical pharmacy 5) Drug discovery
Arjuna Subject : Pharmacology, Toxicology and Pharmaceutics - Pharmacology, Toxicology and Pharmaceutics (Lain-Lain)
Articles 52 Documents
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ANALISIS PERBEDAAN BIAYA RIIL DENGAN TARIF INA-CBG’s DAN FAKTOR YANG MEMPENGARUHINYA UNTUK CHRONIC KIDNEY DISEASE PADA ERA JAMINAN KESEHATAN NASIONAL Indriyati Hadi Sulistyaningrum; Arifin Santoso; Binarti
Indonesian Journal of Medical and Pharmaceutical Science Vol. 1 No. 1 (2022)
Publisher : Sultan Agung Islamic University of Semarang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30659/ijmps.v1i1.2

Abstract

Background: The National Social Security System (SJSN) is a system in the health sector that aims to provide comprehensive social security in order to create a just, prosperous and prosperous society. According to WHO growth in the number of Chronic Kidney Disease in 2013 increased by 50% from 2012 even in Southeast Asia to the number of sufferers of Chronic Kidney Disease> 380 million people. While in Indonesia, it has increased by 10% every year. This study aims to determine the differences between INA-CBG rates and the real costs of JKN-era Chronic Kidney Disease patients in RSISA Semarang. Method: This research is an observational study with a retrospective analytic descriptive design with quantitative data. The method used is the Cross Sectional method that makes observations, and can describe the factors that influence the real cost of hospitals. The population was 589 patients with Chronic Kidney Disease and 238 patients and analyzed using the chi-square statistical test with p-value <0.05. Results: The results of the study that as many as 14 patients (5.9%) aged 18-28 years, as many as 50 patients (21.0%) aged 29-39 years, as many as 82 patients (34.5%) aged 40-50 years , as many as 68 patients (28.6%) aged 51-60 years, as many as 21 patients (8.8%) aged 61-70 years as many as 3 patients (1.3%) aged 71-80 years. The research results obtained a p-value of 0,000. Conclusion: There is a Difference between Hospital Real Costs and INA-CBG's Rates for Chronic Kidney Disease in JKN Era in Semarang Hospital in 2018. There are no factors that affect the real costs in chronic kidney disease patients JKN participants in 2018 both class of care, length of treatment (LOS), and disease severity.
PENGARUH PERAN APOTEKER TERHADAP READMISSION PADA PASIEN CONGESTIVE HEART FAILURE DI RSUD. MARGONO SOEKARJO (RSMS) PURWOKERTO Farrah Bintang Sabiti; A.D. Perwitasari; B Rahardjo
Indonesian Journal of Medical and Pharmaceutical Science Vol. 1 No. 1 (2022)
Publisher : Sultan Agung Islamic University of Semarang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30659/ijmps.v1i1.3

Abstract

Congestive Heart Failure (CHF) merupakan diagnosis tertinggi pada tingkat readmission. Terjadinya readmission merupakan salah satu pelayanan kesehatan buruk pada rumah sakit, dengan keterlibatan apoteker sangat berpengaruh terhadap kejadian readmission. Penelitian ini bertujuan untuk mengetahui hubungan intervensi apoteker dalam menurunkan tingkat readmission pada pasien CHF di RSMS. Penelitian ini merupakan penelitian observasi Cohort prospektif. Kelompok kontrol yaitu pasien yang tidak mendapatkan intervensi oleh apoteker, kelompok intervensi yaitu pasien yang mendapatkan intervensi berupa edukasi konseling dan follow up telepon oleh apoteker di RSMS. Dari hasil penelitian tidak terdapat hubungan peran apoteker dengan intervensi edukasi konseling dan follow up telepon dengan penurunan tingkat readmission pada pasien CHF di RSUD. Margono Soekarjo (RSMS). Hal ini dibuktikan dengan nilai (p) 0.322 dan (r) 0.178. dengan demikian bahwa apoteker saja tidak cukup dalam menurunkan tingkat readmission pada pasien CHF perlu adanya team kolaborasi dengan tenaga kesehatan di RSMS yang sangat berpengaruh dalam menurunkan readmission yang berkaitan dengan penekanan biaya pengobatan kesehatan pasien.
FAKTOR YANG BERPENGARUH PADA NIAT IMUNISASI MR (MEASLES RUBELLA) BERDASARKAN THEORY OF PLANNED BEHAVIOR DI PUSKESMAS HALMAHERA KOTA SEMARANG Willi Wahyu Timur; Nurul Syazwani; Chilmia Nurul Fatiha
Indonesian Journal of Medical and Pharmaceutical Science Vol. 1 No. 1 (2022)
Publisher : Sultan Agung Islamic University of Semarang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30659/ijmps.v1i1.4

Abstract

Latar Belakang : Theory of Planned Behavior merupakan teori yang digunakan untuk prediksi perilaku pendekatan psikologisosial untuk pemahaman dan memprediksi beberapa faktor penentu perilaku kesehatan.Theory of Planned Behavior terdiri dari tiga faktor penentu yaitu sikap, norma subjektif dan persepsi pengendalian diri. Menurut teori ini, perilaku dipengaruhi oleh niat. Penelitian ini bertujuan untuk mengetahui pengaruh penggunaan theory of planned behavior terhadap niat melakukan imunisasi MR di Puskesmas Halmahera Kota Semarang. Metode : Jenis penelitian analitik observasional dengan rancangan cross sectional. Populasi dalam penelitian ini adalah seluruh ibu yang membawa anaknya yang berusia 9-12 bulan yang belum diimunisasi MR awal ke puskesmas Halmahera kota Semarang. Jumlah sampel sebanyak 86 ibu dengan menggunakan convenience sampling. Data diperoleh melalui lembar kuesioner. Data diolah dengan menggunakan uji statistik regresi linier berganda. Hasil : Hasil penelitian menunjukkan bahwa ada pengaruh positif dan signifikan sikap terhadap niat ibu melakukan Imunisasi MR (p value 0,000). Ada pengaruh positif dan signifikan norma subjektif terhadap niat ibu melakukan imunisasi MR (p value 0,000). Ada pengaruh positif dan signifikan persepsi pengendalian diri terhadap niat ibu melakukan Imunisasi MR (p value 0,000). Ada pengaruh positif dan signifikan sikap, norma subjektif dan persepsi pengendalian diri secara bersama-sama terhadap niat ibu melakukan Imunisasi MR (p value 0,000). Kesimpulan : faktor yang berpengaruh pada niat imunisasi MR (measles rubella) berdasarkan theory of planned behaviordi Puskesmas Halmahera Kota Semarang yaitu sikap, norma subjektif dan persepsi pengendalian diri.
Pengaruh Variasi Konsentrasi Pada Sediaan Krim Ekstrak Daun Kelor (Moringa oleifera L) Terhadap Uji Aktivitas Antibakteri Staphylococcus aureus Fadzil Latifah; Ika Buana Januarti; Nur Amalina
Indonesian Journal of Medical and Pharmaceutical Science Vol. 1 No. 1 (2022)
Publisher : Sultan Agung Islamic University of Semarang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30659/ijmps.v1i1.5

Abstract

Latar Belakang : Bakteri Staphylococcus aureus merupakan penyebab penyakit antara lain jerawat, bisul, impetigo,dan infeksi pada luka. Beberapa senyawa yang terkandung didalam daun kelor berperan sebagai antibakteri. Tujuan penelitian ini adalah untuk mengetahui konsentrasi 5%, 10%, 15% sediaan krim ekstrak etanolik daun kelor (Moringa Oleifera L.) yang dapat menghambat pertumbuhan bakteri Staphylococcus Aureus. Metode : Penilitian ini bersifat eksperimental dengan post test only control group design. Ekstraksi menggunakan metode maserasi pelarut etanol 96%. Penelitian ini menggunakan 5 kelompok yaitu kontrol positif (K+), kontrol negatif (K-), formula 5% (F1), formula 10% (F2) dan formula 15% (F3). Pengujian sifat fisik sediaan krim meliputi organoleptis, pH, daya sebar dan viskositas. Uji efektivitas antibakteri menggunakan metode difusi cakram. Hasil : Hasil uji sifat fisik menunjukkan bahwa pada pengujian pH didapatkan nilai rata-rata yaitu kelompok basis (6,98), kelompok F1 (6,98), kelompok F2 (6,98), kelompok F3 (6,98). Uji daya sebar didapatkan nilai rata-rata yaitu kelompok basis (6,5 cm), kelompok F1 (5,77 cm), kelompok F2 (6,6 cm), kelompok F3 (6,6). Uji viskositas didapatkan nilai rata-rata yaitu kelompok basis (304,56 cps), kelompok F1 (302,73 cps), kelompok F2 (311,06 cps), kelompok F3 (312,06 cps), hasil uji aktivitas antibakteri didapatkan rata-rata hasil yaitu kelompok kontrol negatif (0 cm), kelompok kontrol positif (18 cm), kelompok F1 (14,6 cm), kelompok F2 (20,63 cm), kelompok F3 (25,46 cm). Kesimpulan : Kesimpulan penelitian ini adalah sediaan krim ekstrak daun kelor 5% mempengaruhi aktivitas antibakteri secara lemah, 10% secara sedang, 15% secara kuat dan semua sediaan krim memenuhi persyaratan uji sifat fisik.
Penambahan Vitamin A Meningkatkan Kapasitas Antioksidan Air Kelapa Muda : Studi Eksperimental pada Tikus yang dipapar Asap Rokok Stefani Harum Sari; Ratnawati; Joko Wahyu Wibowo
Indonesian Journal of Medical and Pharmaceutical Science Vol. 1 No. 1 (2022)
Publisher : Sultan Agung Islamic University of Semarang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30659/ijmps.v1i1.6

Abstract

Latar belakang: Stress oksidatif merupakan mekanisme jejas sel akibat paparan asap rokok. Suplementasi antioksidan berupa bahan makanan yang mengandung bioaktif maupun mikronutrien diharapkan mampu mencegah kerusakan sel dan memperbaiki kerusakan pada tingkat seluler. Vitamin A dan air kelapa muda berpotensi sebagai antioksidan untuk menurunkan tingkat stres oksidatif. Penelitian ini bertujuan untuk mengetahui kapasitas antioksidan kombinasi vitamin A dan air kelapa muda dalam menurunkan tingkat stres oksidatif akibat paparan asap rokok. Metode: Penelitian eksperimental dengan desain post test only control group, jumlah subyek penelitian 24 ekor tikus wistar jantan yang dibagi menjadi 4 kelompok secara acak. Kelompok 1 : pakan standar, kelompok 2 : pakan standar + paparan asap rokok, kelompok 3 : pakan standar + paparan asap rokok + air kelapa muda 8mL/ekor/hari, dan kelompok 4 mendapat pakan standar + paparan asap rokok+ air kelapa muda 8 mL/ ekor/hari+ vitamin A 108 IU/200 gBB/hari, Jenis pakan standar AD II sebanyak 20 g/ ekor/ hari, minum ad libitum. Lama penelitian 14 hari. Pemeriksaan kadar MDA dengan metode TBARS. Hasil: Rerata kadar MDA ( nmol/mL) kel. 1: 1,54 ± 0,21, kel. 2 : 9,77 ± 0,32, kel. 3: 3,77 ± 0,13, dan kel 4: 2,29 ± 0,34, setelah dilakukan uji anova didapatkan nilai p= 0,001. Kesimpulan: Terdapat perbedaan yang signifikan rerata kadar MDA kelompok tikus yang mendapat vitamin A dan air kelapa muda dibandingkan kelompok yang hanya air kelapa muda.
Edukasi Penggunaan Obat Saat Bulan Puasa Di Tinjau Secara Syariah Pada Pasien Skizoprenia Di Soerojo Hospital Magelang Farroh Bintang Sabiti; Sari Febriliani; Noor Wildiati Magfirah
Indonesian Journal of Medical and Pharmaceutical Science Vol. 1 No. 2 (2022)
Publisher : Sultan Agung Islamic University of Semarang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30659/ijmps.v1i2.60

Abstract

Background: Schizophrenia is a chronic disorder that often relapses or is characterized by delusions, hallucinations, confusion, and strange thoughts, abnormal motor behavior and negative symptoms. In overcoming mental disorders, the role of religion is important based on the verses of the Qur'an and the Sunnah of the Prophet. So that treatment may not only be cured by taking medicine but also by getting closer to the healer. The purpose of this study was to determine the effect of education on how to take medicine according to sharia in schizophrenic patients in hospitals in Magelang. Methods: This research is a type of qualitative descriptive research. Data collection in this study was carried out in February-March 2022. This study used a questionnaire as a data collection instrument and information delivery media using leaflets. Result & Conclusion: Characteristics of schizophrenic patients are mostly male (60%) with an age range of 15-18 years (73%) and there is an influence of understanding between before and after being given education about taking medication according to sharia in schizophrenia patients.
Analisis Label Halal pada Nama Dagang Obat Tablet Melalui Pengamatan pada Kemasan Sekunder terkait Jaminan Produk Halal di RSI Sultan Agung Semarang Aditya Dwi Meilani; Suwaldi Martodihardjo; Ida Ayu Ariessanti
Indonesian Journal of Medical and Pharmaceutical Science Vol. 1 No. 2 (2022)
Publisher : Sultan Agung Islamic University of Semarang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30659/ijmps.v1i2.82

Abstract

Background: Drug is a substance or mixture of materials used to prevent disease, treat, assist in diagnosis, render infertile or make muscles weak during surgery. The halal medicinal products in the manufacturing process, especially in the manufacturing of tablet drugs, must be free from ingredients containing pork and alcohol. In addition, tablet drugs can be said to be halal if in the production process it is proven that they are free from the critical point of halal medicinal ingredients. The purpose of this study was to find out how many trade names of tablet drugs were distributed by the Sultan Agung Islamic Hospital which included halal labels on the secondary packaging and the critical point of the halal tablet drugs. Methods: This study used an observational descriptive design. Data was collected by observing the secondary packaging of the Tablet Drug Trade Names found in the Hospital Pharmacy Logistics as many as 125 items of tablet drug trade names. The data is processed using tables and calculated the percentage of halal labels that have been listed as well as seeing the critical point of halal for drugs that have not been labeled halal. Results: The results of this study indicate that the inclusion of halal labels distributed by the Sultan Agung Islamic Hospital as many as 21 tablet drug items (16.8%) of the 125 tablet drug items have been labeled with a halal label and the rest have not included a halal label.Conclusion: Some of tablet drugs that are distributed by the Sultan Agung Islamic Hospital are not halal labelled, but still classified as halal drugs based on their composition and have been registered with BPOM.
The Effect of Halal Labelling of Medicine on Customer’s Purchase Interest at Karunia Sehat Baru Pharmaceutical Semarang Islina Dewi Purnami; Agustina Sawitri; Ulfa Ulli Ummaya
Indonesian Journal of Medical and Pharmaceutical Science Vol. 1 No. 2 (2022)
Publisher : Sultan Agung Islamic University of Semarang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30659/ijmps.v1i2.86

Abstract

Background: Halal labeling is the inclusion of halal writing or statements on product packaging to indicate that the product in question has the status of a halal product. The purpose of this study was to determine the effect of halal labeling on drugs on customer buying interest at the Karunia Sehat pharmacy in Semarang. Methods: The population in this study were all customers who came to the gift health pharmacy, and the number of samples needed was 96 respondents. Data was collected by distributing questionnaires directly to customers using a linkert scale and then scoring. Results: Based on data analysis, halal labeling on medicinal products are "very influential" on customer buying interest with a percentage of 71.9% which is in the 41-50 score category. Conclusion: halal labeling on medicinal can affect on customer’s purchase interest at Karunia Sehat Baru Pharmaceutical Semarang.
Gambaran Pengetahuan dan Perilaku Dagusibu Analgesik Topikal di Apotek Karunia Sehat Baru Atma Rulin Dewi Nugrahaini; Agustina Sawitri; Sandra Thertianing Susilo
Indonesian Journal of Medical and Pharmaceutical Science Vol. 1 No. 2 (2022)
Publisher : Sultan Agung Islamic University of Semarang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30659/ijmps.v1i2.87

Abstract

Latar belakang: Pengetahuan dan perilaku DAGUSIBU merupakan penerapan yang penting dalam kehidupan. DAGUSIBU yang diterapkan secara tepat akan menghindari dari penyalahgunaan penggunaan obat. Tujuan dilakukan penelitin tersebut guna untuj mengetahui gambaran pengetahuan dan perilaku masyarakat terkait DAGUSIBU analgetik topikal di lingkungan Apotek Karunia Sehat Baru. Metode: Penelitian dilakukan dengan penyebaran kuisioner dan diisi oleh masyarakat yang membeli obat analgetik topikal dan dianalisisa menggunakan analisa deskriptif untuk mengetahui persentase pengetahuan dan perilaku masyarakat. Hasil: Berdasarkan hasil jawaban kuesioner terhadap 30 responden, terkait penerapan atau pengaplikasian obat dinilai masih kurang (pola cuci tangan, penyimpanan, batas penggunaan obat analgetik dan cara membuang obat analgetic tipikal). Kesimpulan: Pengetahuan masyarakat tentang DAGUSIBU obat analgesik topikal nyeri otot lengan sudah baik namun dalam penginterpresntasi atau penerapannya masih tergolong rendah.
Pengaruh Pemberian Vitamin C Dosis Tinggi Terhadap Kadar Tumor Necrosis Faktor Alfa Pada Aktivitas Fisik Berat: Studi Eksperimental Pada Tikus Galur Wistar Jantan Reza Adityas Trisnadi; Angga Pria Sundawa
Indonesian Journal of Medical and Pharmaceutical Science Vol. 1 No. 2 (2022)
Publisher : Sultan Agung Islamic University of Semarang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30659/ijmps.v1i2.90

Abstract

ABSTRACT Strenuous physical activity will cause fatigue in athletes so it will be easier to experience infection. Strenuous physical activity will cause fatigue in athletes so it will be easier to experience infection. This condition in its prevention requires exogenous antioxidants such as vitamin C that reduce ros production. Vitamin C acts as a companion factor in several enzymatic reactions in the body and can boost components of the immune system so that it is expected to lower TNF-α levels. This type of research is an experimental laboratory with a post test only control group design approach using animals to try male white rats with malnutrition conditions that meet the criteria of inclusion and exclusion. The study plan was conducted for ± 22 days. The results of this study are expected to develop the use of high-dose vitamin C as an antioxidant to improve immune function or the immune system for the health of the body. Administering vitamin C at doses of 18 mg / ml / day and 36 mg / ml / day can reduce the amount of TNF-α in male rats who were given heavy physical activity.

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