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Contact Name
mahardika
Contact Email
p3i@umsida.ac.id
Phone
6282143483630
Journal Mail Official
perpus@umsida.ac.id
Editorial Address
jl. Mojopahit No. 666B Sidoarjo, Jawa Timur
Location
Kab. sidoarjo,
Jawa timur
INDONESIA
Indonesian Journal Health Science and Medicine
ISSN : -     EISSN : 30638186     DOI : https://doi.org/10.21070/ijhsm
Core Subject : Health,
Focus: The Indonesian Journal on Health Science and Medicine (IJHSM) focus to advance the field of health science and medicine by publishing high-quality, peer-reviewed research articles, reviews, and case studies. Our journal serves as a platform for researchers, clinicians, and healthcare professionals to share innovative findings, critical insights, and emerging trends in the broad domain of health science and medicine. Scope: Clinical Research and Practice Studies on the diagnosis, treatment, and prevention of diseases. Clinical trials and evidence-based practices. Advances in medical technology and therapeutics. Public Health Epidemiology and health statistics. Health policy and management. Community health initiatives and health education. Biomedical Science Research on cellular and molecular biology. Genetics and genomics. Pharmacology and toxicology. Health Care Systems and Services Health care delivery and management. Quality improvement in health care services. Health economics and health informatics. Global Health Health issues affecting populations worldwide. International health regulations and practices. Global health governance and diplomacy. Health Promotion and Disease Prevention Lifestyle and behavioral interventions. Preventive medicine and early detection. Nutritional science and physical activity. Mental Health Research on mental health disorders and treatments. Psychological well-being and mental health promotion. Integration of mental health services in primary care. Innovations in Health Education and Training Medical and health science education methodologies. Training programs for health professionals. Continuing education and professional development.
Articles 332 Documents
Prevalence and Antibiotic Susceptibility of Gram-Positive, Gram-Negative Bacteria and Candida in UTI Clinical Samples Ameer A. Karim; Alaa H. Abd Ali; Enas K. Alkhazraji; Sajjad S. Hameed
Indonesian Journal on Health Science and Medicine Vol. 3 No. 1 (2026): July
Publisher : Universitas Muhammadiyah Sidoarjo

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21070/ijhsm.v3i1.465

Abstract

General Background: Urinary tract infections (UTIs) are among the most common infections affecting the urinary system, including the urethra, kidneys, and bladder. Specific Background: In Iraq, the spectrum of UTI pathogens and their antibiotic resistance patterns remain insufficiently characterized, particularly in Al-Najaf province. Knowledge Gap: Limited data exist on the distribution of gram-positive, gram-negative, and fungal uropathogens alongside their antibiotic susceptibility profiles in both male and female outpatients in this region. Aims: This study aimed to identify the pathogen spectrum of UTIs, determine the distribution in women and men, and evaluate antibiotic resistance levels of isolated strains. Results: Among 618 outpatients, the most clinically significant microorganisms were Staphylococcus aureus (27.3%), Escherichia coli (25.4%), Staphylococcus epidermidis (17.0%), Streptococcus spp. (16.3%), and Candida albicans (6.1%). Women accounted for 89.8% of infections; C. albicans was detected only in women (6.1%). Highest resistance was observed to cefotaxime (up to 100% in Pseudomonas aeruginosa). Vancomycin (2% resistance) and amikacin (6-39% resistance) were the most effective antibiotics, with amikacin particularly effective against gram-negative bacteria. Novelty: This study provides the first comprehensive UTI pathogen and resistance profile from Al-Sajjad Hospital, Najaf, revealing S. aureus as the predominant pathogen over E. coli, contrasting with global trends. Implications: Empirical UTI therapy in this region should consider vancomycin and amikacin as potential options while avoiding cefotaxime, and clinicians should recognize the high female predominance and unique pathogen hierarchy. Highlights : Staphylococcus aureus (27.3%) outnumbered Escherichia coli (25.4%) as the leading UTI pathogen in Al-Najaf, Iraq. Candida albicans (6.1%) was detected exclusively in female patients with UTIs. Cefotaxime resistance reached 100% in Pseudomonas aeruginosa, while vancomycin showed only 2% resistance across gram-positive cocci. Keywords: Urinary Tract Infections, Antibiotic Resistance, Staphylococcus Aureus, Escherichia Coli, Iraq
Investigating the Impact of Sex Hormones on Obesity-Related Secondary Infertility in Women Saba Sabeeh Hussein
Indonesian Journal on Health Science and Medicine Vol. 3 No. 1 (2026): July
Publisher : Universitas Muhammadiyah Sidoarjo

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21070/ijhsm.v3i1.472

Abstract

General Background: Secondary infertility remains a significant reproductive health concern worldwide, and obesity has emerged as an important factor associated with endocrine and metabolic disturbances that may compromise female fertility. Specific Background: Obesity has been linked to alterations in gonadotropin secretion, thyroid function, prolactin levels, and lipid metabolism; however, evidence regarding these associations among women with secondary infertility remains limited. Knowledge Gap: Data evaluating hormonal and metabolic differences between obese and non-obese women with secondary infertility, particularly in Iraqi populations, are scarce. Aims: This study aimed to compare reproductive hormones, thyroid function, prolactin levels, and lipid profiles between obese and non-obese women diagnosed with secondary infertility. Results: Obese women demonstrated significantly lower luteinizing hormone and thyroid-stimulating hormone levels, together with significantly higher total cholesterol and triglyceride concentrations than non-obese women. Prolactin levels were elevated in both groups without significant between-group differences. Age-adjusted analyses confirmed the persistence of the luteinizing hormone and lipid profile differences. Body mass index correlated with triglycerides in obese women and with cholesterol in non-obese women. Novelty: The study provides evidence from a carefully selected secondary infertility cohort while excluding major confounding reproductive and endocrine conditions. Implications: The findings support the incorporation of early body mass index assessment, metabolic screening, and weight-management strategies into the evaluation and management of secondary infertility. Keywords: Secondary Infertility, Obesity, Luteinizing Hormone, Lipid Profile, Reproductive Endocrinology Key Findings Highlights Reduced gonadotrophin concentrations were identified among participants with elevated body mass index. Metabolic abnormalities were characterized by increased cholesterol and triglyceride concentrations. Age-adjusted analyses confirmed the robustness of the endocrine and biochemical differences.
Impact Analysis of Intervention of Community Pharmacists in Enhancing Patient Medication Niyazi Burhan Aldin Mohammad; Marwan M. Merkhan
Indonesian Journal on Health Science and Medicine Vol. 3 No. 1 (2026): July
Publisher : Universitas Muhammadiyah Sidoarjo

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21070/ijhsm.v3i1.475

Abstract

General Background Medication adherence represents a fundamental determinant of therapeutic success, whereas non-adherence triggers treatment failure and escalates global healthcare expenditures. Specific Background Community pharmacists are uniquely positioned as accessible frontline healthcare providers capable of delivering patient-centered pharmaceutical care and clinical counseling beyond traditional drug dispensing. Knowledge Gap However, the documented effectiveness of these pharmacy-led programs remains variable across different clinical settings, and synthesized data regarding their systemic impact on diverse disease states remain limited. Aims This study evaluates the impact of community pharmacist-led interventions on patient medication compliance and comprehensive health outcomes across multiple chronic conditions. Results The findings demonstrate that structured community pharmacy services significantly enhance drug compliance and optimize disease control, yielding marked improvements in blood pressure regulation, asthma control, chronic obstructive pulmonary disease management, and cholesterol level optimization. Conversely, educational interventions delivered exclusively by pharmacists demonstrate no significant impact on mitigating depressive symptoms in adult outpatients. Novelty This comprehensive review systematically maps multi-disciplinary pharmacy interventions across respiratory, cardiovascular, metabolic, and postoperative care settings to delineate the explicit clinical boundaries of independent pharmaceutical counseling. Implications These results indicate that integrating community pharmacists into primary care pathways optimizes long-term therapeutic outcomes and reduces hospitalizations for chronic diseases, though mental health care requires a more integrated, multidisciplinary approach. Keywords: Medication Adherence, Community Pharmacist, Chronic Disease, Patient Compliance, Health Outcomes Key Findings Highlights Community pharmacy programs significantly improve objective clinical markers for blood pressure, asthma, and cholesterol management. Independent pharmacist-led educational interventions fail to produce measurable reductions in adult depressive symptomology. Integrated pharmaceutical care reduces hospital stays and decreases medication errors during transitions in postoperative and cystic fibrosis care.
Biochemical Indicators of Endometrial Receptivity in Uterine Function Manal Abdulmunem Ibrahim
Indonesian Journal on Health Science and Medicine Vol. 3 No. 1 (2026): July
Publisher : Universitas Muhammadiyah Sidoarjo

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21070/ijhsm.v3i1.477

Abstract

Background: Endometrial receptivity is a critical prerequisite for successful embryo implantation and pregnancy, involving complex molecular interactions within the uterus. Specific Background: Implantation failure remains a major cause of infertility and recurrent implantation failure, despite advances in assisted reproductive technologies. Numerous biomolecules, including genes, proteins, microRNAs, extracellular vesicles, hormones, immune mediators, and microbial-related factors, have been investigated as indicators of uterine receptivity. Knowledge Gap: Although many biomarkers have been reported, comprehensive synthesis of recent evidence regarding biochemical indicators associated with receptive and non-receptive endometrium remains limited. Aims: This review aimed to summarize contemporary evidence regarding biomolecules associated with endometrial receptivity and implantation success. Results: Analysis of studies published between 2019 and 2023 identified multiple biomarkers linked to receptive endometrium, including HOXA10, LIF, CTNNA2, annexins, integrins, mucins, osteopontin, CD44, IGFBP-7, CK7, extracellular vesicle-associated microRNAs, CD63, and progesterone-related pathways. In contrast, implantation failure was associated with reduced HSD17B2, AZGP1, TPPP3, S100A13, estrogen receptor β, progesterone receptors, and progesterone levels, alongside dysregulated immune profiles, altered microRNA expression, elevated CD9, oxidative stress, microbial disturbances, mitochondrial dysfunction, and cellular senescence. Novelty: This review integrates recent findings on genetic, proteomic, transcriptomic, immunological, hormonal, and extracellular vesicle-derived biomarkers relevant to endometrial receptivity. Implications: Identification and characterization of these biomarkers may support minimally invasive assessment of uterine receptivity, improve implantation prediction, and facilitate personalized management strategies for infertility and recurrent implantation failure. Keywords: Endometrial Receptivity, Embryo Implantation, Recurrent Implantation Failure, Extracellular Vesicles, Biomarkers Key Findings Highlights Multiple genes, proteins, and extracellular vesicle contents were associated with successful implantation. Recurrent implantation failure was characterized by molecular, immune, hormonal, and metabolic dysregulation. Minimally invasive uterine fluid analysis provides promising approaches for receptivity assessment.
Public Knowledge of Diabetes Mellitus: A Cross-Sectional Study Suaad Abduljabar Abdulwahd Almudhafar
Indonesian Journal on Health Science and Medicine Vol. 3 No. 1 (2026): July
Publisher : Universitas Muhammadiyah Sidoarjo

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21070/ijhsm.v3i1.478

Abstract

General Background: Diabetes mellitus is a major non-communicable disease with a rapidly increasing global prevalence, making public awareness and understanding essential for disease prevention and management. Specific Background: Assessing public knowledge of diabetes mellitus can provide valuable information for identifying strengths and deficiencies in community awareness regarding the disease. Knowledge Gap: Although diabetes knowledge has been investigated in several populations, limited evidence was available regarding the level of public knowledge in Basrah City, Iraq, particularly concerning specific aspects of diabetes such as complications and management. Aims: This study aimed to assess public knowledge of diabetes mellitus among adults attending primary health care centers in Basrah City. Methods: A descriptive cross-sectional study was conducted between January and May 2009 among 600 diabetic and non-diabetic adults attending four primary health care centers. Knowledge was assessed using a structured questionnaire covering diabetes definition, risk factors, complications, prevention, control, and management. Results: More than half of the participants (55.5%) demonstrated a good level of diabetes knowledge, 35.2% showed an acceptable level, and 9.3% had poor knowledge. Higher proportions of correct responses were observed for diabetes control (71%) and risk factors (69%), whereas lower proportions were found for complications (56.7%) and management (53%). Novelty: This study provides population-based evidence on public diabetes knowledge in Basrah City and identifies specific knowledge deficiencies related to diabetes complications and management. Implications: The findings indicate generally satisfactory public awareness while highlighting the need for targeted educational interventions focusing on diabetes complications and disease management to strengthen community understanding and support diabetes control efforts. Keywords: Diabetes Mellitus, Public Knowledge, Health Awareness, Primary Health Care, Cross-Sectional Study   Key Findings Highlights More than half of participants demonstrated a high level of understanding regarding the disease. Correct responses were highest for disease control and associated risk factors. Deficiencies were identified in awareness related to complications and treatment management.
Fosfomycin in the Clinical Practice of Urinary Tract Infection Islam Tariq
Indonesian Journal on Health Science and Medicine Vol. 3 No. 1 (2026): July
Publisher : Universitas Muhammadiyah Sidoarjo

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21070/ijhsm.v3i1.479

Abstract

General Background: Urinary tract infections (UTIs) are among the most common bacterial infections worldwide, affecting millions of individuals and occurring more frequently in women due to anatomical factors. Specific Background: The increasing prevalence of antimicrobial resistance among uropathogens, particularly Escherichia coli, has complicated conventional treatment approaches and renewed interest in alternative therapeutic agents. Knowledge Gap: Although fosfomycin has gained attention as a treatment option for UTIs, a comprehensive overview of its clinical applications, safety profile, and use in special populations remains important. Aims: This study reviews the role of fosfomycin in the clinical management of UTIs, including its mechanism of action, therapeutic applications, adverse effects, contraindications, and use in pregnant women and pediatric patients. Results: Fosfomycin exhibits broad-spectrum bactericidal activity against Gram-positive and Gram-negative bacteria, including multidrug-resistant pathogens, through inhibition of bacterial cell wall synthesis. Clinical evidence indicates that both single-dose and multiple-dose regimens are utilized according to infection severity and patient characteristics. The drug is generally well tolerated, although gastrointestinal disturbances, electrolyte abnormalities, hypersensitivity reactions, and specific contraindications have been reported. Fosfomycin is frequently recommended for UTIs during pregnancy and has demonstrated utility in pediatric patients, particularly in infections caused by resistant organisms. Novelty: This review consolidates current evidence regarding fosfomycin use across diverse UTI settings, including resistant infections and special patient populations. Implications: Fosfomycin represents a valuable therapeutic option for UTI management in the context of growing antimicrobial resistance and increasing demand for alternative antibacterial therapies. Highlights:• Fosfomycin demonstrates activity against Gram-positive, Gram-negative, and multidrug-resistant uropathogens.• Treatment regimens vary from single-dose administration to repeated dosing based on infection complexity.• Clinical applications include management of UTIs in pregnant women and pediatric populations. Keywords: Fosfomycin, Urinary Tract Infection, Antimicrobial Resistance, Pregnancy, Pediatric Patients
Factors Influencing the Public’s Knowledge about Diabetes Mellitus Suaad Abduljabar Abdulwahd Almudhafar
Indonesian Journal on Health Science and Medicine Vol. 3 No. 1 (2026): July
Publisher : Universitas Muhammadiyah Sidoarjo

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21070/ijhsm.v3i1.480

Abstract

General Background: Diabetes mellitus is a major global public health concern that contributes substantially to morbidity and mortality and requires adequate public awareness for effective prevention and management. Specific Background: Understanding the factors associated with diabetes knowledge is essential for improving health education and reducing the burden of the disease. Knowledge Gap: Limited evidence is available regarding demographic characteristics associated with diabetes knowledge among the public in Basrah, Iraq. Aims: This study aimed to identify the factors associated with the public’s knowledge about diabetes mellitus. Methods: A descriptive cross-sectional study was conducted in Basrah using a structured questionnaire administered to 600 participants. Data were analyzed using SPSS version 26. Results: The findings showed significant associations between diabetes knowledge and age, sex, and educational level. Poor knowledge decreased with increasing age, while the highest proportion of good knowledge was observed among individuals aged 30–50 years. Males demonstrated slightly higher levels of good knowledge than females. Knowledge levels increased substantially with educational attainment, with the highest proportion of good knowledge observed among participants with university education and above. Novelty: The study provides recent evidence from Basrah regarding demographic characteristics associated with public diabetes knowledge. Implications: The findings suggest that health education initiatives should consider demographic differences when designing diabetes awareness and prevention programs. Keywords: Diabetes Mellitus, Public Knowledge, Health Education, Demographic Factors, Basrah   Key Findings Highlights Knowledge levels improved across older age categories. Male participants demonstrated slightly better awareness than female participants. Higher educational attainment corresponded to greater understanding of the disease.
Assessment of Mothers’ Knowledge about Breastfeeding in Basra City Hadeel H. Haider; Noor Hasan Mohamed Taqi; Nuha Muhsen Mhebis
Indonesian Journal on Health Science and Medicine Vol. 3 No. 1 (2026): July
Publisher : Universitas Muhammadiyah Sidoarjo

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21070/ijhsm.v3i1.485

Abstract

General Background Breastfeeding is essential for child development and protects against infant mortality. Specific Background Human milk is the recommended exclusive nutrient source during the first six months of life, making maternal understanding of proper lactation techniques crucial for successful child health outcomes. Knowledge Gap Although formal education generally correlates with better health literacy, it remains unclear why mothers with high educational attainment still display significant awareness gaps regarding optimal breastfeeding practices. Aims This study assessed mothers' knowledge about breastfeeding and evaluated their primary information sources within primary healthcare settings in Basra City. Results Out of 158 participants, 76.6 percent resided in urban areas and 46.2 percent completed college. Crucially, 79.7 percent of mothers exhibited poor breastfeeding knowledge, and 62 percent received only simple reassurance from health centers. Medical facilities were the most frequent knowledge source for 28 percent of respondents, followed closely by the internet at 27 percent, while family and friends accounted for 11 percent. Novelty This study reveals a critical paradox where high formal college education fails to translate into adequate breastfeeding literacy among urban housewives in Basra. Implications Primary healthcare centers must shift from basic reassurance to well-designed, structured prenatal and postnatal lactation counseling programs to rectify widespread institutional knowledge gaps. Keywords: Breastfeeding, Maternal Knowledge, Lactation Counseling, Public Health, Primary HealthcareKey Findings HighlightsWidespread knowledge deficiencies exist among mothers, with 79.7 percent demonstrating poor breastfeeding literacy.High formal college education does not guarantee adequate awareness regarding optimal infant feeding practices.Primary healthcare centers provide minimal counseling support, leaving the internet as a nearly equal source of maternal information.
Urban Residence and Genetic Predisposition Underlying Breast Cancer Distribution in Iraq Raheem Abd Zaid Al Abedi
Indonesian Journal on Health Science and Medicine Vol. 3 No. 1 (2026): July
Publisher : Universitas Muhammadiyah Sidoarjo

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21070/ijhsm.v3i1.486

Abstract

General Background Breast cancer represents a major global health challenge and is the leading cause of oncological mortality among women. Specific Background In the Eastern Mediterranean region and specifically within Al-Najaf province, Iraq, registered cancer cases have risen significantly from 2020 to 2025, with breast malignancies consistently topping annual health registries across regional oncology facilities. Knowledge Gap Although structural risk factors are generally recognized, multi-center epidemiological data evaluating the overlapping influence of environmental, genetic, demographic, and lifestyle variables within this specific geographic population remain highly limited. Aims This investigation aimed to describe the temporal distribution of breast cancer cases in Al-Najaf province from 2020 to 2025 and identify associations with potential demographic, genetic, and environmental risk factors among 800 consecutively enrolled female patients across four public and private oncology centers. Results Statistical analysis demonstrated that urban residents accounted for 73.3% of cases, revealing a highly significant predominance compared to rural districts ($p \le 0.05$). A positive family history of breast or ovarian cancer was reported by 46.7% of patients, the peak age group was 40–60 years representing 56.7% of the cohort, and married women constituted 76.7% of cases. Locally advanced disease at stages II and III comprised 66.7% of diagnoses, with chemotherapy serving as the primary treatment modality. Novelty This study provides the first large-scale, multi-center evidence integrating private sector oncology data to demonstrate the critical role of urban living environments and hereditary patterns in southern Iraq. Implications These findings establish an urgent need for population-based screening programs, urban environmental mitigation strategies, and accessible genetic counseling infrastructure. Keywords: Breast Neoplasms, Risk Factors, Environmental Pollution, Genetics, Iraq   Key Findings Highlights Urban residency demonstrates a statistically significant association with higher breast cancer frequency compared to rural environments. Hereditary predisposition is highly prevalent, with nearly half of the diagnosed cohort presenting a positive maternal family history. Locally advanced stages dominate clinical presentation, necessitating chemotherapy as the primary therapeutic management approach.
Postpartum Anxiety Levels and Neonatal Care Responses Among Primiparous Mothers: Postpartum Anxiety Levels and Neonatal Care Responses Among First-Time Mothers Nurul Azizah; Mela Nailul Izza
Indonesian Journal on Health Science and Medicine Vol. 3 No. 1 (2026): July
Publisher : Universitas Muhammadiyah Sidoarjo

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21070/ijhsm.v3i1.487

Abstract

General Background The puerperal phase triggers significant physiological, psychological, and social transitions that require structured clinical monitoring to prevent severe maternal affective disorders. Specific Background Primiparous women exhibit heightened vulnerability to postpartum anxiety and depression compared to multiparous mothers due to childbirth unfamiliarity. Knowledge Gap However, maternal psychological adaptive patterns remain under-examined when complicated by unexpected infant clinical vulnerabilities that mandate specialized neonatal care. Aims This case study evaluates maternal postpartum anxiety triggered by newborn health complications in a 26-year-old primigravida. Results Psychometric screening using the Depression Anxiety Stress Scales confirmed mild anxiety (score: 8) caused by excessive cognitive overthinking, structural adaptation difficulties, and initial caregiving unfamiliarity. Novelty The evaluation demonstrates that immediate modification of external stressors, such as reducing social media consumption alongside active family support, effectively minimizes postpartum stress. Implications Midwives must provide comprehensive, continuous, and long-term psychosocial interventions to secure optimal maternal-infant health outcomes. Keywords: Postpartum Anxiety, Primigravida, Neonatal Care, Maternal Psychology, Clinical Midwifery Key Findings Highlights Psychometric assessment via the Depression Anxiety Stress Scales identifies a mild anxiety baseline score of 8 in primiparous tracking. Sudden requirements for specialized newborn medical care serve as an immediate trigger for acute maternal cognitive overthinking. Combining targeted social media reduction with consistent familial assistance actively minimizes postpartum emotional distress.