Genbinesia Journal of Biology
The Genbinesia Journal of Biology particularly focuses on the core disciplines in biology, they are: astrobiology, bacteriology, behavioural science, biochemistry, biodiversity, bioethics, bioinformatics, biomathematics, biophysics, biopolymers, biostatistics, biotechnology, botany, cell biology, conservation, crystallography of macromolecules, developmental biology, ecology, entomology, evolutionary biology, genetics, genomics, glycobiology, immunology, macromolecules, marine & aquatic biology, mathematical & computational biology, medicine, microbiology, molecular biology, mycology, nanoscience & nanotechnology, neurobiology, neuroscience, ornithology, paleobiology, paleontology, parasitology, pharmacology, physiology, plant biology, proteins & peptides, proteomics, radiation biology, reproductive biology, soil biology, structural biology, systems biology, techniques in biology, theoretical & mathematical biology, virology, zoology, and interdisciplinary applications in biology.
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Exploring the potential of Porang (Amorphophallus muelleri B.) as horticultural plants in Bocok Hamlet, Pondokagung Village, Kasembon District, Malang Regency, East Java
Hanik Isnaini;
Istiana Kautsarani;
Shofil Fikri
Genbinesia Journal of Biology Vol. 3 No. 1 (2023): November 2023
Publisher : Generasi Biologi Indonesia
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DOI: 10.55655/genbinesia.v1i3.29
Porang (Amorphophallus muelleri B.) is one of the well-known root crops in Indonesia because it has a lot of benefits and potential. One of the places that have a lot of Porang plantations is Bocok Hamlet, Pondokagung Village, Kasembon Sub-District, Malang Regency. Many people in this hamlet have Porang plantations, but the utilization of this plant is still not as optimal as other communities. Utilization of the potential of porang is still classified as less than optimal. Researchers conducted this research using 4 methods, namely initial surveys, determining research locations, observing morphological characters, and interviewing respondents. Based on the interviews conducted, the researchers found that porang has various potentials in several fields, such as in food, porang is made into several types of food ingredients such as flour. Besides that, many porang were exported to various countries such as Japan, England, and other countries. In addition, this plant also has abundant vitamin content for added nutrition and smooth metabolism.
Diversity and habitat preference of orchirds in R. Soerjo Forest Park, East Java, Indonesia
Rohmah, Laila Ainur;
Elyasa, Ayu Tya;
Nugraheni, Tunjung;
Pratama, Bella Pratiwi Kurnia;
Sakna, Bariznaba’us
Genbinesia Journal of Biology Vol. 3 No. 1 (2023): November 2023
Publisher : Generasi Biologi Indonesia
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DOI: 10.55655/genbinesia.v3i1.50
The diversity and habitat preferences of orchids in the natural tourist attraction area of R. Soerjo Forest Park (TAHURA) are not yet completely known. Lack of information and the activities of tourist visitors increase the risk of natural orchid habitat degradation. The aim of this research is to determine the diversity and habitat preferences of orchids in R. Soerjo Forest Park. The research design used a line transect method for orchid diversity data and a purposive sampling method with a plot measuring 10 × 10m for habitat preference analysis or environmental data. The research results show that there are 37 species of orchids in the natural tourist attraction area of R. Soerjo Forest Park, which is divided into 25 epiphytic orchids and 12 terrestrial orchids. The results of the Shannon-Wienner analysis show that the orchid diversity index value is 2.46, which is show a medium level of diversity. Dominant orchids grow at an altitude of 1,400–1,600 m.a.s.l. The most dominant orchid species are Nervilia punctata (558), Appendicula angustifolia (296), and A. elegans (130), with an evenness value of 0,32, 0,17, and 0,07. The dominance of N. punctata is influenced by the root shape, which is modified as a tuberous type. The results of redundancy analysis (RDA) show that the environmental variables that most influence the distribution of orchids are air temperature, soil pH levels, light intensity, and elevation.
Preliminary Study on Morphology, Meristics, and Morphometric Variations of Javan Spitting Cobra Naja sputatrix Boie, 1827 and Sumatran Spitting Cobra Naja sumatrana Müller, 1890
Dafa, Maula Haqul;
Yudha, Donan Satria;
Sulistio, Adian Dwi
Genbinesia Journal of Biology Vol. 3 No. 1 (2023): November 2023
Publisher : Generasi Biologi Indonesia
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DOI: 10.55655/genbinesia.v3i1.61
Cobras are venomous snakes from Elapidae Family widespread in Asia and Africa, including Indonesia. There are two species of cobras in Indonesia, the one being is Javan spitting cobra (Naja sputatrix Boie, 1827) and other is Sumatran spitting cobra (Naja sumatrana Müller, 1890). In Indonesia, N. sputatrix distributions are in Java, Bali, and Nusa Tenggara, meanwhile N. sumatrana spread across Sumatra and Kalimantan. Wide distribution means that there are also potentially wide variations in morphology, meristic, and morphometric characters. This research was conducted to determine variations of Javan and Sumatran spitting cobra with morphology, meristic, and morphometric characterization. Total number of 16 samples (N. sputatrix = 8, N. sumatrana = 8) were examined and measured. Visual observation focused on coloration and hood characteristics. Meristic observation uses head, dorsal, ventral, and subcaudal scalation. Morphometric observation measures SVL, TL, Tail, and HW. We found that hood morphology varies greatly between N. sputatrix and N. sumatrana. N. sumatrana differs between Sumatran and Borneo population. Morphometric variation is being less prominent with morphometric description that matches with previous literatures and researches.
In silico research of anti-CHIKF phytoconstituent-based from Physalis peruviana leaves via molecular docking and dynamics analyses
Setiyowati, Putri Ayu Ika;
Mahbubillah, M. Ainul;
Aini, Nur Sofiatul;
Rachmawati, Yuanita
Genbinesia Journal of Biology Vol. 3 No. 1 (2023): November 2023
Publisher : Generasi Biologi Indonesia
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DOI: 10.55655/genbinesia.v3i1.62
Chikungunya fever (CHIKF) is an infectious disease that has similar symptoms with dengue fever (DF). Several drugs have been offered to treat both dengue (DENV) and chikungunya virus (CHIKV). Investigating anti-CHIKF potential from nearby plants is one strategy to produce potential drug to reduce CHIKF in endemic countries. Physalis peruviana is one the promising object to be new anti-CHIKV drug candidate. This study aimed to analyze the anti-CHIKV agents from leaf parts of P. peruviana. Ligand and protein samples were collected from multiple sources. The phytoconstituents were evaluated their drug-likeness properties throughout SwissADME webservers. Selected ligands then docked via PyRX and measured the output by binding affinity. Visualization of the best outputs was carried out using BIOVIA Discovery Studio. CABS-flex was carried out to screen the RMSF of molecular dynamics activity of the best complex. The result showed that 1,2-benzenecarboxylic acid had the lowest binding affinity following suramin as control with -5.1 and -11.1 kcal/mol after targeting E2 domain protein of CHIKV. This led to the conclusion that 1,2-benzenecarboxylic acid could be forecast as predictive anti-CHIKF therapeutic candidate. Additional in vitro and in vivo studies are needed to validate this outcome.
3,3-dimethyl-octane from Physalis peruviana as promising anti-DENV via ADMET prediction of pkCSM open webserver
Prastiyanto, Muhammad Evy;
Solekha, Rofiatun;
Rohmah, Laila Ainur;
Yuanita Rachmawati;
Aini, Nur Sofiatul
Genbinesia Journal of Biology Vol. 3 No. 1 (2023): November 2023
Publisher : Generasi Biologi Indonesia
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DOI: 10.55655/genbinesia.v3i1.63
Dengue is caused by the dengue virus (DENV) and being prevalent in 100 tropical and subtropical countries including Indonesia. This disease is spread by Aedes mosquitoes. There is currently no clinically authorized medicine to treat the dengue fever. Physalis peruviana has ethnomedicine application and noted for its antioxidant activities. This study purpose to investigate the pharmacokinetics or ADMET of anti-DENV from leaf parts of P. peruviana. The phytoconstituents data were gathered from multiple sources. The drug property and ADMET prediction were assessed using pkCSM. Following online screening, 3,3-dimethyl-octane functioned as predictive anti-DENV therapeutic candidate. Further dry and wet lab studies are needed to validate this finding.