cover
Contact Name
Prasetyadi Mawardi
Contact Email
prasetyadimawardi@yahoo.com
Phone
+6287834999959
Journal Mail Official
jurnalibehs@gmail.com
Editorial Address
Bagian Pendidikan & Penelitian RSUD Dr. Moewardi Jl. Kol. Soetarto 132 Fax (0271) 666954 Surakarta
Location
Kota surakarta,
Jawa tengah
INDONESIA
Indonesian Basic and Experimental Health Sciences
Published by RSUD Dr. Moewardi
ISSN : -     EISSN : 30255929     DOI : 10.11594/ibehs
Core Subject : Health,
Indonesian Basic and Experimental Health Sciences Journal (IBEHS) is a health journal published by RSUD Dr. Moewardi Surakarta, Central Java, Indonesia as a contribution to RSUD Dr. Moewardi for the development and progress of health science which is marked by various innovations and creativity of health workers, both in the Dr. Moewardi or other health workers who are always concerned about education, research, and community service in the health sector.
Articles 30 Documents
The Differences In The Quality Of Mixed Material Radiation Aprons At Dr. Moewardi Hospital With A Review Of Attenuation Coefficient Analysis Alviana Hapsari Purbarani; Umaimah, Umi; Eka Prasetya, Firman
Indonesian Basic and Experimental Health Sciences Vol. 14 No. 1 (2025): November
Publisher : Rumah Sakit Umum Daerah Dr. Moewardi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.11594/ibehs.vol14iss1pp73-79

Abstract

IntroductionRadiation aprons are essential protective equipment in radiology, and the Regulation of the Head of BAPETEN No. 4 of 2020 requires aprons in Diagnostic and Interventional Radiology units to provide protection equivalent to 0.25 mmPb, 0.35 mmPb, or 0.5 mmPb. This study aimed to evaluate the quality of mixed-material radiation aprons at Dr. Moewardi Hospital by analyzing their attenuation coefficients. MethodsThis study assessed several apron brands available in the Radiology Installation and Cathlab Unit. Measurements were performed using a GE Proteus X-ray machine and a Raysafe X-ray Multimeter Detector. The X-ray parameters were set at 100 kV, 10 mAs, 100 cm tube-to-detector distance, and a 5 × 5 cm irradiation field, with variations in apron thickness. The reference attenuation coefficient of Pb under the same parameters was calculated as 6.32 mm⁻¹. Apron brands tested included Primax 0.35 mmPb, ProteX 0.5 mmPb, Infab 0.25 mmPb, Lead X 0.25 mmPb, Rayshield 0.25 mmPb, Xenolite 0.35 mmPb, and Trucomfii 0.5 mmPb. Results The attenuation coefficients obtained were 4.67 mm⁻¹, 4.49 mm⁻¹, 4.476 mm⁻¹, 3.94 mm⁻¹, 3.04 mm⁻¹, 2.63 mm⁻¹, and 2.22 mm⁻¹, respectively. The highest coefficient was observed in the Lead X 0.25 mmPb apron. All apron attenuation coefficients were lower than the Pb reference value. ConclusionAll mixed-material aprons evaluated demonstrated lower attenuation coefficients compared with pure Pb under identical exposure conditions. These findings indicate variability in protective performance across brands, highlighting the need for routine quality assessment to ensure compliance with regulatory requirements.
The Differences In The Occurrence Of Drug-Related Problems And The Duration Of The Assessment Of Pediatric Chemotherapy Prescriptions Before And After The Implementation Of The Electronic-Based Cytotoxic Drug Reconstitution Guidance System At Dr. Moewardi Hospital: Pharmaceutical Installation of Dr. Moewardi Hospital Pridiyanto; Agus Suryadi, Bambang; Shaffira, Mutthia; Zaroh, Fatimah
Indonesian Basic and Experimental Health Sciences Vol. 14 No. 1 (2025): November
Publisher : Rumah Sakit Umum Daerah Dr. Moewardi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.11594/ibehs.vol14iss1pp65-72

Abstract

Abstract. Introduction Assessment of pediatric chemotherapy prescriptions is essential for preventing Drug-Related Problems (DRPs). A preliminary review showed that 57% of pediatric injectable chemotherapy patients were at risk of potential DRPs, contributing to prolonged assessment times. These issues indicate the need for systematic improvements to enhance medication safety and workflow efficiency. This study aimed to evaluate differences in DRP incidence and prescription assessment duration before and after implementing an electronic cytotoxic reconstitution guidance system. Method An experimental design was used to compare assessments before and after implementation of the electronic guidance system. A total of 60 pediatric chemotherapy prescriptions were analyzed, consisting of 30 assessed without the system (control) and 30 assessed after implementation (treatment). DRP occurrences were documented, and assessment duration was measured in minutes and seconds. Statistical analyses were performed to identify differences between groups, with significance set at P < 0.05. Results In the control group, 26 DRPs were identified, compared with 6 in the treatment group. Statistical analysis confirmed that the guidance system significantly reduced DRP incidence (P < 0.05). The mean assessment duration also decreased substantially from 7 minutes 2 seconds before implementation to 3 minutes 18 seconds afterward, and this reduction was statistically significant (P < 0.05). Conclussion The electronic cytotoxic reconstitution guidance system effectively enhances the safety and efficiency of pediatric chemotherapy prescription assessments. It significantly reduces DRP incidence and shortens assessment duration, demonstrating its value in improving workflow and supporting safer chemotherapy services.
Low Serum Anti Mullerian Hormone as a Risk Factor for Cardiovascular Disease in Child-Bearing Age Women Ratnani, Daniela; Pramudianti, M.I. Diah
Indonesian Basic and Experimental Health Sciences Vol. 14 No. 1 (2025): November
Publisher : Rumah Sakit Umum Daerah Dr. Moewardi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.11594/ibehs.vol14iss1pp80-88

Abstract

IntroductionCardiovascular disease (CVD) is the leading cause of global death. Incidence of having CVD is influenced by general risk factors and gender-related risk (preeclampsia, miscarriage, premature birth, contraception and hormonal therapy). Women of childbearing age have lower risk of CVD than men. Anti Mullerian Hormone (AMH) can be used to predict CVD. This study aimed to know association between Serum AMH level with CVD. MethodsThis study was an observational analytic, cross-sectional study. Subjects study is women with childbearing age (18-44 years old) who doing laboratory examination from May until November 2024. The exclusion criteria were patients who under chemoradiation therapy, pregnancy and have history of fertility disorder such as polycystic ovarian syndrome (PCOS). Data was subjected to bivariate testung chi square and multivariate regression logistic with Statistical Package for the Sociak Sciences (SPSS) version 29.0. ResultsA total of 57 subjects were being analyzed. Bivariate analysis showed that Serum AMH (p<0,001) have correlation with CVD. Multivariate analysis shows that Serum AMH <0,69 ng/mL (p<0,001; RR=34,049) were independently associated with CVD. ConclusionsSerum AMH <0,69 ng/mL (PR:34,05; 95% CI: 6,245–185,630, p=<0,001) increased risk of having CVD in women with childbearing age.
Can the Calculator Clinic Deter Hypoglycemia, Prevent Hypoglycemia in Hemodialysis Patients, and Reduce D40% Use? Anindhita, Rakhma; Kiswanto, Agus; Noviana, Siska Andika; Juwandi, Juwandi; Darmawan, Rendi Editya
Indonesian Basic and Experimental Health Sciences Vol. 14 No. 1 (2025): November
Publisher : Rumah Sakit Umum Daerah Dr. Moewardi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.11594/ibehs.vol14iss1pp89-97

Abstract

IntroductionHypoglycemia is a common complication in diabetic nephropathy (DN) patients undergoing hemodialysis. Early detection is essential to prevent adverse outcomes. A calculator-based clinical tool (cyclic hypoglycemia calculator) was developed to estimate hypoglycemia risk and guide additional glucose needs. This study aimed to analyze the effect of using the calculator on preventing hypoglycemia during hemodialysis. MethodsA quasi-experimental pre–post test control group design was conducted among hemodialysis patients at Dr. Moewardi Hospital (March–July 2024). Samples were selected via simple random sampling: odd medical record numbers for the control group and even numbers for the intervention group. The intervention group received hypoglycemia-risk calculation and glucose adjustment recommendations, while the control group followed standard procedures. Blood glucose levels were measured before and after 4-hour hemodialysis using a standardized glucometer. Data were homogeneous (P=0.903) and non-normally distributed (P=0.00), so the Mann–Whitney test was applied. ResultsThere was no significant difference in blood glucose levels between groups (P=0.811). Pre-dialysis glucose levels were similar (115.45 vs. 114.71 mg/dL), and post-dialysis levels remained comparable (99.39 vs. 98.21 mg/dL). In the control group, 33% experienced increased glucose, 3% remained unchanged, and 64% decreased, with an average reduction of 33.67 mg/dL. In the intervention group, 36% increased and 64% decreased, with an average reduction of 24.5 mg/dL. ConclusionsThe hypoglycemia-deterrent calculator did not produce significant differences in glucose levels compared with standard care. However, its use showed 75% efficiency in reducing unnecessary D40% administration. Further studies are recommended to refine D40% dosing strategies during hemodialysis based on individualized risk scoring.
Combined Immunosuppressive Therapy (Corticosteroid-Cyclosporine) on Hospital Stay in Patients with SevereCutaneous Adverse Reactions perspective of health worker: A Qualitative Study Widhiati, Suci; -, Hastika Dwi Oktiningrum; Tansil, Ivana; Arrosyid, Azhar
Indonesian Basic and Experimental Health Sciences Vol. 14 No. 1 (2025): November
Publisher : Rumah Sakit Umum Daerah Dr. Moewardi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.11594/ibehs.vol14iss1pp98-102

Abstract

IntroductionSevere cutaneous adverse reactions (SCARs) such as Stevens-Johnson Syndrome (SJS), Toxic Epidermal Necrolysis (TEN), and DRESS are rare but life-threatening conditions requiring intensive inpatient care. Corticosteroids remain the main therapy but may prolong hospitalization and increase complications. Combining corticosteroids with cyclosporine has been considered to improve patient outcomes. This study explored healthcare professionals’ perspectives on the impact of this therapy combination on hospitalization duration for SCAR patients. MethodsA qualitative exploratory study was conducted at Dr. Moewardi General Hospital, Surakarta (August–October 2023). Purposive sampling recruited 12 healthcare professionals (3 consultants, 5 residents, 4 nurses) involved in SCAR management. Semi-structured interviews explored diagnostic confidence, treatment approaches, and hospitalization duration. Data were analyzed using thematic analysis. ResultPhysicians reported high diagnostic confidence, with typical hospital stays ranging from 14–30 days. Most favored corticosteroid–cyclosporine combination therapy, perceiving faster recovery and fewer complications. Barriers included limited drug availability, unfamiliarity with dosing, and safety concerns. Nurses emphasized wound care challenges, infection risks, and psychosocial needs. Both groups underlined the importance of multidisciplinary collaboration and family involvement in optimizing patient outcomes. ConclusionHealthcare professionals perceive corticosteroid–cyclosporine combination therapy as potentially effective in shortening hospitalization and reducing complications among SCAR patients. Institutional support, clinician training, and further clinical research are recommended to strengthen its implementation.
The Effectiveness of Topical Insulin for Ulcer Healing: A Pilot Study: A Pilot Study Nareswari, Adniana; Rosmarwati, Ervina; Wijayawati, Merlina; Oktiningrum, Hastika Dwi; Yasmin, Aulia
Indonesian Basic and Experimental Health Sciences Vol. 14 No. 2 (2026): April
Publisher : Rumah Sakit Umum Daerah Dr. Moewardi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.11594/ibehs.vol14iss2pp123-127

Abstract

Introduction Chronic ulcers continue to pose a major clinical challenge, contributing to significant morbidity and mortality. These conditions are frequently associated with diabetes, venous disorders, neuropathy, and other systemic illnesses. Conventional treatments often yield suboptimal results, encouraging investigation into alternative approaches such as topical insulin. This study aims to evaluate the effectiveness and safety of topical insulin in promoting ulcer healing. Method A pre-post interventional pilot study was conducted at Dr. Moewardi General Hospital from September to October 2024. Seven patients aged 40-80 years with grade II-III ulcers were treated with a topical insulin solution (10 IU insulin in 1 mL saline), applied once daily for 14 days. Ulcer size was measured on days 0, 7, and 14. Adverse effects were also monitored. Result Out of seven participants, three showed significant improvement in ulcer size (75-100% reduction), three showed mild to moderate improvement (8-26%), and one had no response. No local or systemic adverse events, including hypoglycemia, were observed. Factors such as limited patient mobility affected follow-up adherence. Discussion The findings suggest topical insulin enhances ulcer healing through mechanisms involving cell proliferation, angiogenesis, and anti-inflammatory effects, consistent with prior studies. However, the small sample size and loss to follow-up limit generalizability. Further trials are required to confirm its clinical utility. Conclusion Topical insulin appears to be a safe and potentially effective adjunct therapy for ulcer healing in both diabetic and non-diabetic patients. Larger-scale studies with control comparisons are needed to confirm its efficacy and optimize treatment protocols.
Henoch–Schönlein Purpura with Gastrointestinal Involvement in an Adult Patient: A Case Report Lamsir, Seno; Yustin Ellistasari, Endra; Rosmarwati, Ervina; Mawardi, Prasetyadi
Indonesian Basic and Experimental Health Sciences Vol. 14 No. 2 (2026): April
Publisher : Rumah Sakit Umum Daerah Dr. Moewardi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.11594/ibehs.vol14iss2pp111-115

Abstract

Introduction Henoch–Schönlein purpura (HSP), also known as IgA vasculitis, is a systemic small-vessel vasculitis characterized by IgA immune complex deposition. Although predominantly a childhood disease with a generally favorable prognosis, adult cases often exhibit more severe systemic involvement, particularly affecting the gastrointestinal tract and kidneys. Case A 22-year-old female presented with palpable purpura on the extremities, arthralgia, and melena. Physical examination revealed confluent purpuric lesions over the arms and legs. Endoscopy revealed esophagitis and antral gastritis. Skin biopsy demonstrated flattening of rete ridges and perivascular infiltrates, consistent with leukocytoclastic vasculitis. The patient was treated with intravenous methylprednisolone and supportive therapy, resulting in significant improvement of skin lesions, joint pain, and resolution of gastrointestinal bleeding. Discussion Adult HSP is less common but typically has a more severe course compared to pediatric cases. Gastrointestinal involvement, as seen in this case, may present as bleeding, ischemia, or ulceration, and can be life-threatening. Corticosteroids are effective in controlling inflammation and alleviating symptoms but do not prevent renal complications. Continuous renal monitoring is crucial, as kidney involvement remains the primary determinant of long-term prognosis. Conclusion This case highlights the clinical relevance of HSP in adults, where gastrointestinal manifestations may predominate and require aggressive management. Long-term follow-up, especially for renal involvement, is essential to improve outcomes.
Nail Abnormalities In Genodermatose Widhiati, Suci; Danarti, Retno; Budi Rustiawati, Cyntia Arum
Indonesian Basic and Experimental Health Sciences Vol. 14 No. 2 (2026): April
Publisher : Rumah Sakit Umum Daerah Dr. Moewardi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.11594/ibehs.vol14iss2pp128-134

Abstract

Introduction Nail abnormalities may serve as early indicators of various genodermatoses, either presenting in isolation or alongside systemic features. These abnormalities, though sometimes cosmetic, often hold significant diagnostic value, especially in inherited ectodermal disorders. Understanding the anatomy and embryology of the nail unit is crucial for identifying the origin and nature of such defects. Method This literature review was conducted by analyzing selected journal articles, case reports, and textbooks focusing on genodermatoses with distinct nail involvement. The analysis centered on the classification of nail abnormalities based on their anatomical origin: nail matrix, nail bed, or combined mesodermal-ectodermal defects. Results Findings revealed that nail abnormalities are prominent in several genodermatoses. Nail matrix defects are observed in congenital dyskeratosis, marked by nail dystrophy, leukoplakia, and mucocutaneous pigmentation. Nail bed defects, as seen in congenital pachyonychia and hydrotic ectodermal dysplasia, lead to thickened, dystrophic nails and associated skin changes. Combined mesodermal-ectodermal disorders, such as nail-patella syndrome, present with absent or hypoplastic nails alongside skeletal, renal, and ocular abnormalities. Each condition displayed specific nail manifestations that can aid early diagnosis. Discussion: The review emphasizes the importance of integrating knowledge of nail anatomy and development to differentiate between types of nail abnormalities. Identifying the anatomical origin aids in narrowing the differential diagnosis and can provide early clues to systemic genodermatoses, even before other clinical signs emerge. Conclusion: Nail abnormalities are important diagnostic markers in genodermatoses. Routine nail examination should be an integral part of dermatological assessments to facilitate early recognition and diagnosis of underlying genetic disorders.
Survival is Just the Beginning: Quality of Life in Patients (QoL) with Intraoral and Extraoral Squamous Cell Carcinoma (SCC) Mustawan, Mohamad Rifki Adli; Soewoto, Widyanti
Indonesian Basic and Experimental Health Sciences Vol. 14 No. 2 (2026): April
Publisher : Rumah Sakit Umum Daerah Dr. Moewardi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.11594/ibehs.vol14iss2pp116-122

Abstract

Introduction Squamous cell carcinoma (SCC) continues to be a health problem worldwide with far reaching effects not only on survival but on patient's quality of life (QoL). Health-related quality of life (HRQoL) assessment sheds lights on overall disease and its treatment impact. Method In this cross-sectional study was performed on 53 patients diagnosed with SCC, which included 36 intraoral and 17 extraoral cases. Sociodemographic data was collected and the QoL was assessed by using the European Organisation for Research and Treatment of Cancer Quality of Life Questionnaire (EORTC QLQ-C30) and short form-36 (SF-36). The data were analyzed using Mann-Whitney U test and Spearman’s correlation. Results Among 53 SCC patients (36 intraoral, 17 extraoral; mainly middle-aged females of low socioeconomic status), overall Quality of Life (QoL) score did not differ between groups. In summary, the analyses revealed additional differences in QoL determinants as patients with intraoral head and neck Squamous cell carcinoma (SCC) QoL was driven towards functional domains whereas symptom-related determinants were dominated for extraoral SCC patients. There was no statistically significant difference in overall QoL (p = 0.839) between groups. Discussion This study provides evidence suggesting that QoL impairments associated with intraoral SCC and with extraoral SCC are primarily driven by symptom burden and pain, and that there is no difference between the groups in overall quality of life (QoL). The relationship between QoL and functional limitations was more pronounced for intraoral SCC, whereas symptom severity had a greater impact on mental status for extraoral SCC. These results are consistent with existing evidence that SCC affects multiple dimensions of health irrespective across the sites of the tumor. There are QoL data available for management of various chronic conditions, and they highlight the importance of more comprehensive, patient-centred care that emphasizes early symptom control along with optimal pain management and functional rehabilitation strategies. Conclusion Demographics do not affect the quality of life of SCC patients, as clinical variables like symptoms, pain, and limitations impact it more than demographic data. Patients with intraoral SCC also experienced moderate QoL, highlighting opportunities for better symptom control and psychosocial support to improve overall patient health-related QoL.
The Effect Of Proctor Supervision Model On Nurses' Compliance Level In Performing Wound Care According To SOP (Standard Operating Procedure) In Flamboyan 5 Surgical Inpatient Ward At Dr. Moewardi Regional General Hospital Tri Mulyanto, Warih; Ardian Oktavia, Faisal; Balighoh, Farhatul; Fatiha, Chalista Ayu
Indonesian Basic and Experimental Health Sciences Vol. 14 No. 2 (2026): April
Publisher : Rumah Sakit Umum Daerah Dr. Moewardi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.11594/ibehs.vol14iss2pp103-110

Abstract

Introduction Nurse compliance with wound care procedures remains a challenge in ensuring patient safety, particularly in surgical wards that require precision in clinical practice (Kamil & Wardhani, 2020; Wang & Lee, 2020). Inconsistent adherence to standard operating procedures (SOPs) may increase the risk of infection and affect the quality of nursing services. Therefore, effective supervision is required to improve compliance in clinical practice. Objective This study aimed to analyze the effect of the Proctor supervision model on nurses’ compliance in performing wound care according to standard operating procedures in the Flamboyan 5 Surgical Inpatient Ward at Dr. Moewardi Regional General Hospital. Method This study used a quasi-experimental design with a pre-test and post-test approach without a control group. A total of 19 nurses were selected using the total sampling technique. Data were collected using a Guttman scale observation sheet consisting of 26 wound care procedure indicators. Data were analyzed using univariate and bivariate methods. Because the data were not normally distributed, the Wilcoxon Signed Rank Test was used to examine differences in compliance scores before and after the intervention. Results Before supervision, all respondents (100%) were categorized as partially compliant. After the Proctor supervision intervention, seven nurses (36.8%) were categorized as compliant, while twelve nurses (63.2%) remained partially compliant. Statistical analysis showed a significant difference between pre- and post-intervention compliance scores (p < 0.05). Conclusion The Proctor supervision model can be considered a useful strategy to improve nurse compliance in wound care practice and to support patient safety and nursing care quality.

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