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All Journal Jurnal Farmasi Sains dan Komunitas SELAPARANG: Jurnal Pengabdian Masyarakat Berkemajuan Journal of Pharmaceutical (JOP) Medika: Jurnal Ilmiah Kesehatan Journal of Community Empowerment Thrive Health Science Journal
Muhammad Faisal
Universitas Muhammadiyah Mataram
Agriculture, Biological Sciences & Forestry Computer Science & IT Control & Systems Engineering Economics, Econometrics & Finance Education Engineering Environmental Science Health Professions Immunology & microbiology Languange, Linguistic, Communication & Media Law, Crime, Criminology & Criminal Justice Medicine & Pharmacology Nursing Public Health Social Sciences Veterinary Other

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Nanoemulgel Formulation of Eleutherine palmifolia Onion Bulb Extract and Its Effectiveness in Wound Healing Faisal, Muhammad; Chabib, Lutfi; Dewi, Melynia Sintha; Gani, Michael Raharja; Dwiastuti, Rini
Jurnal Farmasi Sains dan Komunitas (Journal of Pharmaceutical Sciences and Community) Vol 21, No 2 (2024)
Publisher : Sanata Dharma University

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24071/jpsc.007454

Abstract

Eleutherine palmifolia onion, an indigenous medicinal plant from Borneo, is empirically applied to treat wound healing. The objective of this study is to formulate its extract and assess its in vivo wound healing activity. Eleutherine palmifolia onion was extracted with a 96% ethanol solvent. The extract of the Dayak onion bulb was then formulated into a nanoemulsion by applying the DOE method of 2-level factorial design. Four nanoemulsion formulations were further analyzed to obtain the optimal formulation. The particle size analysis and % transmittance was performed using a particle size analyzer and an ultraviolet-visible spectrophotometer. Furthermore, the data were analyzed using the Minitab 19 application with the DOE factorial design method. The three nanoemulgel formulations containing 2.5, 5.0, and 7.5% extract were further investigated for wound healing efficacy in rats. The duration of wound closure was analyzed using paired t-tests. The best nanoemulsion formulation was made with 22.5 mL of Tween 80 and 2 mL of isopropyl myristate oil. This produced particles that were 12.13 nm in size and a 99.12% transmittance rate. Wound length measurements were taken daily for 15 days. The statistical test results of p0.05 indicate that the nanoemulgel of the extract has significant activity in wound healing. The optimal nanoemulsion formula is formula A, and the effective dose of Dayak onion extract nanoemulgel is 5% and 7.5% concentrations, with a wound healing time of 13 days.
EDUKASI PENGENALAN JENIS TANAMAN HERBAL KEPADA MASYARAKAT DI DESA KEKERI LOMBOK BARAT Hendriyani, Irmatika; fitriana, yuli; wahid, abdul rahman; nopitasari, baiq leny; pradiningsih, anna; nurbaety, baiq; hijriani, nursela; faisal, muhammad; puspitasari, sintha; anjani, baiq lenysia puspita; rahmawati, cyntiya; khairi, widayatul; safwan, Safwan
Journal of Community Empowerment Vol 4, No 1 (2025): Juni
Publisher : Universitas Muhammadiyah Mataram

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31764/jce.v4i1.30246

Abstract

ABSTRAK                                                                            Tanaman herbal memiliki potensi besar sebagai alternatif pengobatan alami yang aman dan ekonomis. Namun, pemahaman masyarakat tentang jenis dan manfaat tanaman herbal masih tergolong rendah. Oleh karena itu, kegiatan edukasi pengenalan jenis tanaman herbal kepada masyarakat di Desa Kekeri, Lombok Barat, dilakukan untuk meningkatkan kesadaran dan pemahaman masyarakat mengenai manfaat, identifikasi, dan pengolahan tanaman herbal. Metode yang digunakan dalam kegiatan ini meliputi penyuluhan, demonstrasi praktik, dan diskusi interaktif. Evaluasi efektivitas kegiatan dilakukan melalui kuesioner yang diberikan kepada 20 peserta, dengan aspek yang dinilai meliputi pemahaman materi, keterampilan membedakan jenis tanaman herbal, kesiapan dalam mengolah tanaman herbal, relevansi materi, metode penyampaian, ketersediaan fasilitas, dan tingkat kepuasan peserta. Hasil evaluasi menunjukkan bahwa kegiatan ini sangat efektif, dengan rata-rata persentase skor sebesar 88,57%. Rincian hasil evaluasi meliputi pemahaman manfaat tanaman herbal (88%), kemampuan membedakan jenis tanaman herbal (84%), kesiapan dalam mengolah tanaman herbal (80%), relevansi materi (94%), metode penyampaian (90%), ketersediaan fasilitas (86%), dan tingkat kepuasan peserta (92%). Berdasarkan hasil ini, dapat disimpulkan bahwa edukasi ini berhasil meningkatkan pemahaman dan keterampilan masyarakat terkait tanaman herbal. Rekomendasi untuk kegiatan selanjutnya adalah menambah sesi praktik dan penyediaan bibit tanaman herbal agar masyarakat dapat langsung menerapkan ilmu yang diperoleh. Kata kunci: Edukasi, Tanaman Herbal, Pengenalan, Masyarakat, Evaluasi. ABSTRACTHerbal plants hold great potential as a safe and economical alternative for natural medicine. However, public understanding of the types and benefits of herbal plants remains relatively low. Therefore, an educational program on the identification and recognition of herbal plants was conducted in Kekeri Village, West Lombok, to enhance community awareness and knowledge regarding the benefits, identification, and processing of herbal plants. The methods employed in this program included lectures, practical demonstrations, and interactive discussions. The effectiveness of the program was evaluated using questionnaires distributed to 20 participants, assessing aspects such as comprehension of the material, ability to differentiate types of herbal plants, readiness to process herbal plants, relevance of the material, delivery methods, availability of facilities, and participant satisfaction. The evaluation results indicate that the program was highly effective, with an average score percentage of 88.57%. Specifically, the evaluation scores were as follows: understanding the benefits of herbal plants (88%), ability to differentiate types of herbal plants (84%), readiness to process herbal plants (80%), relevance of the material (94%), delivery methods (90%), availability of facilities (86%), and participant satisfaction (92%). Based on these findings, it can be concluded that this educational program successfully improved community understanding and skills related to herbal plants. Future recommendations include adding more practical sessions and providing herbal plant seedlings to enable participants to apply the knowledge gained directly. Keywords: Education, Herbal Plants, Recognition, Community, Evaluation.
Uji Analgesik Ekstrak Akar Tunjuk Langit (Helminthostachys zeylanica L.) Pada Mencit Putih Jantan (Mus musculus) Fitriana, Yuli; Hendriyani, Irmatika; Wahid, Abdul Rahman; Rasmiwati, Rasmiwati; Iradhatullah, Sri Putriani; Faisal, Muhammad; Nurbaety, Baiq; Sugara, Taufan Hari
Medika: Jurnal Ilmiah Kesehatan Vol 5 No 1 (2025): Medika: Jurnal Ilmiah Kesehatan
Publisher : Universitas Nahdlatul Ulama Nusa Tenggara Barat

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.69503/medika.v5i1.991

Abstract

Akar tunjuk langit (Helminthostachys zeylanica L.) merupakan salah satu tanaman yang dapat digunakan sebagai obat tradisional dimana di dalamnya terkandung senyawa-senyawa flavonoid, fenolik dan saponin yang mempunyai aktifitas biologis, diantaranya adalah efek analgetik dengan menghambat sintesis enzim siklooksigenase 2 (COX-2). Penelitian ini betujuan untuk mengetahui efek analgesik dari ekstrak Akar Tunjuk Langit (Helminthostachys zeylanica L.) pada Mencit putih jantan (Mus musculus). Penelitian ini menggunakan metode eksperimental Laboratorium dengan menggunakan 28 ekor Mencit putih jantan yang terbagi menjadi 6 kelompok yaitu kelompok kontrol positif (Asam Mefenamat), kontrol negatif (CMC- Na 0,5%), kontrol base line (minum add libitum) dan kelompok perlakuan ekstrak akar tunjuk langit dengan variasi dosis yaitu 100, 200 dan 300 mg/kgBB secara peroral, setelah 30 menit diberikan rangsangan kimia asam asetat 0,5 ml secara intraperitoneal. Pengujian dilakukan selama 3 hari. Parameter yang diamati adalah geliat mencit tiap 5 menit selama 60 menit. Data yang diperoleh dianalisis secara statistik dengan One- S Kolmogorov-Smirnov test, One Way Anova dan Post Hoc test (LSD) dengan taraf kepercayaan 95%. Hasil skrining fitokimia ekstrak akar tunjuk langit didapat bahwa pada pengujian metabolit sekunder flavonoid, saponin dan fenol menunjukkan hasil positif. Hasil penelitian menunjukkan bahwa persen daya analgetik dosis 100 mg/kgBB (25,77% ± 2,56), dosis 200 mg/kgBB (24,04% ± 0,78), dosis 300 mg/kgBB (29,18% ± 5,71) dan dosis Asam Mefenamat (58,48% ± 3,54). Dari hasil penelitian dapat disimpulkan bahwa ekstrak akar tunjuk langit dosis 300 mg/KgBB merupakan dosis terbaik sebagai analgetik dalam menurunkan nyeri pada mencit yang diinduksi asam asetat dengan nilai 29,18% ± 5,71 proteksi tetapi berbeda signifikan dengan dosis Asam Mefenamat.
UJI AKTIVITAS ANTIBAKTERI EKSTRAK ETANOL DAUN MIMBA (Azadirachta Indica A. Juss) TERHADAP BAKTERI Stapylococus aureus Dan Escherichia coli ST.NURJANAH, MUHAMMAD FAISAL; Hendriyani , Irmatika; Azemi , Nuruluni; Suryani, Ade Irma
JOURNAL OF PHARMACEUTICAL (JOP) Vol. 3 No. 1 (2025): Journal of Pharmaceutical (JOP)
Publisher : Lembaga Penelitian dan Pengabdian kepada Masyarakat (LPPM) UNIVERSITAS JENDERAL ACHMAD YANI YOGYAKARTA

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30989/jop.v3i1.1591

Abstract

Background: Infectious diseases remain a health problem in developing countries, including Indonesia. Antibacterials are needed to inhibit or kill bacteria that cause infections. Neem leaves (Azadirachta indica A. Juss) are traditionally known to contain active compounds such as flavonoids, alkaloids, and tannins that have antibacterial potential. Several studies have shown that ethanol extracts of neem leaves are effective against bacteria such as Staphylococcus aureus and Escherichia coli. Objective:  The purpose of this study was to conduct phytochemical screening to determine the secondary metabolite content in mimba leaf extract and to test the antibacterial activity of 5%; 10%; 20%; 40%, and 80% ethanol extracts of mimba leaves against Staphylococcus aureus and Escherichia coli bacteria. Method:  Mimba leaves were extracted using the maceration method with 96% ethanol solvent. Antibacterial activity was tested using the well diffusion method with treatments of 5%; 10%; 20%; 40%, and 80% groups and a negative control group using DMSO. Results:  The inhibition zone diameters of Staphylococcus aureus and Escherichia coli at a concentration of 5% were 1,2 mm and 2 mm respectively, while the inhibition zone diameters at a concentration of 80% were 17,4 mm and 16 mm respectively. Cunclusion:  Concentrations of mimba leaf extract of 5%; 10%; 20%; 40%; and 80% showed antibacterial activity against Staphylococcus aureus and Escherichia coli. The higher the concentration, the larger the diameter of the inhibition zone formed
Antibacterial Activity Test of Ethanol Extract of Palm Leaves (Catharantus roseus) Against Staphylococcus aureus and Escherichia coli Bacteria Fitriana, Yuli; Iradhatullah, Sri Putriani; Sugara, Taufan Hari; Hendriyani, Irmatika; Nurbaety, Baiq; Faisal, Muhammad
THRIVE Health Science Journal Vol. 2 No. 2 (2025): September
Publisher : Balai Publikasi Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.56566/thrive.v2i2.424

Abstract

Ethanol extract of virgin palm leaves (Catharantus roseus) contains active compounds that have potential as natural antibacterial. This study aims to test the antibacterial activity of the extract against Staphylococcus aureus and Escherichia coli bacteria. The leaves of the tread are extracted using the maceration method with a 70% ethanol solvent. The extraction results showed a yield of 6.1% and the identification of compound content showed the presence of alkaloids, flavonoids, saponins, tannins, and phenols. The antibacterial test was carried out by disc diffusion method using concentrations of 60%, 80%, and 100%. Antibacterial activity was tested by calculating the resulting inhibition zones against both types of bacteria. The results showed that in Staphylococcus aureus bacteria, the concentration of 100% resulted in an inhibition zone of 11.66 mm which was classified as strong. In contrast, in Escherichia coli bacteria, the same concentration resulted in an inhibition zone of 2.66 mm which was in the weak category. This difference in effectiveness is due to the cell wall structure of gram-positive and gram-negative bacteria. The results of this study identified that ethanol extract of virgin leaves has a greater potential for gram-positive bacteria than gram-negative. The ethanol extract of virgin leaves demonstrated antibacterial activity against both Staphylococcus aureus and Escherichia coli, with stronger effects observed against S. aureus.
Sex education: meminimalisir penyakit menular seksual melalui peran aktif majelis kesehatan Dzun Haryadi Ittiqo; Anna Pradiningsih; Nurul Qiyaam; Baiq Leny Nopitasari; Muhammad Faisal; Ni Wayan Ari Adiputri; Gusti Ayu Puti Sri Erwinayanti; Intan Sri Hartanti; I Ketut Wisnu Arya Wiratama; Umul Mutmainah
SELAPARANG: Jurnal Pengabdian Masyarakat Berkemajuan Vol 9, No 4 (2025): Juli
Publisher : Universitas Muhammadiyah Mataram

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31764/jpmb.v9i4.33261

Abstract

AbstrakPendidikan seksual adalah keterampilan dan pengetahuan yang penting untuk diajarkan sejak dini kepada anak-anak, mengenai perilaku seksual, guna mempersiapkan mereka menghadapi perubahan seiring bertambahnya usia serta membentuk karakter dan pola perilaku agar mereka dapat menghindari risiko pelecehan seksual dan perilaku seksual menyimpang. Kegiatan pengabdian ini dilakukan pada di Aula Posyandu Lingkungan Pagesangan Indah, Kota Mataram. Pemilihan kelompok sasaran ditentukan dengan banyaknya remaja sekitar kampus. Kemudain tim menganalisa jumlah masyarakat pada lingkungan mitra sebagai target sasaran pengabdian masyarakat. Target sasaran kegiatan ini adalah Kepala Lingkungan, Kader Lingkungan, Dai kesehatan, Kepala RT dan Perwakilan Kampung Keluarga Berencana (KKB). Kegiatan deteksi dan edukasi terkait dengan sex education dalam meminimalisir IMS sangat bermanfaat untuk memberikan pemahaman kepada mitra terkait fenomena yang terjadi di masyarakat. Edukasi ini dimaksudkan untuk menekan angka paparan IMS. Kata kunci: sex education; infeksi menular seksual; mejelis kesehatan muhammadiyah AbstractSex education is an essential skill and knowledge that should be taught to children from an early age, focusing on sexual behavior, in order to prepare them for changes as they grow older and to help shape their character and behavior patterns so they can avoid the risks of sexual abuse and deviant sexual behavior. This community service activity was carried out at the Posyandu Hall in the Pagesangan Indah neighborhood, Mataram City. The target group was chosen based on the large number of adolescents living near the campus. The team then analyzed the population in the partner community area to determine the target of the community service. The target audience of this activity included the Neighborhood Head, Community Health Cadres, Health Preachers (Dai Kesehatan), Neighborhood Chiefs (RT Heads), and representatives from the Family Planning Village (KKB). The detection and education activities related to sex education aimed at minimizing sexually transmitted infections (STIs) were very beneficial in providing partners with understanding about phenomena occurring in society. This education is intended to reduce the incidence of STI exposure. Keywords: sex education; sexually transmitted infections (STI); muhammadiyah health council
Co-Authors Ade Irma Suryani Anna Pradiningsih Azemi , Nuruluni Baiq Leny Nopitasari Baiq Lenysia Puspita Anjani, Baiq Lenysia Puspita Baiq Nurbaety Dewi, Melynia Sintha Dzun Haryadi Ittiqo Gani, Michael Raharja Gusti Ayu Puti Sri Erwinayanti Hendriyani , Irmatika Hendriyani, Irmatika I Ketut Wisnu Arya Wiratama Intan Sri Hartanti Iradhatullah, Sri Putriani Irmatika Hendriyani Lutfi Chabib, Lutfi Ni Wayan Ari Adiputri Nopitasari, Baiq Leny NURSELA HIJRIANI Nurul Qiyaam, Nurul Pradiningsih, Anna Puspitasari, Sintha Rahmawati, Cyntiya Rasmiwati, Rasmiwati Rini Dwiastuti Safwan Safwan, Safwan Taufan Hari Sugara Umul Mutmainah Wahid, Abdul Rahman Widayatul Khairi Yuli Fitriana