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Dwi Endah Kusumawati
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INDONESIA
Indonesian Journal of Medical and Pharmaceutical Science
Published by Universitas Islam Sultan Agung
ISSN : -     EISSN : 28096576     DOI : -
Core Subject : Health, Science,
Chemistry Health Professions Immunology & microbiology Medicine & Pharmacology Public Health
This journal accepts and publishes academic articles focusing on theory, methods, and applications in: 1) Pharmaceutical science 2) Biomedical science 3) Herbal medicine 4) Clinical pharmacy 5) Drug discovery
Arjuna Subject : Pharmacology, Toxicology and Pharmaceutics - Pharmacology, Toxicology and Pharmaceutics (Lain-Lain)
Articles 52 Documents
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Pengaruh Konsentrasi PVA Terhadap Aktivitas Antioksidan Dan Sifat Fisik Masker Gel Peel Off Ekstrak Etanolik Daun Putri Malu (Mimosa pudica L) Krisya, Otta Ganes; Januarti, Ika Buana; Susmayanti, Windi
Indonesian Journal of Medical and Pharmaceutical Science Vol. 2 No. 1 (2023)
Publisher : Sultan Agung Islamic University of Semarang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30659/ijmps.v2i1.91

Abstract

Background: The leaves of Putri malu (Mimosa pudica L.) contain flavonoid compounds which act as antioxidants to prevent and reduce the effects of free radicals on the skin. The potency of this ingredient is formulated into a peel-off mask with a PVA gel base because it can help penetrate the active substance into the skin by forming a strong and plastic film that provides good contact between the drug and the skin. The purpose of this study was to determine the effect of PVA concentration on the physical properties and antioxidant activity of the Mimosa Pudica L. ethanolic extract peel-off gel mask. Methods: The leaves of Putri malu were extracted by maceration using 70% ethanol and then peel-off mask preparations were made with PVA concentrations of 8%, 10% and 12%. The masks were tested for physical properties including organoleptic tests, pH strength tests, viscosity and dry time tests as well as antioxidant activity. The data obtained was then analyzed using One Way ANOVA and Kruskall Wallis. Results: EEDPM Peel-Off Mask formula 1 produced an IC50 of 5.505 μg/ml, formula 2 1.088 μg/ml and formula 3 0.606 μg/ml which means that the three formulas have strong antioxidant activity. Conclusion: The higher the concentration of PVA in the ekstrak etanolik daun putri malu (EEDPM) peel-off gel mask, the stronger the antioxidant activity.
Kepuasan Konsumen Terhadap Kualitas Pelayanan Di Apotek Karunia Sehat Baru Berdasarkan Nilai-Nilai Syariah Fathnin, Fildza Huwaina; Sunandari, Agustina; Mumpuni, Wanda
Indonesian Journal of Medical and Pharmaceutical Science Vol. 2 No. 1 (2023)
Publisher : Sultan Agung Islamic University of Semarang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30659/ijmps.v2i1.95

Abstract

Background: Public health can be maintained and improved by providing good pharmaceutical services. Pharmaceutical services are currently required to change from focusing on products to focusing on patients. Islam emphasizes a quality service, namely the existence of a sense of satisfaction received by others because of the services provided. Based on this background, this study aim to conduct research on consumer satisfaction with the quality of service at the Karunia Sehat Baru Pharmacy based on sharia values. Methods: This type of research is descriptive observational with prospective data collection. The research was conducted at Karunia Sehat Baru Pharmacy. The subjects of this research were 30 consumers of Karunia Sehat Baru Pharmacy using purposive sampling technique. Data collection uses a questionnaire which is composed of 5 aspects, reliability, responsiveness, assurance, empathy, and tangible, on the basis of shidiq, amanah, tabligh, fatonah, which are tested for validity and reliability. Results: Consumer satisfaction with services at the Karunia Sehat Baru Pharmacy based on sharia values obtained an average index value of 97.98%, on the assurance dimension of 97.32%, the responsiveness dimension is 97.3%, the empathy dimension is 94.66%, and the tangibles dimension is 96.66%. Conclusion: The average level of satisfaction of respondents is included in the high category. These results provide input to the Karunia Sehat Baru Pharmacy to continue to maintain services so that consumers continue to get satisfaction, which can be in the form of making standards related to sharia values.
Analisis Efektivitas Biaya Terapi Enoxaparin dan Fondaparinux Pada Pasien Jantung N-STEMI Rawat Inap di RSD K.R.M.T. Wongsonegoro Purnami, Islina Dewi; Nugrahaeni, Atma Rulin Dewi; Khasanah, Ulfatun
Indonesian Journal of Medical and Pharmaceutical Science Vol. 2 No. 1 (2023)
Publisher : Sultan Agung Islamic University of Semarang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30659/ijmps.v2i1.114

Abstract

Background: N-STEMI heart disease in the community can provide a significant health and economic burden so that it can affect the quality of patient health. Enoxaparin and fondaparinux are often given to inpatients to overcome this problem because of the consideration between efficacy and safety of using drugs, one of which is the risk of patient bleeding. This study aim to determine the cost effectiveness of enoxaparin therapy and fondaparinux in the treatment of N-STEMI cardiac patients at RSD K.R.M.T. Wongsonegoro. Methods: This study is a descriptive observational method using a retrospective data collection from secondary data from the patient's medical record and the cost of care and treatment of patients during hospitalization. Processing of data in the form of numbers using Microsoft Excel then the data is processed according to the ACER and ICER calculation formulas. Results: The results show that compared to enoxaparin, fondaparinux is a cost-saving strategy (lower cost with slightly higher effectiveness). Fondaparinux is the most cost effective treatment for N-STEMI heart patients at RSD K.R.M.T. Wongsonegoro. Conclusion: Fondaparinux should be considered as a cost-effective alternative when compared to enoxaparin for inpatient N-STEMI cardiac patients at RSD K.R.M.T. Wongsonegoro based on length of hospitalization and duration of therapy, especially in the era of limited health resources.
Penerapan Penggunaan Antibiotik Bersertifikasi Halal Pada Pasien Anak Dengan Diare Akut Di RSD K.R.M.T Wongsonegoro Purnami, Islina Dewi; Nugrahaeini, Atma Rulin Dewi; Aprilla, Trifani
Indonesian Journal of Medical and Pharmaceutical Science Vol. 2 No. 1 (2023)
Publisher : Sultan Agung Islamic University of Semarang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30659/ijmps.v2i1.121

Abstract

Background : The use of antibiotics in accordance with the antibiotic resistance control program in pediatric patients with acute diarrhea and halal  certification on antibiotics. The purpose of this study was to known the implementation of halal certification antibiotics according to antibiotic resistance control program in pediatric patients with acute diarrhea at RSD K.R.M.T Wongsonegoro. Methods: The research method used was a retrospective descriptive approach by collecting data from medical records in pediatric patients with acut diarrhea. The population in this study were pediatric patients with acute diarrhea who were hospitalzed at RSD K.R.M.T Wongsonegoro, with inclusion criteria being pediatric patients diagnosed with acute diarrhea in inpatient care. Data taken from medical records include: age, gender, name of antibiotik, route of administration, then the use of antibiotic is calculated by the DDD (Defined Daily Dose/100 patient-days) formula, for halal certification of antibiotics through the MUI website  then calculate the percentage. Results: the number of  antibiotic used  in the treatment of acute diarrhea in children 36 pediatric patients ware ceftriaxone antibiotic as much as 24.57, Cefotaxime  5.47, oral  metronidazole 4.52,   amoxicillin 1.31, parenteral metronidazole 1.27 and  0,1 cefixme either orally or parenterally. While the percentage of antibiotics that have halal certification is 100%. Conclusion: Antibiotic with the highest use was cefotaxime 5.57 while the lowest was cefixime 0.1. for all antibiotics in the RSD K.R.M.T Wongsonegoro, they have been certified halal.   Keywords: Acute Diarrhea; Antibiotic; Halal Certification; Pediatric Patient; Resistance
A Study A Study of Female Suffered from HIV Wasting Syndrome and Pulmonary Tuberculosis Rachmatullah, Tri Ferry
Indonesian Journal of Medical and Pharmaceutical Science Vol. 2 No. 1 (2023)
Publisher : Sultan Agung Islamic University of Semarang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30659/ijmps.v2i1.123

Abstract

Background: Tuberculosis is the most often secondary infection of people living with HIV / AIDS. The tuberculosis co- infection with HIV will increase the risk of death. The purpose of this study was to understand the management of patient with HIV wasting syndrome and tuberculosis. Methods : A 45 years old female with HIV AIDS which being treated with ARV for 6 months, admitted to hospital with general weakness which was continuously progressive in three weeks. She felt fatigue and only lying on her bed for almost 2 month after she was hospitalized because of CNS infection. Sometimes there were fever, mild cough and vomitting. The general condition was weak, body mass index was 14.4 kg/m2 (underweight) and she got a nasogastrictube. Result: The laboratory finding showed anaemia ( 8,1 g/dl), hypokalemia (2,4 mmol/L), hypoproteinemia (4,9 g/dl), hypoalbuminemia (2,1 g/dl) and elevated of liver function test (AST 61 U/L, ALP 155 U/L), GGT 206 U/L). CD 4 count 34 cells / mm3  (410-1590 cells / mm3) and viral load detected 694.648 copies / ml. The chest X ray showed some infiltrate due to tuberculosis that has been diagnosed and treated earlier. Patientwere treated with anti retro viral, anti tuberculosis, red cell transfusion, albumin transfusion, physiotherapy, occupational therapy and adequate nutritional management. The condition of the patient was getting better on several follow up and she was permitted to discharged from hospital. Conclusion : Patient with 4th Stadium of HIV AIDS required comprehensive and multidiciplinary management to improve their health condition.
LAKI-LAKI 40 TAHUN DENGAN GAMBARAN USG ADENOMYOMATOSUS GALDBLADDER Widyastuti, Retno; Pramana, Triyanta Yuli
Indonesian Journal of Medical and Pharmaceutical Science Vol. 2 No. 2 (2023)
Publisher : Sultan Agung Islamic University of Semarang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30659/ijmps.v2i2.126

Abstract

Background: Adenomyomatosus gallbladder (GA) is a benign change of the gallbladder wall characterized by excessive epithelial proliferation associated with hyperplasia of the muscularis propria. This situation causes thickening of the gallbladder, so that the gallbladder comet tail artifact appears on an abdominal ultrasound examination. Methods: A 40-year-old man with complaints of right upper quadrant abdominal pain that is colic and recurrent. The patient was hospitalized twice within a week with the same complaint. Ultrasound examination of the patient's lawsuit against GA. The differential diagnosis of this case is chronic cholecystitis and cholesterosis, as seen from complaints of right quadrant abdominal pain and comet tail ultrasound images. Results: Cholecystectomy in patients is indicated for therapy and histopathological diagnosis. The results of histopathological examination obtained a picture that pointed to chronic cholecystitis. Conclusion: Diagnosis by histopathology is necessary in patients with ultrasound images of comet tail artifacts in the gallbladder to determine the patient's treatment and prognosis.
Pengaruh Pemberian Obat Asam Folat, Eritropoietin dan Kombinasi Asam Folat Eritropoietin dalam Meningkatkan Hemoglobin pada Pasien Hemodialisa di RSUD dr. Gunawan Mangunkusumo Purnami, Islina Dewi; Indriani, Yonanda Pratiwi; Susilowati, Dwi Retna
Indonesian Journal of Medical and Pharmaceutical Science Vol. 3 No. 1 (2024)
Publisher : Sultan Agung Islamic University of Semarang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30659/ijmps.v3i1.136

Abstract

Background: Anemia is a decrease in the total amount of hemoglobin or the number of red blood cells which causes insufficient oxygen supply to meet the body's physiological needs. This study aim to determine the effect of administration of folic acid, erythropoietin (hemapo) and erythropoietin folic acid combinations in increasing hb in hemodialysis patients at RSUD dr. Gunawan Mangunkusumo. Methods: This research is a non-experimental study using a cross-sectional design. Data collection was carried out retrospectively using medical records taken at the medical record unit which received treatment therapy with folic acid, erythropoietin and erythropoietin folate combination in outpatient hemodialysis patients. The sampling technique was carried out by purposive sampling technique. Data obtained during the study were analyzed using the Paired T-test (p-Value = <0.05). Results: Based on the Paired T-Test analysis, it is known that the p-Value = 0.001, this indicates that there is a significant difference in changes in hemoglobin levels before and after consuming folic acid, erythropoietin (hemapo), and the combination of increased Hb in hemodialysis patients at RSUD dr. Gunawan Mangunkusumo. Conclusion: The results of research that has been conducted usingOthe Paired T-Test show that there is a significant difference in changes in hemoglobin levels before and after consuming folic acid, erythropoietin (hemapo), and the combination in increasing Hb in patients at RSUD dr. Gunawan Mangunkusumo.
Formulasi Sediaan Face Mist Halal Ekstrak Air Putik Bunga Saffron (Crocus Sativus L.) Azmi Rahmadani; Priyagustin, Vira Risti; Roffada, Rizal
Indonesian Journal of Medical and Pharmaceutical Science Vol. 2 No. 2 (2023)
Publisher : Sultan Agung Islamic University of Semarang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30659/ijmps.v2i2.144

Abstract

Background: Face mist is a freshener that serves to refresh the skin. Saffron (Crocus sativus L.) was chosen as the active ingredient because it contains crocin, pirocrocin, and safranal. The phenolic and carotenoid compounds present in saffron are the most important sources of antioxidant activity. This study aims to formulate face mist halal of saffron flower extract. Methods: Saffron were extracted by maceration method using aquadest. Face mist with different extract concentration (F1: 0,7%, F2: 0,8%, and F3: 1%) was made with some additional additives. Identification of product halalness is studied based on list issued by Indonesian Ulama Council. Several characteristic tests have been carried out such as organoleptic test, pH, spray spreadability test, spray condition test, and dry time test. Results: In general, the results of halal identification found that all materials used in this study were halal. Physical characteristics test show that F1, F2, and F3 meet the requirements of good face mist where F3 has better dry time. Conclusion: Formulation 3 (F3) was the best formulation found in this study with the best organoleptic conditions, pH, spray power, dispersion, and dry time.
Peran Label Halal dalam Keputusan Konsumen Memilih Obat : Studi Observasional di Apotek Enggal Saras Ungaran Hussaana, Atina; Azida, Nining Farrikh; Marisa, Ana; Sholikhah, Anisatus
Indonesian Journal of Medical and Pharmaceutical Science Vol. 2 No. 2 (2023)
Publisher : Sultan Agung Islamic University of Semarang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30659/ijmps.v2i2.146

Abstract

Background: Islam has clear rules about halal products. For a Muslim, consuming halal products is a form of devotion to Allah SWT. The concept of halal and haram is the main point in people's consumption patterns. Like consuming food, consuming medicine must also be halal. This study was designed to learn about the proportion of halal-labeled drugs in Apotek Enggal Saras Ungaran and the influence of halal labels on consumer decisions to choose medicines. Methods: The research method uses a direct survey. The questionnaire was addressed to buyers at the Apotek Enggal Saras Ungaran who bought halal-labeled drugs and those not labeled as halal to determine the respondent's interest in halal-labeled products. Data collection is done by grouping the data according to the criteria and calculating the percentage of each group. Results: The use of halal-labeled drugs and drugs not labeled halal are 60% and 40%, respectively. Conclusion: Muslim consumers prefer halal products to those that are not labeled halal. Factors that determine community decision-making in choosing halal-labeled drugs at Apotek Enggal Saras Ungaran include knowledge of halal labels, price affordability, product evaluation, fulfillment of halal product needs, and alternatives in decisions to use halal drugs.
Evaluasi Sifat Fisik Sediaan Sabun Cair Ekstrak Bunga Telang (Clitoria ternate) Kusumawati, Dwi Endah; Puspitasari, Rega
Indonesian Journal of Medical and Pharmaceutical Science Vol. 2 No. 2 (2023)
Publisher : Sultan Agung Islamic University of Semarang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30659/ijmps.v2i2.147

Abstract

Background: Antiseptic liquid soap is increasingly popular with the public. The antibacterial substance that is usually contained in antiseptic liquid soap is triclosan, which when used in the long term can disrupt the balance of the normal flora on the skin, so natural ingredients are needed to replace the use of triclosan. One of the natural ingredients that can be used is butterfly pea. The aim of the study was to evaluate the physical properties of the butterfly pea liquid soap (organoleptic, pH, specific gravity, viscosity and foam stability) in accordance with the requirements listed in the SNI for liquid soap. Methods: This study is an analytical experiment, namely testing and analyzing the characteristics of butterfly pea liquid soap which consists of: organoleptic (consistency, color, aroma), pH, viscosity, and foam stability. Results: Hand washing liquid soap with butterfly pea flower extract complies with SNI requirements, with details: purple in color with slightly thick consistency, pH 4.5 – 5 , specific gravity 1.02 – 1.03 g/mL, viscosity 3456.33 – 6375.33 cP with foam stability of 93%. Conclusion: The physical characteristics of liquid hand washing soap with the active ingredient of butterfly pea flower extract comply with the requirements of SNI and have a purple color due to the presence of anthocyanin.

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