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Profil Flebitis pada Anak: Studi di Instalasi Rawat Inap RSUD Dr. Moewardi Surakarta Bunga, Gita Hening; Widhiati, Suci
Cermin Dunia Kedokteran Vol 45, No 8 (2018): Alopesia
Publisher : PT. Kalbe Farma Tbk.

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (109.945 KB) | DOI: 10.55175/cdk.v45i8.622

Abstract

Pendahuluan. Penggunaan kateter vena perifer bertujuan memasukkan cairan, obat, dan produk darah ke dalam tubuh. Komplikasi yang paling sering adalah tromboflebitis dan lebih sering terjadi pada anak. Beberapa faktor yang dapat mempengaruhi terjadinya flebitis pada anak perlu diketahui. Metode. Penelitian deskriptif menggunakan data rekam medis pasien anak di instalasi rawat inap RSUD dr. Moewardi Surakarta bulan Januari 2014-Desember 2016. Hasil. Dari 3037 pasien, 30 terdiagnosis flebitis (0,98%). Lama rawat inap terutama lebih dari 14 hari (10 pasien - 33,33%). Diagnosis terbanyak adalah keganasan hematologi (9 - 30%). Terapi intravena terbanyak adalah antibiotik sejumlah 22 (73,33%). Sebanyak 12 pasien (54,54%) mendapat 2 macam antibiotik intravena. Sebagian besar pasien mendapat 3-4 obat intravena pada saat bersamaan (56,67%). Diskusi. Beberapa faktor berkaitan dengan terjadinya flebitis. Penggunaan antibiotik multipel dan beberapa jenis obat pada saat bersamaan diperkirakan mempengaruhi risiko flebitis. Diduga sebagian kasus flebitis tidak dilaporkan ataupun tidak terdiagnosis. Diperlukan penelitian lebih lanjut kejadian flebitis anak agar dapat menjadi masukan untuk langkah pencegahan.Introduction. Peripheral venous catheter is used to administer fluids, drugs and blood products into the body. The most common complication is thrombophlebitis, more common in children. Several factors can affect the occurrence of phlebitis in children. Methods. This study is descriptive study using pediatric medical records in Dr. Moewardi General Hospital Surakarta during January 2014-December 2016. Results. Among 3037 children inpatients, 30 diagnosed with phlebitis (0.98%). Most hospitalization period was more than 14 days (10 children - 33.33%). Most common diagnosis was haematological malignancy (9 children - 30%). The most common intravenous therapy is antibiotics (22 children - 73,33%). Twelve patients (54.54%) received 2 intravenous antibiotics. Most patients (56.67%) received 3-4 intravenous medications simultaneously. Discussion. Several factors related to the occurrence of phlebitis were length of hospitalization, patient’s hematological condition, type and amount of drugs, especially antibiotics. Multiple antibiotics, also multiple drugs, given simultaneously may have a role in phlebitis’ incidence. Many phlebitis cases may not be reported or properly diagnosed. Further researches are needed to obtain the incidence of phlebitis in children for appropriate measures to prevent phlebitis.
Manifestasi Kulit Terkait Defisiensi Nutrisi pada Anak Dewi, Putti Fatiharani; Aliwardani, Ambar; Rosita, Fiska; Widhiati, Suci
Cermin Dunia Kedokteran Vol 48, No 10 (2021): CME - Continuing Medical Education
Publisher : PT. Kalbe Farma Tbk.

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (254.241 KB) | DOI: 10.55175/cdk.v48i10.1513

Abstract

Manifestasi kulit dapat menjadi gejala dan tanda awal defisiensi nutrisi pada anak. Defisiensi nutrisi tersebut antara lain malnutrisi protein energi, defisiensi asam lemak esensial, defisiensi vitamin A, pelagra, defisiensi kobalamin, scurvy dan defisiensi zink. Beberapa malnutrisi dapat memberikan gejala kulit cukup khas dan terkadang tumpang tindih. Gejala kulit awal pada defisiensi nutrisi anak dapat didiagnosis dini sehingga dapat segera diberi tatalaksana suplementasi yang tepat untuk mencegah komplikasi yang lebih berat.Skin manifestations can be an early symptom and sign of nutritional deficiency in children. Such nutritional deficiencies include energy protein malnutrition, essential fatty acid deficiency, vitamin A deficiency, pellagra, cobalamin deficiency, scurvy, and zinc deficiency. Some malnutritions can provide quite typical and sometimes overlapping skin symptoms. Early skin symptoms in a child's nutritional deficiency can be diagnosed early and immediately given appropriate supplementation procedures to prevent more severe complications.
Clinical diagnostic matrix (CDM) as a tool to diagnose subtypes of epidermolysis bullosa cases in children Widhiati, Suci; Marcella, Benazier; Dewi, Susanti Rosmala; Paramitasari, Anggana Rafika; Ellistari, Endra Yustin; Julianto, Indah
Journal of General - Procedural Dermatology & Venereology Indonesia Vol. 3, No. 2
Publisher : UI Scholars Hub

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Abstract

Background: Epidermolysis bullosa (EB) is a rare genetic skin disease characterized by trauma-induced blisters, which appear shortly after birth. Immunofluorescence antigen mapping and mutational analysis are essential for establishing an accurate diagnosis of EB. However, in limited resource settings like in Indonesia, such techniques are not always readily available, forcing many clinicians to diagnose EB based on clinical features alone that is often inaccurate. Recently, a novel clinical diagnostic matrix (CDM) tool has been developed to improve the diagnostic accuracy of EB in such settings. Case Illustration: We examined clinical photographs and medical records of patients registered at the Dr. Moewardi hospital with a provisional diagnosis of EB since 2013 to 2017 and completed the 19 clinical manifestations required for the CDM’s electronic version. Discussion: CDM provides a diagnosis of the EB subtypes, which cannot be concluded in advance from the previous three cases, although histopathological examination have been carried out. Since immunofluorescence examination and genetic mapping are inaccessible in Indonesia, the CDM gave a brief possibility of diagnosing EB subtypes. Completing the CDM took less than five minutes and the result was available immediately after clinical features data input. Conclusion: CDM appears to be practical, easy to be used and helpful in characterizing EB, especially in limited resource settings. Moreover, it helps in clear documentation of clinical features in an EB patient that could be useful for accurate phenotype-genotype correlations in the future.
The differences of blood type in relation to psoriasis and its onset: Cross sectional study Dharmawan, Nugrohoaji; Widhiati, Suci; Oktavriana, Triasari; Harahap, Irene Jessica Pinarsinta
Journal of General - Procedural Dermatology & Venereology Indonesia Vol. 5, No. 3
Publisher : UI Scholars Hub

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Abstract

Background: Psoriasis is a chronic skin disease caused by inflammatory response and attacks 2% of population, with the prevalence influenced by age, geographical location, and genetic background. Until this day, there are several studies that discuss about the relationship between blood type with disease. However, discussion about the difference between blood type and the relationship with skin disease remains limited. The objective of this study is to know the relationship between blood type, psoriasis, and onset of psoriasis.Methods: This study adopted cross-sectional design of analytic observational study. The subjects of this study were patients in Department of Dermatology and Venereology at Dr. Moewardi General Hospital and UNS Hopital in Surakarta. The blood types were determined by two methods; by using ABD-Pad measurement tools that able to see the reaction of antigen and antibody in short time and by using the hospital’s laboratory facility where sample was taken. Anamnesis were done to collect data about the onset of psoriasis. Chi-square (X2) statistical test was used to analyze the data.Results: Total sample of this study were 62 people with 31 subjects (50%) were psoriasis patients and 31 others (50%) are non-psoriasis patients. Chi-square test (X2) between blood type with psoriasis and blood type with the onset of psoriasis are p = 0.269 and p = 0.188 respectively. Conclusion: The significance level used was p < 0.05, therefore there’s no significant correlation between blood type with psoriasis and the onset of psoriasis.
The relationship between increased body mass index with transepidermal water loss: a comparative study Yudhistira, Muhammad Yurizar; Kusumawardani, Arie; Widhiati, Suci; Mulianto, Nurachmat
Journal of General - Procedural Dermatology & Venereology Indonesia Vol. 6, No. 1
Publisher : UI Scholars Hub

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Abstract

Background: Obesity affect significant populations on all ages. The relationship between obesity and metabolic diseases is known but a dermatological link is rarely explained. Transepidermal water loss (TEWL) is one of the measurement tools used to define the skin’s barrier function by measuring the amount of water that evaporates through the skin in aspecific amount of time. Although several studies on TEWL are available but discussion about the correlation between TEWL and body mass index (BMI) is still limited. This study aims to evaluate the correlation between TEWL and BMI. Methods: This research is a single-center study with analytical cross-sectional design that includes healthy subjects among medical students aged 18 to 23 years old in Universitas Sebelas Maret. A questionnaire was used to ensure that all subjects met the criteria. Chi-square and Pearson were used to analyze the observed variables.Results: The total sample in this study was 62 participants, with a majority of female (59.7%) and ranged from 21 to 23 years (74.2%). The ratio of normoweight and overweight/obese was 1:1. The results demonstrated significant difference and positive correlation between increased BMI with TEWL (pConclusion: This study showed a significant correlation between increased body mass index and transepidermal water loss. Overweight participants tend to develop high values of TEWL which reflect a disruption of skin barrier. Further research on other influencing factors with larger samples and more study centers are needed.
Discoid lupus erythematosus in an 8-year-old girl: A rare case Febriani, Dina; Kusumawardani, Arie; Widhiati, Suci
Journal of General - Procedural Dermatology & Venereology Indonesia Vol. 7, No. 1
Publisher : UI Scholars Hub

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Abstract

Background: The occurrence of discoid lupus erythematosus in children is uncommon. The global prevalence of childhood-onset SLE (cSLE) varies between 3.3 and 8.8 cases per 100,000 children. The objective of this article was to present a case of DLE in a child, aiming to establish a diagnosis, provide suitable management, and consider the potential risk of developing SLE. Case Illustration: An 8-year-old girl visited the polyclinic at Dr. Moewardi General Hospital complaining of reddish spots, scales with a black core, and a burning sensation on her cheeks and nose for three months. Initially, small pimples and reddish spots appeared on her face, which grew in size. A dermatological examination of the face showed partly hyperpigmented erythematous plaques, multiple well-defined scales, and partly merged plaques were observed. Discussion: In pediatric cases of DLE, the primary treatment approach involves minimizing exposure to UV radiation using sunscreen. Low-potency topical corticosteroids were administered on active lesions on the facial region. Systemic therapy may be considered, which may involve using immunomodulatory medications such as systemic corticosteroids and antimalarials. However, in this patient’s case, antimalarials were not given as clinical improvement was observed with topical corticosteroids. Conclusion: This case’s DLE diagnosis is based on the patient’s history, physical, and supporting examination. Education on risk factors and drug selection according to complaints is the key to successful therapy for DLE patients.
Hand Eczema in Nurses in COVID-19 Treatment Room: Frequency of Handwashing, Hand Sanitizer, Moisturizer, and Duration of Latex Gloves Use Rosmarwati, Ervina; Widhiati, Suci; Novriana, Dita Eka; Rahma, Alfina; Kariosentono, Harijono; Irawanto, Muhammad Eko; Kusumawardani, Arie; Ellistasari, Endra Yustin; Oktavriana, Triasari
Berkala Ilmu Kesehatan Kulit dan Kelamin Vol. 34 No. 2 (2022): AUGUST
Publisher : Faculty of Medicine, Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/bikk.V34.2.2022.92-98

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Background: The COVID-19 pandemic causes health workers to use level 2 and level 3 personal protective equipment. Hand washing and the use of latex gloves are important in limiting the spread of COVID-19, but they can potentially induce hand eczema and skin pH disturbance if used too frequently. Purpose: Determine the correlation between the frequency of handwashing and duration of using hand sanitizer and moisturizer as well as skin pH level on the incidence of hand eczema in nurses in the COVID-19 treatment room at RSUD Dr. Moewardi Surakarta. Methods: This cross-sectional study was conducted in the COVID-19 treatment room at RSUD Dr. Moewardi Surakarta with 90 nurses as subjects. A validated questionnaire carried out the frequency of handwashing, hand sanitizer, moisturizer, duration of using latex gloves, and hand eczema complaints. The subject's pH assessment was conducted after 4-5 hours in the COVID-19 treatment room. Data were analyzed bivariately with a Spearman rank correlation test. Result: There was a significant correlation with the incidence of hand eczema with the frequency of handwashing with soap (r=0.305 and p=0.003) and the duration of using latex gloves (r=0.328 and p=0.002) with a weak category correlation (r=0.200-0.399). The frequency of using hand sanitizer, moisturizer, and skin pH did not correlate with the incidence of hand eczema. Conclusion: Frequency of handwashing and the duration of using latex gloves correlated with the incidence of hand eczema, meanwhile frequency of using hand sanitizer, using moisturizer, and skin pH didn't correlate with the incidence of hand eczema.
The Relationship between Hygiene Behaviour and Acne Vulgaris Incidence in Medical Students Sebelas Maret University Hapsari, Jasmine Rahmi; Murasmita, Alamanda; Widhiati, Suci; Kusumawardani, Arie
Berkala Ilmu Kesehatan Kulit dan Kelamin Vol. 34 No. 2 (2022): AUGUST
Publisher : Faculty of Medicine, Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/bikk.V34.2.2022.125-129

Abstract

Background: Hygiene behaviour is a person's actions in maintaining cleanliness to prevent the spread of infectious disease by cutting off the transmission of microorganisms that cause infection both in the community and in the health service. Various diseases caused by poor hygiene behaviour are diarrhea, dengue fever, leptospirosis, acute respiratory tract infections, typhoid fever, and various skin infections. One of the infectious skin diseases that affects almost the entire population is acne vulgaris. It is the highest disease prevalence worldwide and ranked 8th with 645.499.139 sufferers. Purpose: To determine the relationship between hygiene behaviour and acne vulgaris incidence in medical students at Sebelas Maret University. Methods: This study was an observational analytical study with a cross-sectional approach. This study was conducted on 45 male medical students at Sebelas Maret University. The questionnaire used was Hygiene Inventory (HI23). Data were analyzed using Fisher's Exact correlation test. Result: There is no relationship (p = 0.720) between hygiene behaviour and acne vulgaris incidence in medical students of the Sebelas Maret University. Conclusion: Hygiene behaviour has no relationship with acne vulgaris incidence in medical students at Sebelas Maret University.
Laporan Kasus Acrodermatitis Enteropathica pada Anak 5 Tahun dengan Level Zink Serum Normal Nareswari, Adniana; Mochtar, Moerbono; Widhiati, Suci; Kusumawardani, Arie; Ellistasari, Endra Yustin; Julianto, Indah
MEDICINUS Vol. 34 No. 1 (2021): MEDICINUS
Publisher : PT Dexa Medica

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (123.849 KB) | DOI: 10.56951/medicinus.v34i1.51

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Acrodermatitis enterophatica (AE) is an inherited or acquired condition associated with zinc malabsorption. Clinical symptoms of AE are periorificial and acral dermatitis, alopecia, and diarrhea. Serum zinc levels usually decrease in AE patients. A 5-year-old boy presented with crusted erosion on the face, trunks and extremities that have been appeared for one year and worsened last month. It also accompanied by hair and eyebrow loss, diarrhea, and eating disorder. Patient was also malnourished. Dermatovenereology examination showed papules, patches, multiple erythematous plaques with squama, erosions with brownish yellow crust above located on perioral, periorbital, posterior trunk, inguinal, perianal, cubital, popliteal and dorsum pedis region. The oral region showed stomatitis and cheilitis. The orbital region showed conjunctival injection and eye discharge. The scalp, eyebrows and lashes showed total alopecia. Laboratory test showed normal serum zinc levels and decreased levels of alkaline phosphatase. The patient was diagnosed with acquired form of AE. Clinical improvement was seen after zinc supplementation. The diagnosis of AE cannot be made only by low serum zinc levels. If a classical triad of AE was found, we must be able to recognize it immediately, thus prompt and appropriate therapy could be given.
Sukralfat as a Therapy for Reducing Itching and Repairing the Skin Barrier: A Systematic Review Alia, Vrenda; Widhiati, Suci; Oktavriana, Triasari; Lidjaja, Lifesia Natali; Noviani, Laura
Journal La Medihealtico Vol. 5 No. 4 (2024): Journal La Medihealtico
Publisher : Newinera Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37899/journallamedihealtico.v5i4.1508

Abstract

Sucralate is an aluminum salt from sucrose octasulfate that is known for its anti-ulcer activity, mucosal protection, and anti-mucositis potential. Recently, sucralfat has been used topically for the healing of various epithelial wounds, including ulcers, inflammatory dermatitis, mucositis, and burns. This systematic review aimed to evaluate the effectiveness of sucralfat as a topical therapy in reducing itching (pruritus) and improving the skin barrier. The analysis method used is Preferred Reporting Items for Systematic Review and Meta-Analysis (PRISMA). A literature search was conducted on studies from 2004 to 2024 using keywords such as "sucralfate", "pruritus", "dermatitis", and "skin barrier" on PubMed, ProQuest, Science Direct, and Scopus databases. Inclusion criteria include topic relevance, research design, human subjects, and United Kingdom-speaking studies. Of the 141 articles found, 7 articles met the inclusion criteria. These studies involved a total of 605 subjects from different countries and used clinical trial methods and randomized controlled trials. The results showed that topical sucralfat was effective in reducing itching and improving the skin barrier in various skin conditions such as diaper dermatitis, chronic ulcers, and postoperative wounds. Sukralfat shows great potential in wound healing and skin barrier repair through the mechanism of protective layer formation, increased expression of epidermal growth factors, and anti-inflammatory properties. This effect indirectly helps reduce pruritus which often occurs due to damage to the skin barrier. Topical succulthate is effective in reducing itching and repairing the skin barrier, making it a promising therapy for a variety of inflammatory and ulcerative skin conditions.