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All Journal Jurnal Biosains Pascasarjana Journal of Pharmaceutical (JOP) Journal of Community Empowerment Thrive Health Science Journal
Hendriyani, Irmatika
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Agriculture, Biological Sciences & Forestry Biochemistry, Genetics & Molecular Biology Dentistry Economics, Econometrics & Finance Education Health Professions Immunology & microbiology Languange, Linguistic, Communication & Media Medicine & Pharmacology Nursing Public Health Social Sciences Veterinary

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Antibacterial Activity Test of Ethanol Extract of Palm Leaves (Catharantus roseus) Against Staphylococcus aureus and Escherichia coli Bacteria Fitriana, Yuli; Iradhatullah, Sri Putriani; Sugara, Taufan Hari; Hendriyani, Irmatika; Nurbaety, Baiq; Faisal, Muhammad
THRIVE Health Science Journal Vol. 2 No. 2 (2025): September
Publisher : Balai Publikasi Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.56566/thrive.v2i2.424

Abstract

Ethanol extract of virgin palm leaves (Catharantus roseus) contains active compounds that have potential as natural antibacterial. This study aims to test the antibacterial activity of the extract against Staphylococcus aureus and Escherichia coli bacteria. The leaves of the tread are extracted using the maceration method with a 70% ethanol solvent. The extraction results showed a yield of 6.1% and the identification of compound content showed the presence of alkaloids, flavonoids, saponins, tannins, and phenols. The antibacterial test was carried out by disc diffusion method using concentrations of 60%, 80%, and 100%. Antibacterial activity was tested by calculating the resulting inhibition zones against both types of bacteria. The results showed that in Staphylococcus aureus bacteria, the concentration of 100% resulted in an inhibition zone of 11.66 mm which was classified as strong. In contrast, in Escherichia coli bacteria, the same concentration resulted in an inhibition zone of 2.66 mm which was in the weak category. This difference in effectiveness is due to the cell wall structure of gram-positive and gram-negative bacteria. The results of this study identified that ethanol extract of virgin leaves has a greater potential for gram-positive bacteria than gram-negative. The ethanol extract of virgin leaves demonstrated antibacterial activity against both Staphylococcus aureus and Escherichia coli, with stronger effects observed against S. aureus.
SASAMBO : SOSIALISASI REMAJA BEBAS NARKOBA DI SMAN 1 PRAYA Hendriyani, Irmatika; Hijriani, Nursela; Fitriana, Yuli; Faisal, Muhammad; Widodo, Ageng Ary
Journal of Community Empowerment Vol 4, No 2 (2025): September
Publisher : Universitas Muhammadiyah Mataram

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31764/jce.v4i2.32272

Abstract

ABSTRAK                                                                Penyalahgunaan narkoba di kalangan remaja merupakan isu serius yang mengancam masa depan generasi muda. Program “SASAMBO” (Sosialisasi Remaja Bebas Narkoba) hadir sebagai upaya edukatif untuk meningkatkan kesadaran dan pengetahuan siswa mengenai bahaya narkoba. Tujuan kegiatan pengabdian ini untuk meningkatkan pengetahuan siswa dalam pencegahan bebas narkoba. Kegiatan ini dilaksanakan di SMAN 1 Praya dengan melibatkan 25 siswa anggota Palang Merah Remaja (PMR), yang telah dilaksanakan pada 16 Mei 2025. Metode yang digunakan berupa edukasi interaktif, diskusi kelompok, dan evaluasi melalui pretest dan posttest. Hasil evaluasi menunjukkan adanya peningkatan signifikan dalam pengetahuan siswa setelah mengikuti kegiatan sosialisasi. Program ini tidak hanya memberikan informasi, tetapi juga membentuk sikap preventif terhadap penyalahgunaan narkoba. Dengan demikian, SASAMBO menjadi model edukasi yang potensial untuk diterapkan di sekolah-sekolah lain sebagai langkah strategis dalam pencegahan narkoba sejak dini.Kata kunci: narkoba; remaja; sosialisasi;pendidikan kesehatan, pencegahan ABSTRACTDrug abuse among adolescents is a serious issue that threatens the future of the younger generation. The "SASAMBO" (Socialization of Drug-Free Youth) program is presented as an educational effort to increase students' awareness and knowledge about the dangers of drugs. The purpose of this community service activity is to increase students' knowledge in preventing drug-free. This activity was carried out at SMAN 1 Praya with the involvement of 26 students who are members of the Youth Red Cross (PMR), which was implemented on May 16, 2025. The methods used were interactive education, group discussions, and evaluation through pretests and posttests. The evaluation results showed a significant increase in student knowledge after participating in the socialization activity. This program not only provides information, but also forms a preventive attitude towards drug abuse. Thus, SASAMBO is a potential educational model to be implemented in other schools as a strategic step in early drug prevention. Keywords: drugs; adolescents; awareness campaign; health education; prevention
Perbandingan Kadar Total Flavonoid Fraksi Air, Etil, Asetat, n-Heksana pada Daun Tanaman Apu-Apu (Pistia stratiotes L.) Menggunakan Spektrofotometri UV-Vis Hendriyani, Irmatika; Widodo, Ageng Ary; Fitriana, Yuli
JOURNAL OF PHARMACEUTICAL (JOP) Vol. 1 No. 2 (2023): Journal of Pharmaceutical (JOP)
Publisher : Lembaga Penelitian dan Pengabdian kepada Masyarakat (LPPM) UNIVERSITAS JENDERAL ACHMAD YANI YOGYAKARTA

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30989/jop.v1i2.1233

Abstract

Apu-apu (Pistia stratiotes L) merupakan tanaman yang tumbuh didaerah tropis dan tumbuh diatas permukaan air yang tenang ataupun mengalir relatif lambat contohnya seperti area pertanian. Umumnya para petani menganggap tanaman apu-apu (Pistia stratiotes L) sebagai hama atau gulma yang menyerap kandungan nutrisi tanaman disekitarnya. Tanaman apu-apu (Pistia stratotes L) dapat tumbuh liar didaerah rawa, sungai, danau atau genangan air, sehingga dianggap dapat menyebabkan kerusakan lingkungan. Hasil skrining fitokimia Ekstrak etanol daun tanaman apu-apu (Pistia stratiotes L.) pada fraksi air dan etil asetat mengandung senyawa flavonoid dilihat dari perubahan warna, sedangkan untuk fraksi n-Heksan tidak mengandung senyawa flavonoid, hal ini dibuktikan dengan uji sinoda perubahan warnayang dilihat. Pada perhitungan Kadar Total Flavonoid yakni fraksi air mengandung senyawa Flavonoid sebesar 0,914 mgQE dalam 10 mg ekstrak sampel, pada fraksi Etil asetat mengandung 1,205 mgQE dalam 10 mg ekstrak sampel.
IDENTIFICATION OF METABOLITE COMPOUNDS IN EXTRACT AND EXTRACT FRACTIONS OF MORINGA LEAVES (Moringa oleifera) USING THIN LAYER CHROMATOGRAPHY (TLC) METHOD Khairi, Widayatul; Safwan; Hendriyani, Irmatika
Jurnal Biosains Pascasarjana Vol. 27 No. 2 (2025): JURNAL BIOSAINS PASCASARJANA
Publisher : Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/jbp.v27i2.2025.175-182

Abstract

Moringa oleifera, known in Indonesia as "kelor," is often referred to as "the miracle tree" due to its natural nutritional and medicinal properties. Compounds found in Moringa leaf extract have been confirmed to include flavonoids. These compounds contain -OH groups attached to benzene rings, which contribute to their antioxidant, anti-inflammatory, and antimicrobial properties. The aim of this study was to identify secondary metabolites in Moringa leaves using the Thin Layer Chromatography (TLC) method. The results showed that flavonoids, tannins, alkaloids, and saponins were present in the ethyl acetate fraction, while tannins were found in both the extract and aqueous fraction. Additionally, steroids were detected in the n-hexane fraction. In conclusion, Moringa oleifera contains secondary metabolite compounds.
Co-Authors Baiq Nurbaety Iradhatullah, Sri Putriani Khairi, Widayatul Muhammad Faisal NURSELA HIJRIANI Safwan Taufan Hari Sugara Widodo, Ageng Ary Yuli Fitriana