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Thrive Health Science Journal
ISSN : 30469430     EISSN : 30468647     DOI : https://doi.org/10.56566/thrive
Core Subject : Health,
THRIVE Health Science Journal (THSJ) publishes original research findings and review articles related to Public Health, Medicine and Sciences. Papers presented at recognized conferences may be considered for publication. THSJ is an Open Access Journal where readers have access to full text for free while authors are expected to pay to publish. The journal is published two times a year, namely in March and September. The language of the journal is English, and all manuscripts submitted for publication are subject to peer review by editors. Those manuscripts which are considered proper by editors are sent to at least two experts in the field. Those articles not accepted for publication will be returned to the author. The editorial board reserves the right to edit all manuscripts for clarity or structure, fit within the space available, and decide on editorial matters. All review processes are carried out using a Double-blind review method and are managed by the editorial board. This method keeps the identity of the reviewer confidential from the author. Any reviewer who is asked to review an article by the editor of the THRIVE Health Science Journal must comply with the Ethics for Reviewers. THRIVE Health Science Journal provides open access that can be read and downloaded for free to the public and will support the exchange of knowledge in science and humanity service. The copyright of the published article is held by the author and under license Creative Commons Attribution 4.0 International License
Articles 8 Documents
Search results for , issue "Vol. 2 No. 2 (2025): September" : 8 Documents clear
Global Perspectives on Drug Regulatory Bodies: Roles, Challenges, and Collaborative Frameworks Ahmed, Rashed
THRIVE Health Science Journal Vol. 2 No. 2 (2025): September
Publisher : Balai Publikasi Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.56566/thrive.v2i2.322

Abstract

The article "Comparison of Drug Regulatory Bodies: EMA, DGDA, ISO, WHO, TGA, MHRA, and FDA" presents a comprehensive analysis of global drug regulatory organizations, focusing on their roles, responsibilities, and impact on public health. The research delves into the historical development, operational frameworks, and collaborative efforts of these agencies to ensure the safety, efficacy, and quality of pharmaceutical products and medical devices. By incorporating methodologies such as literature review, comparative analysis, critical evaluation, and historical contextualization, the study identifies key similarities and differences among these organizations. The article also examines the critical role of pharmacists in these regulatory bodies, emphasizing their involvement in drug evaluation, pharmacovigilance, and policy development. Furthermore, the study explores the concepts of In-Process Quality Assurance (IPQA) and In-Process Quality Control (IPQC), illustrating their necessity even in the presence of established Quality Control (QC) and Quality Assurance (QA) departments. By addressing challenges such as long approval times, high compliance costs, regulatory inconsistencies, and limited resources in developing countries, the research underscores the importance of global collaboration and regional adaptation in drug regulation. The article concludes by advocating for strengthened regulatory systems, enhanced international cooperation, and balanced approaches to ensure the rational use of drugs and equitable access to quality medicines worldwide.
The Relationship between Screen Time and Speech and Language Development in 3-6 Years Children Annisa, Lale Hurun ‘In; Rukmana, Bq Fitrihan; Wahyudi, Iwan; Amrullah, Muhammad
THRIVE Health Science Journal Vol. 2 No. 2 (2025): September
Publisher : Balai Publikasi Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.56566/thrive.v2i2.330

Abstract

Screen time activity in children at developmental age has an important positive and negative influence. Currently, screen time has become a habit for children in their daily activities, so it is not uncommon to find children with high and excessive screen time habits. This can affect the growth and development of children in various aspects, one of which is speech and language development. This study aims to determine the relationship between screen time and speech and language development in children aged 3-6 years in Ketara Village. This research uses a cross-sectional method with a quantitative approach. The population in this study is 261 children aged 3-6 years. The sampling method in this study uses purposive sampling with a sample size of 72 children. The hypothesis analysis of this study uses chi-square analysis. The research results show that most respondents experience a high level of screen time habit, with 37 children (51.4%), and most children with speech and language development measurements using the DENVER II observation sheet, 42 (58.3%) children experience suspect development. The Spearman rank correlation test result obtained a Chi-Square value with a significance level of < 0.001 (p-value < 0.05), which means that Ha is accepted, so it is concluded that there is a significant relationship between Screen Time and Speech and Language Development in Children Aged 3-6 Years in Desa Ketara.
Clean Home, Healthy Family: Unveiling the Link Between Cleanliness and Health Trenggono, Aisha; Anisa, Isvi; Wahyudi, Zahwa; Khaerunnisa, Nabila; Achdiani, Yani; Ana, Ana
THRIVE Health Science Journal Vol. 2 No. 2 (2025): September
Publisher : Balai Publikasi Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.56566/thrive.v2i2.421

Abstract

This work aims to investigate how household cleanliness affects family health from multiple dimensions, including physical, mental, and social aspects. Using a literature study method, this article explores how a clean home environment contributes to disease prevention, emotional stability, and positive family interactions. Findings reveal that maintaining cleanliness such as proper waste disposal, access to clean water, hygienic food preparation, and organized living spaces plays a crucial role in reducing health risks and improving the quality of life. Physically, clean environments prevent infections and promote healthy routines. Mentally, tidy spaces lower stress levels and support emotional well-being by offering a sense of control and comfort. Socially, cleanliness encourages cooperation, respect, and bonding among family members. The results emphasize that cleanliness is not merely about appearance, but is fundamental to sustaining overall family wellness. This study concludes that a consistently clean and well-maintained household significantly enhances the physical, mental, and social health of its members, making it a critical component of family resilience and harmony
Antibacterial Activity Test of Ethanol Extract of Palm Leaves (Catharantus roseus) Against Staphylococcus aureus and Escherichia coli Bacteria Fitriana, Yuli; Iradhatullah, Sri Putriani; Sugara, Taufan Hari; Hendriyani, Irmatika; Nurbaety, Baiq; Faisal, Muhammad
THRIVE Health Science Journal Vol. 2 No. 2 (2025): September
Publisher : Balai Publikasi Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.56566/thrive.v2i2.424

Abstract

Ethanol extract of virgin palm leaves (Catharantus roseus) contains active compounds that have potential as natural antibacterial. This study aims to test the antibacterial activity of the extract against Staphylococcus aureus and Escherichia coli bacteria. The leaves of the tread are extracted using the maceration method with a 70% ethanol solvent. The extraction results showed a yield of 6.1% and the identification of compound content showed the presence of alkaloids, flavonoids, saponins, tannins, and phenols. The antibacterial test was carried out by disc diffusion method using concentrations of 60%, 80%, and 100%. Antibacterial activity was tested by calculating the resulting inhibition zones against both types of bacteria. The results showed that in Staphylococcus aureus bacteria, the concentration of 100% resulted in an inhibition zone of 11.66 mm which was classified as strong. In contrast, in Escherichia coli bacteria, the same concentration resulted in an inhibition zone of 2.66 mm which was in the weak category. This difference in effectiveness is due to the cell wall structure of gram-positive and gram-negative bacteria. The results of this study identified that ethanol extract of virgin leaves has a greater potential for gram-positive bacteria than gram-negative. The ethanol extract of virgin leaves demonstrated antibacterial activity against both Staphylococcus aureus and Escherichia coli, with stronger effects observed against S. aureus.
Prevalence of Malaria Among Children Under Five Years of Age in Miya Ward Ganjuwa Local Government From 2013-2017 Salisu, Umar Muhammad; Muhammad, Maimuna
THRIVE Health Science Journal Vol. 2 No. 2 (2025): September
Publisher : Balai Publikasi Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.56566/thrive.v2i2.442

Abstract

The study was conducted from 2013 to 2017 in Miya ward Ganjuwa local government, Bauchi state, to ascertain the incidence of malaria in children aged 0 to 5. The majority of patients, particularly those under five, who visit the health facility in the Miya Ward clinic have been found to have malaria.  This is demonstrated by their epidemiological record, which was acquired at the health facility during the research project. The study project is anticipated to be important for the residents of the Miya ward clinic, especially the children under five, as well as for the government and non-governmental organizations to have a better understanding of the issues that are currently being faced.  Male children are more likely than female children to contract malaria, according to the results of this study, which was conducted using a descriptive research design in which data was collected using a methodical approach and the characteristics of specific variables related to the study were explained. Additionally, it was found that malaria is usually quite common during the rainy season.  Finally, more study should be done to determine the frequency of malaria in children throughout the whole Miya Ganjuwa local government in Bauchi state
The Effect of Providing Education Through Video on the Level of Knowledge of Inhaler Use in Asthma Patients Hamdani, Ade Sukma; Anggita Putri, Zahwa
THRIVE Health Science Journal Vol. 2 No. 2 (2025): September
Publisher : Balai Publikasi Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.56566/thrive.v2i2.431

Abstract

Asthma is a heterogeneous lung disease that affects more than 300 million people. The most ideal dosage form for asthma therapy is via the inhalation route, namely with a device called an inhaler. This study aims to see the effect of providing education via video to outpatient asthma patients at the Praya Regional Hospital, Central Lombok, NTB Province. The Wilcoxon test was carried out to determine the significance of changes in knowledge and attitudes about asthma prevention before and after treatment at the 95% confidence level (ɑ=0.05). From the research results, it is known that 61.54% of the 13 respondents from asthma outpatients at Praya Regional Hospital were men, and 38.46% were women and were dominated by people aged >45 years. Patients admitted that their asthma complaints were caused by a history of allergies, as many as 61.54% were allergic to dust, followed by allergies to cold and food (seafood). The number of samples was limited so a chi-square test was carried out which then found a relationship between two variables, namely gender and length of inhaler use with the knowledge score on how to use the inhaler correctly which was marked with a significance value. <0.05.
The Impact of TikTok-Based Health Education on High School Students’ Knowledge of HIV/AIDS Mustika Budiarti, Baiq; Wahyudi, Iwan; Fitrihan Rukmana, Baiq
THRIVE Health Science Journal Vol. 2 No. 2 (2025): September
Publisher : Balai Publikasi Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.56566/thrive.v2i2.436

Abstract

HIV/AIDS is a disease that can cause a person's immune system to decline to the point of death. HIV/AIDS in adolescents is an important problem to pay attention to, considering the many behavioral problems adolescents are increasingly vulnerable to HIV/AIDS. The large number of HIV/AIDS cases among adolescents is caused by low adolescent knowledge. This study was conducted to determine the effect of TikTok-based health education on adolescents' knowledge about HIV/AIDS at SMA Negeri 2 Jonggat. The method used in this study is contingent with a pre-experimental design  using the one group pre – test – post – test approach. The number of respondents in this study is 40 people, with purposive sampling technique. The results of the Wilcoxon rank test showed  a P-value of 0.001 < 0.05 which means that there is an influence of TikTok-based health education on adolescents' knowledge about HIV/AIDS at SMA Negeri 2 Jonggat, it can be concluded that TikTok-based health education has a significant influence on adolescents’ knowledge about HIV/AIDS.
The Relationship of Screen Time to the Incidence of Speech Delay in Children Aged 2-5 Years Pebriana, Rauhil; Wahyudi, Iwan; Mastuty, Amalia
THRIVE Health Science Journal Vol. 2 No. 2 (2025): September
Publisher : Balai Publikasi Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.56566/thrive.v2i2.437

Abstract

: This study analyzes the relationship between screen time and the incidence of speech delay in children aged 2-5 years. The Alpha generation, which was born in 2010, is known as a smart generation because it grew up in the era of technology and the internet. However, excessive use of screen time can reduce social interaction and interfere with children's speech development. The method used was descriptive quantitative with a cross sectional approach, involving 60 respondents who were selected through purposive sampling and measured using questionnaires. The results showed that 19 respondents (52.8%) with high screen time intensity experienced speech delay, while 9 respondents (50.0%) with moderate intensity and 5 respondents (83.3%) with low intensity also experienced the same. The hypothesis test using Kendall's tau c yielded a p-value of 0.461 (p > 0.05), indicating no significant association between screen time and speech delay events. The conclusion of this study confirms that screen time does not have a significant effect on children's speech development in the region.

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