Genbinesia Journal of Biology
The Genbinesia Journal of Biology particularly focuses on the core disciplines in biology, they are: astrobiology, bacteriology, behavioural science, biochemistry, biodiversity, bioethics, bioinformatics, biomathematics, biophysics, biopolymers, biostatistics, biotechnology, botany, cell biology, conservation, crystallography of macromolecules, developmental biology, ecology, entomology, evolutionary biology, genetics, genomics, glycobiology, immunology, macromolecules, marine & aquatic biology, mathematical & computational biology, medicine, microbiology, molecular biology, mycology, nanoscience & nanotechnology, neurobiology, neuroscience, ornithology, paleobiology, paleontology, parasitology, pharmacology, physiology, plant biology, proteins & peptides, proteomics, radiation biology, reproductive biology, soil biology, structural biology, systems biology, techniques in biology, theoretical & mathematical biology, virology, zoology, and interdisciplinary applications in biology.
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<![CDATA[DNA damage, inflammation, and cellular senescence investigation in SARS-CoV-2 infection: A short review ]]>
<![CDATA[Kharisma, Viol Dhea]]>;
<![CDATA[Ansori, Arif Nur Muhammad]]>;
<![CDATA[Murtadlo, Ahmad Affan Ali]]>;
<![CDATA[Turista, Dora Dayu Rahma]]>;
<![CDATA[Tamam, Muhammad Badrut]]>;
<![CDATA[Ullah, Md. Emdad]]>;
<![CDATA[Jakhmola, Vikash]]>
<![CDATA[ Genbinesia Journal of Biology Vol. 2 No. 3 (2023): July 2023 ]]>
Publisher : <![CDATA[Generasi Biologi Indonesia ]]>
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DOI: 10.55655/genbinesia.v2i3.35
<![CDATA[SARS-2 infection is predicted to trigger DNA damage due to excessive inflammatory responses from the immune system such as cytokine storms. The cytokine storm leads to an increase in oxidative stress in cells, possibly triggering senescence through activation of the DNA damage response (DDR) signaling pathway. Alterations in the DDR pathway that induce cellular senescence have been identified due to the regulation of viral proteins that lead to impaired DNA repair. However, previous studies have not examined the relationship between DNA damage, inflammation, and cellular senescence. In this short review, we will discuss with a simple perspective why SARS-CoV-2 infection can accelerate the cellular senescence process and its relationship with the inflammatory response.]]>
<![CDATA[The utilization of marigold (Tagetes erecta L.) for traditional ceremonies in Indonesia: A systematic review ]]>
<![CDATA[Raihandhany, Reza]]>;
<![CDATA[Kurniawan, Bima]]>
<![CDATA[ Genbinesia Journal of Biology Vol. 2 No. 3 (2023): July 2023 ]]>
Publisher : <![CDATA[Generasi Biologi Indonesia ]]>
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DOI: 10.55655/genbinesia.v2i3.37
<![CDATA[Ethnobotanical heritages in Indonesia are exceptionally diverse because of the multicultural, multi-religious practice, and acculturation between them. The mega-biodiverse island nation is home to more than 800 ethnicities and naturally acts as sanctuary for the lush tropical ecosystems and its inhabitants. The hospitable nature of Indonesian land provides asylum for numbers of plants, including non-native species. Marigold (Tagetes erecta), a non-native ornamental plant that exhibits distinct showy flowers is cultivated and extensively grown in Indonesian lands. Beside being used as ornamental plants, some of the local communities are using marigold as a part in conducting their traditional ceremonies. This article provides some recorded traditional usage of marigold in traditional ceremonies of Indonesian communities from scientific articles. Significant usages of marigold are notably practiced by Hindu communities in Bali, Java (Tengger) and Lombok as part of their respective traditional-religious ceremonies. Vibrant color of the flower, its availability throughout the year, and easiness of cultivation are desirable traits that keep marigold usages significant. Local beliefs value marigold’s prominent flower color because it represents their Lord. The presence of marigold and its significant usage in the local communities provides space for native species to grow.]]>
<![CDATA[Biodiversity of fruit plants (edibles) at the Kentingan Campus of Universitas Sebelas Maret, Surakarta, Central Java, Indonesia ]]>
<![CDATA[Afifah, Ratih Nur]]>;
<![CDATA[Rezapratama, Muhammad Syavy]]>;
<![CDATA[Isa, Mukhlisah Nadya]]>;
<![CDATA[Nugroho, Gilang Dwi]]>;
<![CDATA[Setyawan, Ahmad Dwi]]>
<![CDATA[ Genbinesia Journal of Biology Vol. 2 No. 3 (2023): July 2023 ]]>
Publisher : <![CDATA[Generasi Biologi Indonesia ]]>
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DOI: 10.55655/genbinesia.v2i3.38
<![CDATA[Urban areas have the potential to support food supply even in limited quantities due to limited green open land, including edible fruits. This study aims to determine the biodiversity of fruit plants (edibles) at the Kentingan Campus of Universitas Sebelas Maret (UNS), Surakarta, Central Java, Indonesia. Data were collected by survey methods with cruising techniques, accompanied by a calculation of the ecological index in December 2022. Survey methods with cruising techniques, namely by exploring the entire campus area to collect the required primary data, including the name of plant species, the number of individuals, coordinates and fruit documentation found from each species. Data is processed and analyzed using the calculation of the ecological index. Meanwhile, secondary data was obtained from IUCN to determine the status of conservation and Plants of the World Online to determine the authenticity of species. The results obtained that there are 55 species from 25 families fruit plants with the Shannon-Wiener Index in the medium category, which is 3.17. Furthermore, the Margalef Index is in the high category, which is 7.30, and the Simpson Dominance Index is in a low category, which is 0.077. Some species have the highest number of individuals, namely Musa x paradisiaca L. (Musaceae), with 327 individuals. On the other hand, Mangifera indica L. (Anacardiaceae) is a species found in all locations. From the data obtained, according to IUCN, there are several fruit plants with 23 species of Least Concern (LC) conservation status and Data Deficient (DD) conservation status, as many as two species. Meanwhile, based on data from Plants of the World Online, several fruit plants on the Kentingan Campus of UNS are native to Indonesian plants, namely Durio zibethinus Murray, Averrhoa bilimbi L, and Averrhoa carambola L.]]>
<![CDATA[Structure, composition and economic potential of molluscs (gastropods and bivalves) in the Lembupurwo Lagoon Beach, Kebumen, Central Java, Indonesia ]]>
<![CDATA[Rohman, Cahya Maulidta]]>;
<![CDATA[Kinanti, Asih]]>;
<![CDATA[Pramudita, Desma Asty]]>;
<![CDATA[Fadzilah, Fariz Pradana Adil]]>;
<![CDATA[Ramadhan, Muhammad Fadhil]]>;
<![CDATA[Faturrahman, Aqra Danial]]>;
<![CDATA[Aurina, Devi Mayang]]>;
<![CDATA[Dewi, Mini Ambarwati Kusuma]]>;
<![CDATA[Ainaya, Fadia Aulianissa]]>;
<![CDATA[Rachmalia, Fayza]]>;
<![CDATA[Fatikha, Layyinatssyifa A’yuni]]>;
<![CDATA[Nugroho, Gilang Dwi]]>;
<![CDATA[Yap, Chee Kong]]>;
<![CDATA[Setyawan, Ahmad Dwi]]>
<![CDATA[ Genbinesia Journal of Biology Vol. 2 No. 3 (2023): July 2023 ]]>
Publisher : <![CDATA[Generasi Biologi Indonesia ]]>
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DOI: 10.55655/genbinesia.v2i3.39
<![CDATA[The mangrove ecosystem is a productive ecosystem with economic and environmental functions. This research was conducted to determine the value of the ecological index and the economic potential of molluscs (Gastropods and Bivalvia) found in the Lembupurwo Lagoon Beach (part of Wawar River Estuary), Kebumen District, Central Java, Indonesia. First, mollusc sampling was carried out on a 10x10 meter plot. So its existence also needs to be known and studied more specifically. Then, the ecological index of the species found is calculated using the Shannon-Wiener Diversity Index, Evenness Index, Simpson Dominance Index, Margalef Species Richness Index, and individual Density of each species. In addition, for the economic potential of molluscs using secondary data from scientific journals. Analysis of the data obtained descriptively with the support of tables and pictures. The study results showed that there were 17 species of molluscs consisting of 12 species belonging to the gastropod class and five other species belonging to the bivalves. The families with the most common species are Neritidae=3, Ellobiidae=2, and Littorinidae=2. Whereas in the Bivalvia class, each family was only found one species. The total molluscs found had a density value of 3.95 ind/m2. The Diversity Index (H') of molluscs was 1.48 (moderate), Evenness Index was 0.52 (moderate), Margalef Richness Index was 1.71 (low), and Dominance Index was 0.28 (no species dominated). Then, for the economic potential of the mollusks found, the economic potential is dominated by the food sector. The species that have potential in the food sector include: Faunus ater Linnaeus 1758, Isognomon ephippium Linnaeus 1758, Pilsbryoconcha exilis I.Lea, 1838, Polymesoda expansa Mousson 1849, and Anadara antiquata Linnaeus 1758.]]>
<![CDATA[Molecular Mechanisms of Hepatitis C Virus (HCV) Triggering Normal Cell Transformation into Cancer: A Mini Review ]]>
<![CDATA[Dhea Kharisma, Viol]]>;
<![CDATA[Sima, Putri Melati]]>
<![CDATA[ Genbinesia Journal of Biology Vol. 2 No. 3 (2023): July 2023 ]]>
Publisher : <![CDATA[Generasi Biologi Indonesia ]]>
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DOI: 10.55655/genbinesia.v2i3.43
<![CDATA[Hepatitis C virus (HCV) infection has become a serious concern because it can trigger the severity of complications leading to hepatocellular carcinoma (HCC). HCV is a virus with single-stranded RNA (ssRNA) type genetic material, with virions composed of structural proteins such as glycoprotein, envelope, and core, then HCV also has nonstructural proteins such as NS3, NS4, NS4B, NS5A, NS5B. The development of HCV infection therapy has been carried out through direct-acting antiviral agents (DAAs) with the hope of achieving a reduction in mortality and HCC risk. However, these strategies cannot fully reduce the risk of HCC in patients who have recovered from HCV infection. This review briefly reviews several factors from the virus and host to trigger cellular transformation of hepatocytes into HCC. HCV infection can trigger the transformation of hepatocytes into cancer in the case of HCC influenced by two factors consisting of pro-oncogenic and growth factors. Pro-oncogenic of HCV initiates HCC through the release of ROS that triggers genetic mutations and upregulation of proliferation in hepatocytes, it allows internal cell factors to also work in the process of transformation into cancer such as increased growth factor activity for antiapoptotic response, survival, and proliferation to trigger increased severity of HCC.]]>
