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Analgesic Activity of Ethanolic Extracts of Karika Leaves (Carica pubescens) In Vivo Heru Sasongko; Sugiyarto Sugiyarto; Nur Rohman Efendi; Diah Pratiwi; Ahmad Dwi Setyawan; Tetri Widiyani
JPSCR: Journal of Pharmaceutical Science and Clinical Research Vol 1, No 2 (2016)
Publisher : Universitas Sebelas Maret

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (397.239 KB) | DOI: 10.20961/jpscr.v1i2.1938

Abstract

Karika (Carica pubescens)is a typical plant of the Dieng plateau. Previous study showed that Caricapubescenscontains chemical compound such as flavonoid that play role in analgesic activity. This study was aimed to determine the analgesic activity of etanolic extracts of karika leaves) in vivo using writhing method. The study was conducted on 25 male mice strain Swiss-Webster (20-30 g, 2-3 months) that were randomly divided into 5 groups. Group I was given distilled water 1 mL (p.o) as negative control, group II was given tramadol 50 mg/kgBW (p.o) as positive control, and group III-V received an etanolic extracts of karika leaves in 3 doses, i.e. 20 mg/kgBW, 40 mg/kgBW, and 80 mg/kgBW (p.o), respectively. Acetic acid 0,5% (v/v) was used as pain inductor.  The writhe was observed within 1 hour. Data analysis was carried out by using one way ANOVA. The result showed that the ethanol extract of leaves Karika (Carica pubescens) have activity as an analgesic at a dose of 20 mg / kg, 40 mg / kg and 80 mg / KgBW (p <0.05), chemically induced, where a dose of 80 mg / KgBW (p.o) produce the most high analgesic activity.
Phytochemical Composition of Selaginella spp. from Java Island Indonesia Chikmawati, Tatik; Setyawan, Ahmad Dwi; Miftahudin, Miftahudin
Makara Journal of Science Vol. 16, No. 2
Publisher : UI Scholars Hub

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Abstract

For a long time, people in West Java, Indonesia have used Selaginella as a traditional cure for several ailments including fever, minor wounds, broken bones, women’s health disorders or postnatal bleeding. However, information on the active compounds of the plant from Java Island has not been fully expounded. The objective of the research was to reveal the diversity of bioactive compounds and amentoflavone content of Selaginella from Java Island in order to optimize the use of this plant as a medicinal plant. Selaginella plants collected from 29 locations in Java were extracted and subjected to colorimetric and thin layer chromatography test to qualitatively analyze the bioactive compounds of alkaloid, phenol, and steroid. In addition, high performance liquid chromatography was performed to analyze the amentofalvone content of Selaginella extract. The research result showed that all the examined Selaginella species contained alkaloid, flavonoid, saponin, tannin, and steroid, but they did not contain hydroquinone. Seven of them contained the biflavonoid type of amentoflavone. The highest amentoflavone concentration, 6.87 ppm, was found in S. subalpina that originated from Gedung Songo, Central Java. Those results indicated that more than one Selaginella species originating from Java Island had marked potential for use as medicinal plants.
Dinamika Ekologi Lahan Basah dan Upaya Pelestarian Kawasan Suaka Margasatwa Rawa Singkil, Aceh Syahrani, Lathifa Putri Wiedhya; luthfia, Luthfia; Farikha, Khotrotun Nida; Alfiyah, Lunetta Khalis; Setyawan, Ahmad Dwi
Environmental Pollution Journal Vol. 4 No. 1: April 2024
Publisher : ECOTON: Ecological Observation and Wetlands Conservation

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.58954/epj.v4i1.174

Abstract

Suaka Margasatwa Rawa Singkil memiliki peran vital dalam melindungi jasa lingkungan, khususnya sebagai kontributor utama karbon di Pulau Sumatera. Meskipun demikian, kawasan ini menghadapi ancaman serius akibat penipisan lahan gambut yang menjadi target ekspansi pertanian dan perkebunan. Artikel ini bertujuan untuk mengungkap karakteristik ekologi lahan basah serta memberikan gambaran terkait upaya pelestarian alam di Suaka Margasatwa Rawa Singkil. Metode studi literatur digunakan untuk menganalisis data sekunder secara deskriptif kualitatif. Temuan menunjukkan hasil bahwa Suaka Margasatwa Rawa Singkil terdiri dari tanah gambut yang kaya akan bahan organik dan subur disertai keanekaragaman hayati yang melimpah. Kawasan ini rentan terhadap perubahan tutupan lahan dan vegetasi akibat deforestasi dan konversi lahan. Upaya konservasi melibatkan perlindungan hukum yang kuat, pengawasan, pengelolaan ekosistem, serta penyuluhan dan partisipasi masyarakat setempat.
Keanekaragaman dan fungsi vegetasi di jalur hijau Kelurahan Kotabaru, Kecamatan Gondokusuman, Kota Yogyakarta Firdausi, Eyda; Setyawan, Ahmad Dwi
Jurnal Pengelolaan Lingkungan Berkelanjutan (Journal of Environmental Sustainability Management) JPLB, Vol 9, No 2 (2025)
Publisher : Badan Kerjasama Pusat Studi Lingkungan (BKPSL) se-Indonesia bekerjasama dengan Pusat Penelitian Lingkungan Hidup IPB (PPLH-IPB)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36813/jplb.9.2.161-177

Abstract

The development of urban areas needs to be accompanied by an improvement to the quality and quantity of the environment by providing public green open spaces such as green belt roads. This study aims to determine the diversity of vegetation and the functions in the green belt of Kotabaru Village, Yogyakarta City. The research was conducted using survey method in 14 green lanes to identify the type and amount of vegetation during September - October 2023. Based on the results of the study, 1407 individuals were found from 49 plant species. The diversity index (H') in the range of 0.64 - 2.12 is in the low to medium category. The evenness index (E) in the range of 0.69 - 0.93 is in the medium to high category. The dominance index (C) ranged from 0.12 to 0.38, including in the low category in all types of habitus (herbaceous, shrubs, shrubs, trees, and epiphytes). Vegetation in the green belt in Kotabaru Village can provide ecological, social, and economic functions for the surrounding community but still needs optimization in other functions such as community education. In addition, maintenance of green spaces also needs to be considered in order to provide sustainable vegetation functions.
Biodiversity of fruit plants (edibles) at the Kentingan Campus of Universitas Sebelas Maret, Surakarta, Central Java, Indonesia Afifah, Ratih Nur; Rezapratama, Muhammad Syavy; Isa, Mukhlisah Nadya; Nugroho, Gilang Dwi; Setyawan, Ahmad Dwi
Genbinesia Journal of Biology Vol. 2 No. 3 (2023): July 2023
Publisher : Generasi Biologi Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55655/genbinesia.v2i3.38

Abstract

Urban areas have the potential to support food supply even in limited quantities due to limited green open land, including edible fruits. This study aims to determine the biodiversity of fruit plants (edibles) at the Kentingan Campus of Universitas Sebelas Maret (UNS), Surakarta, Central Java, Indonesia. Data were collected by survey methods with cruising techniques, accompanied by a calculation of the ecological index in December 2022. Survey methods with cruising techniques, namely by exploring the entire campus area to collect the required primary data, including the name of plant species, the number of individuals, coordinates and fruit documentation found from each species. Data is processed and analyzed using the calculation of the ecological index. Meanwhile, secondary data was obtained from IUCN to determine the status of conservation and Plants of the World Online to determine the authenticity of species. The results obtained that there are 55 species from 25 families fruit plants with the Shannon-Wiener Index in the medium category, which is 3.17. Furthermore, the Margalef Index is in the high category, which is 7.30, and the Simpson Dominance Index is in a low category, which is 0.077. Some species have the highest number of individuals, namely Musa x paradisiaca L. (Musaceae), with 327 individuals. On the other hand, Mangifera indica L. (Anacardiaceae) is a species found in all locations. From the data obtained, according to IUCN, there are several fruit plants with 23 species of Least Concern (LC) conservation status and Data Deficient (DD) conservation status, as many as two species. Meanwhile, based on data from Plants of the World Online, several fruit plants on the Kentingan Campus of UNS are native to Indonesian plants, namely Durio zibethinus Murray, Averrhoa bilimbi L, and Averrhoa carambola L.
Structure, composition and economic potential of molluscs (gastropods and bivalves) in the Lembupurwo Lagoon Beach, Kebumen, Central Java, Indonesia Rohman, Cahya Maulidta; Kinanti, Asih; Pramudita, Desma Asty; Fadzilah, Fariz Pradana Adil; Ramadhan, Muhammad Fadhil; Faturrahman, Aqra Danial; Aurina, Devi Mayang; Dewi, Mini Ambarwati Kusuma; Ainaya, Fadia Aulianissa; Rachmalia, Fayza; Fatikha, Layyinatssyifa A’yuni; Nugroho, Gilang Dwi; Yap, Chee Kong; Setyawan, Ahmad Dwi
Genbinesia Journal of Biology Vol. 2 No. 3 (2023): July 2023
Publisher : Generasi Biologi Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55655/genbinesia.v2i3.39

Abstract

The mangrove ecosystem is a productive ecosystem with economic and environmental functions. This research was conducted to determine the value of the ecological index and the economic potential of molluscs (Gastropods and Bivalvia) found in the Lembupurwo Lagoon Beach (part of Wawar River Estuary), Kebumen District, Central Java, Indonesia. First, mollusc sampling was carried out on a 10x10 meter plot. So its existence also needs to be known and studied more specifically. Then, the ecological index of the species found is calculated using the Shannon-Wiener Diversity Index, Evenness Index, Simpson Dominance Index, Margalef Species Richness Index, and individual Density of each species. In addition, for the economic potential of molluscs using secondary data from scientific journals. Analysis of the data obtained descriptively with the support of tables and pictures. The study results showed that there were 17 species of molluscs consisting of 12 species belonging to the gastropod class and five other species belonging to the bivalves. The families with the most common species are Neritidae=3, Ellobiidae=2, and Littorinidae=2. Whereas in the Bivalvia class, each family was only found one species. The total molluscs found had a density value of 3.95 ind/m2. The Diversity Index (H') of molluscs was 1.48 (moderate), Evenness Index was 0.52 (moderate), Margalef Richness Index was 1.71 (low), and Dominance Index was 0.28 (no species dominated). Then, for the economic potential of the mollusks found, the economic potential is dominated by the food sector. The species that have potential in the food sector include: Faunus ater Linnaeus 1758, Isognomon ephippium Linnaeus 1758, Pilsbryoconcha exilis I.Lea, 1838, Polymesoda expansa Mousson 1849, and Anadara antiquata Linnaeus 1758.
Traditional ceremonies Mahesa Lawung as a traditional ritual of the Surakarta Palace in the Krendowahono Area, Central Java, Indonesia Syamsi, Rahma Nur; Safitri, Olinda Ayu; Putri, Rani Rachma Astining; Manullang, Raymond Hamonangan; Rinoa Salsabila Izdihar; Setyawan, Ahmad Dwi
Genbinesia Journal of Biology Vol. 3 No. 2 (2024): March 2024
Publisher : Generasi Biologi Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55655/genbinesia.v3i2.53

Abstract

Traditional ceremonies are a form of culture passed down from generation to generation, reflecting a society's values, beliefs, and identity. This research aims to find out and understand the meaning of the Mahesa Lawung traditional ceremony, the types of plants and animals used, and the knowledge of local communities in the Krendowahono Karanganyar Site area, Central Java. The method used in this research is a qualitative observation method, including direct interviews with each respondent. Data was collected through interviews and direct observation at the research location. The research data collected includes regional names, common names, scientific names of plants and animals species as well as parts used for offerings at Mahesa Lawung traditional ceremony, and the philosophies of the species that used in this traditional ceremony. There are 7 plants and 4 animal species used for the Mahesa Lawung traditional ceremony. The research results show that the Mahesa Lawung traditional ceremony is still carried out today, especially at the Krendowahono Site. Of the three villages used as research locations, almost all people knew about the ceremony but only heard about it and saw it briefly. The Mahesa Lawung traditional ceremony is a cultural history that needs to be preserved and maintained over time.