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Jurnal Farmasi Teknologi Sediaan dan Kosmetika (JFTSK)
Published by CV Jurnal Literasi Mandiri
ISSN : -     EISSN : 30632226     DOI : https://doi.org/10.70075/jftsk.v2i1.145
Core Subject : Health, Engineering,
Health Professions Industrial & Manufacturing Engineering Medicine & Pharmacology
Jurnal Farmasi Teknologi Sediaan dan Kosmetika (JFTSK) merupakan jurnal yang di rilis oleh Jurnal Literasi Mandiri (JLM). Jurnal ini menerima publikasi dari Dosen, Peneliti, Guru, Mahasiswa, Siswa dan Semua Kalangan yang ruang lingkup penelitiannya berfokus pada Teknologi Sediaan farmasi dan Kosmetika. Adapun penjabaran fokus Jurnal Farmasi Teknologi Sediaan dan Kosmetika yaitu 1. Pengembangan Teknologi Sediaan Farmasi 2. Pengembangan Sediaan Kosmetika 3. Pengembangan Teknologi Penghantaran obat Dengan adanya Jurnal ini diharapkan dapat membantu dalam penelusuran penelitian dan memperkaya literasi terkait Teknologi Sediaan dan Kosmetika.
Arjuna Subject : Pharmacology, Toxicology and Pharmaceutics - Pharmacology, Toxicology and Pharmaceutics (Lain-Lain)
Articles 41 Documents
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Preparation and Characterization of Moringa Leaf Extract in Ethosomal Vesicles with Variations in Phosphatidylcholine and Ethanol Concentrations Nur Utami Pobela; Robert Tungadi; Nurain Thomas; Juliyanty Akuba; Multiani S. Latif
Jurnal Farmasi Teknologi Sediaan dan Kosmetika Vol. 3 No. 2 (2026): Volume 3 Nomor 2 Tahun 2026
Publisher : Jurnal Literasi Mandiri

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.70075/jftsk.v3i2.24

Abstract

Moringa is a medicinal plant with antioxidant properties, and quercetin is one of the compounds considered to contribute to this activity. Quercetin is a hydrophobic compound classified as Biopharmaceutics Classification System (BCS) Class II, characterized by high permeability and low solubility. To overcome this limitation and improve the bioavailability of the active compound, the active compound can be encapsulated in a nanosized carrier system. Ethosomes are vesicular carrier systems suitable for lipophilic, hydrophilic, and amphiphilic compounds. This study aimed to prepare and characterize ethosomes containing Moringa leaf extract using different concentrations of phosphatidylcholine and ethanol. Three formulations were prepared: F1 containing 1% phosphatidylcholine and 20% ethanol, F2 containing 2% phosphatidylcholine and 30% ethanol, and F3 containing 3% phosphatidylcholine and 40% ethanol. Characterization using a Particle Size Analyzer (PSA) showed particle sizes of 202.3 nm, 185 nm, and 146.3 nm for F1, F2, and F3, respectively, with mean polydispersity index (PDI) values of 0.346, 0.293, and 0.196. The corresponding entrapment efficiencies were 36%, 35%, and 41%, respectively. F3 exhibited the most favorable characteristics, with the smallest particle size and the highest entrapment efficiency.

Page 5 of 5 | Total Record : 41

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