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Nanang Yunarto
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Pusat Penelitian dan Pengembangan Biomedis dan Teknologi Dasar Kesehatan Kementerian Kesehatan RI Jl. Percetakan Negara No. 23 - Jakarta 10560
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INDONESIA
Jurnal Kefarmasian Indonesia
Published by Pusat Penelitian dan Pengembangan Biomedis dan Teknologi Dasar Kesehatan
ISSN : 2085675X     EISSN : 23548770     DOI : -
Core Subject : Health, Science,
Chemistry Medicine & Pharmacology
Pharmaceutical Technology, Pharmacology, Pharmaceutical Chemistry, Traditional Medicines, and Pharmaceutical Care.
Arjuna Subject : Pharmacology, Toxicology and Pharmaceutics - Pharmacology, Toxicology and Pharmaceutics (Lain-Lain)
Articles 5 Documents
 1 
Search results for , issue "VOLUME 1, NOMOR 3, 2009" : 5 Documents clear
Efek Mutagenik Ekstrak Etanol Daun Kembang Sungsang (Gloriosa superba L.) Sundari, Dian; Pudjiastuti, Pudjiastuti
Jurnal Kefarmasian Indonesia VOLUME 1, NOMOR 3, 2009
Publisher : Pusat Penelitian dan Pengembangan Biomedis dan Teknologi Dasar Kesehatan

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22435/jki.v1i3.2848

Abstract

Eflicacy of a plant can be caused by chemical compounds contain, on the other hand can cause toxic eflects. Toxic ejfects of chemicals can be defined as the potential of chemicals to poison the bodies of people who are exposed kembang sungsang (Gloriosa superba Linn.) including Colchicaceae families. Plants used empirically for treatment of Gout, diuretic, rheumatism, etc. Mutagenicity is a test to determine the possibility of compounds are mutagens. To see if these plants have the effect of mutagens, mutagenicity tests performed 70% ethanol extract of the leaves Kembang sungsang. Mutagenicity studies conducted by the Ames method using five test bacterial strains that have been transferred are.‘ Salmonella typhimurium TA 98, TA 100, TA 1535, TA 1537 and Escherichia colt WP2uvrA with and without metabolic activator S-9. The dose tested was 125, Z50, 500, 1000, and 2000 ul /plate. As a negative control was DMSO solution of 100 ul /plate. The results showed that the mutagenic test 70% ethanol extract of leaves Kembang sztngsang. with the addition aktivator without the addition of S-9 did not have the eflect of mutagens.
Gambaran Kualitas Air Minum Di Jabodetabek Tahun 2007-2009 Alegantina, Sukmayati; Isnawati, Ani; Raini, Mariana
Jurnal Kefarmasian Indonesia VOLUME 1, NOMOR 3, 2009
Publisher : Pusat Penelitian dan Pengembangan Biomedis dan Teknologi Dasar Kesehatan

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22435/jki.v1i3.2849

Abstract

The greater the public awareness of health can be ascertained from the number of people who determined the water used for drinking water. Water determination is one of the programs in Pharmacy and Chemistry Laboratory in Center for Biomedic and Pharmacy. Ministry of Health. Water sample is determined chemically and physically based on the parameter requirements by the Regulation of Ministry of Health (Permenkes) No 907/Menkes/SK/V11/2002. The design of the study is cross-sectional, the samples are waters from Jakarta, Depok, Tangerang, Bekasi (Jabodetabek), and outside Jabodetabek. The water samples are obtained from people who requested to determine their drinking water during period 2007- 2008. The amount of the water samples are 1668. Water determination is done both physically and chemically. Physical water determinations are including odor, TDS (total of dissolved solids), flavour, temperature, turbidity, and colour. Chemical water determinations are Nitrit, Fer-rum, hardness, Chloride, Manganese, pH, Sulfate, Sulfide, and organic substances. Based on the results, the result shows that 27,5% of water determinations are not recommended to drink because it contained high concentration of Manganese /7,6 91), Ferrum (7,2 %), turbidity (2,4%) and colour (2,5 %). The ratio of the samples which is not recomended to drink towards total sample in one area of Tangerang is 52.0%. Based on sampling water depth >100 m, the ratio of the samples which is not recomended to drink towards the total sample that collectedfrom the depth >100 m sample is 64.2%.
Kajlan Upaya Pengembangan Ramuan Battra Di Kabupaten Kutai Kartanegara Widowati, Lucie; Murniwati, Murniwati
Jurnal Kefarmasian Indonesia VOLUME 1, NOMOR 3, 2009
Publisher : Pusat Penelitian dan Pengembangan Biomedis dan Teknologi Dasar Kesehatan

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22435/jki.v1i3.2850

Abstract

The growth of the number of Traditional Healers at Kutai Kartanegara Regency increases, including the Traditional Healer of remedies, using medicinal plants. The presence of herbs Traditonal Healers indirectly in improving helath and this condition needs to be proved by a survey to Traditional Healers with remedies of medicinal plant, using a questionnaire instrument. Traditoonal Healers profiles obtained from interviews using a questionnaire that describes Traditional Healers characteristics, source of knowledge, permission practices, place / space of practice, patient records etc. It is of concern is that almost all Traditional Healers not yet registered with the local Ministry of Health and have no record of the patient. While in the case of the medicinal plants used by Traditional Healers, problems that arise are very varied although for medicinal plants / complaints / same disease. Rationally number of medicinal plants, how making the right ingredients, dosage of medication use and how long to use these medicinal plants, needs to be studied to assure safety of use and provide the expected properties. The assessment results will be the direction of further development is still traditionally used or will be carried out research into herbal standardized, phytopharmaca,even into the drug with the specific active compounds, so that can be directed to the acquisition of patents. In the framework of guidance covering the above matters, suggested the existence of cooperation and coordination with the Faculty of Medicine Faculty of Pharmacy, or who are in the province of East Kalimantan.
Penyakit Peptik dan Misoprostol Raini, Mariana; Isnawati, Ani
Jurnal Kefarmasian Indonesia VOLUME 1, NOMOR 3, 2009
Publisher : Pusat Penelitian dan Pengembangan Biomedis dan Teknologi Dasar Kesehatan

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22435/jki.v1i3.2851

Abstract

Peptic mucus synthesize especially prostaglandine E2 and 12. Prostaglandine E2 and l2 can impede acid secrete and stimulate mucus and bicarbonate secretion. Misoprostol, a synthetic methyl ester analogue of prostaglandin is both a powerful inhibitor of gastric secretion and is able to protect the gastroduodenal mucosa from damage. Misoprostol and other prostaglandine derivatives can be alternative drug of peptic ulcer relapse because the metyl ester of prostaglandin exert an antisecretion and protective effects on peptic mucus. The clinical eflectiveness of misoprostol is comparable to cimethidin in short term treatment of peptic and duodenum ulcer as well as reducing duodenal ulcer relapse. Misoprostol may prevent gastrointestinal and peptic ulcer in long term treatment of Non Steroid Anti Inflamation Drug. The side eflect of misoprostol is cervix maturation and uterotonic. This article describe misoprostol eflecliveness on peptic and duodenum ulcer treatment.
Kajian Peraturan Perundang-Undangan Tentang Iklan Obat dan Peran Serta Masyarakat dalam Pengawasannya Supardi, Sudibyo
Jurnal Kefarmasian Indonesia VOLUME 1, NOMOR 3, 2009
Publisher : Pusat Penelitian dan Pengembangan Biomedis dan Teknologi Dasar Kesehatan

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22435/jki.v1i3.2852

Abstract

The problem of study is the drugs advertising control in print media and broadcast media have been done, but many of them deviated from the legislation. The aims of study are to describe of the legislation articles related to the drug advertising and the community participation in drug advertising control. Method of study is analysis secondary data of legislation articles related to the drug advertising and public participation. The Study based on the laws, government regulations, health ministers regulations, local regulations until a decision letters. The data analysis based on understanding article by article of legislation about the drug advertising. The results show that : 1. The drug advertising must be objective, complete and not misleading which published after approved by health ministry, 2. The drug advertising control is undertaken by The National Agency of Drug and Food Control. The cooperation with various organizations should be done to decrease deviating drug advertising from the legislation, 3. The Community participation in the drug advertising monitoring is in the complaint form to The National Agency of Drug and Food Control or the non government organizations related to drug advertising. The drug cortsumers if harmed by drug advertising can protest through the approach of administration punishment, the civil law, and the criminal law.

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